Novel synthesis of the isoflavone genistein

Synthesis

Volumn , Issue 10, 2010, Pages 1590-1592

  Denis, Jeffrey D St ^a   Gordon Iv, James S ^a   Carroll, Vincent M ^a   Priefer, Ronny ^a  

^a NIAGARA UNIVERSITY   (United States)

Author keywords

Coupling; Genistein; Green chemistry; Heterocycles; Isoflavone; Ring closure

Indexed keywords

GENISTEIN; GREEN CHEMISTRY; HETEROCYCLES; ISOFLAVONES; RING CLOSURE; RING CLOSURES;

CHEMICAL BONDS; ETHYLENE; ETHYLENE GLYCOL; KETONES; ORGANOMETALLICS; PALLADIUM; POLYETHYLENE GLYCOLS; POLYETHYLENE OXIDES;

SYNTHESIS (CHEMICAL);

1 [2 HYDROXY 4,6 BIS(METHOXYMETHOXY)PHENYL]ETHANONE; 3 (4 HYDROXYPHENYL) 5,7 BIS(METHOXYMETHOXY) 4H 1 BENZOPYRAN 4 ONE; 3 (DIMETHYLAMINO) 1 [2 HYDROXY 4,6 BIS(METHOXYMETHOXY)PHENYL]PROP 2 EN 1 ONE; 3 IODO 5,7 BIS(METHOXYMETHOXY) 4H 1 BENZOPYRAN 4 ONE; BASIC FIBROBLAST GROWTH FACTOR; GENISTEIN; PLATELET DERIVED ENDOTHELIAL CELL GROWTH FACTOR; REACTIVE OXYGEN METABOLITE; UNCLASSIFIED DRUG; VASCULOTROPIN;

ANGIOGENESIS; ANTINEOPLASTIC ACTIVITY; ARTICLE; BREAST CANCER; COLUMN CHROMATOGRAPHY; CYCLIZATION; DRUG EFFICACY; DRUG ISOLATION; DRUG POTENCY; DRUG SOLUBILITY; DRUG STRUCTURE; DRUG SYNTHESIS; HALOGENATION; HUMAN; IODINATION; LYMPH NODE METASTASIS; METASTASIS; PROSTATE CANCER;

EID: 77952048535     PISSN: 00397881     EISSN: 1437210X     Source Type: Journal    
DOI: 10.1055/s-0029-1219757     Document Type: Article

References (20)

1. Vasselin D A., Westwell A D., Matthews C S., Bradshaw T D., Stevens M F. G., J. Med. Chem. 2006 49 3973
2. Setchell K D., Brown N M., Desai P, Zimmer-Nechemias L, Wolfe B E., Brashear W T., Kirschner A S., Cassidy A, Heubi J E., J. Nutr. 2001 131 1362
3. Scholar E M., Toews M L., Cancer Lett. (Shannon, Irel.) 1994 2 159
4. Merlino G T., Xu Y H., Ishii S, Clark A J., Semba K, Toyoshima K, Yamamoto T, Pastan I, Science 1984 224 417
5. Messina M J., Persky V, Setchell K D., Barnes S, Nutr. Cancer 1994 21 114
6. Zhou J.-R, Nutr. Cancer Prev. 2006 325
7. Wietrzyk J, Opolski A, Madej J, Radzikowski C, In Vivo 2000 2 357
8. Wang S Y., Yang K W., Hsu Y T., Chang C L., Yang Y C., Neoplasma 2001 3 227
9. Perkin A G., Newbury F G., J. Chem. Soc., Trans. 1899 75 830
10. Baker W, Robinson R, J. Chem. Soc. 1928 3115
11. Shriner R L., Hull C J., J. Chem. Soc. 1945 228
12. Bass R J., J. Chem. Soc., Chem. Commun. 1976 78
13. Chang Y.-C, Nair M G., Santell R C., Helferich W G., J. Agric. Food. Chem. 1994 42 1869
14. Pelter A, Ward R S., Ashdown D H. J., Synthesis 1978 843
15. Farkas L, Gottsegen À, Nógrádi M, J. Chem. Soc., Perkin Trans. 1 1974 305
16. Sekizaki H, Yokosawa R, Chem. Pharm. Bull. 1988 36 4876
17. Sinkevich Y, Shchekotikhin A, Luzikov Y, Chem. Heterocycl. Compd. 2007 43 1252
18. Gammill R B., Synthesis 1979 901
19. Liu L, Zhang Y, Wang Y, J. Org. Chem. 2005 70 6122
20. Baker W, Chadderton J, Harborne J B., Ollis W D., J.Chem.Soc. 1953 1852