Determinants of Tc-99m sestamibi SPECT scan sensitivity in primary hyperparathyroidism

American Journal of Surgery

Volumn 199, Issue 5, 2010, Pages 614-620

  Swanson, Todd W ^a   Chan, Simon K ^a   Jones, Steven J ^a   Bugis, Samuel ^a   Irvine, Robert ^a   Belzberg, Allan ^a   Levine, Daniel ^a   Wiseman, Sam M ^a  

^a UNIVERSITY OF BRITISH COLUMBIA   (Canada)

Author keywords

Parathyroid surgery; Primary hyperparathyroidism; Sestamibi scan

Indexed keywords

ACETYLSALICYLIC ACID; ALPHA ADRENERGIC RECEPTOR BLOCKING AGENT; ANTIBIOTIC AGENT; ANTIHYPERTENSIVE AGENT; ANTILIPEMIC AGENT; ATYPICAL ANTIPSYCHOTIC AGENT; BETA ADRENERGIC RECEPTOR BLOCKING AGENT; BISPHOSPHONIC ACID DERIVATIVE; CALCIUM CHANNEL BLOCKING AGENT; CALCIUM ION; COLCHICINE; CORTICOSTEROID; DIPEPTIDYL CARBOXYPEPTIDASE INHIBITOR; HISTAMINE H2 RECEPTOR ANTAGONIST; HYDROXYMETHYLGLUTARYL COENZYME A REDUCTASE INHIBITOR; INSULIN; LOOP DIURETIC AGENT; METHOXY ISOBUTYL ISONITRILE TECHNETIUM TC 99M; MUSCLE RELAXANT AGENT; NONSTEROID ANTIINFLAMMATORY AGENT; OPIATE; PROKINETIC AGENT; PROTON PUMP INHIBITOR; SEROTONIN NORADRENALIN REUPTAKE INHIBITOR; SEROTONIN UPTAKE INHIBITOR; SULFONYLUREA; THIAZIDE DIURETIC AGENT; THYROXINE; UNINDEXED DRUG; URSODEOXYCHOLIC ACID;

ADULT; ARTICLE; CONTROLLED STUDY; DIAGNOSTIC ACCURACY; FALSE NEGATIVE RESULT; FALSE POSITIVE RESULT; FEMALE; HUMAN; HYPOTHYROIDISM; MAJOR CLINICAL STUDY; MALE; MEDICAL RECORD REVIEW; PARATHYROID ADENOMA; PARATHYROIDECTOMY; PREOPERATIVE EVALUATION; PRIMARY HYPERPARATHYROIDISM; PRIORITY JOURNAL; SENSITIVITY AND SPECIFICITY; SINGLE PHOTON EMISSION COMPUTER TOMOGRAPHY; TUMOR VOLUME;

ADENOMA; AGED; COHORT STUDIES; FALSE POSITIVE REACTIONS; FEMALE; HUMANS; HYPERPARATHYROIDISM, PRIMARY; MALE; MIDDLE AGED; PARATHYROID NEOPLASMS; PARATHYROIDECTOMY; PREOPERATIVE CARE; PROBABILITY; RETROSPECTIVE STUDIES; RISK ASSESSMENT; SENSITIVITY AND SPECIFICITY; TECHNETIUM TC 99M SESTAMIBI; TOMOGRAPHY, EMISSION-COMPUTED, SINGLE-PHOTON; TREATMENT OUTCOME;

EID: 77951907955     PISSN: 00029610     EISSN: None     Source Type: Journal    
DOI: 10.1016/j.amjsurg.2010.02.001     Document Type: Article

References (27)

