메뉴 건너뛰기




Volumn 75, Issue 6, 2010, Pages 551-562

Structure and activity of CPNGRC: A modified CD13/APN peptidic homing motif

Author keywords

Aminopeptidase; Ligand; NMR; Peptide; Tumor

Indexed keywords

ANTINEOPLASTIC AGENT; CYSTEINYLASPARAGINYLGLYCYLARGINYLCYSTEINE; CYSTEINYLPROLYLASPARAGINYLGLYCYLARGINYLCYSTEINE; MICROSOMAL AMINOPEPTIDASE; PROLINE; PROTEIN INHIBITOR; UNCLASSIFIED DRUG;

EID: 77951957141     PISSN: 17470277     EISSN: 17470285     Source Type: Journal    
DOI: 10.1111/j.1747-0285.2010.00974.x     Document Type: Article
Times cited : (17)

References (40)
  • 1
    • 0032535999 scopus 로고    scopus 로고
    • Cancer treatment by targeted drug delivery to tumor vasculature in a mouse model
    • DOI 10.1126/science.279.5349.377
    • Arap W., Pasqualini R., Ruoslahti E. (1998) Cancer treatment by targeted drug delivery to tumor vasculature in a mouse model. Science 279 : 377 380. (Pubitemid 28063372)
    • (1998) Science , vol.279 , Issue.5349 , pp. 377-380
    • Arap, W.1    Pasqualini, R.2    Ruoslahti, E.3
  • 3
    • 27744555535 scopus 로고    scopus 로고
    • Aminopeptidase N/CD13 targeting fluorescent probes: Synthesis and application to tumor cell imaging
    • DOI 10.1016/j.peptides.2005.03.049, PII S0196978105001609
    • Zhang Z., Harada H., Tanabe K., Hatta H., Hiraoka M., Nishimoto S. (2005) Aminopeptidase N/CD13 targeting fluorescent probes: synthesis and application to tumor cell imaging. Peptides 26 : 2182 2187. (Pubitemid 41584082)
    • (2005) Peptides , vol.26 , Issue.11 , pp. 2182-2187
    • Zhang, Z.1    Harada, H.2    Tanabe, K.3    Hatta, H.4    Hiraoka, M.5    Nishimoto, S.-I.6
  • 5
    • 14944353793 scopus 로고    scopus 로고
    • Tumor vascular targeting with tumor necrosis factor α and chemotherapeutic drugs
    • DOI 10.1196/annals.1322.011
    • Corti A., Ponzoni M. (2004) Tumor vascular targeting with tumor necrosis factor alpha and chemotherapeutic drugs. Ann N Y Acad Sci 1028 : 104 112. (Pubitemid 40361814)
    • (2004) Annals of the New York Academy of Sciences , vol.1028 , pp. 104-112
    • Corti, A.1    Ponzoni, M.2
  • 6
    • 0033764170 scopus 로고    scopus 로고
    • Enhancement of tumor necrosis factor alpha antitumor immunotherapeutic properties by targeted delivery to aminopeptidase N (CD13)
    • Curnis F., Sacchi A., Borgna L., Magni F., Gasparri A., Corti A. (2000) Enhancement of tumor necrosis factor alpha antitumor immunotherapeutic properties by targeted delivery to aminopeptidase N (CD13). Nat Biotechnol 18 : 1185 1190.
    • (2000) Nat Biotechnol , vol.18 , pp. 1185-1190
    • Curnis, F.1    Sacchi, A.2    Borgna, L.3    Magni, F.4    Gasparri, A.5    Corti, A.6
  • 8
    • 13844292521 scopus 로고    scopus 로고
    • Tumor-specific gene delivery mediated by a novel peptide- polyethylenimine- DNA polyplex targeting aminopeptidase N/CD13
    • DOI 10.1089/hum.2005.16.57
    • Moffatt S., Wiehle S., Cristiano R.J. (2005) Tumor-specific gene delivery mediated by a novel peptide-polyethylenimine-DNA polyplex targeting aminopeptidase N/CD13. Hum Gene Ther 16 : 57 67. (Pubitemid 40250332)
    • (2005) Human Gene Therapy , vol.16 , Issue.1 , pp. 57-67
    • Moffatt, S.1    Wiehle, S.2    Cristiano, R.J.3
  • 12
    • 0027267959 scopus 로고
    • Selection of peptides binding to the alpha 5 beta 1 integrin from phage display library
