The structures of the C185S and C185A mutants of sulfite oxidase reveal rearrangement of the active site

Biochemistry

Volumn 49, Issue 18, 2010, Pages 3989-4000

  Qiu, James A ^a   Wilson, Heather L ^a   Pushie, M Jake ^b   Kisker, Caroline ^c   George, Graham N ^b   Rajagopalan, K V ^a  

^a DUKE UNIVERSITY MEDICAL CENTER   (United States)

^b UNIVERSITY OF SASKATCHEWAN   (Canada)

^c UNIVERSITY OF WÜRZBURG   (Germany)

Author keywords

[No Author keywords available]

Indexed keywords

AMINO ACIDS; ANIMALS; ATOMS; BOND LENGTH; CATALYSIS; CATALYST ACTIVITY; DENSITY FUNCTIONAL THEORY; EXTENDED X RAY ABSORPTION FINE STRUCTURE SPECTROSCOPY; LIGANDS; MOLYBDENUM COMPOUNDS; OXIDATION; SULFUR COMPOUNDS; X RAY ABSORPTION;

ACTIVE SITE RESIDUES; AMINO ACID SEQUENCE; CATALYTIC MECHANISMS; CONFORMATIONAL CHANGE; COORDINATION ENVIRONMENT; ENZYMATIC ACTIVITIES; EXTENDED XRAY ABSORPTION FINE STRUCTURE (EXAFS) SPECTROSCOPIES; REACTION MECHANISM;

CRYSTAL ATOMIC STRUCTURE;

ALANINE; CYSTEINE; RECOMBINANT ENZYME; SERINE; SULFITE; SULFITE OXIDASE; SULFUR; TYROSINE;

ARTICLE; CATALYSIS; CONTROLLED STUDY; CRYSTAL STRUCTURE; CRYSTALLIZATION; CRYSTALLOGRAPHY; DENSITY FUNCTIONAL THEORY; ENZYME ACTIVE SITE; ENZYME ACTIVITY; ENZYME CONFORMATION; ENZYME STRUCTURE; GENETIC VARIABILITY; MOLECULAR INTERACTION; OXIDATION; PRIORITY JOURNAL; SPECTROSCOPY; X RAY;

EID: 77951917143     PISSN: 00062960     EISSN: 15204995     Source Type: Journal    
DOI: 10.1021/bi1001954     Document Type: Article

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