Manganese accumulates within golgi apparatus in dopaminergic cells as revealed by synchrotron X-ray fluorescence nanoimaging

ACS Chemical Neuroscience

Volumn 1, Issue 3, 2010, Pages 194-203

  Carmona, Asunción ^a,b   Devès, Guillaume ^a,b   Roudeau, Stéphane ^a,b   Cloetens, Peter ^c   Bohic, Sylvain ^d,e   Ortega, Richard ^a,b  

^a UNIVERSITÉ DE BORDEAUX   (France)

^b CENTRE D ETUDES NUCLÉAIRES DE BORDEAUX GRADIGNAN   (France)

^c EUROPEAN SYNCHROTRON RADIATION FACILITY   (France)

^d INSERM   (France)

^e GRENOBLE INSTITUT DES NEUROSCIENCES   (France)

Author keywords

[No Author keywords available]

Indexed keywords

BREFELDIN A; MANGANESE;

ANIMAL CELL; ARTICLE; CONTROLLED STUDY; CYTOPLASM; DETOXIFICATION; DOPAMINERGIC NERVE CELL; GOLGI COMPLEX; NANOIMAGING; NEUROTOXICITY; NONHUMAN; RAT; X RAY FLUORESCENCE;

GOLGI APPARATUS; MANGANESE; PARKINSON'S DISEASE; PC12; PIXE; SYNCHROTRON;

ANIMALS; BREFELDIN A; CELL SURVIVAL; DOPAMINERGIC NEURONS; ENDOPLASMIC RETICULUM; GOLGI APPARATUS; GREEN FLUORESCENT PROTEINS; HOMEOSTASIS; IRON; MANGANESE; NEUROIMAGING; PC12 CELLS; PROTEIN SYNTHESIS INHIBITORS; RATS; SPECTROMETRY, X-RAY EMISSION; SYNCHROTRONS; TETRAZOLIUM SALTS; THIAZOLES; TRACE ELEMENTS;

EID: 77951753799     PISSN: None     EISSN: 19487193     Source Type: Journal    
DOI: 10.1021/cn900021z     Document Type: Article

References (46)

