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1
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70349338789
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The interface of medicare coverage decisionmaking and emerging molecular-based laboratory testing
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Burken MI, Wilson KS, Heller K, Pratt VM, Schoonmaker MM, Seifter E: The interface of medicare coverage decisionmaking and emerging molecular-based laboratory testing. Genet. Med. 11 (4), 225-231 (2009).
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(2009)
Genet. Med.
, vol.11
, Issue.4
, pp. 225-231
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Burken, M.I.1
Wilson, K.S.2
Heller, K.3
Pratt, V.M.4
Schoonmaker, M.M.5
Seifter, E.6
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2
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36448942960
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A critical analysis of barriers to the clinical implementation of pharmacogenomics
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Mckinnon RA, Ward MB, Sorich MJ: A critical analysis of barriers to the clinical implementation of pharmacogenomics. Ther. Clin. Risk Manag. 3 (5), 751-759 (2007). (Pubitemid 350162075)
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(2007)
Therapeutics and Clinical Risk Management
, vol.3
, Issue.5
, pp. 751-759
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McKinnon, R.A.1
Ward, M.B.2
Sorich, M.J.3
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3
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73449139146
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Pharmaceutical industry financial performance
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Goodman M: Pharmaceutical industry financial performance. Nat. Rev. Drug Discov. 8 (12), 927-928 (2009).
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(2009)
Nat. Rev. Drug Discov.
, vol.8
, Issue.12
, pp. 927-928
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Goodman, M.1
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4
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67649979950
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Personalized medicine: A paradigm for a sustainable pharmaceutical industry?
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Chackalamannil S, Desai MC: Personalized medicine: a paradigm for a sustainable pharmaceutical industry? Curr. Opin. Drug Discov. Devel. 12 (4), 443-445 (2009).
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(2009)
Curr. Opin. Drug Discov. Devel.
, vol.12
, Issue.4
, pp. 443-445
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Chackalamannil, S.1
Desai, M.C.2
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5
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77951454005
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Myriad genetics: In the eye of the policy storm
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Gold ER, Carbone J: Myriad Genetics: in the eye of the policy storm. Genet. Med. 12 (4), S39-S70 (2010).
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(2010)
Genet. Med.
, vol.12
, Issue.4
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Gold, E.R.1
Carbone, J.2
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6
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77951824964
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Striking discussion of how different countries have developed diverse policy approaches to genetic patents
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Striking discussion of how different countries have developed diverse policy approaches to genetic patents.
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7
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64549116875
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Pharmacogenomics, evidence, and the role of payers
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Deverka PA: Pharmacogenomics, evidence, and the role of payers. Public Health Genomics 12 (3), 149-157 (2009).
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(2009)
Public Health Genomics
, vol.12
, Issue.3
, pp. 149-157
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Deverka, P.A.1
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8
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70349958160
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The paradox of equipoise: The principle that drives and limits discoveries in clinical research
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Djulbegovic B: The paradox of equipoise: the principle that drives and limits discoveries in clinical research. Cancer Control 16 (4), 342-347 (2009).
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(2009)
Cancer Control.
, vol.16
, Issue.4
, pp. 342-347
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Djulbegovic, B.1
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9
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77951835676
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Expands on this article's discussion of clinical equipoise and contains an excellent bibliography
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Expands on this article's discussion of clinical equipoise and contains an excellent bibliography.
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11
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26844470894
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The randomized controlled trial: Gold standard, or merely standard?
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Grossman J, MacKenzie FJ: The randomized controlled trial: gold standard, or merely standard? Perspect. Biol. Med. 48 (4), 516-534 (2005). (Pubitemid 41464107)
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(2005)
Perspectives in Biology and Medicine
, vol.48
, Issue.4
, pp. 516-534
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Grossman, J.1
Mackenzie, F.J.2
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13
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77951833510
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Best comprehensive book on the potential pitfalls that are found among the advantages of the evidence-based medicine approach
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Best comprehensive book on the potential pitfalls that are found among the advantages of the evidence-based medicine approach.
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14
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55949116238
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Evaluating the evidence: Is there a rigid hierarchy?
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Ho PM, Peterson PN, Masoudi FA: Evaluating the evidence: is there a rigid hierarchy? Circulation 118 (16), 1675-1684 (2008).
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(2008)
Circulation
, vol.118
, Issue.16
, pp. 1675-1684
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Ho, P.M.1
Peterson, P.N.2
Masoudi, F.A.3
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15
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77951788269
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Good presentation of reasons why the evidence hierarchy should not be taken as an automatic good
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Good presentation of reasons why the evidence hierarchy should not be taken as an automatic good.
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16
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70349939382
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Biomarkers predicting clinical outcome of epidermal growth factor receptor-targeted therapy in metastatic colorectal cancer
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Siena S, Sartore-Bianchi A, Di Nicolantonio F, Balfour J, Bardelli A: Biomarkers predicting clinical outcome of epidermal growth factor receptor-targeted therapy in metastatic colorectal cancer. J. Natl Cancer Inst. 101 (19), 1308-1324 (2009).
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(2009)
J. Natl. Cancer Inst.
, vol.101
, Issue.19
, pp. 1308-1324
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Siena, S.1
Sartore-Bianchi, A.2
Nicolantonio, F.D.3
Balfour, J.4
Bardelli, A.5
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17
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37349116252
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The continuum of translation research in genomic medicine: How can we accelerate the appropriate integration of human genome discoveries into health care and disease prevention?
