Recombinant adenovirus vector Ad-hIL-10 protects grafts from cold ischemia-reperfusion injury following orthotopic liver transplantation in rats

Hepatobiliary and Pancreatic Diseases International

Volumn 9, Issue 2, 2010, Pages 144-148

  Si, Zhong Zhou ^a   Li, Jie Qun ^a   Qi, Hai Zhi ^a   He, Zhi Jun ^a   Hu, Wei ^a   Li, Yi Ning ^a  

^a CENTRAL SOUTH UNIVERSITY   (China)

Author keywords

Adenovirus vector; interleukin 10; Gene transfer; Ischemia reperfusion injury

Indexed keywords

ADENOVIRUS VECTOR; BETA GALACTOSIDASE; IMMUNOGLOBULIN ENHANCER BINDING PROTEIN; INTERCELLULAR ADHESION MOLECULE 1; INTERLEUKIN 10; MACROPHAGE INFLAMMATORY PROTEIN 2; MESSENGER RNA; RINGER LACTATE SOLUTION; TUMOR NECROSIS FACTOR ALPHA;

ANIMAL EXPERIMENT; ANIMAL TISSUE; ARTICLE; COLD ISCHEMIA; CONTROLLED STUDY; CYTOKINE PRODUCTION; HISTOPATHOLOGY; LIVER FUNCTION TEST; LIVER INJURY; LIVER ISCHEMIA; LIVER TRANSPLANTATION; NONHUMAN; PROTEIN EXPRESSION; RAT; REPERFUSION INJURY; REVERSE TRANSCRIPTION POLYMERASE CHAIN REACTION; TISSUE PRESERVATION; VIRUS RECOMBINANT; WESTERN BLOTTING;

ADENOVIRIDAE; ANIMALS; GENE THERAPY; GENETIC VECTORS; HUMANS; INTERLEUKIN-10; ISCHEMIA; LIVER TRANSPLANTATION; NF-KAPPA B; RATS; RATS, SPRAGUE-DAWLEY; REPERFUSION INJURY; TRANSPLANTATION, HOMOLOGOUS;

EID: 77951875196     PISSN: 14993872     EISSN: None     Source Type: Journal    
DOI: None     Document Type: Article

References (30)