    • Koivunen E., Gay D.A., Ruoslahti E. (1993) Selection of peptides binding to the alpha 5 beta 1 integrin from phage display library. J Biol Chem 268 : 20205 20210.
    • (1993) J Biol Chem , vol.268 , pp. 20205-20210
    • Koivunen, E.1    Gay, D.A.2    Ruoslahti, E.3
  • 13
    • 0027976103 scopus 로고
    • Isolation of a highly specific ligand for the alpha 5 beta 1 integrin from a phage display library
    • Koivunen E., Wang B., Ruoslahti E. (1994) Isolation of a highly specific ligand for the alpha 5 beta 1 integrin from a phage display library. J Cell Biol 124 : 373 380.
    • (1994) J Cell Biol , vol.124 , pp. 373-380
    • Koivunen, E.1    Wang, B.2    Ruoslahti, E.3
  • 15
    • 50349095214 scopus 로고    scopus 로고
    • Structural basis for the interaction of isoDGR with the RGD-binding site of alphavbeta3 integrin
    • Spitaleri A., Mari S., Curnis F., Traversari C., Longhi R., Bordignon C. et al. (2008) Structural basis for the interaction of isoDGR with the RGD-binding site of alphavbeta3 integrin. J Biol Chem 283 : 19757 19768.
    • (2008) J Biol Chem , vol.283 , pp. 19757-19768
    • Spitaleri, A.1    Mari, S.2    Curnis, F.3    Traversari, C.4    Longhi, R.5    Bordignon, C.6
  • 16
    • 67149122416 scopus 로고    scopus 로고
    • NGR and isoDGR are separate moieties binding to different receptors
    • author reply 7
    • Rizzardi G.P., Bordignon C. (2009) NGR and isoDGR are separate moieties binding to different receptors. Blood 113 : 5366, author reply 7.
    • (2009) Blood , vol.113 , pp. 5366
    • Rizzardi, G.P.1    Bordignon, C.2
  • 17
    • 66549114936 scopus 로고    scopus 로고
    • Infarction of tumor vessels by NGR-peptide-directed targeting of tissue factor: Experimental results and first-in-man experience
    • Bieker R., Kessler T., Schwoppe C., Padro T., Persigehl T., Bremer C. et al. (2009) Infarction of tumor vessels by NGR-peptide-directed targeting of tissue factor: experimental results and first-in-man experience. Blood 113 : 5019 5027.
    • (2009) Blood , vol.113 , pp. 5019-5027
    • Bieker, R.1    Kessler, T.2    Schwoppe, C.3    Padro, T.4    Persigehl, T.5    Bremer, C.6
  • 18
    • 0036468937 scopus 로고    scopus 로고
    • Differential binding of drugs containing the NGR motif to CD13 isoforms in tumor vessels, epithelia, and myeloid cells
    • Curnis F., Arrigoni G., Sacchi A., Fischetti L., Arap W., Pasqualini R. et al. (2002) Differential binding of drugs containing the NGR motif to CD13 isoforms in tumor vessels, epithelia, and myeloid cells. Cancer Res 62 : 867 874. (Pubitemid 34126966)
    • (2002) Cancer Research , vol.62 , Issue.3 , pp. 867-874
    • Curnis, F.1    Arrigoni, G.2    Sacchi, A.3    Fischetti, L.4    Arap, W.5    Pasqualini, R.6    Corti, A.7
  • 19
    • 0347626098 scopus 로고    scopus 로고
    • Biological significance of aminopeptidase N/CD13 in thyroid carcinomas
    • Kehlen A., Lendeckel U., Dralle H., Langner J., Hoang-Vu C. (2003) Biological significance of aminopeptidase N/CD13 in thyroid carcinomas. Cancer Res 63 : 8500 8506. (Pubitemid 37549507)
    • (2003) Cancer Research , vol.63 , Issue.23 , pp. 8500-8506
    • Kehlen, A.1    Lendeckel, U.2    Dralle, H.3    Langner, J.4    Hoang-Vu, C.5
  • 20
    • 0035130820 scopus 로고    scopus 로고
