메뉴 건너뛰기




Volumn 117, Issue 3, 2010, Pages 429-439

Translational research in the Gynecologic Oncology Group: Evaluation of ovarian cancer markers, profiles, and novel therapies

Author keywords

Markers; Novel therapies; Ovarian cancer; Profiles; Translational research; Tumor biology

Indexed keywords

BEVACIZUMAB; BLEOMYCIN; BORTEZOMIB; BRCA1 PROTEIN; CAPECITABINE; CARBOPLATIN; CISPLATIN; CYCLIN E; CYCLOPHOSPHAMIDE; DACTINOMYCIN; DASATINIB; DOXORUBICIN; ENZASTAURIN; GEFITINIB; GEMCITABINE; IMATINIB; LAPATINIB; MOTESANIB; PACLITAXEL; PACLITAXEL POLIGLUMEX; PLACEBO; PLATINUM DERIVATIVE; SORAFENIB; TAMOXIFEN; TAXANE DERIVATIVE; TEMSIROLIMUS; THALIDOMIDE; TRASTUZUMAB; UNINDEXED DRUG; VINCRISTINE;

EID: 77951938162     PISSN: 00908258     EISSN: 10956859     Source Type: Journal    
DOI: 10.1016/j.ygyno.2010.01.048     Document Type: Article
Times cited : (31)

References (59)
  • 1
    • 0030054309 scopus 로고    scopus 로고
    • Cyclophosphamide and cisplatin compared with paclitaxel and cisplatin in patients with stage III and stage IV epithelial ovarian cancer
    • McGuire W.P., Hoskins W.J., Brady M.F., Kucera P.R., Partridge E.E., Look K.Y., et al. Cyclophosphamide and cisplatin compared with paclitaxel and cisplatin in patients with stage III and stage IV epithelial ovarian cancer. N Engl J Med 334 1 (1996) 1-6
    • (1996) N Engl J Med , vol.334 , Issue.1 , pp. 1-6
    • McGuire, W.P.1    Hoskins, W.J.2    Brady, M.F.3    Kucera, P.R.4    Partridge, E.E.5    Look, K.Y.6
  • 2
    • 0037444379 scopus 로고    scopus 로고
    • Cyclin E expression is a significant predictor of survival in advanced, suboptimally debulked ovarian epithelial cancers: a Gynecologic Oncology Group study
    • Farley J., Smith L.M., Darcy K.M., Sobel E., O'Connor D., Henderson B., et al. Cyclin E expression is a significant predictor of survival in advanced, suboptimally debulked ovarian epithelial cancers: a Gynecologic Oncology Group study. Cancer Res 63 (2003) 1235-1241
    • (2003) Cancer Res , vol.63 , pp. 1235-1241
    • Farley, J.1    Smith, L.M.2    Darcy, K.M.3    Sobel, E.4    O'Connor, D.5    Henderson, B.6
  • 3
    • 56749098120 scopus 로고    scopus 로고
    • Associations between p53 overexpression and multiple measures of clinical outcome in high-risk, early stage and suboptimally-resected, advanced stage epithelial ovarian cancers: a Gynecologic Oncology Group study
    • Darcy K.M., Brady W.E., McBroom J.W., Bell J.G., Young R.C., McGuire W.P., et al. Associations between p53 overexpression and multiple measures of clinical outcome in high-risk, early stage and suboptimally-resected, advanced stage epithelial ovarian cancers: a Gynecologic Oncology Group study. Gynecol Oncol 111 3 (2008) 487-495
    • (2008) Gynecol Oncol , vol.111 , Issue.3 , pp. 487-495
    • Darcy, K.M.1    Brady, W.E.2    McBroom, J.W.3    Bell, J.G.4    Young, R.C.5    McGuire, W.P.6
  • 4
    • 67349095676 scopus 로고    scopus 로고
    • Associations between ERBB2 amplification and progression-free survival and overall survival in advanced stage, suboptimally-resected epithelial ovarian cancers: a Gynecologic Oncology Group study
    • Farley J., Fuchiuji S., Darcy K.M., Tian C., Hoskins W.J., McGuire W.P., et al. Associations between ERBB2 amplification and progression-free survival and overall survival in advanced stage, suboptimally-resected epithelial ovarian cancers: a Gynecologic Oncology Group study. Gynecol Oncol 113 3 (2009) 341-347
    • (2009) Gynecol Oncol , vol.113 , Issue.3 , pp. 341-347
    • Farley, J.1    Fuchiuji, S.2    Darcy, K.M.3    Tian, C.4    Hoskins, W.J.5    McGuire, W.P.6
  • 5
    • 67651225134 scopus 로고    scopus 로고
    • Prognostic relevance of c-MYC gene amplification and polysomy for chromosome 8 in suboptimally-resected, advanced stage epithelial ovarian cancers: a Gynecologic Oncology Group study
    • Darcy K.M., Brady W.E., Blancato J.K., Dickson R.B., Hoskins W.J., McGuire W.P., et al. Prognostic relevance of c-MYC gene amplification and polysomy for chromosome 8 in suboptimally-resected, advanced stage epithelial ovarian cancers: a Gynecologic Oncology Group study. Gynecol Oncol 114 3 (2009) 472-479
    • (2009) Gynecol Oncol , vol.114 , Issue.3 , pp. 472-479
    • Darcy, K.M.1    Brady, W.E.2    Blancato, J.K.3    Dickson, R.B.4    Hoskins, W.J.5    McGuire, W.P.6
  • 6
    • 0035865144 scopus 로고    scopus 로고