1. Couper, J. (1837) Sur les effets du peroxide de manganèse J. Chim. Méd., Pharm. Toxicol. 3, 233-235
2. Flynn, M.-R. and Susi, P. (2009) Neurological risks associated with manganese exposure from welding operations-A literature review Int. J. Hyg. Environ. Health 212, 459-469
3. Dickerson, R.-N. (2001) Manganese intoxication and parenteral nutrition Nutrition 17, 689-693
4. Stepens, A., Logina, I., Liguts, V., Aldins, P., Eksteina, I., Platkajis, A., Martinsone, I., Terauds, E., Rozentale, B. and Donaghy, M. (2008) A Parkinsonian syndrome in methcathinone users and the role of manganese N. Engl. J. Med. 358, 1009-1017
5. Gorell, J.-M., Johnson, C.-C., Rybicki, B.-A., Peterson, E.-L., Kortsha, G.-X., Brown, G.-G. and Richardson, R.-J. (1999) Occupational exposure to manganese, copper, lead, iron, mercury and zinc and the risk of Parkinson's disease Neurotoxicology 20, 239-247
6. Lucchini, R.-G., Albini, E., Benedetti, L., Borghesi, S., Coccaglio, R., Malara, E.-C., Parrinello, G., Garattini, S., Resola, S. and Alessio, L. (2007) High prevalence of Parkinsonian disorders associated to manganese exposure in the vicinities of ferroalloy industries Am. J. Ind. Med. 50, 788-800
7. Powers, K.-M., Smith-Weller, T., Franklin, G.-M., Longstreth, W.-T., Jr., Swanson, P.-D. and Checkoway, H. (2003) Parkinson's disease risks associated with dietary iron, manganese, and other nutrient intakes Neurology 60, 1761-1766
8. Aschner, M., Guilarte, T.-R., Schneider, J.-S. and Zheng, W. (2007) Manganese: Recent advances in understanding its transport and neurotoxicity Toxicol. Appl. Pharmacol. 221, 131-147
9. Vescovi, A., Facheris, L., Zaffaroni, A., Malanca, G. and Parati, E.-A. (1991) Dopamine metabolism alterations in a manganese-treated pheochromocytoma cell line (PC12) Toxicology 67, 129-142
10. Gunter, T.-E., Gavin, C.-E. and Gunter, K.-K. (2009) The case for manganese interaction with mitochondria Neurotoxicology 30, 727-729
11. Gavin, C.-E., Gunter, K.-K. and Gunter, T.-E. (1999) Manganese and calcium transport in mitochondria: Implications for manganese toxicity Neurotoxicology 20, 445-53
12. Morello, M., Canini, A., Mattioli, P., Sorge, R.-P., Alimonti, A., Bocca, B., Forte, G., Martorana, A., Bernardi, G. and Sancesario, G. (2008) Sub-cellular localization of manganese in the basal ganglia of normal and manganese-treated rats. An electron spectroscopy imaging and electron energy-loss spectroscopy study Neurotoxicology 29, 60-72
13. Kalia, K., Jiang, W. and Zheng, W. (2008) Manganese accumulates primarily in nuclei of cultured brain cells Neurotoxicology 29, 466-470
14. Roth, J.-A. and Garrick, M.-D. (2003) Iron interactions and other biological reactions mediating the physiological and toxic actions of manganese Biochem. Pharmacol. 66, 1-13
15. Zheng, W. and Zhao, Q. (2001) Iron overload following manganese exposure in cultured neuronal, but not neuroglial cells Brain Res. 897, 175-179
16. Kwik-Uribe, C. and Smith, D.-R. (2006) Temporal responses in the disruption of iron regulation by manganese J Neurosci. Res. 83, 1601-1610
17. Ortega, R., Devès, G. and Carmona, A. (2009) Bio-metals imaging and speciation in cells using proton and synchrotron radiation X-ray micro-spectroscopy J. R. Soc. Interface 6, S649-S658
18. Roth, J.-A., Feng, L., Walowitz, J. and Browne, R.-W. (2000) Manganese-induce rat pheochromocytoma (PC12) cell death is independent of caspase activation J. Neurosci. Res. 61, 162-171
19. Deng, Y., Luan, Y., Qing, H., Xie, H., Lu, J. and Zhou, J. (2008) The formation of catechol isoquinolines in PC12 cells exposed to manganese Neurosci. Lett. 444, 122-126
20. Pezzati, R., Bossi, M., Podini, P., Meldolesi, J. and Grohovaz, F. (1997) High-resolution calcium mapping of the endoplasmic reticulum-Golgi-exocytic membrane system. Electron energy loss imaging analysis of quick frozen-freeze dried PC12 cells Mol. Biol. Cell 8, 1501-1512
21. Fukuda, M. and Mikoshiba, K. (1999) A novel alternatively spliced variant of synaptotagmin VI lacking a transmembrane domain J. Biol. Chem. 274, 31428-31434
22. Masuda, S., Murakami, M., Takanezawa, Y., Aoki, J., Arai, H., Ishikawa, Y., Ishii, T., Arioka, M. and Kudo, I. (2005) Neuronal expression and neuritogenic action of group X secreted phospholipase A2 J. Biol. Chem. 280, 23203-22214
23. Pelham, H.,R.,B. (1991) Multiple targets for brefeldin A Cell 67, 449-451
24. Gavin, C.-E., Gunter, K.-K. and Gunter, T.-E. (1990) Manganese and calcium efflux kinetics in brain mitochondria. Relevance to manganese toxicity Biochem. J. 266, 329-34
