RA induces the neural-like cells generated from epigenetic modified NIH/3T3 cells

Molecular Biology Reports

Volumn 37, Issue 3, 2010, Pages 1197-1202

  Zhang, Xi Mei ^a   Li, Qiu Ming ^a   Su, Dong Ju ^a   Wang, Ning ^a   Shan, Zhi Yan ^a   Jin, Lian Hong ^a   Lei, Lei ^a  

^a HARBIN MEDICAL UNIVERSITY   (China)

Author keywords

Epigenesis; Fibroblasts; Neuron

Indexed keywords

BETA3 TUBULIN; DNA; KRUPPEL LIKE FACTOR 4; MEMBRANE PROTEIN; MYC PROTEIN; NESTIN; NEUROFILAMENT PROTEIN; NEURON SPECIFIC ENOLASE; OCTAMER TRANSCRIPTION FACTOR 4; RETINOIC ACID; TRANSCRIPTION FACTOR SOX2; UNCLASSIFIED DRUG; 5 AZA 2' DEOXYCYTIDINE; AZACITIDINE; DRUG DERIVATIVE; ENOLASE; INTERMEDIATE FILAMENT PROTEIN; KRUPPEL LIKE FACTOR; MYC PROTEIN, MOUSE; NERVE PROTEIN; POU5F1 PROTEIN, MOUSE; SOX2 PROTEIN, MOUSE; TRANSCRIPTION FACTOR SOX;

ARTICLE; CELL DEDIFFERENTIATION; CELL DIFFERENTIATION; CELL STRAIN 3T3; CONTROLLED STUDY; DNA METHYLATION; EPIGENETICS; FIBROBLAST; FIBROBLAST CULTURE; GENE EXPRESSION; NERVE CELL; ANIMAL; CYTOLOGY; DRUG EFFECT; FLOW CYTOMETRY; GENE EXPRESSION PROFILING; GENE EXPRESSION REGULATION; GENETIC EPIGENESIS; IMMUNOHISTOCHEMISTRY; METABOLISM; MOUSE; PHYSIOLOGY; REVERSE TRANSCRIPTION POLYMERASE CHAIN REACTION;

ANIMALS; AZACITIDINE; CELL DIFFERENTIATION; DNA METHYLATION; EPIGENESIS, GENETIC; FLOW CYTOMETRY; GENE EXPRESSION PROFILING; GENE EXPRESSION REGULATION; IMMUNOHISTOCHEMISTRY; INTERMEDIATE FILAMENT PROTEINS; KRUPPEL-LIKE TRANSCRIPTION FACTORS; MICE; NERVE TISSUE PROTEINS; NEURONS; NIH 3T3 CELLS; OCTAMER TRANSCRIPTION FACTOR-3; PHOSPHOPYRUVATE HYDRATASE; PROTO-ONCOGENE PROTEINS C-MYC; REVERSE TRANSCRIPTASE POLYMERASE CHAIN REACTION; SOXB1 TRANSCRIPTION FACTORS; TRETINOIN;

EID: 77951894073     PISSN: 03014851     EISSN: 15734978     Source Type: Journal    
DOI: 10.1007/s11033-009-9489-3     Document Type: Article

References (25)