    • Phase III trial of standard-dose intravenous cisplatin plus paclitaxel versus moderately high-dose carboplatin followed by intravenous paclitaxel and intraperitoneal cisplatin in small-volume stage III ovarian carcinoma: an intergroup study of the Gynecologic Oncology Group, Southwestern Oncology Group, and Eastern Cooperative Oncology Group
    • Markman M., Bundy B.N., Alberts D.S., Fowler J.M., Clarke-Pearson D.L., Carson L.F., et al. Phase III trial of standard-dose intravenous cisplatin plus paclitaxel versus moderately high-dose carboplatin followed by intravenous paclitaxel and intraperitoneal cisplatin in small-volume stage III ovarian carcinoma: an intergroup study of the Gynecologic Oncology Group, Southwestern Oncology Group, and Eastern Cooperative Oncology Group. J Clin Oncol 19 4 (2001) 1001-1007
    • (2001) J Clin Oncol , vol.19 , Issue.4 , pp. 1001-1007
    • Markman, M.1    Bundy, B.N.2    Alberts, D.S.3    Fowler, J.M.4    Clarke-Pearson, D.L.5    Carson, L.F.6
  • 7
    • 0033986363 scopus 로고    scopus 로고
    • Phase III randomized study of cisplatin versus paclitaxel versus cisplatin and paclitaxel in patients with suboptimal stage III or IV ovarian cancer: a Gynecologic Oncology Group Study
    • Muggia F.M., Braly P.S., Brady M.F., Sutton G., Niemann T.H., Lentz S.L., et al. Phase III randomized study of cisplatin versus paclitaxel versus cisplatin and paclitaxel in patients with suboptimal stage III or IV ovarian cancer: a Gynecologic Oncology Group Study. J Clin Oncol 18 1 (2000) 106-115
    • (2000) J Clin Oncol , vol.18 , Issue.1 , pp. 106-115
    • Muggia, F.M.1    Braly, P.S.2    Brady, M.F.3    Sutton, G.4    Niemann, T.H.5    Lentz, S.L.6
  • 8
    • 0142087616 scopus 로고    scopus 로고
    • Prognostic significance of p53 mutation and p53 overexpression in advanced epithelial ovarian cancer: a Gynecologic Oncology Group study
    • Havrilesky L., Darcy K.M., Hamdan H., Priore R.L., Leon J., Bell J., and Berchuck A. Prognostic significance of p53 mutation and p53 overexpression in advanced epithelial ovarian cancer: a Gynecologic Oncology Group study. J Clin Oncol 21 20 (2003) 3814-3825
    • (2003) J Clin Oncol , vol.21 , Issue.20 , pp. 3814-3825
    • Havrilesky, L.1    Darcy, K.M.2    Hamdan, H.3    Priore, R.L.4    Leon, J.5    Bell, J.6    Berchuck, A.7
  • 9
    • 33646718965 scopus 로고    scopus 로고
    • Maspin expression in epithelial ovarian cancer and associations with poor prognosis: a Gynecologic Oncology Group study
    • Secord A.A., Lee P.S., Darcy K.M., Havrilesky L.J., Grace L.A., Marks J.R., and Berchuck A. Maspin expression in epithelial ovarian cancer and associations with poor prognosis: a Gynecologic Oncology Group study. Gynecol Oncol 101 3 (2006) 390-397
    • (2006) Gynecol Oncol , vol.101 , Issue.3 , pp. 390-397
    • Secord, A.A.1    Lee, P.S.2    Darcy, K.M.3    Havrilesky, L.J.4    Grace, L.A.5    Marks, J.R.6    Berchuck, A.7
  • 10
    • 77951939337 scopus 로고    scopus 로고
    • The role of methylation in the regulation of angiogenic inhibitors in advanced epithelial ovarian cancer: a Gynecologic Oncology Group Study
    • Secord A.A., Lee P.S., Jewell E., Havrilesky L., Grace L., Murphy Berchuck A., et al. The role of methylation in the regulation of angiogenic inhibitors in advanced epithelial ovarian cancer: a Gynecologic Oncology Group Study. Gynecol Oncol 101 (2006) S84
    • (2006) Gynecol Oncol , vol.101
    • Secord, A.A.1    Lee, P.S.2    Jewell, E.3    Havrilesky, L.4    Grace, L.5    Murphy Berchuck, A.6
  • 11
    • 34250304711 scopus 로고    scopus 로고
    • Co-expression of angiogenic markers and associations with prognosis in advanced epithelial ovarian cancer: a Gynecologic Oncology Group study
    • Secord A.A., Darcy K.M., Hutson A., Lee P.S., Havrilesky L.J., Grace L.A., et al. Co-expression of angiogenic markers and associations with prognosis in advanced epithelial ovarian cancer: a Gynecologic Oncology Group study. Gynecol Oncol 106 1 (2007) 221-232
    • (2007) Gynecol Oncol , vol.106 , Issue.1 , pp. 221-232
    • Secord, A.A.1    Darcy, K.M.2    Hutson, A.3    Lee, P.S.4    Havrilesky, L.J.5    Grace, L.A.6
  • 12
    • 60449117723 scopus 로고    scopus 로고
    • Independent prognostic relevance of microvessel density in advanced epithelial ovarian cancer and associations between CD31, CD105, p53 status and angiogenic marker expression: a Gynecologic Oncology Group study
