Synthesis, cytotoxicity and antileishmanial activity of some N-(2-(indol-3-yl)ethyl)-7-chloroquinolin-4-amines

Chemical Biology and Drug Design

Volumn 75, Issue 6, 2010, Pages 628-631

  Coimbra, Elaine S ^a   Carvalhaes, Rafael ^a   Grazul, Richard M ^a   MacHado, Patricia A ^a   De Souza, Marcos V N ^b   Da Silva, Adilson D ^a  

^a FEDERAL UNIVERSITY OF JUIZ DE FORA   (Brazil)

^b INSTITUTO OSWALDO CRUZ   (Brazil)

Author keywords

4,7 dichloroquinoline; 7 chloroquinolin 4 amines; Leishmania; N (2 (indol 3 yl)ethyl) 7 chloroquinolin 4 amines; Tryptamine; Tryptophan

Indexed keywords

2 (7 CHLOROQUINOLIN 4 YLAMINO) 3 (1H INDOL 3 YL)PROPANOIC ACID; ANTIFLAGELLATE AGENT; ANTILEISHMANIAL AGENT; METHYL 2 (7 CHLOROQUINOLIN 4 YLAMINO) 3 (1H INDOL 3 YL)PROPANOATE; N (2 (1H INDOL 3 YL)ETHYL) 7 CHLOROQUINOLIN 4 AMINE; N [2 (INDOL 3 YL)ETHYL] 7 CHLOROQUINOLIN 4 AMINE DERIVATIVE; TRYPTAMINE; TRYPTOPHAN; UNCLASSIFIED DRUG;

ANIMAL CELL; ANTIPROTOZOAL ACTIVITY; ARTICLE; CELL STRAIN KB; CONTROLLED STUDY; DRUG CYTOTOXICITY; DRUG SCREENING; DRUG STRUCTURE; DRUG SYNTHESIS; HUMAN; HUMAN CELL; HYDROLYSIS KINETICS; IN VITRO STUDY; LEISHMANIA; LEISHMANIA BRAZILIENSIS; LEISHMANIA CHAGASI; LEISHMANIA MAJOR; NONHUMAN; PRIORITY JOURNAL; VERO CELL;

AMINOQUINOLINES; ANIMALS; ANTIPROTOZOAL AGENTS; CERCOPITHECUS AETHIOPS; HYDROLYSIS; LEISHMANIA; QUINOLINES; TRYPTOPHAN; VERO CELLS;

EID: 77951968641     PISSN: 17470277     EISSN: 17470285     Source Type: Journal    
DOI: 10.1111/j.1747-0285.2010.00962.x     Document Type: Article

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