메뉴 건너뛰기




Volumn 70, Issue 7, 2010, Pages 689-700

Gestational and neonatal-onset hypothyroidism alters androgen receptor status in rat prostate glands at adulthood

Author keywords

AR lig and binding activity; AR mRNA; AR protein; Hypothyroidism; Methimazole

Indexed keywords

ANDROGEN RECEPTOR; ESTRADIOL; MESSENGER RNA; THIAMAZOLE; THYROID HORMONE; THYROTROPIN;

EID: 77951871021     PISSN: 02704137     EISSN: 10970045     Source Type: Journal    
DOI: 10.1002/pros.21101     Document Type: Article
Times cited : (18)

References (66)
  • 1
    • 0029087856 scopus 로고
    • Thyroid hormone and male gonadal function
    • Jannini EA, Ulisse S, D'Armiento M. Thyroid hormone and male gonadal function. Endocr Rev 1995;16:443-459.
    • (1995) Endocr Rev , vol.16 , pp. 443-459
    • Jannini, E.A.1    Ulisse, S.2    D'Armiento, M.3
  • 3
    • 77958176619 scopus 로고    scopus 로고
    • The male and female reproductive system in thyrotoxicosis
    • Braverman LE, Utiger RD, editors. Philadelphia: Lippincott Williams &Wilkins
    • Krassas GE. The male and female reproductive system in thyrotoxicosis. In: Braverman LE, Utiger RD, editors. Werner & Ingbar's the thyroid. Philadelphia: Lippincott Williams &Wilkins; 2005. pp 620-628.
    • (2005) Werner & Ingbar's the Thyroid , pp. 620-628
    • Krassas, G.E.1
  • 4
    • 77958176619 scopus 로고    scopus 로고
    • The male and female reproductive system in hypothyroidism
    • Braverman LE, Utiger RD, editors. Philadelphia: Lippincott Williams &Wilkins
    • Krassas GE. The male and female reproductive system in hypothyroidism. In: Braverman LE, Utiger RD, editors. Werner & Ingbar's the thyroid. Philadelphia: Lippincott Williams &Wilkins; 2005. pp 827-829.
    • (2005) Werner & Ingbar's the Thyroid , pp. 827-829
    • Krassas, G.E.1
  • 5
    • 0036481634 scopus 로고    scopus 로고
    • Adolescent thyroid disorders
    • Hanna CE, LaFranchi SH. Adolescent thyroid disorders. Adol Med 2002;13:13-36.
    • (2002) Adol Med , vol.13 , pp. 13-36
    • Hanna, C.E.1    LaFranchi, S.H.2
  • 6
    • 0000337805 scopus 로고
    • The thyroid
    • Kaplan S, editor. 2nd edition. Philadelphia, USA: WB Saunders Co.
    • Fisher D. The thyroid. In: Kaplan S, editor. Clinical pediatric endocrinology, 2nd edition. Philadelphia, USA: WB Saunders Co.; 1990. pp 87-126.
    • (1990) Clinical Pediatric Endocrinology , pp. 87-126
    • Fisher, D.1
  • 7
    • 0023858694 scopus 로고
    • Hypothalamic-pituitary gonadal axis in boys with primary hypothyroidism and macroorchidism
    • Castro-Magana M, Angulo M, Canas A, Sharp A, Fuentes B. Hypothalamic-pituitary gonadal axis in boys with primary hypothyroidism and macroorchidism. J Pediatr 1988;112:397-402. (Pubitemid 18079822)
    • (1988) Journal of Pediatrics , vol.112 , Issue.3 , pp. 397-402
    • Castro-Magana, M.1    Angulo, M.2    Canas, A.3    Sharp, A.4    Fuentes, B.5
  • 9
    • 0020035372 scopus 로고
    • Specific effect of the thyroid on testicular enzymes involved in carbohydrate metabolism. I. Hypothyroidism
    • Aruldhas MM, Valivullah HM, Govindarajulu P. Specific effect of the thyroid on testicular enzymes involved in carbohydrate metabolism I. Hypothyroidism. Int J Androl 1982;5:196-204. (Pubitemid 12125176)
    • (1982) International Journal of Andrology , vol.5 , Issue.2 , pp. 196-204
    • Aruldhas, M.M.1    Valivullah, H.M.2    Govindarajulu, P.3
  • 10
    • 0020328361 scopus 로고
    • Specific effect of thyroid on testicular enzymes involved in carbohydrate metabolism. II. Hyperthyroidism
    • Aruldhas MM, Valivullah HM, Govindarajulu P. Specific effect of thyroid on testicular enzymes involved in carbohydrate metabolism. II. Hyperthyroidism. Biochim Biophys Acta 1982;715:121-125.