    • Rubatt J.M., Darcy K.M., Hutson A., Bean S., Havrilesky L.J., Grace L.A., et al. Independent prognostic relevance of microvessel density in advanced epithelial ovarian cancer and associations between CD31, CD105, p53 status and angiogenic marker expression: a Gynecologic Oncology Group study. Gynecol Oncol 112 3 (2009) 469-474
    • (2009) Gynecol Oncol , vol.112 , Issue.3 , pp. 469-474
    • Rubatt, J.M.1    Darcy, K.M.2    Hutson, A.3    Bean, S.4    Havrilesky, L.J.5    Grace, L.A.6
  • 13
    • 77951938630 scopus 로고    scopus 로고
    • Loss of expression of the p16 tumor suppressor gene is more frequent in advanced ovarian cancers lacking p53 mutations: a Gynecologic Oncology Group study
    • Havrilesky L., Alvarez A., Whitaker R., Marks J., and Berchuck A. Loss of expression of the p16 tumor suppressor gene is more frequent in advanced ovarian cancers lacking p53 mutations: a Gynecologic Oncology Group study. Gynecol Oncol 80 2 (2001) 283
    • (2001) Gynecol Oncol , vol.80 , Issue.2 , pp. 283
    • Havrilesky, L.1    Alvarez, A.2    Whitaker, R.3    Marks, J.4    Berchuck, A.5
  • 14
    • 77951939581 scopus 로고    scopus 로고
    • Correlations between cell cycle regulatory genes and relationship to ovarian cancer prognosis: a Gynecologic Oncology Group study
    • Havrilesky L.J., Fleming N.D., Miner Z., Darcy K., Hutson A., Berchuck A., et al. Correlations between cell cycle regulatory genes and relationship to ovarian cancer prognosis: a Gynecologic Oncology Group study. Gynecol Oncol 104 (2007) S54
    • (2007) Gynecol Oncol , vol.104
    • Havrilesky, L.J.1    Fleming, N.D.2    Miner, Z.3    Darcy, K.4    Hutson, A.5    Berchuck, A.6
  • 15
    • 70350569893 scopus 로고    scopus 로고
    • Association between the N-terminally truncated (ΔN) p63α (ΔNp63α) isoform and debulking status, VEGF expression and progression-free survival in previously-untreated, advanced stage epithelial ovarian cancer: a Gynecologic Oncology Group study
    • Jewell E.L., Darcy K.M., Hutson A., Lee P.S., Havrilesky L.J., Grace L.A., et al. Association between the N-terminally truncated (ΔN) p63α (ΔNp63α) isoform and debulking status, VEGF expression and progression-free survival in previously-untreated, advanced stage epithelial ovarian cancer: a Gynecologic Oncology Group study. Gynecol Oncol 115 3 (2009) 424-429
    • (2009) Gynecol Oncol , vol.115 , Issue.3 , pp. 424-429
    • Jewell, E.L.1    Darcy, K.M.2    Hutson, A.3    Lee, P.S.4    Havrilesky, L.J.5    Grace, L.A.6
  • 16
    • 3042626420 scopus 로고    scopus 로고
    • Association between serum levels of soluble tumor necrosis factor receptors/CA 125 and disease progression in patients with epithelial ovarian malignancy: a Gynecologic Oncology Group study
    • Burger R.A., Darcy K.M., DiSaia P.J., Monk B.J., Grosen E.A., Gatanaga T., et al. Association between serum levels of soluble tumor necrosis factor receptors/CA 125 and disease progression in patients with epithelial ovarian malignancy: a Gynecologic Oncology Group study. Cancer 101 1 (2004) 106-115
    • (2004) Cancer , vol.101 , Issue.1 , pp. 106-115
    • Burger, R.A.1    Darcy, K.M.2    DiSaia, P.J.3    Monk, B.J.4    Grosen, E.A.5    Gatanaga, T.6
  • 17
    • 33748458411 scopus 로고    scopus 로고
    • Randomized phase III trial of three versus six cycles of adjuvant carboplatin and paclitaxel in early stage ovarian carcinoma: a Gynecologic Oncology Group study
    • Bell J., Brady M., Young R., Lage J., Walker J., Look K.Y., et al. Randomized phase III trial of three versus six cycles of adjuvant carboplatin and paclitaxel in early stage ovarian carcinoma: a Gynecologic Oncology Group study. Gynecol Oncol 102 3 (2006) 432-439
    • (2006) Gynecol Oncol , vol.102 , Issue.3 , pp. 432-439
    • Bell, J.1    Brady, M.2    Young, R.3    Lage, J.4    Walker, J.5    Look, K.Y.6
  • 18
    • 77951938350 scopus 로고    scopus 로고
    • Alterations in cyclin E and p27 in early epithelial ovarian cancer: a Gynecologic Oncology Group study
    • Farley J.H., Smith L., Darcy K.M., Tian C., Sobel E., and Birrer M.J. Alterations in cyclin E and p27 in early epithelial ovarian cancer: a Gynecologic Oncology Group study. Gynecol Oncol 84 3 (2002) 499
    • (2002) Gynecol Oncol , vol.84 , Issue.3 , pp. 499
    • Farley, J.H.1    Smith, L.2    Darcy, K.M.3    Tian, C.4    Sobel, E.5    Birrer, M.J.6
  • 19
    • 77951938089 scopus 로고    scopus 로고
    • Angiogenic marker alteration in high-risk stage I or II epithelial ovarian cancer
