Biological applications of fluorescence lifetime imaging beyond microscopy

Progress in Biomedical Optics and Imaging - Proceedings of SPIE

Volumn 7576, Issue , 2010, Pages

  Akers, Walter J ^a   Berezin, Mikhail Y ^a   Lee, Hyeran ^a   Guo, Kevin ^a   Almutairi, Adah ^b   Fréchet, Jean M J ^c   Fischer, Georg M ^d   Daltrozzo, Ewald ^d   Achilefu, Samuel ^a,e  

^a WASHINGTON UNIVERSITY SCHOOL OF MEDICINE   (United States)

^b UNIVERSITY OF CALIFORNIA SAN DIEGO   (United States)

^c UNIVERSITY OF CALIFORNIA   (United States)

^d UNIVERSITY OF KONSTANZ   (Germany)

^e WASHINGTON UNIVERSITY SCHOOL OF MEDICINE   (United States)

Author keywords

Molecular; Near infrared; Optical; Preclinical; Time resolved

Indexed keywords

BIOLOGICAL APPLICATIONS; CANCER BIOLOGY; CLINICAL APPLICATION; CONCENTRATION-DEPENDENT; CONTRAST AGENT; CONTRAST MECHANISM; CONTROLLED DRUG RELEASE; DEEP TISSUE IMAGING; DIFFUSE OPTICAL IMAGING; EXCITING FIELD; FLUORESCENCE LIFETIME IMAGING; FLUORESCENCE LIFETIME IMAGING MICROSCOPY; FLUORESCENCE LIFETIMES; FLUORESCENCE SIGNALS; FREQUENCY DOMAINS; FUTURE APPLICATIONS; HEALTHY TISSUES; IN-VITRO; IN-VIVO; INTENSITY-BASED; INTRINSIC FLUORESCENCE; INTRINSIC PROPERTY; LIVING ANIMALS; LIVING TISSUES; NEAR INFRARED; NEAR-INFRARED WAVELENGTH; OPTICAL IMAGING; PHYSIOLOGIC FUNCTION; PROTEIN-PROTEIN INTERACTIONS; TIME-RESOLVED;

ANIMALS; FLUOROPHORES; HISTOLOGY; INFRARED DEVICES; NANOPARTICLES; OPTICAL IMAGE STORAGE; PROBES; PROTEINS;

OPTICAL PROPERTIES;

EID: 77951837595     PISSN: 16057422     EISSN: None     Source Type: Conference Proceeding    
DOI: 10.1117/12.849453     Document Type: Conference Paper

References (38)