    • (1982) Biochim Biophys Acta , vol.715 , pp. 121-125
    • Aruldhas, M.M.1    Valivullah, H.M.2    Govindarajulu, P.3
  • 11
    • 0020700189 scopus 로고
    • Effect of thyroidectomy on testicular enzymes of the pyruvate/malate cycle involved in lipogenesis
    • Aruldhas MM, Valivullah HM, Govindarajulu P. Effect of thyroidectomy on testicular enzymes of pyruvate/malate cycle involved in lipogenesis. Biochim Biophys Acta 1983;755:90-94. (Pubitemid 13156829)
    • (1983) Biochimica et Biophysica Acta , vol.755 , Issue.1 , pp. 90-94
    • Aruldhas, M.M.1    Valivullah, H.M.2    Govindarajulu, P.3
  • 12
    • 0021322510 scopus 로고
    • Effect of thyroxine-induced hyperthyroidism on some testicular enzymes of the pyruvate/malate cycle
    • DOI 10.1016/0304-4165(84)90115-6
    • Aruldhas MM, Valivullah HM, Govindarajulu P. Effect of thyroxine-induced hyperthyroidism on some testicular enzymes of the pyruvate/malate cycle. Biochim Biophys Acta 1984;797:143-146. (Pubitemid 14197626)
    • (1984) Biochimica et Biophysica Acta - General Subjects , vol.797 , Issue.2 , pp. 143-146
    • Aruldhas, M.M.1    Valivullah, H.M.2    Govindarajulu, P.3
  • 14
    • 0027263237 scopus 로고
    • Leydig cells increase their numbers but decline in steroidogenic function in the adult rat after neonatal hypothyroidism
    • Hardy MP, Kirby RA, Hess RA, Cooke PS. Leydig cells increase their numbers but decline in steroidogenic function in the adult rat after neonatal hypothyroidism. Endocrinology 1993;132:2417-2420.
    • (1993) Endocrinology , vol.132 , pp. 2417-2420
    • Hardy, M.P.1    Kirby, R.A.2    Hess, R.A.3    Cooke, P.S.4
  • 18
    • 0034978266 scopus 로고    scopus 로고
    • Impact of neonatal hypothyroidism on Leydig cell number, plasma, and testicular interstitial fluid sex steroids concentration
    • DOI 10.1081/ERC-100107175
    • Maran RRM, Ravichandran K, Arunakaran J, Aruldhas MM. Impact of neonatal hypothyroidism on Leydig cell number, plasma, and testicular interstitial fluid sex steroids concentration. Endocr Res 2001;27:119-141. (Pubitemid 32565583)
    • (2001) Endocrine Research , vol.27 , Issue.1-2 , pp. 119-141
    • Maran, R.R.M.1    Ravichandran, K.2    Arunakaran, J.3    Aruldhas, M.M.4
  • 23
    • 0021364424 scopus 로고
    • Thyroid epididymal relationship. II. Influence of hyperthyroidism on epididymal lipids
    • Pereira BMJ, Balasubramanian K, Govindarajulu P. Thyroid epididymal relationship. II. Influence of hyperthyroidism on epididymal lipids. Biochim Biophys Acta 1984;792:207-213.