1. Consensus Development Conference Panel. Diagnosis and management of asymptomatic primary hyperparathyroidism: consensus development conference statement. Ann Intern Med 114 (1991) 593-597
2. Coakley A.J., Kettle A.G., Wells C.P., O'Doharty M.J., and Collins R.E.C. 99m Tc-sestamibi-a new agent for parathyroid imaging 1989. Nucl Med Commun 10 (1989) 791-794
3. Casas A.T., Burke G.J., Arlie R., Mansberger J., and Wei J.P. Impact of technetium-99m-sestamibi localization on operative time and success of operations for primary hyperparathyroidism. Am Surg 60 (1994) 12-16
4. Sebag F., Hubbard J.G., Maweja S., Misso C., Tardivet L., and Henry J.F. Negative preoperative localization studies are highly predictive of multiglandular disease in sporadic primary hyperparathyroidism. Surgery 134 (2003) 1038-1041
5. Chiu B., Sturgeon C., and Angelos P. What is the link between nonlocalizing sestamibi scans, multigland disease, and persistent hypercalcemia?. A study of 401 consecutive patients undergoing parathyroidectomy. Surgery 140 (2006) 418-422
6. O'Doherty M.J., Kettle A.G., Wells P., Collins R.E.C., and Coakley A.J. Parathyroid imaging with technetitum-99m-sestamibi: preoperative localization and tissue uptake studies. J Nucl Med 33 (1992) 313-318
7. Erbil Y., Kapran Y., Issever H., et al. The positive effect of adenoma weight and oxyphil cell content on preoperative localization with 99mTc-sestamibi scanning for primary hyperparathyroidism. Am J Surg 195 (2008) 34-39
8. Pons F., Torregrosa I.V., and Fuster D. Biologic factors influencing parathyroid localization. Nucl Med Commun 24 (2003) 121-124
9. Fuster D., Ybarra J., Torregrosa J.V., et al. Double-phase parathyroid 99m Tc-sestamibi scintigraphy in chronic hemodialysis patients: correlation with biochemical markers of parathyroid function. Nucl Med Commun 24 (2003) 85-90
10. Royal R.E., Delpassand E.S., Shapiro S.E., et al. Improving the yield of preoperative parathyroid localization: technetium 99m-sestamibi imaging after thyroid suppression. Surgery 132 (2002) 968-974
11. Gotthardt M., Lohmann B., Behr T.M., et al. Clinical value of parathyroid scintigraphy with technetium-99m methoxyisobutylisonitrile: discrepancies in clinical data and a systematic metaanalysis of the literature. World J Surg 28 (2004) 100-107
12. Hetrakul N., Civelek C., Stagg C.A., and Udelsman R. In vitro accumulation of technetium-99m-sestamibi in human parathyroid mitochondria. Surgery 130 (2001) 1011-1018
13. Mitchell B.K., Cornelius E.Q., Zoghbi S., and Kinder B.K. Mechanism of technetium 99m sestamibi parathyroid imaging and the possible role of p-glycoprotein. Surgery 120 (1996) 1039-1046
14. Yamaguchi S., Yachiku S., and Hashimoto H.W. Relationship between technetium 99m-methoxyisobutylisonitrile and the multidrug resistant protein in parathyroid glands. J Surg 26 (2002) 29-34
15. Shiau Y.C., Tsai S.C., Wang J.J., Ho S.T., and Kao A. Detecting parathyroid adenoma using technetium-99m tetrofosmin: comparison with P-glycoprotein and multidrug resistance related protein expression-a preliminary report. Nucl Med Biol 29 (2002) 339-344
16. Huang W.E. Size and p-glycoprotein expression limit 99mTc-tetrofosmin uptake in parathyroid adenoma. Nucl Med Commun 23 (2002) 1001-1004
17. Ballinger J.R., Hua H.A., Berry B.W., Birby P., and Boxen I. 99Tcm-sestamibi as an agent for the imaging P-glycoprotein-mediated multi-drug resistance: in vitro and in vivo studies in a rat breast tumour cell line and its doxorubicin-resistant variant. Nucl Med Commun 16 (1995) 253-257
18. Pariante C.M. The role of multi-drug resistance p-glycoprotein in glucocorticoid function: studies in animals and relevance in humans. Eur J Pharmacol 583 (2008) 263-271
19. Patrignani P., Tacconelli S., Sciulli M.G., and Capone M.L. New insights into COX-2 biology and inhibition. Brain Res Rev 48 (2005) 352-359
20. Arbab A.S., Koizumi K., Toyama K., Arai T., and Araki T. Effects of ion channel modulators in the infux and efflux of Tc-99m-MI. Ann Nucl Med 13 (1999) 27-32
21. Arbab A.S., Ueki J., Koisumi K., and Araki T. Effects of extracellular Na+ and Ca2+ ions and Ca2+ channel modulators on the cell-associated activity of 99mTc-MIBI and 99mTc-tetrofosmin in tumour cells. Nucl Med Commun 24 (2003) 155-166
22. Friedman K., Somervell H., Patel P., et al. Effect of calcium channel blockers on the sensitivity of preoperative 99m Tc-MIBI SPECT for hyperparathyoidims. Surgery 136 (2004) 1199-1204
23. MacQueen J.B. Some methods for classification and analysis of multivariate observations. Proc 5th Berkeley Symp Math Statist Prob 1 (1967) 281-297
24. Han J., and Kamber M. Data Mining: Concepts and Techniques (2001), Morgan Kaufmann, New York
25. Pavlidis P., and Noble W.S. Matrix2png: a utility for visualizing matrix data. Bioinformatics 19 (2003) 295-296
26. Bandeira F.A., Oliveira R.I., Griz L.H., Caldas G., and Bandeira C. Differences in accuracy of 99mTc-sestamibi scanning between severe and mild forms of primary hyperparathyroidism. J Nucl Med Technol 36 (2008) 30-35
27. Sywak M.S., Knowlton S.T., Pasieka J.L., Parsons L.L., and Jones J. Do the National Institutes of Health consensus guidelines for parathyroidectomy predict symptom severity and surgical outcome in patients with primary hyperparathyroidism?. Surgery 132 (2002) 1013-1019