1. Reubinoff BE, Pera MF, Fong CY, Trounson A, Bongso A (2000) Embryonic stem cell lines from human blastocysts: Somatic differentiation in vitro. Nat Biotechnol 18:399-404. doi:10.1038/ 74447
2. Thomson JA, Itskovitz-Eldor J, Shapiro SS, Waknitz MA, Swiergiel JJ, Marshall VS et al (1998) Embryonic stem cell lines derived from human blastocysts. Science 282:1145-1147. doi: 10.1126/science.282.5391.1145
3. Hochedlinger K, Jaenisch R (2006) Nuclear reprogramming and pluripotency. Nature 441:1061-1067. doi:10.1038/nature04955
4. Collas P, Taranger CK (2006) Epigenetic reprogramming of nuclei using cell extracts. Stem Cell Rev 2:309-317. doi:10.1007/ BF02698058
5. Alberio R, Campbell KH, Johnson AD (2006) Reprogramming somatic cells into stem cells. Reproduction 132:709-720. doi: 10.1530/rep.1.01077
6. Takahashi K, Tanabe K, Ohnuki M, Narita M, Ichisaka T, Tomoda K et al (2007) Induction of pluripotent stem cells from adult human fibroblasts by defined factors. Cell 131:861-872. doi:10.1016/j.cell.2007.11.019
7. Wernig M, Meissner A, Foreman R, Brambrink T, Ku M, Hochedlinger K et al (2007) In vitro reprogramming of fibroblasts into a pluripotent ES-cell-like state. Nature 448:318-324. doi: 10.1038/nature05944
8. Takahashi K, Yamanaka S (2006) Induction of pluripotent stem cells from mouse embryonic and adult fibroblast cultures by defined factors. Cell 126:663-676. doi:10.1016/j.cell.2006. 07.024
9. Hanna J, Wernig M, Markoulaki S, Sun CW, Meissner A, Cassady JP, Beard C, Brambrink T, Wu LC, Townes TM, Jaenisch R (2007) Treatment of sickle cell anemia mouse model with iPS cells generated from autologous skin. Science 318:1920-1923. doi:10.1126/science.1152092
10. Li E (2002) Chromatin modification and epigenetic reprogramming in mammalian development. Nat Rev Genet 3:662-673. doi:10.1038/nrg887
11. Jaenisch R, Bird A (2003) Epigenetic regulation of gene expression: How the genome integrates intrinsic and environmental signals. Nat Genet 33:245-254. doi:10.1038/ng1089
12. Alexanian AR (2007) Epigenetic modifiers promote efficient generation of neural-like cells from bone marrow-derived mesenchymal cells grown in neural environment. J Cell Biochem 100:362-371. doi:10.1002/jcb.21029
13. Kass SU, Pruss D, Wolffe AP (1997) How does DNA methylation repress transcription? Trends Genet 13:444-449. doi: 10.1016/S0168-9525(97)01268-7
14. Benjamin D, Jost JP (2001) Reversal of methylationmediated repression with short-chain fatty acids: Evidence for an additional mechanism to histone deacetylation. Nucleic Acids Res 29:3603-3610. doi:10.1093/nar/29.17.3603
15. Kohyama J, Abe H, Shimazaki T, Koizumi A, Nakashima K, Gojo S et al (2001) Brain from bone: Efficient "meta-differentiation" of marrow stroma-derived mature osteoblasts to neurons with Noggin or a demethylating agent. Differentiation 68:235-244. doi:10.1046/j.1432-0436.2001.680411.x
16. Reik W, Dean W, Walter J (2001) Epigenetic reprogramming in mammalian development. Science 293:1089-1093. doi:10.1126/ science.1063443
17. Milhem M, Mahmud N, Lavelle D, Araki H, DeSimone J, Saunthararajah Y et al (2004) Modification of hematopoietic stem cell fate by 5-aza-20-deoxycytidine and trichostatin A. Blood 103:4102-4110. doi:10.1182/blood-2003-07-2431
18. Enright BP, Kubota C, Yang X, Tian XC (2003) Epigenetic characteristics and development of embryos cloned from donor cells treated by trichostatin A or 5-aza-20-deoxycytidine. Biol Reprod 69:896-901. doi:10.1095/biolreprod.103. 017954
19. Habib M, Fares F, Bourgeois CA, Bella C, Bernardino J et al (1999) DNA global hypomethylation in EBV-transformed interphase nuclei. Exp Cell Res 249:46-53. doi:10.1006/excr. 1999.4434
20. Imamura T, Ohgane J, Ito S, Ogawa T, Hattori N, Tanaka S et al (2004) CpG island of rat sphingosine kinase-1 gene: Tissuedependent DNA methylation status and multiple alternative first exons. J Biol Chem 279:17063-17069. doi:10.1074/jbc. M309002200
21. Ohgane J, Aikawa J, Ogura A, Hattori N, Ogawa T, ShiotaK(1998) Analysis of CpG islands of trophoblast giant cells by restriction landmark genomic scanning. Dev Genet 22:132-140. doi:10.1002/ (SICI)1520-6408(1998)22:2\132::AID- DVG3[3.0.CO;2-7
22. Hattori N, Nishino K, Ko YG, Hattori N, Ohgane J, Tanaka S et al (2004) Epigenetic control of mouse Oct-4 gene expression in embryonic stem cells and trophoblast stem cells. J Biol Chem 279:17063-17069. doi:10.1074/jbc.M309002200
23. Lendahl U, Zimmerman LB, McKay RD (1999) CNS stem cells express a new class of intermediate filament protein. Cell 60:585-595. doi:10.1016/0092- 8674(90)90662-X
24. Cattaneo E, McKay R (1990) Proliferation and differentiation of neuronal stem cells regulated by nerve growth factor. Nature 347:762-765. doi:10.1038/347762a0
25. Li M, Pevny L, Lovell-Badge R, Smith A (1998) Generation of purified neural precursors from embryonic stem cells by lineage selection. Curr Biol 8:971-974. doi:10.1016/S0960-9822(98) 70399-9