    • Garg R., Garcia R.L., Brady M.F., Goff B.A., and Paley P. Angiogenic marker alteration in high-risk stage I or II epithelial ovarian cancer. Gynecol Oncol 104 3 (2007) S43
    • (2007) Gynecol Oncol , vol.104 , Issue.3
    • Garg, R.1    Garcia, R.L.2    Brady, M.F.3    Goff, B.A.4    Paley, P.5
  • 20
    • 0141688377 scopus 로고    scopus 로고
    • Phase III trial of carboplatin and paclitaxel compared with cisplatin and paclitaxel in patients with optimally resected stage III ovarian cancer: a Gynecologic Oncology Group study
    • Ozol R.F., Bundy B.N., Greer B.E., Fowler J.M., Clarke-Pearson, Burger R.A., et al. Phase III trial of carboplatin and paclitaxel compared with cisplatin and paclitaxel in patients with optimally resected stage III ovarian cancer: a Gynecologic Oncology Group study. J Clin Oncol 21 17 (2003) 3194-3200
    • (2003) J Clin Oncol , vol.21 , Issue.17 , pp. 3194-3200
    • Ozol, R.F.1    Bundy, B.N.2    Greer, B.E.3    Fowler, J.M.4    Clarke-Pearson5    Burger, R.A.6
  • 21
    • 34249285904 scopus 로고    scopus 로고
    • A Gynecologic Oncology Group study of platinum-DNA adducts and excision repair cross-complementation group 1 expression in optimal, stage III epithelial ovarian cancer treated with platinum-taxane chemotherapy
    • Darcy K.M., Tian C., and Reed E. A Gynecologic Oncology Group study of platinum-DNA adducts and excision repair cross-complementation group 1 expression in optimal, stage III epithelial ovarian cancer treated with platinum-taxane chemotherapy. Cancer Res 67 9 (2007) 4474-4481
    • (2007) Cancer Res , vol.67 , Issue.9 , pp. 4474-4481
    • Darcy, K.M.1    Tian, C.2    Reed, E.3
  • 22
    • 77951938721 scopus 로고    scopus 로고
    • A Gynecologic Oncology Group study of frequent copy number aberrations in DNA repair genes and other genomic regions in stage I serous ovarian cancers
    • ASCO Abstract #e16504
    • Pejovic T., Gaile D.P., Darcy K.M., Liu S., Shepherd L., Rodgers W.H., et al. A Gynecologic Oncology Group study of frequent copy number aberrations in DNA repair genes and other genomic regions in stage I serous ovarian cancers. J Clin Oncol 27 (2009) ASCO Abstract #e16504
    • (2009) J Clin Oncol , vol.27
    • Pejovic, T.1    Gaile, D.P.2    Darcy, K.M.3    Liu, S.4    Shepherd, L.5    Rodgers, W.H.6
  • 23
    • 77951938699 scopus 로고    scopus 로고
    • iGenomic Viewer, a Gynecologic Oncology Group software library for the creation of highly customizable, portable, interactive, and linked visualizations of high throughput genomic data
    • ASCO Abstract # e16544
    • Gaile D.P., Shepherd L., Liu S., Darcy K., Brady M., and Morrison C. iGenomic Viewer, a Gynecologic Oncology Group software library for the creation of highly customizable, portable, interactive, and linked visualizations of high throughput genomic data. J Clin Oncol 27 (2009) ASCO Abstract # e16544
    • (2009) J Clin Oncol , vol.27
    • Gaile, D.P.1    Shepherd, L.2    Liu, S.3    Darcy, K.4    Brady, M.5    Morrison, C.6
  • 25
    • 63049115790 scopus 로고    scopus 로고
    • Evaluation of new platinum-based treatment regimens in advanced-stage ovarian cancer: a phase III trial of the Gynecologic Cancer Intergroup
    • Bookman M., Brady M., McGuire W., Harper P., Alberts D., Friedlander M., et al. Evaluation of new platinum-based treatment regimens in advanced-stage ovarian cancer: a phase III trial of the Gynecologic Cancer Intergroup. J Clin Oncol 27 9 (2009) 1419-1425
    • (2009) J Clin Oncol , vol.27 , Issue.9 , pp. 1419-1425
    • Bookman, M.1    Brady, M.2    McGuire, W.3    Harper, P.4    Alberts, D.5    Friedlander, M.6
  • 26
    • 77951937997 scopus 로고    scopus 로고
    • The prognostic significance of germline BRCA1 mutations in epithelial ovarian cancer: a Gynecologic Oncology Group Study
    • Gallion H., Kryscio R., Clarke-Pearson D., DiSaia P., Fowler J., Mannel R., et al. The prognostic significance of germline BRCA1 mutations in epithelial ovarian cancer: a Gynecologic Oncology Group Study. Gynecol Oncol 88 2 (2003) 157
    • (2003) Gynecol Oncol , vol.88 , Issue.2 , pp. 157
    • Gallion, H.1    Kryscio, R.2    Clarke-Pearson, D.3    DiSaia, P.4    Fowler, J.5    Mannel, R.6
  • 28
    • 33645359491 scopus 로고    scopus 로고
    • BRCA1 expression in a large series of sporadic ovarian carcinomas: a Gynecologic Oncology Group study
    • Thrall M., Gallion H.H., Kryscio R., Kapali M., Armstrong D.K., and Deloia J.A. BRCA1 expression in a large series of sporadic ovarian carcinomas: a Gynecologic Oncology Group study. Int J Gynecol Cancer 16 Suppl. 1 (2006) 166-171