    • Novel, aberrantly truncated isoform of serum CD13 in a family with high serum aminopeptidase N (CD13) activity
    • Kawai M., Hara Y., Miyazato I., Hosaki S. (2001) Novel, aberrantly truncated isoform of serum CD13 in a family with high serum aminopeptidase N (CD13) activity. Clin Chem 47 : 223 230. (Pubitemid 32142920)
    • (2001) Clinical Chemistry , vol.47 , Issue.2 , pp. 223-230
    • Kawai, M.1    Hara, Y.2    Miyazato, I.3    Hosaki, S.4
  • 21
    • 0032049478 scopus 로고    scopus 로고
    • Aminopeptidase N in sera of healthy subjects is a different N-terminal processed derivative from the one obtained from maternal serum
    • DOI 10.1006/mgme.1998.2676
    • Watanabe Y., Ito K., Iwaki-Egawa S., Yamaguchi R., Fujimoto Y. (1998) Aminopeptidase N in sera of healthy subjects is a different N-terminal processed derivative from the one obtained from maternal serum. Mol Genet Metab 63 : 289 294. (Pubitemid 28455906)
    • (1998) Molecular Genetics and Metabolism , vol.63 , Issue.4 , pp. 289-294
    • Watanabe, Y.1    Ito, K.2    Iwaki-Egawa, S.3    Yamaguchi, R.4    Fujimoto, Y.5
  • 22
    • 0021868687 scopus 로고
    • Vascular, plasma membrane aminopeptidase M. Metabolism of vasoactive peptides
    • Palmieri F.E., Petrelli J.J., Ward P.E. (1985) Vascular, plasma membrane aminopeptidase M. Metabolism of vasoactive peptides. Biochem Pharmacol 34 : 2309 2317.
    • (1985) Biochem Pharmacol , vol.34 , pp. 2309-2317
    • Palmieri, F.E.1    Petrelli, J.J.2    Ward, P.E.3
  • 24
    • 0014091358 scopus 로고
    • Leucine aminopeptidase (arylamidase) activity in the serum. Determination using leucine-p-nitroanilide as substrate
    • Willig F., Greiner I., Stork H., Schmidt F.H. (1967) [Leucine aminopeptidase (arylamidase) activity in the serum. Determination using leucine-p-nitroanilide as substrate]. Klin Wochenschr 45 : 474 481.
    • (1967) Klin Wochenschr , vol.45 , pp. 474-481
    • Willig, F.1    Greiner, I.2    Stork, H.3    Schmidt, F.H.4
  • 25
    • 0014969625 scopus 로고
    • Aminopeptidases in ovarian carcinomas in relation to clinical and pathological findings. A biochemical and histochemical study
    • Pfleiderer A. Jr., Kidess E., Jung G. (1970) [Aminopeptidases in ovarian carcinomas in relation to clinical and pathological findings. A biochemical and histochemical study]. Arch Gynakol 209 : 121 135.
    • (1970) Arch Gynakol , vol.209 , pp. 121-135
    • Pfleiderer Jr., A.1    Kidess, E.2    Jung, G.3
  • 26
    • 0020841758 scopus 로고
    • Proteolysis in eucaryotic cells: Aminopeptidases and dipeptidyl aminopeptidases of yeast revisited
    • Achstetter T., Ehmann C., Wolf D.H. (1983) Proteolysis in eucaryotic cells: aminopeptidases and dipeptidyl aminopeptidases of yeast revisited. Arch Biochem Biophys 226 : 292 305.
    • (1983) Arch Biochem Biophys , vol.226 , pp. 292-305
    • Achstetter, T.1    Ehmann, C.2    Wolf, D.H.3
  • 27
    • 0026951903 scopus 로고
    • Gradient-tailored excitation for single-quantum NMR spectroscopy of aqueous solutions
    • Piotto M., Saudek V., Sklenar V. (1992) Gradient-tailored excitation for single-quantum NMR spectroscopy of aqueous solutions. J Biomol NMR 2 : 661 665.
    • (1992) J Biomol NMR , vol.2 , pp. 661-665
    • Piotto, M.1    Saudek, V.2    Sklenar, V.3
  • 29
    • 5144233105 scopus 로고
    • Mlev-17-Based two-dimensional homonuclear magnetization transfer spectroscopy