    • (1984) Biochim Biophys Acta , vol.792 , pp. 207-213
    • Pereira, B.M.J.1    Balasubramanian, K.2    Govindarajulu, P.3
  • 24
    • 0028033669 scopus 로고
    • Influence of hypothyroidism induced at prepuberty on epididymal lipids and the number and motility of spermatozoa in rats
    • Senthilkumar PN, Aruldhas MM, Juneja HC. Influence of hypothyroidism-induced at prepuberty on epididymal lipids and the number and motility of spermatozoa in rats. Int J Androl 1995;17:262-270. (Pubitemid 24351553)
    • (1994) International Journal of Andrology , vol.17 , Issue.5 , pp. 262-270
    • Kumar, P.N.S.1    Aruldhas, M.M.2    Juneja, S.C.3
  • 29
    • 77951816089 scopus 로고
    • Effect of prepubertal hypothyroidism on some glycoprotein-associated monosaccharides in the seminal vesicles of Wistar rats
    • Senthilkumaran B, Manimaran RR, Shavali SS, Aruldhas MM, Govindarajulu P. Effect of prepubertal hypothyroidism on some glycoprotein-associated monosaccharides in the seminal vesicles of Wistar rats. Eur J Arch Biol 1993;103:251-255.
    • (1993) Eur J Arch Biol , vol.103 , pp. 251-255
    • Senthilkumaran, B.1    Manimaran, R.R.2    Shavali, S.S.3    Aruldhas, M.M.4    Govindarajulu, P.5
  • 34
    • 0023243367 scopus 로고
    • Thyroid hormone modulation of thyrotrophin-releasing hormone (TRH) and TRH-Gly levels in the male rat reproductive system
    • Pekary AE, Bhasin S, Smith R, Sugawaa M, Swerdloff RS, Hershman JM. Thyroid hormone modulation of thyrotropin-releasing hormone (TRH) and TRH-Gly levels in the male rat reproductive system. J Endocrinol 1987;114:271-277. (Pubitemid 17100013)
    • (1987) Journal of Endocrinology , vol.114 , Issue.2 , pp. 271-277
    • Pekary, A.E.1    Bhasin, S.2    Smith, V.3
  • 35
    • 18244400413 scopus 로고    scopus 로고
    • Cell growth effects of triiodothyronine and expression of thyroid hormone receptor in prostate carcinoma cells
    • DOI 10.2164/jandrol.04162
    • Hsieh ML, Juang HH. Cell growth effects of triiodothyronine and expression of thyroid hormone receptor in prostate carcinoma cells. J Androl 2005;26:422-428. (Pubitemid 40628980)
    • (2005) Journal of Andrology , vol.26 , Issue.3 , pp. 422-428
    • Hsieh, M.-L.1    Juang, H.-H.2
  • 36
    • 0028921940 scopus 로고
    • Triiodo thyronine modulates growth, secretory function and androgen receptor concentration in the prostatic carcinoma cell line LNCaP
    • Esquenet M, Swinnen JV, Heyns W, Verhoeven G. Triiodo thyronine modulates growth, secretory function and androgen receptor concentration in the prostatic carcinoma cell line LNCaP. Mol Cell Endocrinol 1995;109:105-111.
    • (1995) Mol Cell Endocrinol , vol.109 , pp. 105-111
    • Esquenet, M.1    Swinnen, J.V.2    Heyns, W.3    Verhoeven, G.4
  • 37
    • 0032982444 scopus 로고    scopus 로고
    • Interactive effects of triiodothyronine and androgens on prostate cell growth and gene expression
    • Zhang S, Hsieh ML, Zhu W, Klee GG, Tindall DJ, Young CYF. Interactive effects of tri-iodothyronine and androgens on prostate cell growth and gene expression. Endocrinology 1999;140:1665-1671. (Pubitemid 29149235)
    • (1999) Endocrinology , vol.140 , Issue.4 , pp. 1665-1671
    • Zhang, S.1    Hsieh, M.-L.2    Zhu, W.3    Klee, G.G.4    Tindall, D.J.5    Young, C.Y.F.6
  • 38
    • 0031056977 scopus 로고    scopus 로고
    • Neonatal hypothyroidism alters the pattern of prostatic growth and differentiation, as well as plasminogen activator and metalloprotease expression, in the rat
    • Wilson MJ, Kirby JD, Yi-dong ZY, Sinha AA, Cooke PS. Neonatal hypothyroidism alters the pattern of prostatic growth and differentiation, as well as plasminogen activator and metalloprotease expression, in the rat. Biol Reprod 1997;56:475-482.