    • (2006) Int J Gynecol Cancer , vol.16 , Issue.SUPPL. 1 , pp. 166-171
    • Thrall, M.1    Gallion, H.H.2    Kryscio, R.3    Kapali, M.4    Armstrong, D.K.5    Deloia, J.A.6
  • 30
    • 49049118079 scopus 로고    scopus 로고
    • Relationship between ERCC1 polymorphisms and disease progression and survival in the Gynecologic Oncology Group phase III trial of intraperitoneal versus intravenous cisplatin and paclitaxel for stage III epithelial ovarian cancer
    • Krivak T.C., Darcy K.M., Tian C., Armstrong D., Baysal B.E., Gallion H., et al. Relationship between ERCC1 polymorphisms and disease progression and survival in the Gynecologic Oncology Group phase III trial of intraperitoneal versus intravenous cisplatin and paclitaxel for stage III epithelial ovarian cancer. J Clin Oncol 26 21 (2008) 3598-3606
    • (2008) J Clin Oncol , vol.26 , Issue.21 , pp. 3598-3606
    • Krivak, T.C.1    Darcy, K.M.2    Tian, C.3    Armstrong, D.4    Baysal, B.E.5    Gallion, H.6
  • 31
    • 77951938217 scopus 로고    scopus 로고
    • Relationship between ERCC1 polymorphism, disease progression and survival in GOG0182: a Gynecologic Oncology Group phase III trial of platinum-based chemotherapy in women with advanced stage epithelial ovarian or primary peritoneal cancer
    • Krivak T.C., Darcy K., Tian C., Bookman M.A., Baysal B.A., Gallion H., et al. Relationship between ERCC1 polymorphism, disease progression and survival in GOG0182: a Gynecologic Oncology Group phase III trial of platinum-based chemotherapy in women with advanced stage epithelial ovarian or primary peritoneal cancer. J Clin Oncol 26 15s (2008) 302s
    • (2008) J Clin Oncol , vol.26 , Issue.15 s
    • Krivak, T.C.1    Darcy, K.2    Tian, C.3    Bookman, M.A.4    Baysal, B.A.5    Gallion, H.6
  • 32
    • 77951937820 scopus 로고    scopus 로고
    • BRCA1/BRCA2 polymorphisms and prognosis in women with optimally-resected stage III epithelial ovarian cancer treated on GOG Protocol 172: a Gynecologic Oncology Group study
    • Krivak T.C., Tian C., DeLoia J.A., Darcy K.M., Armstrong D., Gallion H., et al. BRCA1/BRCA2 polymorphisms and prognosis in women with optimally-resected stage III epithelial ovarian cancer treated on GOG Protocol 172: a Gynecologic Oncology Group study. Gynecol Oncol 112 2 (2009) S9
    • (2009) Gynecol Oncol , vol.112 , Issue.2
    • Krivak, T.C.1    Tian, C.2    DeLoia, J.A.3    Darcy, K.M.4    Armstrong, D.5    Gallion, H.6
  • 33
    • 77951937581 scopus 로고    scopus 로고
    • A Gynecologic Oncology Group study of associations between polymorphisms in ABC transporter genes (ABCB1, ABCC2 and ABCG2) and outcome in advanced stage epithelial ovarian cancer treated with platinum and taxane chemotherapy
    • Darcy K.M., Tian C., Ambrosone C.B., Krivak T.C., Armstrong D., Bookman M.A., et al. A Gynecologic Oncology Group study of associations between polymorphisms in ABC transporter genes (ABCB1, ABCC2 and ABCG2) and outcome in advanced stage epithelial ovarian cancer treated with platinum and taxane chemotherapy. J Clin Oncol 27 15S (2009) s293
    • (2009) J Clin Oncol , vol.27 , Issue.15 S
    • Darcy, K.M.1    Tian, C.2    Ambrosone, C.B.3    Krivak, T.C.4    Armstrong, D.5    Bookman, M.A.6
  • 34
    • 13844298089 scopus 로고    scopus 로고
    • Phase II clinical trial of capecitabine in ovarian carcinoma recurrent 6-12 months after completion of primary chemotherapy, with exploratory TS, DPD, and TP correlates: a Gynecologic Oncology Group study
    • Garcia A.A., Blessing J.A., Lenz H.J., Darcy K.M., Mannel R.S., Miller D.S., et al. Phase II clinical trial of capecitabine in ovarian carcinoma recurrent 6-12 months after completion of primary chemotherapy, with exploratory TS, DPD, and TP correlates: a Gynecologic Oncology Group study. Gynecol Oncol 96 3 (2005) 810-811
    • (2005) Gynecol Oncol , vol.96 , Issue.3 , pp. 810-811
    • Garcia, A.A.1    Blessing, J.A.2    Lenz, H.J.3    Darcy, K.M.4    Mannel, R.S.5    Miller, D.S.6
  • 35
    • 70349754173 scopus 로고    scopus 로고
    • A phase II evaluation of bortezomib in the treatment of recurrent platinum-sensitive ovarian or primary peritoneal cancer: a Gynecologic Oncology Group study
    • Aghajanian C., Blessing J.A., Darcy K.M., Reid G., DeGeest K., Rubin S.C., et al. A phase II evaluation of bortezomib in the treatment of recurrent platinum-sensitive ovarian or primary peritoneal cancer: a Gynecologic Oncology Group study. Gynecol Oncol 115 2 (2009) 215-220
