Association of two single-isomer anionic CD in NACE for the chiral and achiral separation of fenbendazole, its sulphoxide and sulphone metabolites: Application to their determination after in vitro metabolism

Electrophoresis

Volumn 31, Issue 9, 2010, Pages 1482-1487

  Rousseau, Anne ^a   Gillotin, Florian ^b   Chiap, Patrice ^b   Crommen, Jacques ^a   Fillet, Marianne ^a   Servais, Anne Catherine ^a  

^a UNIVERSITY OF LIÈGE   (Belgium)

^b Advanced Technology Corporation   (Belgium)

Author keywords

Benzimidazole compounds; In vitro metabolites; Nonaqueous capillary electrophoresis; Single isomer anionic cyclodextrins

Indexed keywords

BIOMOLECULES; CAPILLARY ELECTROPHORESIS; ENANTIOMERS; METABOLISM; PHYSIOLOGY;

BENZIMIDAZOLE COMPOUND; BENZIMIDAZOLES; FENBENDAZOLE; IN VITRO METABOLITE; IN-VITRO; NON-AQUEOUS CAPILLARY ELECTROPHORESIS; SINGLE-ISOMER; SINGLE-ISOMER ANIONIC CYCLODEXTRIN; SULPHOXIDE; Β-CD;

METABOLITES;

ALBENDAZOLE; BENZIMIDAZOLE; CYCLODEXTRIN; FENBENDAZOLE; MEBENDAZOLE; OXFENDAZOLE; PHENOBARBITAL; SULFONE; SULFOXIDE; TIABENDAZOLE;

ANIMAL TISSUE; ARTICLE; CAPILLARY ELECTROPHORESIS; CHIRALITY; DRUG METABOLISM; DRUG STRUCTURE; ENANTIOMER; IN VITRO STUDY; ISOMER; LIVER MICROSOME; MALE; NONAQUEOUS CAPILLARY ELECTROPHORESIS; NONHUMAN; RAT; SEPARATION TECHNIQUE;

EID: 77951746913     PISSN: 01730835     EISSN: 15222683     Source Type: Journal    
DOI: 10.1002/elps.200900723     Document Type: Article

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