Role of glycoprotein Ibα mobility in platelet function

Thrombosis and Haemostasis

Volumn 103, Issue 5, 2010, Pages 1033-1043

  Van Der Wal, Dianne E ^a   Verhoef, Sandra ^a   Schutgens, Roger E G ^a   Peters, Marjolein ^b   Wu, Yaping ^a   Akkerman, Jan Willem N ^a  

^a UNIVERSITY MEDICAL CENTER UTRECHT   (Netherlands)

^b EMMA CHILDREN S HOSPITAL   (Netherlands)

Author keywords

Cold storage; Cytoskeleton; Glycoprotein Ib ; Platelet; Thromboxane A2

Indexed keywords

AMINO ACID DERIVATIVE; GLYCOPROTEIN IB ALPHA; N ACETYL BETA GLUCOSAMINIDASE; RISTOCETIN; THROMBOXANE A2; VON WILLEBRAND FACTOR; CD11B ANTIGEN; MONOCLONAL ANTIBODY; N ACETYLGLUCOSAMINE; THROMBIN RECEPTOR;

AMINO TERMINAL SEQUENCE; ANTIGEN BINDING; ARTICLE; CELL MEMBRANE; CONFORMATIONAL TRANSITION; CONTROLLED STUDY; CYTOSKELETON; HUMAN; HUMAN CELL; INCUBATION TEMPERATURE; PRIORITY JOURNAL; PROTEIN FUNCTION; THROMBOCYTE ACTIVATION; THROMBOCYTE ADHESION; THROMBOCYTE AGGLUTINATION; THROMBOCYTE AGGREGATION; THROMBOCYTE FUNCTION; BIOSYNTHESIS; BLOOD; BLOOD STORAGE; CAPPING PHENOMENON; CELL CULTURE; CHEMISTRY; GENETICS; IMMUNOLOGY; MACROPHAGE ACTIVATION; METABOLISM; PATHOLOGY; PHYSIOLOGY; PROTEIN BINDING; PROTEIN CONFORMATION; PROTEIN TRANSPORT; TEMPERATURE; THROMBOCYTE; THROMBOCYTE TRANSFUSION; VON WILLEBRAND DISEASE;

ACETYLGLUCOSAMINE; ANTIBODIES, MONOCLONAL; BLOOD PLATELETS; BLOOD PRESERVATION; CELLS, CULTURED; CYTOSKELETON; HUMANS; MACROPHAGE ACTIVATION; MACROPHAGE-1 ANTIGEN; PLATELET ACTIVATION; PLATELET GLYCOPROTEIN GPIB-IX COMPLEX; PLATELET TRANSFUSION; PROTEIN BINDING; PROTEIN CONFORMATION; PROTEIN TRANSPORT; RECEPTOR AGGREGATION; TEMPERATURE; THROMBOXANE A2; VON WILLEBRAND DISEASES; VON WILLEBRAND FACTOR;

EID: 77952037065     PISSN: 03406245     EISSN: None     Source Type: Journal    
DOI: 10.1160/TH09-11-0751     Document Type: Article

References (34)