    • (2009) Gynecol Oncol , vol.115 , Issue.2 , pp. 215-220
    • Aghajanian, C.1    Blessing, J.A.2    Darcy, K.M.3    Reid, G.4    DeGeest, K.5    Rubin, S.C.6
  • 36
    • 39249085402 scopus 로고    scopus 로고
    • Phase II trial of cetuximab and carboplatin in relapsed platinum-sensitive ovarian or cancer and evaluation of epidermal growth factor receptor expression: a Gynecologic Oncology Group study
    • Secord A.A., Blessing J.A., Armstrong D.K., Rodgers W.H., Miner Z., Barnes M.N., et al. Phase II trial of cetuximab and carboplatin in relapsed platinum-sensitive ovarian or cancer and evaluation of epidermal growth factor receptor expression: a Gynecologic Oncology Group study. Gynecol Oncol 108 3 (2008) 493-499
    • (2008) Gynecol Oncol , vol.108 , Issue.3 , pp. 493-499
    • Secord, A.A.1    Blessing, J.A.2    Armstrong, D.K.3    Rodgers, W.H.4    Miner, Z.5    Barnes, M.N.6
  • 37
    • 0037440042 scopus 로고    scopus 로고
    • Evaluation of monoclonal humanized anti-HER2 antibody (Trastuzumab) in patients with recurrent or refractory ovarian or primary peritoneal carcinoma with overexpression of HER2: a phase II trial of the Gynecologic Oncology Group
    • Bookman M.A., Darcy K.M., Clarke-Pearson D., Boothby R.A., and Horowitz I.R. Evaluation of monoclonal humanized anti-HER2 antibody (Trastuzumab) in patients with recurrent or refractory ovarian or primary peritoneal carcinoma with overexpression of HER2: a phase II trial of the Gynecologic Oncology Group. J. Clin. Oncol 21 2 (2003) 283-290
    • (2003) J. Clin. Oncol , vol.21 , Issue.2 , pp. 283-290
    • Bookman, M.A.1    Darcy, K.M.2    Clarke-Pearson, D.3    Boothby, R.A.4    Horowitz, I.R.5
  • 38
    • 23044511620 scopus 로고    scopus 로고
    • Phase II study of gefitinib in patients with relapsed or persistent ovarian or primary peritoneal carcinoma and evaluation of epidermal growth factor receptor mutations and immunohistochemical expression: a Gynecologic Oncology Group study
    • Schilder R., Sill M., Chen X., Darcy K., DeCesare S., Lewandowski G., et al. Phase II study of gefitinib in patients with relapsed or persistent ovarian or primary peritoneal carcinoma and evaluation of epidermal growth factor receptor mutations and immunohistochemical expression: a Gynecologic Oncology Group study. Clin Cancer Res. 11 15 (2005) 5539-5548
    • (2005) Clin Cancer Res. , vol.11 , Issue.15 , pp. 5539-5548
    • Schilder, R.1    Sill, M.2    Chen, X.3    Darcy, K.4    DeCesare, S.5    Lewandowski, G.6
  • 39
    • 36849019301 scopus 로고    scopus 로고
    • Phase II trial of bevacizumab in persistent or recurrent epithelial ovarian cancer or primary peritoneal cancer: a Gynecologic Oncology Group Study
    • Burger R.A., Sill M.W., Monk B.J., Greer B.E., and Sorosky J.I. Phase II trial of bevacizumab in persistent or recurrent epithelial ovarian cancer or primary peritoneal cancer: a Gynecologic Oncology Group Study. J Clin Oncol 25 33 (2007) 5165-5171
    • (2007) J Clin Oncol , vol.25 , Issue.33 , pp. 5165-5171
    • Burger, R.A.1    Sill, M.W.2    Monk, B.J.3    Greer, B.E.4    Sorosky, J.I.5
  • 40
    • 70350712625 scopus 로고    scopus 로고
    • Relationship between angiogenic markers and clinicopathologic factors/outcome in GOG-170D, a phase II trial of bevacizumab (Bev) in recurrent or persistent epithelial ovarian cancer (EOC) and primary peritoneal cancer (PPC)
    • Han E.S., Burger R., Darcy K.M., Sill M., Greer B.E., Sorosky J..I., and Fruehauf J.P. Relationship between angiogenic markers and clinicopathologic factors/outcome in GOG-170D, a phase II trial of bevacizumab (Bev) in recurrent or persistent epithelial ovarian cancer (EOC) and primary peritoneal cancer (PPC). J Clin Oncol 26 15S (2008)
    • (2008) J Clin Oncol , vol.26 , Issue.15 S
    • Han, E.S.1    Burger, R.2    Darcy, K.M.3    Sill, M.4    Greer, B.E.5    Sorosky, J..I.6    Fruehauf, J.P.7
  • 41
    • 49149108140 scopus 로고    scopus 로고
    • Phase II evaluation of imatinib methylate in the treatment of recurrent or persistent epithelial ovarian or primary peritoneal carcinoma: a Gynecologic Oncology Group study
    • Schilder R.J., Sill M.W., Lee R.B., Shaw T.J., Senterman M.K., Klein-Szanto A.J.P., et al. Phase II evaluation of imatinib methylate in the treatment of recurrent or persistent epithelial ovarian or primary peritoneal carcinoma: a Gynecologic Oncology Group study. J Clin Oncol 26 20 (2008) 3418-3425
