Histiocytic sarcoma arising in indolent small B-cell lymphoma: Report of two cases with molecular/genetic evidence suggestive of a 'transdifferentiation' during the clonal evolution

Leukemia and Lymphoma

Volumn 51, Issue 5, 2010, Pages 802-812

  Wang, Endi ^a   Hutchinson, Charles Blake ^a   Huang, Qin ^b   Sebastian, Siby ^a   Rehder, Catherine ^a   Kanaly, Angela ^a   Moore, Joseph ^a   Dato, Michael ^a  

^a DUKE UNIVERSITY MEDICAL CENTER   (United States)

^b CITY OF HOPE NATIONAL MEDICAL CENTER   (United States)

Author keywords

B cell lymphoma; Clonal relationship; Histiocytic sarcoma; Transdifferentiation

Indexed keywords

CYCLOPHOSPHAMIDE; DOXORUBICIN; IMMUNOGLOBULIN HEAVY CHAIN; OCTAMER TRANSCRIPTION FACTOR 2; PREDNISOLONE; PREDNISONE; PROTEIN BCL 2; PROTEIN BCL 6; RITUXIMAB; VINCRISTINE;

ABDOMINAL PAIN; ADULT; ANEMIA; ARTICLE; B CELL LYMPHOMA; BONE MARROW BIOPSY; CASE REPORT; CELL TRANSDIFFERENTIATION; CLONE; ERYTHROCYTE CONCENTRATE; FEMALE; FLUORESCENCE IN SITU HYBRIDIZATION; FOLLICULAR LYMPHOMA; GENE FUSION; GENE REARRANGEMENT; HEMATOMA; HISTIOCYTIC SARCOMA; HUMAN; HUMAN TISSUE; INGUINAL LYMPH NODE; LYMPHADENOPATHY; MOLECULAR GENETICS; MULTIPLE CYCLE TREATMENT; NIGHT SWEAT; NUCLEOTIDE SEQUENCE; POLYMERASE CHAIN REACTION; PRIORITY JOURNAL; PROTEIN EXPRESSION; SEQUENCE ANALYSIS; SPLEEN RUPTURE; SPLENIC MARGINAL ZONE LYMPHOMA; SPLENOMEGALY; WEAKNESS;

CELL TRANSDIFFERENTIATION; CLONE CELLS; DENDRITIC CELLS, FOLLICULAR; FEMALE; FLOW CYTOMETRY; GENE REARRANGEMENT, B-LYMPHOCYTE; GENES, BCL-2; HISTIOCYTIC SARCOMA; HUMANS; IMMUNOENZYME TECHNIQUES; IMMUNOGLOBULIN HEAVY CHAINS; IN SITU HYBRIDIZATION, FLUORESCENCE; LYMPHOMA, B-CELL; LYMPHOMA, FOLLICULAR; MIDDLE AGED; POLYMERASE CHAIN REACTION; PROGNOSIS;

EID: 77951849393     PISSN: 10428194     EISSN: 10292403     Source Type: Journal    
DOI: 10.3109/10428191003699845     Document Type: Article

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