1. Sun HW, Shen F, Zhou YM. Influence of perfusion by gaseous oxygen persufflation on rat donor liver. Hepatobiliary Pancreat Dis Int 2006;5:195-198. (Pubitemid 43826906)
2. Howard TK, Klintmalm GB, Cofer JB, Husberg BS, Goldstein RM, Gonwa TA. The influence of preservation injury on rejection in the hepatic transplant recipient. Transplantation 1990;49:103-107.
3. de Waal Malefyt R, Abrams J, Bennett B, Figdor CG, de Vries JE. Interleukin 10(IL-10) inhibits cytokine synthesis by human monocytes: an autoregulatory role of IL-10 produced by monocytes. J Exp Med 1991;174:1209-1220.
4. Dagvadorj J, Naiki Y, Tumurkhuu G, Hassan F, Islam S, Koide N, et al. Interleukin-10 inhibits tumor necrosis factor-alpha production in lipopolysaccharide-stimulated RAW 264.7 cells through reduced MyD88 expression. Innate Immun 2008;14:109-115.
5. Tudor C, Marchese FP, Hitti E, Aubareda A, Rawlinson L, Gaestel M, et al. The p38 MAPK pathway inhibits tristetraprolin-directed decay of interleukin-10 and proinflammatory mediator mRNAs in murine macrophages. FEBS Lett 2009;583:1933-1938.
6. Cassatella MA, Meda L, Bonora S, Ceska M, Constantin G. Interleukin 10 (IL-10) inhibits the release of proinflammatory cytokines from human polymorphonuclear leukocytes. Evidence for an autocrine role of tumor necrosis factor and IL-1 beta in mediating the production of IL-8 triggered by lipopolysaccharide. J Exp Med 1993;178:2207-2211. (Pubitemid 23344879)
7. Yoshidome H, Kato A, Edwards MJ, Lentsch AB. Interleukin-10 suppresses hepatic ischemia/reperfusion injury in mice: implications of a central role for nuclear factor kappaB. Hepatology 1999;30:203-208. (Pubitemid 29300587)
8. Wissing KM, Morelon E, Legendre C, De Pauw L, LeBeaut A, Grint P, et al. A pilot trial of recombinant human interleukin-10 in kidney transplant recipients receiving OKT3 induction therapy. Transplantation 1997;64:999-1006. (Pubitemid 27446766)
9. Donckier V, Loi P, Closset J, Nagy N, Quertinmont E, Le Moine O, et al. Preconditioning of donors with interleukin-10 reduces hepatic ischemia-reperfusion injury after liver transplantation in pigs. Transplantation 2003;75:902-904. (Pubitemid 36373468)
10. Blazar BR, Taylor PA, Smith S, Vallera DA. Interleukin-10 administration decreases survival in murine recipients of major histocompatibility complex disparate donor bone marrow grafts. Blood 1995;85:842-851.
11. Li JQ, Qi HZ, He ZJ, Hu W, Si ZZ, Li YN, et al. Cytoprotective effects of human interleukin-10 gene transfer against necrosis and apoptosis induced by hepatic cold ischemia/reperfusion injury. J Surg Res 2009;157:e71-78.
12. Kamada N, Calne RY. A surgical experience with five hundred thirty liver transplants in the rat. Surgery 1983;93:64-69. (Pubitemid 13093408)
13. Suzuki S, Toledo-Pereyra LH, Rodriguez FJ, Cejalvo D. Neutrophil infiltration as an important factor in liver ischemia and reperfusion injury. Modulating effects of FK506 and cyclosporine. Transplantation 1993;55:1265-1272. (Pubitemid 23183235)
14. Ke B, Ritter T, Kato H, Zhai Y, Li J, Lehmann M, et al. Regulatory cells potentiate the efficacy of IL-4 gene transfer by up-regulating Th2-dependent expression of protective molecules in the infectious tolerance pathway in transplant recipients. J Immunol 2000;164:5739-5745. (Pubitemid 30389816)
15. Matsuno T, Sasaki H, Nakagawa K, Ishido N, Matsuda H, Sadamori H, et al. Fas antigen expression and apoptosis in kidney allografts. Transplant Proc 1997;29:177-178. (Pubitemid 27123365)
16. Jaeschke H, Bautista AP, Spolarics Z, Spitzer JJ. Superoxide generation by Kupffer cells and priming of neutrophils during reperfusion after hepatic ischemia. Free Radic Res Commun 1991;15:277-284.
17. Colletti LM, Cortis A, Lukacs N, Kunkel SL, Green M, Strieter RM. Tumor necrosis factor up-regulates intercellular adhesion molecule 1, which is important in the neutrophildependent lung and liver injury associated with hepatic ischemia and reperfusion in the rat. Shock 1998;10:182-191.
18. Kuboki S, Shin T, Huber N, Eismann T, Galloway E, Schuster R, et al. Hepatocyte signaling through CXC chemokine receptor-2 is detrimental to liver recovery after ischemia/ reperfusion in mice. Hepatology 2008;48:1213-1223.
19. Jaeschke H, Smith CW. Mechanisms of neutrophil-induced parenchymal cell injury. J Leukoc Biol 1997;61:647-653. (Pubitemid 27276056)
20. Llacuna L, MaríM, Lluis JM, García-Ruiz C, Fernádez Checa JC, Morales A. Reactive oxygen species mediate liver injury through parenchymal nuclear factor-kappaB inactivation in prolonged ischemia/ reperfusion. Am J Pathol 2009;174:1776-1785.
21. Collart MA, Baeuerle P, Vassalli P. Regulation of tumor necrosis factor alpha transcription in macrophages: involvement of four kappa B-like motifs and of constitutive and inducible forms of NF-kappa B. Mol Cell Biol 1990;10:1498-1506. (Pubitemid 20105021)
22. Stein B, Baldwin AS Jr. Distinct mechanisms for regulation of the interleukin-8 gene involve synergism and coopera-tivity between C/EBP and NF-kappa B. Mol Cell Biol 1993;13: 7191-7198. (Pubitemid 23321171)
23. Widmer U, Manogue KR, Cerami A, Sherry B. Genomic cloning and promoter analysis of macrophage inflammatory protein (MIP)-2, MIP-1 alpha, and MIP-1 beta, members of the chemokine superfamily of proinflammatory cytokines. J Immunol 1993;150:4996-5012. (Pubitemid 23150367)
24. Collins T, Read MA, Neish AS, Whitley MZ, Thanos D, Maniatis T. Transcriptional regulation of endothelial cell adhesion molecules: NF-kappa B and cytokine-inducible enhancers. FASEB J 1995;9:899-909.
25. Ghosh S, May MJ, Kopp EB. NF-kappa B and Rel proteins: evolutionarily conserved mediators of immune responses. Annu Rev Immunol 1998;16:225-260. (Pubitemid 28183365)
26. Funaki H, Shimizu K, Harada S, Tsuyama H, Fushida S, Tani T, et al. Essential role for nuclear factor kappaB in ischemic preconditioning for ischemia-reperfusion injury of the mouse liver. Transplantation 2002;74:551-556. (Pubitemid 34977688)
27. Ricciardi R, Shah SA, Wheeler SM, Quarfordt SH, Callery MP, Meyers WC, et al. Regulation of NFkappaB in hepatic ischemic preconditioning. J Am Coll Surg 2002;195:319-326. (Pubitemid 35006285)
28. Xu MQ, Shuai XR, Yan ML, Zhang MM, Yan LN. Nuclear factor-kappaB decoy oligodeoxynucleotides attenuates ischemia/reperfusion injury in rat liver graft. World J Gastroenterol 2005;11:6960-6967.
29. Takahashi Y, Ganster RW, Ishikawa T, Okuda T, Gambotto A, Shao L, et al. Protective role of NF-kappaB in liver cold ischemia/reperfusion injury: effects of IkappaB gene therapy. Transplant Proc 2001;33:602. (Pubitemid 32237532)
30. Lentsch AB, Shanley TP, Sarma V, Ward PA. In vivo suppression of NF-kappa B and preservation of I kappa B alpha by interleukin-10 and interleukin-13. J Clin Invest 1997;100:2443-2448. (Pubitemid 27514883)