1. Clemetson KJ, Clemetson JM. Platelet GPIb complex as a target for anti-thrombotic drug development. Thromb Haemost 2008; 99: 473-479.
2. Pennings MT, Derksen RH, van Lummel M, et al. Platelet adhesion to dimeric beta-glycoprotein I under conditions of flow is mediated by at least two receptors: glycoprotein Ibalpha and apolipoprotein E receptor 2′. J Thromb Haemost 2007; 5: 369-377.
3. Shen Y, Cranmer SL, Aprico A, et al. Leucine-rich repeats 2-4 (Leu60-Glu128) of platelet glycoprotein Ibalpha regulate shear-dependent cell adhesion to von Willebrand factor. J Biol Chem 2006; 281: 26419-26423.
4. Hartwig JH, DeSisto M. The cytoskeleton of the resting human blood platelet: structure of the membrane skeleton and its attachment to actin filaments. J Cell Biol 1991; 112: 407-425.
5. Englund GD, Bodnar RJ, Li Z, et al. Regulation of von Willebrand factor binding to the platelet glycoprotein Ib-IX by a membrane skeleton-dependent inside-out signal. J Biol Chem 2001; 276: 16952-16959.
6. Calverley DC, Kavanagh TJ, Roth GJ. Human signaling protein 14-3-3zeta interacts with platelet glycoprotein Ib subunits Ibalpha and Ibbeta. Blood 1998; 91: 1295-1303.
7. Du X. Signaling and regulation of the platelet glycoprotein Ib-IX-V complex. Curr Opin Hematol 2007; 14: 262-269.
8. Munday AD, Berndt MC, Mitchell CA. Phosphoinositide 3-kinase forms a complex with platelet membrane glycoprotein Ib-IX-V complex and 14-3-3zeta. Blood 2000; 96: 577-584.
9. Hoffmeister KM, Felbinger TW, Falet H, et al. The clearance mechanism of chilled blood platelets. Cell 2003; 112: 87-97.
10. Hoffmeister KM, Josefsson EC, Isaac NA, et al. Glycosylation restores survival of chilled blood platelets. Science 2003; 301: 1531-1534.
11. Badlou BA, Wu YP, Smid WM, et al. Platelet binding and phagocytosis by macrophages. Transfusion 2006; 46: 1432-1443.
12. Nichols WL, Hultin MB, James AH, et al. von Willebrand disease (VWD): evidence-based diagnosis and management guidelines, the National Heart, Lung, and Blood Institute (NHLBI) Expert Panel report (USA). Haemophilia 2008; 14: 171-232.
13. Huizinga EG, Tsuji S, Romijn RA et al. Structures of glycoprotein Ibalpha and its complex with von Willebrand factor A1 domain. Science 2002; 297: 1176-1179.
14. Hulstein JJ, de Groot PG, Silence K, Veyradier A, Fijnheer R, Lenting PJ. A novel nanobody that detects the gain-of-function phenotype of von Willebrand factor in ADAMTS13 deficiency and von Willebrand disease type 2B. Blood 2005; 106: 3035-3042.
15. Weeterings C, Adelmeijer J, Myles T, et al. Glycoprotein Ibalpha-mediated platelet adhesion and aggregation to immobilized thrombin under conditions of flow. Arterioscler Thromb Vasc Biol 2006; 26: 670-675.
16. Shen Y, Romo GM, Dong JF, et al. Requirement of leucine-rich repeats of glycoprotein (GP) Ibalpha for shear-dependent and static binding of von Willebrand factor to the platelet membrane GP Ib-IX-V complex. Blood 2000; 95: 903-910.
17. Badlou BA, Spierenburg G, Ulrichts H, et al. Role of glycoprotein Ibalpha in phagocytosis of platelets by macrophages. Transfusion 2006; 46: 2090-2099.
18. Fox JE. Linkage of a membrane skeleton to integral membrane glycoproteins in human platelets. Identification of one of the glycoproteins as glycoprotein Ib. J Clin Invest 1985; 76: 1673-1683.
19. Remijn JA, Wu YP, IJsseldijk MJ, et al. Absence of fibrinogen in afibrinogenemia results in large but loosely packed thrombi under flow conditions. Thromb Haemost 2001; 85: 736-742.
20. Litjens PE, Kroner CI, Akkerman JW, et al. Cytoplasmic regions of the beta3 subunit of integrin alphaIIbbeta3 involved in platelet adhesion on fibrinogen under flow conditions. J Thromb Haemost 2003; 1: 2014-2021.
21. Bergmeier W, Bouvard D, Eble JA et al. Rhodocytin (aggretin) activates platelets lacking alpha(2)beta(1) integrin, glycoprotein VI, and the ligand-binding domain of glycoprotein Ibalpha. J Biol Chem 2001; 276: 25121-25126.
22. Fijnheer R, Modderman PW, Veldman H et al. Detection of platelet activation with monoclonal antibodies and flow cytometry. Changes during platelet storage. Transfusion 1990; 30: 20-25.
23. Christodoulides N, Feng S, Resendiz JC, et al. Glycoprotein Ib/IX/V binding to the membrane skeleton maintains shear-induced platelet aggregation. Thromb Res 2001; 102: 133-142.
24. Wu Y, Asazuma N, Satoh K, et al. Interaction between von Willebrand factor and glycoprotein Ib activates Src kinase in human platelets: role of phosphoinositide 3-kinase. Blood 2003; 1; 101: 3469-3476.
25. Garcia A, Quinton TM, Dorsam RT, et al. Src family kinase-mediated and Erk-mediated thromboxane A2 generation are essential for VWF/GPIb-induced fibrinogen receptor activation in human platelets. Blood 2005; 106: 3410-3414.
26. Liu J, Pestina TI, Berndt MC, et al. Botrocetin/VWF-induced signaling through GPIb-IX-V produces TxA2 in an alphaIIbbeta3- and aggregation-independent manner. Blood 2005; 106: 2750-2756.
27. Wencel-Drake JD, Painter RG, Zimmerman TS, et al. Ultrastructural localization of human platelet thrombospondin, fibrinogen, fibronectin, and von Willebrand factor in frozen thin section. Blood 1985; 65: 929-938.
28. Uff S, Clemetson JM, Harrison T, Clemetson KJ, Emsley J. Crystal structure of the platelet glycoprotein Ib(alpha) N-terminal domain reveals an unmasking mechanism for receptor activation. J Biol Chem 2002; 277: 35657-35663.
29. Kasirer-Friede A, Ware J, Leng L, et al. Lateral clustering of platelet GP Ib-IX complexes leads to up-regulation of the adhesive function of integrin alpha IIbbeta 3. J Biol Chem 2002; 277: 11949-11956. (Pubitemid 34952754)
30. Mistry N, Cranmer SL, Yuan Y, et al. Cytoskeletal regulation of the platelet glycoprotein Ib/V/IX-von willebrand factor interaction. Blood 2000; 96: 3480-3489.
31. Lu Q, Clemetson JM, Clemetson KJ. Translocation of GPIb and Fc receptor gamma-chain to cytoskeleton in mucetin-activated platelets. J Thromb Haemost 2005; 3: 2065-2076. (Pubitemid 43086065)
32. Navdaev A, Clemetson KJ. Glycoprotein Ib cross-linking/ligation on echicetincoated surfaces or echicetin-IgMkappa in stirred suspension activates platelets by cytoskeleton modulated calcium release. J Biol Chem 2002; 277: 45928-45934. (Pubitemid 35417575)
33. Shrivastava M. The platelet storage lesion. Transfus Apher Sci 2009; 41: 105-113.
34. Cauwenberghs N, Vanhoorelbeke K, Vauterin S et al. Epitope mapping of inhibitory antibodies against platelet glycoprotein Ibalpha reveals interaction between the leucine-rich repeat N-terminal and C-terminal flanking domains of glycoprotein Ibalpha. Blood 2001; 98: 652-660.