1. Coons, A. H., "The Beginnings of Immunofluorescence," J Immunol, 87(5), 499-503 (1961).
2. Wu, A. M., and Olafsen, T., "Antibodies for molecular imaging of cancer," Cancer J, 14(3), 191-197 (2008).
3. Achilefu, S., "Lighting up tumors with receptor-specific optical molecular probes," Technol Cancer Res Treat, 3(4), 393-409 (2004). (Pubitemid 39096612)
4. Greish, K., "Enhanced permeability and retention of macromolecular drugs in solid tumors: a royal gate for targeted anticancer nanomedicines," J Drug Target, 15(7-8), 457-464 (2007). (Pubitemid 47209047)
5. Chen, J. Q., Tung, C. H., Mahmood, U. et al., "In vivo imaging of proteolytic activity in atherosclerosis," Circulation, 105(23), 2766-2771 (2002). (Pubitemid 34615149)
6. Eckelman, W. C., and Mathis, C. A., "Targeting proteins in vivo: in vitro guidelines," Nucl Med Biol, 33(2), 161-164 (2006).
7. Frangioni, J. V., "The problem is background, not signal," Mol Imaging, 8(6), 303-304 (2009).
8. Suhling, K., French, P. M., and Phillips, D., "Time-resolved fluorescence microscopy," Photochem Photobiol Sci, 4(1), 13-22 (2005).
9. Tadrous, P. J., Siegel, J., French, P. M. et al., "Fluorescence lifetime imaging of unstained tissues: early results in human breast cancer," J Pathol, 199(3), 309-317 (2003). (Pubitemid 36266853)
10. Schweitzer, D., Hammer, M., Schweitzer, F. et al., "In vivo measurement of time-resolved autofluorescence at the human fundus," Journal of Biomedical Optics, 9(6), 1214-1222 (2004). (Pubitemid 40168136)
11. Galletly, N. P., McGinty, J., Dunsby, C. et al., "Fluorescence lifetime imaging distinguishes basal cell carcinoma from surrounding uninvolved skin," Br J Dermatol, 159(1), 152-161 (2008). (Pubitemid 351874465)
12. Villalobos, V., Naik, S., and Piwnica-Worms, D., "Current state of imaging protein-protein interactions in vivo with genetically encoded reporters," Annu Rev Biomed Eng, 9, 321-349 (2007). (Pubitemid 350246660)
13. Jares-Erijman, E. A., and Jovin, T. M., "FRET imaging," Nat Biotechnol, 21(11), 1387-1395 (2003).
14. Levitt, J. A., Matthews, D. R., Ameer-Beg, S. M. et al., "Fluorescence lifetime and polarization-resolved imaging in cell biology," Curr Opin Biotechnol, 20(1), 28-36 (2009).
15. Soloviev, V. Y., Tahir, K. B., McGinty, J. et al., "Fluorescence lifetime imaging by using time-gated data acquisition," Appl Opt, 46(30), 7384-7391 (2007).
16. Reynolds, J. S., Troy, T. L., Mayer, R. H. et al., "Imaging of spontaneous canine mammary tumors using fluorescent contrast agents," Photochem Photobiol, 70(1), 87-94 (1999).
17. Nothdurft, R. E., Patwardhan, S. V., Akers, W. J. et al., "Fluorescence Lifetime Tomography for Whole Body Small Animal Imaging."
18. Kumar, A. T., Raymond, S. B., Dunn, A. K. et al., "A time domain fluorescence tomography system for small animal imaging," IEEE Trans Med Imaging, 27(8), 1152-1163 (2008).
19. Godavarty, A., Sevick-Muraca, E. M., and Eppstein, M. J., "Three-dimensional fluorescence lifetime tomography," Med Phys, 32(4), 992-1000 (2005).
20. McGinty, J., Soloviev, V. Y., Tahir, K. B. et al., "Three- dimensional imaging of Forster resonance energy transfer in heterogeneous turbid media by tomographic fluorescent lifetime imaging," Opt Lett, 34(18), 2772-2774 (2009).
21. Cubeddu, R., Canti, G., Pifferi, A. et al., "Fluorescence lifetime imaging of experimental tumors in hematoporphyrin derivative-sensitized mice," Photochem Photobiol, 66(2), 229-236 (1997). (Pubitemid 127470171)
22. Andersson-Engels, S., Canti, G., Cubeddu, R. et al., "Preliminary evaluation of two fluorescence imaging methods for the detection and the delineation of basal cell carcinomas of the skin," Lasers Surg Med, 26(1), 76-82 (2000). (Pubitemid 30054275)
23. Berezin, M. Y., Lee, H., Akers, W. et al., "Near infrared dyes as lifetime solvatochromic probes for micropolarity measurements of biological systems," Biophys J, 93(8), 2892-2899 (2007). (Pubitemid 47607825)
24. Berezin, M. Y., Akers, W. J., Guo, K. et al., "Long Fluorescence Lifetime Molecular Probes Based on Near Infrared Pyrrolopyrrole Cyanine Fluorophores for In Vivo Imaging," Biophysical Journal, 97(9), L22-L24 (2009).
25. Almutairi, A., Akers, W. J., Berezin, M. Y. et al., "Monitoring the Biodegradation of Dendritic Near-Infrared Nanoprobes by in Vivo Fluorescence Imaging," Mol Pharm, (2008).
26. Akers, W. J., Berezin, M. Y., Lee, H. et al., "Predicting in vivo fluorescence lifetime behavior of near-infrared fluorescent contrast agents using in vitro measurements," J Biomed Opt, 13(5), 054042 (2008).
27. de la Zerda, A., Bodapati, S., Teed, R. et al., "A Comparison Between Time Domain and Spectral Imaging Systems for Imaging Quantum Dots in Small Living Animals," Mol Imaging Biol, (2009).
28. Keren, S., Gheysens, O., Levin, C. S. et al., "A comparison between a time domain and continuous wave small animal optical imaging system," IEEE Trans Med Imaging, 27(1), 58-63 (2008).
29. Akers, W., Lesage, F., Holten, D. et al., "In vivo resolution of multiexponential decays of multiple near-infrared molecular probes by fluorescence lifetime-gated whole-body time-resolved diffuse optical imaging," Mol Imaging, 6(4), 237-246 (2007). (Pubitemid 47509828)
30. Berezin, M. Y., Akers, W. J., Guo, K. et al., "Long fluorescence lifetime molecular probes based on near infrared pyrrolopyrrole cyanine fluorophores for in vivo imaging," Biophys J, 97(9), L22-4 (2009).
31. Berezin, M. Y., Lee, H., Akers, W. et al., "Engineering NIR dyes for fluorescent lifetime contrast," Conf Proc IEEE Eng Med Biol Soc, 1, 114-117 (2009).
32. Berezin, M. Y., Lee, H., Akers, W. et al., "Ratiometric analysis of fluorescence lifetime for probing binding sites in albumin with near-infrared fluorescent molecular probes," Photochem Photobiol, 83(6), 1371-1378 (2007). (Pubitemid 350132604)
33. Almutairi, A., Akers, W. J., Berezin, M. Y. et al., "Monitoring the biodegradation of dendritic near-infrared nanoprobes by in vivo fluorescence imaging," Mol Pharm, 5(6), 1103-1110 (2008).
34. Goiffon, R. J., Akers, W. J., Berezin, M. Y. et al., "Dynamic noninvasive monitoring of renal function in vivo by fluorescence lifetime imaging," J Biomed Opt, 14(2), 020501 (2009).
35. Akers, W. J., Berezin, M. Y., Lee, H. et al., "In vivo imaging with near-infrared fluorescence lifetime contrast." 7190, 71900T-8.
36. Ogawa, M., Kosaka, N., Choyke, P. L. et al., "In vivo molecular imaging of cancer with a quenching near-infrared fluorescent probe using conjugates of monoclonal antibodies and indocyanine green," Cancer Res, 69(4), 1268-1272 (2009).
37. Mahmood, U., and Weissleder, R., "Near-infrared optical imaging of proteases in cancer," Molecular Cancer Therapeutics, 2(5), 489-496 (2003).
38. McIntyre, J. O., and Matrisian, L. M., "Optical proteolytic beacons for in vivo detection of matrix metalloproteinase activity," Methods Mol Biol, 539, 1-20 (2009).