    • (1997) Biol Reprod , vol.56 , pp. 475-482
    • Wilson, M.J.1    Kirby, J.D.2    Yi-dong, Z.Y.3    Sinha, A.A.4    Cooke, P.S.5
  • 40
    • 0025751540 scopus 로고
    • Androgen receptor localization in different cell types of the adult rat prostate
    • Prins G, Birch L, Green G. Androgen receptor localization in different cell types of the adult rat prostate. Endocrinology 1991;129:3187-3199.
    • (1991) Endocrinology , vol.129 , pp. 3187-3199
    • Prins, G.1    Birch, L.2    Green, G.3
  • 41
    • 1942437976 scopus 로고    scopus 로고
    • Estrogenic Regulation of Signaling Pathways and Homeobox Genes during Rat Prostate Development
    • Huang L, Pu Y, Alam S, Birch L, Prins GS. Estrogenic regulation of signalling pathways and homeobox genes during rat prostate development. J Androl 2004;25:330-399. (Pubitemid 38509228)
    • (2004) Journal of Andrology , vol.25 , Issue.3 , pp. 330-337
    • Huang, L.1    Pu, Y.2    Alam, S.3    Birch, L.4    Prins, G.S.5
  • 42
    • 0015396017 scopus 로고
    • The thyroid accumulation, oxidation and metabolic rate of 35 S-methimazole in rat
    • Marchant B, Alexander WD. The thyroid accumulation, oxidation and metabolic rate of 35 S-methimazole in rat. Endocrinology 1972;91:747-752.
    • (1972) Endocrinology , vol.91 , pp. 747-752
    • Marchant, B.1    Alexander, W.D.2
  • 43
    • 77951848105 scopus 로고
    • The pharmacological basis of therapeutics
    • Gillman AG, Rall TW, Nies AS, Tatlor P, editors. 8th edition. Singapore: Pergamon Press
    • Haynes RCJ. The pharmacological basis of therapeutics. In: Gillman AG, Rall TW, Nies AS, Tatlor P, editors. Thyroid and antithyroid drugs, 8th edition. Singapore: Pergamon Press; 1991. pp 1373-1375.
    • (1991) Thyroid and Antithyroid Drugs , pp. 1373-1375
    • Haynes, R.C.J.1
  • 44
    • 0026798795 scopus 로고
    • Induction of increased testis growth and sperm production in adult rats by neonatal administration of the goitrogen propylthiouracil (PTU): The critical period
    • Cooke PS, Porcelli J, Hess RA. Induction of increased testis growth and sperm production in adult rats by neonatal administration of the goitrogen propylthiouracil (PTU): The critical period. Biol Reprod 1992;46:146-154.
    • (1992) Biol Reprod , vol.46 , pp. 146-154
    • Cooke, P.S.1    Porcelli, J.2    Hess, R.A.3
  • 45
    • 0036144989 scopus 로고    scopus 로고
    • Developmental profiles of TSH, sex steroids, and their receptors in the thyroid and their relevance to thyroid growth in immature rats
    • DOI 10.1016/S0039-128X(01)00144-1, PII S0039128X01001441
    • Banu SK, Govindarajulu P, Aruldhas MM. Developmental profiles of TSH, sex steroids and their receptors in the thyroid and their relevance to thyroid growth in immature rats. Steroids 2002;67:137-144. (Pubitemid 34081832)
    • (2002) Steroids , vol.67 , Issue.2 , pp. 137-144
    • Banu, S.K.1    Govindarajulu, P.2    Aruldhas, M.M.3
  • 46
    • 0037230126 scopus 로고    scopus 로고
    • Modulatory effect of estradiol and testosterone on the development of N-nitrosodiisopropanolamine induced thyroid tumors in female rats
    • DOI 10.1081/ERC-120018675
    • Thiruvengadam A, Govindarajulu P, Aruldhas MM. Modulatory effect of estradiol and testosterone on the development of nitrosodiisopropanolamine induced thyroid tumors in female rats. Endocrine Res 2003;29:43-51. (Pubitemid 36337409)
    • (2003) Endocrine Research , vol.29 , Issue.1 , pp. 43-51
    • Thiruvengadam, A.1    Govindarajulu, P.2    Aruldhas, M.M.3
  • 47
    • 0042770258 scopus 로고
    • Structural analysis of complementary DNA and aminoacid sequences of the human and rat androgen receptors
    • Chang C, Kokontis J, Liao S. Structural analysis of complementary DNA and aminoacid sequences of the human and rat androgen receptors. Proc Natl Acad Sci USA 1988;85:7211-7215.
