Comparison of the clinical significance of the papanicolaou test interpretations LSIL cannot rule out HSIL and ASC-H

Diagnostic Cytopathology

Volumn 38, Issue 5, 2010, Pages 313-317

  Difurio, Megan J ^a   Mailhiot, Thomas ^a   Sundborg, Michael J ^a   Nauschuetz, Karen K ^a  

^a BROOKE ARMY MEDICAL CENTER   (United States)

Author keywords

ASC H; ASCCP guidelines; LSIL cannot rule out HSIL; The Bethesda system; ThinPrep

Indexed keywords

ALGORITHM; ARTICLE; COLPOSCOPY; COMPARATIVE STUDY; CONTROLLED STUDY; FEMALE; FOLLOW UP; HIGH GRADE SQUAMOUS INTRAEPITHELIAL LESION; HUMAN; HUMAN TISSUE; INCIDENCE; LOW GRADE SQUAMOUS INTRAEPITHELIAL LESION; MAJOR CLINICAL STUDY; PAPANICOLAOU TEST; PRACTICE GUIDELINE; PRIORITY JOURNAL; STATISTICAL SIGNIFICANCE; UTERINE CERVIX BIOPSY; UTERINE CERVIX CARCINOMA IN SITU; UTERINE CERVIX CYTOLOGY; WART VIRUS;

ADOLESCENT; ADULT; AGED; CERVICAL INTRAEPITHELIAL NEOPLASIA; DIAGNOSIS, DIFFERENTIAL; FEMALE; FOLLOW-UP STUDIES; HUMANS; MIDDLE AGED; NEOPLASMS, SQUAMOUS CELL; UTERINE CERVICAL NEOPLASMS; VAGINAL SMEARS; YOUNG ADULT;

EID: 77951735906     PISSN: 87551039     EISSN: 10970339     Source Type: Journal    
DOI: 10.1002/dc.21194     Document Type: Article

References (28)

