A longitudinal study to identify laboratory predictors of liver disease outcome in alagille syndrome

Journal of Pediatric Gastroenterology and Nutrition

Volumn 50, Issue 5, 2010, Pages 526-530

  Kamath, Binita M ^a   Munoz, Pedro S ^a   Bab, Natalie ^d   Baker, Alastair ^d   Chen, Zhongxue ^b   Spinner, Nancy B ^c   Piccoli, David A ^a  

^a HOSPITAL FOR SICK CHILDREN   (Canada)

^b Biostatistics and Data Management Core ^*  (Canada)

^c Division of Human Molecular Genetics   (Canada)

^d KING S COLLEGE HOSPITAL   (United Kingdom)

Author keywords

Alagille; Cholestasis; Liver; Transplantation

Indexed keywords

BILIRUBIN; BILIRUBIN GLUCURONIDE; CHOLESTEROL; JAGGED1;

ALAGILLE SYNDROME; ARTICLE; CHILD; CLINICAL ARTICLE; CONTROLLED STUDY; DISEASE SEVERITY; GENOTYPE PHENOTYPE CORRELATION; HUMAN; LABORATORY TEST; LIVER DISEASE; LONGITUDINAL STUDY; MUTATIONAL ANALYSIS; PREDICTION; PRIORITY JOURNAL; PROGNOSIS; RETROSPECTIVE STUDY;

ALAGILLE SYNDROME; BILIRUBIN; BIOLOGICAL MARKERS; CALCIUM-BINDING PROTEINS; CHILD; CHILD, PRESCHOOL; CHOLESTEROL; DISEASE PROGRESSION; GENOTYPE; HUMANS; INFANT; INTERCELLULAR SIGNALING PEPTIDES AND PROTEINS; LIVER DISEASES; LONGITUDINAL STUDIES; MEMBRANE PROTEINS; MUTATION; PHENOTYPE; PROGNOSIS; REFERENCE VALUES; RETROSPECTIVE STUDIES; SEVERITY OF ILLNESS INDEX;

EID: 77951804885     PISSN: 02772116     EISSN: None     Source Type: Journal    
DOI: 10.1097/MPG.0b013e3181cea48d     Document Type: Article

References (10)

1. Kamath BM, Bason L, Piccoli DA, et al. Consequences of JAG1 mutations. J Med Genet 2003;40:891-895
2. Alagille D, Estrada A, Hadchouel M, et al. Syndromic paucity of interlobular bile ducts (Alagille syndrome or arteriohepatic dysplasia): review of 80 cases. J Pediatr 1987;110:195-200.
3. Berard E, Sarles J, Triolo V, et al. Renovascular hypertension and vascular anomalies in Alagille syndrome. Pediatr Nephrol 1998; 12:121-124
4. Emerick KM, Krantz ID, Kamath BM, et al. Intracranial vascular abnormalities in patients with Alagille syndrome. J Pediatr Gastroenterol Nutr 2005;41:99-107.
5. Emerick KM, Rand EB, Goldmuntz E, et al. Features of Alagille syndrome in 92 patients: frequency and relation to prognosis. Hepatology 1999;29:822-829
6. Hyams JS, Berman MM, Davis BH. Tubulointerstitial nephropathy associated with arteriohepatic dysplasia. Gastroenterology 1983; 85:430-434
7. Kamath BM, Spinner NB, Emerick KM, et al. Vascular anomalies in Alagille syndrome: a significant cause of morbidity and mortality. Circulation 2004;109:1354-1358
8. Hoffenberg EJ, Narkewicz MR, Sondheimer JM, et al. Outcome of syndromic paucity of interlobular bile ducts (Alagille syndrome) with onset of cholestasis in infancy. J Pediatr 1995;127:220-224
9. Lykavieris P, Hadchouel M, Chardot C, et al. Outcome of liver disease in children with Alagille syndrome: a study of 163 patients. Gut 2001; 49:431-435
10. Quiros-Tejeira RE, Ament ME, Heyman MB, et al. Variable morbidity in alagille syndrome: a review of 43 cases. J Pediatr Gastroenterol Nutr 1999;29:431-437