    • (1988) Proc Natl Acad Sci USA , vol.85 , pp. 7211-7215
    • Chang, C.1    Kokontis, J.2    Liao, S.3
  • 48
    • 0023102943 scopus 로고
    • The primary structure of rat ribosomal protein L19. a determination from the sequence of nucleotides in a cDNA and from the sequence of amino acids in the protein
    • Chan YL, Lin A, McNally J, Peleg D, Meyuhas O, Wool IG. The primary structure of rat ribosomal protein L19. A determination from the sequence of nucleotides in a cDNA and from the sequence of amino acids in the protein. J Biol Chem 1987;262:1111-1115. (Pubitemid 17028421)
    • (1987) Journal of Biological Chemistry , vol.262 , Issue.3 , pp. 1111-1115
    • Chan, Y.-L.1    Lin, A.2    McNally, J.3
  • 51
    • 0020146162 scopus 로고
    • Androgen-dependent regulation of androgen nuclear receptor in the rat ventral prostate
    • Blondeau JP, Baulieu EE, Robel P. Androgen-dependent regulation of androgen nuclear receptor in the rat ventral prostate. Endocrinology 1982;110:1926-1932.
    • (1982) Endocrinology , vol.110 , pp. 1926-1932
    • Blondeau, J.P.1    Baulieu, E.E.2    Robel, P.3
  • 52
    • 0021915114 scopus 로고
    • Mechanism of androgen-receptor augmentation. Analysis of receptor synthesis and degradation by the density-shift technique
    • Syms AJ, Norris JS, Panko WB, Smith RG. Mechanism of androgen-receptor augmentation. Analysis of receptor synthesis and degradation by the density-shift technique. J Biol Chem 1985;260:455-461.
    • (1985) J Biol Chem , vol.260 , pp. 455-461
    • Syms, A.J.1    Norris, J.S.2    Panko, W.B.3    Smith, R.G.4
  • 53
    • 0026645949 scopus 로고
    • Regulation of androgen receptor by androgen and epidermal growth factor in a human prostatic cancer cell line, LNCaP
    • Mizokami A, Saiga H, Matsui T, Mita T, Sugita A. Regulation of androgen receptor by androgen and epidermal growth factor in a human prostatic cancer cell line, LNCaP. Endocrinology 1992;39:235-243.
    • (1992) Endocrinology , vol.39 , pp. 235-243
    • Mizokami, A.1    Saiga, H.2    Matsui, T.3    Mita, T.4    Sugita, A.5
  • 56
    • 0027214174 scopus 로고
    • Transcriptional and posttranscriptional regulation of human androgen receptor expression by androgen
    • DOI 10.1210/me.7.7.924
    • Wolf DA, Herzinger T, Hermeking H, Blaschke D, Horz W. Transcriptional and posttranscriptional regulation of human androgen receptor expression by androgen. Mol Endocrinol 1993;7:924-936. (Pubitemid 23220643)
    • (1993) Molecular Endocrinology , vol.7 , Issue.7 , pp. 924-936
    • Wolf, D.A.1    Herzinger, T.2    Hermeking, H.3    Blaschke, D.4    Horz, W.5
  • 57
    • 0029041681 scopus 로고
    • Identification of three proline directed phosphorylation sites in the human androgen receptor
    • Zhou ZX, Kemppainen JA, Wilson EM. Identification of three proline directed phosphorylation sites in the human androgen receptor. Mol Endocrinol 1995;9:605-615.
    • (1995) Mol Endocrinol , vol.9 , pp. 605-615
    • Zhou, Z.X.1    Kemppainen, J.A.2    Wilson, E.M.3
  • 59
    • 0018760437 scopus 로고
    • Effects of neonatal steroids on male sex tissues
    • Rajfer J, Coffey DS. Effects of neonatal steroids on male sex tissues. Invest Urol 1979;17:3-8. (Pubitemid 9239411)
    • (1979) Investigative Urology , vol.17 , Issue.1 , pp. 3-8
    • Rajfer, J.1    Coffey, D.S.2
  • 60
    • 0023025045 scopus 로고
    • The differential effects of neonatal androgen, estrogen and progesterone on adult rat prostate growth
    • Naslund MJ, Coffey DS. The differential effects of neonatal androgen, estrogen and progesterone on adult rat prostate growth. J Urol 1986;136:1136-1140.