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DOI 10.1097/GIM.0b013e31815699d0, PII 0012581720071000000001
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Khoury MJ, Gwinn M, Yoon PW, Dowling N, Moore CA, Bradley L: The continuum of translation research in genomic medicine: how can we accelerate the appropriate integration of human genome discoveries into health care and disease prevention? Genet. Med. 9 (10), 665-674 (2007). (Pubitemid 350287151)
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(2007)
Genetics in Medicine
, vol.9
, Issue.10
, pp. 665-674
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Khoury, M.J.1
Gwinn, M.2
Yoon, P.W.3
Dowling, N.4
Moore, C.A.5
Bradley, L.6
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18
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68249130994
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Rethinking randomized clinical trials for comparative effectiveness research: The need for transformational change
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Luce BR, Kramer JM, Goodman SN et al.: Rethinking randomized clinical trials for comparative effectiveness research: the need for transformational change. Ann. Intern. Med. 151 (3), 206-209 (2009).
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(2009)
Ann. Intern. Med.
, vol.151
, Issue.3
, pp. 206-209
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Luce, B.R.1
Kramer, J.M.2
Goodman, S.N.3
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19
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65649121473
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Does comparativeeffectiveness research threaten personalized medicine?
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Garber AM, Tunis SR: Does comparativeeffectiveness research threaten personalized medicine? N. Engl. J. Med. 360 (19), 1925-1927 (2009).
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(2009)
N. Engl. J. Med.
, vol.360
, Issue.19
, pp. 1925-1927
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Garber, A.M.1
Tunis, S.R.2
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20
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57649198083
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De testimonio: On the evidence for decisions about the use of therapeutic interventions
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Rawlins M: De testimonio: on the evidence for decisions about the use of therapeutic interventions. Lancet 372 (9656), 2152-2161 (2008).
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(2008)
Lancet
, vol.372
, Issue.9656
, pp. 2152-2161
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Rawlins, M.1
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21
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77951773898
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Outstanding article discussing the gaps between evidence review and the ultimate decisions of payment agencies
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Outstanding article discussing the gaps between evidence review and the ultimate decisions of payment agencies.
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22
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34547222697
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Study designs for effectiveness and translation research: Identifying trade-offs
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DOI 10.1016/j.amepre.2007.04.005, PII S0749379707002152
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Mercer SL, Devinney BJ, Fine LJ, Green LW, Dougherty D: Study designs for effectiveness and translation research: identifying trade-offs. Am. J. Prev. Med. 33 (2), 139-154 (2007). (Pubitemid 47161054)
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(2007)
American Journal of Preventive Medicine
, vol.33
, Issue.2
, pp. 139-154
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Mercer, S.L.1
DeVinney, B.J.2
Fine, L.J.3
Green, L.W.4
Dougherty, D.5
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23
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77951844678
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Example of the increasingly academic and intellectually rigorous approach to extrapolating from clinical trials to clinical practice. This will be increasingly important when the evidence is from retrospective genomic trials
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Example of the increasingly academic and intellectually rigorous approach to extrapolating from clinical trials to clinical practice. This will be increasingly important when the evidence is from retrospective genomic trials.
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24
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77952295734
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How to assess the external validity of therapeutic trials: A conceptual approach
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Dekkers OM, von Elm E, Algra A, Romijn JA, Vandenbroucke JP: How to assess the external validity of therapeutic trials: a conceptual approach. Int. J. Epidemiol. 39 (1), 89-94 (2010).
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(2010)
Int. J. Epidemiol
, vol.39
, Issue.1
, pp. 89-94
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Dekkers, O.M.1
Von Elm, E.2
Algra, A.3
Romijn, J.A.4
Vandenbroucke, J.P.5
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25
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77951822307
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Example of the increasingly academic and intellectually rigorous approach to extrapolating from clinical trials to clinical practice. This will be increasingly important when the evidence is from retrospective genomic trials
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Example of the increasingly academic and intellectually rigorous approach to extrapolating from clinical trials to clinical practice. This will be increasingly important when the evidence is from retrospective genomic trials.
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26
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34247530125
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Factors that can affect the external validity of randomised controlled trials
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Rothwell PM: Factors that can affect the external validity of randomised controlled trials. PLoS Clin. Trials 1 (1), E9 (2006).
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(2006)
PLoS Clin. Trials
, vol.1
, Issue.1
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Rothwell, P.M.1
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27
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77951803897
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Example of the increasingly academic and intellectually rigorous approach to extrapolating from clinical trials to clinical practice. This will be increasingly important when the evidence is from retrospective genomic trials
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Example of the increasingly academic and intellectually rigorous approach to extrapolating from clinical trials to clinical practice. This will be increasingly important when the evidence is from retrospective genomic trials.
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28
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74049084937
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Assessing lead time of selected ovarian cancer biomarkers: A nested case-control study
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Anderson GL, Mcintosh M, Wu L et al.: Assessing lead time of selected ovarian cancer biomarkers: a nested case-control study. J. Natl Cancer Inst. 102 (1), 26-38 (2010).
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(2010)
J. Natl. Cancer Inst.
, vol.102
, Issue.1
, pp. 26-38
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Anderson, G.L.1
Mcintosh, M.2
Wu, L.3
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29
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70449420123
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Use of archived specimens in evaluation of prognostic and predictive biomarkers
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Simon RM, Paik S, Hayes DF: Use of archived specimens in evaluation of prognostic and predictive biomarkers. J. Natl. Cancer Inst. 101 (21), 1446-1452 (2009).
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(2009)
J. Natl. Cancer Inst.
, vol.101
, Issue.21
, pp. 1446-1452
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Simon, R.M.1
Paik, S.2
Hayes, D.F.3
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31
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77951872988
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Excellent textbook on evaluating the medical literature, and distinctive in its segregation of therapeutic trials from diagnostic test trials
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Excellent textbook on evaluating the medical literature, and distinctive in its segregation of therapeutic trials from diagnostic test trials.
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