25. Burton, N.-C. and Guilarte, T.-R. (2009) Manganese neurotoxicity: Lessons learned from longitudinal studies in nonhuman primates Environ. Health Perspect. 117, 325-332
26. Ortega, R., Moretto, P., Fajac, A., Benard, J., Llabador, Y. and Simonoff, M. (1996) Quantitative mapping of platinum and essential trace metal in cisplatin resistant and sensitive human ovarian adenocarcinoma cells Cell. Mol. Biol. 42, 77-88
27. Culotta, V.-C., Yang, M. and Hall, M.-D. (2005) Manganese transport and trafficking: lessons learned from Saccharomyces cerevisiae Eukaryotic Cell 4, 1159-1165
28. Peiter, E., Montanini, B., Gobert, A., Pedas, P., Husted, S., Maathuis, F.J-., Blaudez, D., Chalot, M. and Sanders, D. (2007) A secretory pathway-localized cation diffusion facilitator confers plant manganese tolerance Proc. Natl. Acad. Sci. U.S.A. 104, 8532-8537
29. Larsen, A.-K., Escargueil, A.-E. and Skladanowski, A. (2000) Resistance mechanisms associated with altered intracellular distribution of anticancer agents Pharmacol. Ther. 85, 217-229
30. Chun, H.-S., Lee, H. and Son, J.-H. (2001) Manganese induces endoplasmic reticulum (ER) stress and activates multiple caspases in nigral dopaminergic neuronal cells, SN4741 Neurosci. Lett. 316, 5-8
31. Tjalkens, R.-B., Zoran, M.-J., Mohl, B. and Barhoumi, R. (2006) Manganese suppresses ATP-dependent intercellular calcium waves in astrocyte networks through alteration of mitochondrial and endoplasmic reticulum calcium dynamics Brain Res. 113, 210-219
32. Towler, M.-C., Prescott, A.-R., James, J., Lucocq, J.-M. and Ponnambalam, S. (2000) The manganese cation disrupts membrane dynamics along the secretory pathway Exp. Cell Res. 259, 167-179
33. Higashi, Y., Asanuma, M., Miyazaki, I., Hattori, N., Mizuno, Y. and Ogawa, N. (2004) Parkin attenuates manganese-induced dopaminergic cell death J. Neurochem. 89, 1490-1497
34. Gitler, A.-D., Chesi, A., Geddie, M.-L., Strathearn, K.-E., Hamamichi, S., Hill, K.-J., Caldwell, K.-A., Caldwell, G.-A., Cooper, A.-A., Rochet, J.-C. and Lindquist, S. (2009) Alpha-synuclein is part of a diverse and highly conserved interaction network that includes PARK9 and manganese toxicity Nat. Genet. 41, 308-315
35. Fan, J., Hu, Z., Zeng, L., Lu, W., Tang, X., Zhang, J. and Li, T. (2008) Golgi apparatus and neurodegenerative diseases Int. J. Dev. Neurosci. 26, 523-34
36. Kwik-Uribe, C.-L., Reaney, S., Zhu, Z. and Smith, D. (2003) Alterations in cellular IRP-dependent iron regulation by in vitro manganese exposure in undifferentiated PC12 cells Brain Res. 973, 1-15
37. Roth, J.-A., Horbinski, C., Feng, L., Dolan, K.-G., Higgins, D. and Garrick, M.-D. (2000) Differential localization of divalent metal transporter 1 with and without iron response element in rat PC12 and sympathetic neuronal cells J. Neurosci. 20, 7595-7601
38. Zheng, W., Zhao, Q., Slavkovich, V., Aschner, M. and Graziano, J.-H. (1999) Alteration of iron homeostasis following chronic exposure to manganese in rats Brain Res. 833, 125-132
39. Garcia, S.-J., Gellein, K., Syversen, T. and Aschner, M. (2006) A manganese-enhanced diet alters brain metals and transporters in the developing rat Toxicol. Sci. 92, 516-25
40. Greene, L.-A. and Tischler, A.-S. (1976) Establishment of a noradrenergic clonal line of rat adrenal pheochromocytoma cells which respond to nerve growth factor Proc. Natl. Acad. Sci. U.S.A. 73, 2424-2428
41. Carmona, A., Devès, G. and Ortega, R. (2008) Quantitative micro-analysis of metal ions in subcellular compartments of cultured dopaminergic cells by combination of three ion beam techniques Anal. Bioanal. Chem. 390, 1585-1594
42. Greaves, J., Salaun, Ch., Fukata, Y., Fukata, M. and Chamberlain, L.-H. (2008) Palmitoylation and membrane interactions of the neuroprotective chaperone cysteine-string protein J. Biol. Chem. 283, 25014-25026
43. Hignette, O., Cloetens, P., Rostaing, G., Bernard, P. and Morawe, C. (2005) Efficient sub 100 nm focusing of hard x rays Rev. Sci. Instrum. 76 063709
44. Solé, V.-A., Papillon, E., Cotte, M., Walter, Ph. and Susini, J. (2007) A multiplatform code for the analysis of energy-dispersive X-ray fluorescence spectra Spectrochim. Acta B 62, 63-68
45. Campbell, J.-L., Hopman, T.-L., Maxwell, J.-A. and Nejedly, Z. (2000) The guelph PIXE software package III: Alternative proton database Nucl. Instrum. Methods B 170, 193-204
46. Mayer, M. (1997) SIMNRA Users Guide; Max-Planck-Institut für Plasmaphysik: Garching, Germany.