    • (2008) J Clin Oncol , vol.26 , Issue.20 , pp. 3418-3425
    • Schilder, R.J.1    Sill, M.W.2    Lee, R.B.3    Shaw, T.J.4    Senterman, M.K.5    Klein-Szanto, A.J.P.6
  • 42
    • 0142188162 scopus 로고    scopus 로고
    • Choice of normal ovarian control influences determination of differentially expressed genes in ovarian cancer expression profiling studies
    • Zorn K.K., Jazaeri A.A., Awtrey C.S., Gardner G.J., Mok S.C., Goyd J., et al. Choice of normal ovarian control influences determination of differentially expressed genes in ovarian cancer expression profiling studies. Clin Cancer Res. 9 13 (2003) 4811-4818
    • (2003) Clin Cancer Res. , vol.9 , Issue.13 , pp. 4811-4818
    • Zorn, K.K.1    Jazaeri, A.A.2    Awtrey, C.S.3    Gardner, G.J.4    Mok, S.C.5    Goyd, J.6
  • 43
    • 25144523393 scopus 로고    scopus 로고
    • Gene expression of serous, endometrioid, and clear cell types of ovarian and endometrial cancer
    • Zorn K.K., Bonome T., Gangi L., Chandramouli G.V., Awtrey C.S., Gardner G.J., et al. Gene expression of serous, endometrioid, and clear cell types of ovarian and endometrial cancer. Clin Cancer Res 11 18 (2005) 6422-6430
    • (2005) Clin Cancer Res , vol.11 , Issue.18 , pp. 6422-6430
    • Zorn, K.K.1    Bonome, T.2    Gangi, L.3    Chandramouli, G.V.4    Awtrey, C.S.5    Gardner, G.J.6
  • 45
    • 3242659798 scopus 로고    scopus 로고
    • Alternative splicing of the multidrug resistance protein 1/ATP binding cassette transporter subfamily gene in ovarian cancer creates functional splice variants and is associated with increased expression of the splicing factors PTB and SRp20
    • He X., Ee P.L., Coon J., and Beck W.T. Alternative splicing of the multidrug resistance protein 1/ATP binding cassette transporter subfamily gene in ovarian cancer creates functional splice variants and is associated with increased expression of the splicing factors PTB and SRp20. Clin Cancer Res 10 4 (2004) 4652-4660
    • (2004) Clin Cancer Res , vol.10 , Issue.4 , pp. 4652-4660
    • He, X.1    Ee, P.L.2    Coon, J.3    Beck, W.T.4
  • 46
    • 34547489950 scopus 로고    scopus 로고
    • Knockdown of polypyrimidine tract-binding protein suppresses ovarian tumor cell growth and invasiveness in vitro
    • He X., Pool M., Darcy K.M., Lim S.B., Auersperg N., Coon J.S., et al. Knockdown of polypyrimidine tract-binding protein suppresses ovarian tumor cell growth and invasiveness in vitro. Oncogene 26 34 (2007) 4961-4968
    • (2007) Oncogene , vol.26 , Issue.34 , pp. 4961-4968
    • He, X.1    Pool, M.2    Darcy, K.M.3    Lim, S.B.4    Auersperg, N.5    Coon, J.S.6
  • 47
    • 0035206038 scopus 로고    scopus 로고
    • BRCA1 germline mutations and polymorphisms in a clinic-based series of ovarian cancer cases: a Gynecologic Oncology Group study
    • Smith S.A., Richards W.E., Caito K., Hanjani P., Markman M., Degeest K., et al. BRCA1 germline mutations and polymorphisms in a clinic-based series of ovarian cancer cases: a Gynecologic Oncology Group study. Gynecol Oncol 83 3 (2001) 586-592
    • (2001) Gynecol Oncol , vol.83 , Issue.3 , pp. 586-592
    • Smith, S.A.1    Richards, W.E.2    Caito, K.3    Hanjani, P.4    Markman, M.5    Degeest, K.6
  • 48
    • 0036095495 scopus 로고    scopus 로고
    • Contribution of BRCA1 and BRCA2 to familial ovarian cancer: a Gynecologic Oncology Group study
    • Reedy M., Gallion H., Fowler J., Kryscio R., and Smith S. Contribution of BRCA1 and BRCA2 to familial ovarian cancer: a Gynecologic Oncology Group study. Gynecol Oncol 85 2 (2002) 255-259
    • (2002) Gynecol Oncol , vol.85 , Issue.2 , pp. 255-259
    • Reedy, M.1    Gallion, H.2    Fowler, J.3    Kryscio, R.4    Smith, S.5
  • 49
    • 41549118839 scopus 로고    scopus 로고
    • A prospective study of risk-reducing salpingo-oophorectomy and longitudinal CA-125 screening among women at increased genetic risk of ovarian cancer: design and baseline characteristics: a Gynecologic Oncology Group study
    • Greene M.H., Piedmonte M., Alberts D., Gail M., Hensley M., Miner Z., et al. A prospective study of risk-reducing salpingo-oophorectomy and longitudinal CA-125 screening among women at increased genetic risk of ovarian cancer: design and baseline characteristics: a Gynecologic Oncology Group study. Cancer Epidemiol Biomarkers Prev 17 3 (2008) 594.604
    • (2008) Cancer Epidemiol Biomarkers Prev , vol.17 , Issue.3