1. Solomon D, Nayar R. The Bethesda System for reporting cervical cytology: Definitions, criteria, and explanatory notes,2nd ed. New York: Springer-Verlag; 2004. p 107-108.
2. Sherman ME, Solomon D, Schiffman M. Qualification of ASCUS. A comparison of equivocal LSIL and equivocal HSIL cervical cytology in the ASCUS LSIL Triage Study. Am J Clin Pathol 2001; 116:386-394. (Pubitemid 32851972)
3. Sherman ME, Tabbara SO, Scott DR, et al." ASCUS, Rule Out HSIL": Cytologic features, histologic correlates, and human papillomavirus detection. Mod Pathol 1999;12:335-343.
4. Alli PM, Ali SZ. Atypical squamous cells of undetermined significance-Rule out high-grade squamous intraepithelial lesion: Cytopathologic characteristics and clinical correlates. Diagn Cytopathol 2003;28:308-312.
5. Louro AP, Roberson J, Eltoum I, Chhieng DC. Atypical squamous cells, cannot exclude high-grade squamous intraepithelial lesion: A follow-up study of conventional and liquid-based preparations in a high-risk population. Am J Clin Pathol 2003;120:392-397. (Pubitemid 37295110)
6. Selvaggi SM. Reporting of atypical squamous cells, cannot exclude high-grade squamous intraepithelial lesion (ASC-H) on cervical samples: Is it significant? Diagn Cytopathol 2003;29:38-41.
7. Mokhtar GA, Roustan Delatour NLD, Assiri AH, Gilliatt MA, Senterman M, Islam S. Atypical squamous cells, cannot exclude high-grade squamous intraepithelial lesion, cytohistologic correlation study with diagnostic pitfalls. Acta Cytol 2008;52:169-177. (Pubitemid 351441127)
8. Power P, Gregoire J, Duggan M, Nation J. Low-grade Pap smears containing occasional high-grade cells as a predictor of high-grade dysplasia. J Obstet Gynaecol Canada 2006;28:884-887.
9. Howard MT, Cohen DW, Underwood DL, Deeds DA, Booth CN. Utilization of ASC-H, LSIL, cannot exclude HSIL (LSIL-H) and HSIL terminology following implementation of the ThinPrep imaging system. Mod Pathol 2007;20(Suppl 2):71A.
10. Elsheikh TM, Kirkpatrick JL, Wu HH. The significance of "low-grade squamous intraepithelial lesion, cannot exclude high-grade squamous intraepithelial lesion" as a distinct squamous abnormality category in Papanicolaou tests. Cancer Cytopathol 2006;108:277-281.
11. Owens CL, Moats DR, Burroughs FH, Gustafson KS. "Low-grade squamous intraepithelial lesion, cannot exclude high-grade squamous intraepithelial lesion" is a distinct cytologic category, histologic outcomes and HPV prevalence. Am J Clin Pathol 2007;128: 398-403.
12. Shidham VB, Kumar N, Narayan R, Brotzman GL. Should LSIL with ASC-H (LSIL-H) in cervical smears be an independent category? A study on SurePath™ specimens with review of the literature. CytoJournal 2007;4:7.
13. Alsharif M, Kjeldahl K, Curran C, Miller S, Gulbahce HE, Pambuccian SE. Clinical significance of the diagnosis of low-grade human squamous intraepithelial lesion, cannot exclude a high grade lesion. Cancer Cytopathol 2009;117:92-100.
14. Underwood D, Prok A, Booth C, Brainard J, Chen L. Clinical outcomes of patients with a cytologic interpretation of "LSIL, cannot exclude HSIL (LSIL-H)" in Pap tests: A Retrospective Follow-up Study. Cancer Cytopathol 2006;108(Suppl 5):378.
15. Wang Y, Patel K, Sugrue C, Wasserman P. Low-grade squamous intraepithelial lesion cannot exclude high-grade squamous intraepithelial lesion (LGSIL-H): Do we need another category in Bethesda System? Cancer Cytopathol 2006;108(Suppl 5):370.
16. Hong SR, Kim BM, Park JS, Choi KJ, Kim HS. Evaluation of low-grade squamous intraepithelial lesion, cannot exclude high-grade squamous intraepithelial lesion on cervical smear. Cancer Cytopathol 2007;108(Suppl 5):387.
17. Jones BA, Novis DA. Cervical biopsy-cytology correlation. A College of American Pathologists Q-Probes Study of 22,439 correlations in 348 laboratories. Arch Pathol Lab Med 1996;120:523-531.
18. Kir G, Cetiner H, Gurbuz A, Karateke A. Reporting of "LSIL with ASC-H" on cervicovaginal smears: Is it a valid category to predict cases with HSIL follow-up? Eur J Gynecol Oncol 2004;25:462-464.
19. Nasser SM, Cibas ES, Crum CP, Faquin WC. The significance of the Papanicolaou smear diagnosis of low-grade squamous intraepithelial lesion cannot exclude high-grade squamous intraepithelial lesion. Cancer Cytopathol 2003;99:272-276. (Pubitemid 37248374)
20. Walsh BG, Michaels S, Steele C, Khurana KK. Clinical significance of the Pap smear diagnosis of LSIL cannot exclude HSIL: Comparison with a patient population with Pap smear findings of LSIL [abstract]. Acta Cytol 2000;44:857.
21. Baker JJ, Fontana JL. "LSIL-H" Cervicovaginal cytology specimens: Biopsy follow-up and clinical significance [abstract]. Acta Cytol 2004;48:668.
22. Saad RS, Mahdavy M, Takei H, Ruiz B. Clinical significance of cytologic diagnosis of low-grade squamous intraepithelial lesion with few cells suggestive of high grade: A cytohistologic correlation study [abstract]. Acta Cytol 2004;48:659.
23. Booth CN, Massarani-Wafai R, Salhadar A, Weirick J, Wojcik EM. Is LSIL, cannot exclude HSIL (LGHSIL) a valid Pap test interpretation? Mod Pathol 2005;18 (Suppl 1):61A.
24. Mcgrath CM, Kurtis JD, Yu GH. Evaluation of mild-to-moderate dysplasia on cervical-endocervical (Pap) smear: A subgroup of patients who bridge LSIL and HSIL. Diagn Cytopathol 2000;23: 245-248.
25. O'Brien D, Brainard J, Chen L, Prok A, Booth C. Impact of the ThinPrep imaging system on the frequency of LSIL, cannot exclude HSIL: Correlation of HPV and follow-up data. Cancer Cytopathol 2006;108 (Suppl 5):383-384.
26. Wright TC, Massad S, Dunton CJ, Spitzer M, Wilkinson EJ, Solomon D. 2006 Consensus guidelines for the management of women with abnormal cervical cancer screening test. Am J Obstet Gynecol 2007; 197:346-355. (Pubitemid 47464164)
27. Saab BA, Austin RM. Management of squamous intraepithelial lesions of indeterminate grade (Letter to the Editor and Reply). Am J Obstet Gynecol 2008;199:e13-14 (Reply e14).
28. Bandyopadhyay S, Austin RM, Dabbs D, Zhao C. Adjunctive human papillomavirus DNA testing is a useful option in some clinical settings for disease risk assessment and triage of females with ASC-H Papanicolaou test results. Arch Pathol Lab Med 2008;132: 1874-1881.