    • Bax A., Davies D.G. (1985) Mlev-17-Based Two-Dimensional Homonuclear Magnetization Transfer Spectroscopy. J Magn Reson 65 : 355 360.
    • (1985) J Magn Reson , vol.65 , pp. 355-360
    • Bax, A.1    Davies, D.G.2
  • 30
    • 0011491177 scopus 로고
    • Structure determination of a tetrasaccharide: Transient nuclear Overhauser effects in the rotating frame
    • Bothner-By A.A., Stephens R.L., Lee J., Warren C.D., Jeanloz R.W. (1984) Structure determination of a tetrasaccharide: transient nuclear Overhauser effects in the rotating frame. J Am Chem Soc 106 : 811 813.
    • (1984) J Am Chem Soc , vol.106 , pp. 811-813
    • Bothner-By, A.A.1    Stephens, R.L.2    Lee, J.3    Warren, C.D.4    Jeanloz, R.W.5
  • 32
    • 0035742323 scopus 로고    scopus 로고
    • Internal coordinates for molecular dynamics and minimization in structure determination and refinement
    • Schwieters C.D., Clore G.M. (2001) Internal coordinates for molecular dynamics and minimization in structure determination and refinement. J Magn Reson 152 : 288 302.
    • (2001) J Magn Reson , vol.152 , pp. 288-302
    • Schwieters, C.D.1    Clore, G.M.2
  • 35
    • 0022400582 scopus 로고
    • The slow, tight binding of bestatin and amastatin to aminopeptidases
    • Wilkes S.H., Prescott J.M. (1985) The slow, tight binding of bestatin and amastatin to aminopeptidases. J Biol Chem 260 : 13154 13162.
    • (1985) J Biol Chem , vol.260 , pp. 13154-13162
    • Wilkes, S.H.1    Prescott, J.M.2
  • 36
    • 0022854871 scopus 로고
    • Anchoring and biosynthesis of stalked brush border membrane proteins: Glycosidases and peptidases of enterocytes and renal tubuli
    • Semenza G. (1986) Anchoring and biosynthesis of stalked brush border membrane proteins: glycosidases and peptidases of enterocytes and renal tubuli. Annu Rev Cell Biol 2 : 255 313.
    • (1986) Annu Rev Cell Biol , vol.2 , pp. 255-313
    • Semenza, G.1
  • 37
    • 0020007911 scopus 로고
    • Topology of microvillar membrane hydrolases of kidney and intestine
    • Kenny A.J., Maroux S. (1982) Topology of microvillar membrane hydrolases of kidney and intestine. Physiol Rev 62 : 91 128.
    • (1982) Physiol Rev , vol.62 , pp. 91-128
    • Kenny, A.J.1    Maroux, S.2
  • 38
    • 0024312336 scopus 로고
    • Conformational change of rabbit aminopeptidase N into enterocyte plasma membrane domains analyzed by flow cytometry fluorescence energy transfer
    • Gorvel J.P., Mishal Z., Liegey F., Rigal A., Maroux S. (1989) Conformational change of rabbit aminopeptidase N into enterocyte plasma membrane domains analyzed by flow cytometry fluorescence energy transfer. J Cell Biol 108 : 2193 2200. (Pubitemid 19168912)
    • (1989) Journal of Cell Biology , vol.108 , Issue.6 , pp. 2193-2200
    • Gorvel, J.-P.1    Mishal, Z.2    Liegey, F.3    Rigal, A.4    Maroux, S.5
  • 40
    • 0000243829 scopus 로고
    • PROCHECK: A program to check the stereochemical quality of protein structures
    • Laskowski R.A., MacArthur M.W., Moss D.S., Thornton J.M. (1993) PROCHECK: a Program to Check the Stereochemical Quality of Protein Structures. J Appl Crystallogr 26 : 283 291.
    • (1993) J Appl Crystallogr , vol.26 , pp. 283-291
    • Laskowski, R.A.1    MacArthur, M.W.2    Moss, D.S.3    Thornton, J.M.4


* 이 정보는 Elsevier사의 SCOPUS DB에서 KISTI가 분석하여 추출한 것입니다.