    • (1986) J Urol , vol.136 , pp. 1136-1140
    • Naslund, M.J.1    Coffey, D.S.2
  • 61
    • 0026767048 scopus 로고
    • Neonatal estrogen exposure induces lobe-specific alterations in adult rat prostate androgen receptor expression
    • Prins GS. Neonatal estrogen exposure induces lobe-specific alterations in adult rat prostate androgen receptor expression. Endocrinology 1992;130:3703-3714.
    • (1992) Endocrinology , vol.130 , pp. 3703-3714
    • Prins, G.S.1
  • 62
    • 0027245474 scopus 로고
    • Effects of neonatal estrogen exposure on prostatic secretory genes and their correlation with androgen receptor expression in the separate prostate lobes of the adult rat
    • DOI 10.1210/en.132.6.2387
    • Prins GS, Woodham C, Lepinske M, Birch L. Effects of neonatal estrogen exposure on prostatic secretory genes and their correlation with androgen receptor expression in the separate prostate lobes of the adult rat. Endocrinology 1993;132:2387-2398. (Pubitemid 23156886)
    • (1993) Endocrinology , vol.132 , Issue.6 , pp. 2387-2398
    • Prins, G.S.1    Woodham, C.2    Lepinske, M.3    Birch, L.4
  • 63
    • 0242636833 scopus 로고    scopus 로고
    • Neonatal Estrogen Down-Regulates Prostatic Androgen Receptor through a Proteosome-Mediated Protein Degradation Pathway
    • DOI 10.1210/en.2003-0035
    • Woodham C, Birch L, Prins GS. Neonatal estrogen downregulates prostatic androgen receptor through a proteosome mediated protein degradation pathway. Endocrinology 2003;144:4841-4850. (Pubitemid 37378399)
    • (2003) Endocrinology , vol.144 , Issue.11 , pp. 4841-4850
    • Woodham, C.1    Birch, L.2    Prins, G.S.3
  • 64
    • 0026700723 scopus 로고
    • Growth hormone and prolactin stimulate androgen receptor, insulin-like growth factor-1 (IGF-1) and IGF-1 receptor levels in the prostate of immature rats
    • Reiter E, Bonnet P, Sente B, Dombrowicz D, De Leval J, Closset J, Henen G. Growth hormone and prolactin stimulate androgen receptor, insulin-like growth factor-1 (IGF-1) and IGF-1 receptor levels in the prostate of immature rats. Mol Cell Endocrinol 1992;88:77-87.
    • (1992) Mol Cell Endocrinol , vol.88 , pp. 77-87
    • Reiter, E.1    Bonnet, P.2    Sente, B.3    Dombrowicz, D.4    De Leval, J.5    Closset, J.6    Henen, G.7
  • 65
    • 0023092546 scopus 로고
    • Prolactin influence on cytosol and nuclear androgen receptors in the ventral, dorsal and lateral lobes of the rat prostate
    • Prins GS. Prolactin influence on cytosol and nuclear androgen receptors in the ventral, dorsal and lateral lobes of the rat prostate. Endocrinology 1987;120:1457-1464.
    • (1987) Endocrinology , vol.120 , pp. 1457-1464
    • Prins, G.S.1
  • 66
    • 84912262495 scopus 로고
    • Text Book of Endocrinology
    • Hafez ESE, Evans TN, editors. Hagerstown: Harper and Row publishers
    • Amelar RD, Dubin L. Text Book of Endocrinology. In: Hafez ESE, Evans TN, editors. Human reproduction-conception and contraception. Hagerstown: Harper and Row publishers; 1973. pp 645-651.
    • (1973) Human Reproduction-conception and Contraception , pp. 645-651
    • Amelar, R.D.1    Dubin, L.2


* 이 정보는 Elsevier사의 SCOPUS DB에서 KISTI가 분석하여 추출한 것입니다.