    • Greene, M.H.1    Piedmonte, M.2    Alberts, D.3    Gail, M.4    Hensley, M.5    Miner, Z.6
  • 50
    • 71049194443 scopus 로고    scopus 로고
    • Common variants in 8q24, LSP1 and 2q35 and breast cancer risk for BRCA1 and BRCA2 mutation carriers
    • Antoniou A.C., Sinilnikova O., McGuffog L., Healey S., Nevanlinna H., Simard J., et al. Common variants in 8q24, LSP1 and 2q35 and breast cancer risk for BRCA1 and BRCA2 mutation carriers. Hum Mol Genet 18 22 (2009) 4442-4456
    • (2009) Hum Mol Genet , vol.18 , Issue.22 , pp. 4442-4456
    • Antoniou, A.C.1    Sinilnikova, O.2    McGuffog, L.3    Healey, S.4    Nevanlinna, H.5    Simard, J.6
  • 51
    • 0032866504 scopus 로고    scopus 로고
    • Selective changes in EGF receptor expression and function during the proliferation, functional differentiation and apoptosis of mammary epithelial cells
    • Darcy K.M., Wohlhueter A.L., Zangani D., Vaughan M.M., Russell J.A., Masso-Welch P.A., et al. Selective changes in EGF receptor expression and function during the proliferation, functional differentiation and apoptosis of mammary epithelial cells. Euro J Cell Biol 78 (1999) 511-523
    • (1999) Euro J Cell Biol , vol.78 , pp. 511-523
    • Darcy, K.M.1    Wohlhueter, A.L.2    Zangani, D.3    Vaughan, M.M.4    Russell, J.A.5    Masso-Welch, P.A.6
  • 52
    • 0033977969 scopus 로고    scopus 로고
    • Changes in ErbB2 (HER-2/neu), ErbB3 and ErbB4 during the growth, differentiation and apoptosis of normal rat mammary epithelial cells
    • Darcy K.M., Zangani D., Wohlhueter A.L., Huang R.-Y., Vaughan M.M., Russell J.A., et al. Changes in ErbB2 (HER-2/neu), ErbB3 and ErbB4 during the growth, differentiation and apoptosis of normal rat mammary epithelial cells. J Histochem Cytochem 48 1 (2000) 63-80
    • (2000) J Histochem Cytochem , vol.48 , Issue.1 , pp. 63-80
    • Darcy, K.M.1    Zangani, D.2    Wohlhueter, A.L.3    Huang, R.-Y.4    Vaughan, M.M.5    Russell, J.A.6
  • 53
    • 77951939494 scopus 로고    scopus 로고
    • http://www.sigmaaldrich.com/life-science/cell-biology/learning-center/pathway-slides-and/signaling-pathways.html.
  • 54
    • 77951938474 scopus 로고    scopus 로고
    • http://www.sigmaaldrich.com/life-science/cell-biology/learning-center/pathway-slides-and/regulatory-cascade-of-cyclin-gene-expression.html.
  • 55
    • 77951937445 scopus 로고    scopus 로고
    • http://www.sigmaaldrich.com/life-science/cell-biology/learning-center/pathway-slides-and/g1-and-s-phases-of-the-cell-cycle.html.
  • 56
    • 63049110664 scopus 로고    scopus 로고
    • Excision repair cross-complementation group 1 (ERCC1) in platinum-based treatment of non-small cell lung cancer with special emphasis on carboplatin: a review of current literature
    • Vilmar A., and Sørensen J.B. Excision repair cross-complementation group 1 (ERCC1) in platinum-based treatment of non-small cell lung cancer with special emphasis on carboplatin: a review of current literature. Lung Cancer 64 2 (2009) 131-139
    • (2009) Lung Cancer , vol.64 , Issue.2 , pp. 131-139
    • Vilmar, A.1    Sørensen, J.B.2
  • 57
    • 25444517122 scopus 로고    scopus 로고
    • Good timing in the cell cycle for precise DNA repair by BRCA1
    • Durant S.T., and Nickoloff J.A. Good timing in the cell cycle for precise DNA repair by BRCA1. Cell Cycle 4 9 (2005) 1216-1222
    • (2005) Cell Cycle , vol.4 , Issue.9 , pp. 1216-1222
    • Durant, S.T.1    Nickoloff, J.A.2
  • 58
    • 49249138928 scopus 로고    scopus 로고
    • Sporadic epithelial ovarian cancer: clinical relevance of BRCA1 inhibition in the DNA damage and repair pathway
    • Weberpals J.I., Clark-Knowles K.V., and Vanderhyden B.C. Sporadic epithelial ovarian cancer: clinical relevance of BRCA1 inhibition in the DNA damage and repair pathway. J Clin Oncol 26 19 (2008) 3259-3267
    • (2008) J Clin Oncol , vol.26 , Issue.19 , pp. 3259-3267
    • Weberpals, J.I.1    Clark-Knowles, K.V.2    Vanderhyden, B.C.3
  • 59
    • 70350222210 scopus 로고    scopus 로고
    • Recent advances in cancer therapy targeting proteins involved in DNA double-strand repair
    • Bolderson E., Richard D.J., Zhou B.-B.S., and Khanna K.K. Recent advances in cancer therapy targeting proteins involved in DNA double-strand repair. Clin Cancer Res 15 20 (2009) 6314-6320
    • (2009) Clin Cancer Res , vol.15 , Issue.20 , pp. 6314-6320
    • Bolderson, E.1    Richard, D.J.2    Zhou, B.-B.S.3    Khanna, K.K.4


* 이 정보는 Elsevier사의 SCOPUS DB에서 KISTI가 분석하여 추출한 것입니다.