Potential role of everolimus in inducing cholestasis

Annals of Oncology

Volumn 21, Issue 2, 2010, Pages 433-433

  Pantano, F ^a   Santini, D ^a   Guida, F ^a   Vincenzi, B ^a   Tonini, G ^a  

^a UNIVERSITY CAMPUS BIO MEDICO   (Italy)

Author keywords

[No Author keywords available]

Indexed keywords

ALKALINE PHOSPHATASE; EVEROLIMUS; GAMMA GLUTAMYLTRANSFERASE; PROTEIN TYROSINE KINASE INHIBITOR; ANTINEOPLASTIC AGENT; DRUG DERIVATIVE; PROTEIN KINASE INHIBITOR; RAPAMYCIN;

ALKALINE PHOSPHATASE BLOOD LEVEL; BLOOD ANALYSIS; CASE REPORT; CHOLANGIOGRAPHY; CLINICAL FEATURE; COMPUTER ASSISTED TOMOGRAPHY; DIFFERENTIAL DIAGNOSIS; DRUG TREATMENT FAILURE; GAMMA GLUTAMYL TRANSFERASE BLOOD LEVEL; HUMAN; HYPERCHOLESTEROLEMIA; HYPERTRIGLYCERIDEMIA; INTRAHEPATIC CHOLESTASIS; KIDNEY METASTASIS; LETTER; NUCLEAR MAGNETIC RESONANCE IMAGING; PRIORITY JOURNAL; SIDE EFFECT; CHEMICALLY INDUCED DISORDER; CHOLESTASIS; DRUG EFFECT; DRUG RESISTANCE; KIDNEY CARCINOMA; KIDNEY TUMOR; METASTASIS; PATHOLOGY; SALVAGE THERAPY;

ANTINEOPLASTIC AGENTS; CARCINOMA, RENAL CELL; CHOLESTASIS; DRUG RESISTANCE, NEOPLASM; HUMANS; KIDNEY NEOPLASMS; NEOPLASM METASTASIS; PROTEIN KINASE INHIBITORS; SALVAGE THERAPY; SIROLIMUS;

EID: 77951907726     PISSN: 09237534     EISSN: 15698041     Source Type: Journal    
DOI: 10.1093/annonc/mdp558     Document Type: Letter

References (5)

1. Motzer RJ, Escudier B, Oudard S et al. on behalf of the RECORD-1 Study Group. Efficacy of everolimus in advanced renal cell carcinoma: a double-blind, randomised, placebo-controlled phase III trial. Lancet 2008; 372: 449-456.
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4. Bhojani N, Jeldres C, Patard JJ et al. Toxicities associated with the administration of sorafenib, sunitinib, and temsirolimus and their management in patients with metastatic renal cell carcinoma. Eur Urol 2008; 53(5): 917-930.
5. Bramow S, Ott P, Thomsen Nielsen F et al. Cholestasis and regulation of genes related to drug metabolism and biliary transport in rat liver following treatment with cyclosporine A and sirolimus (Rapamycin). Pharmacol Toxicol 2001; 89: 133-139.