A functional epidermal growth factor (EGF) polymorphism, EGF serum levels and renal cell carcinoma risk in a Chinese population

Journal of Human Genetics

Volumn 55, Issue 4, 2010, Pages 236-240

  Zhu, Jian ^a   Meng, Xiaoxin ^a   Yan, Fu ^a   Qin, Chao ^a   Wang, Meilin ^a   Ding, Qi ^a   Li, Pu ^a   Yang, Jian ^a   Ju, Xiaobing ^a   Zhang, Zhengdong ^a   Wang, Shui ^a   Yin, Changjun ^a  

^a NANJING MEDICAL UNIVERSITY   (China)

Author keywords

EGF polymorphism; EGF serum levels; Genetic susceptibility; RCC

Indexed keywords

EPIDERMAL GROWTH FACTOR;

ADULT; ARTICLE; CANCER RISK; CANCER SUSCEPTIBILITY; CHINESE; CONTROLLED STUDY; DNA POLYMORPHISM; FEMALE; GENE FREQUENCY; GENETIC RISK; GENETIC SUSCEPTIBILITY; GENOTYPE; HETEROZYGOTE; HUMAN; KIDNEY CARCINOMA; MAJOR CLINICAL STUDY; MALE; PROTEIN BLOOD LEVEL; RISK ASSESSMENT; SINGLE NUCLEOTIDE POLYMORPHISM;

ADULT; AGED; ASIAN CONTINENTAL ANCESTRY GROUP; BODY MASS INDEX; CARCINOMA, RENAL CELL; CASE-CONTROL STUDIES; CHINA; EPIDERMAL GROWTH FACTOR; FEMALE; GENE FREQUENCY; GENETIC PREDISPOSITION TO DISEASE; GENOTYPE; HUMANS; KIDNEY NEOPLASMS; LOGISTIC MODELS; MALE; MIDDLE AGED; POLYMORPHISM, SINGLE NUCLEOTIDE; RISK FACTORS; SMOKING;

EID: 77951730344     PISSN: 14345161     EISSN: None     Source Type: Journal    
DOI: 10.1038/jhg.2010.12     Document Type: Article

References (27)

1. Jemal, A., Siegel, R., Ward, E., Hao, Y., Xu, J. & Thun, M. J. Cancer statistics, 2009. CA Cancer J. Clin. 59, 225-249 (2009).
2. Yang, L., Parkin, D. M., Ferlay, J., Li, L. & Chen, Y. Estimates of cancer incidence in China for 2000 and projections for 2005. Cancer Epidemiol. Biomarkers Prev. 14, 243-250 (2005).
3. Lipworth, L., Tarone, R. E. & McLaughlin, J. K. The epidemiology of renal cell carcinoma. J. Urol. 176, 2353-2358 (2006).
4. Setiawan, V. W., Stram, D. O., Nomura, A. M., Kolonel, L. N. & Henderson, B. E. Risk factors for renal cell cancer: the multiethnic cohort. Am. J. Epidemiol. 166, 932-940 (2007).
5. Hunt, J. D., van der Hel, O. L., McMillan, G. P., Boffetta, P. & Brennan, P. Renal cell carcinoma in relation to cigarette smoking: meta-analysis of 24 studies. Int. J. Cancer 114, 101-108 (2005).
6. Normanno, N., De Luca, A., Bianco, C., Strizzi, L., Mancino, M., Maiello, M. R. et al. Epidermal growth factor receptor (EGFR) signaling in cancer. Gene 366, 2-16 (2006).
7. Laurence, D. J. & Gusterson, B. A. The epidermal growth factor. A review of structural and functional relationships in the normal organism and in cancer cells. Tumour Biol. 11, 229-261 (1990).
8. Carpenter, G. & Cohen, S. Epidermal growth factor. J. Biol. Chem. 265, 7709-7712 (1990).
9. Shahbazi, M., Pravica, V., Nasreen, N., Fakhoury, H., Fryer, A. A., Strange, R. C. et al. Association between functional polymorphism in EGF gene and malignant melanoma. Lancet 359, 397-401 (2002).
10. Amend, K. L., Elder, J. T., Tomsho, L. P., Bonner, J. D., Johnson, T. M., Schwartz, J. et al. EGF gene polymorphism and the risk of incident primary melanoma. Cancer Res. 64, 2668-2672 (2004).
11. McCarron, S. L., Bateman, A. C., Theaker, J. M. & Howell, W. M. EGF +61 gene polymorphism and susceptibility to and prognostic markers in cutaneous malignant melanoma. Int. J. Cancer 107, 673-675 (2003).
12. Goto, Y., Ando, T., Goto, H. & Hamajima, N. No association between EGF gene polymorphism and gastric cancer. Cancer Epidemiol. Biomarkers Prev. 14, 2454-2456 (2005).
13. Hamai, Y., Matsumura, S., Matsusaki, K., Kitadai, Y., Yoshida, K., Yamaguchi, Y. et al. A single nucleotide polymorphism in the 5¢ untranslated region of the EGF gene is associated with occurrence and malignant progression of gastric cancer. Pathobiology 72, 133-138 (2005).
14. Wang, Y., Tian, T., Hu, Z., Tang, J., Wang, S., Wang, X. et al. EGF promoter SNPs, plasma EGF levels and risk of breast cancer in Chinese women. Breast Cancer Res. Treat. 111, 321-327 (2008).
15. Lanuti, M., Liu, G., Goodwin, J. M., Zhai, R., Fuchs, B. C., Asomaning, K. et al. A functional epidermal growth factor (EGF) polymorphism, EGF serum levels, and esophageal adenocarcinoma risk and outcome. Clin. Cancer Res. 14, 3216-3222 (2008).
16. Olayioye, M. A., Neve, R. M., Lane, H. A. & Hynes, N. E. The ErbB signaling network: receptor heterodimerization in development and cancer. EMBO J. 19, 3159-3167 (2000).
17. Normanno, N., Bianco, C., Strizzi, L., Mancino, M., Maiello, M. R., De Luca, A. et al. The ErbB receptors and their ligands in cancer: an overview. Curr. Drug Targets 6, 243-257 (2005).
18. Tomaszewski, J., Miturski, R. & Kotarski, J. [Concentration of epidermal growth factor (EGF) in serum of women with endometrial cancer]. Ginekol. Pol. 67, 248-253 (1996).
19. Wells, A. EGF receptor. Int. J. Biochem. Cell Biol. 31, 637-643 (1999).
20. Singh, A. B. & Harris, R. C. Autocrine, paracrine and juxtacrine signaling by EGFR ligands. Cell Signal 17, 1183-1193 (2005).
21. Salazar, G. & Gonzalez, A. Novel mechanism for regulation of epidermal growth factor receptor endocytosis revealed by protein kinase A inhibition. Mol. Biol. Cell 13, 1677-1693 (2002).
22. Friedman, L. M., Rinon, A., Schechter, B., Lyass, L., Lavi, S., Bacus, S. S. et al. Synergistic down-regulation of receptor tyrosine kinases by combinations of mAbs: implications for cancer immunotherapy. Proc. Natl Acad. Sci. USA 102, 1915-1920 (2005).
23. Zhao, X., Dai, W., Zhu, H., Zhang, Y., Cao, L., Ye, Q. et al. Epidermal growth factor (EGF) induces apoptosis in a transfected cell line expressing EGF receptor on its membrane. Cell Biol. Int. 30, 653-658 (2006).
24. Jin, G., Miao, R., Deng, Y., Hu, Z., Zhou, Y., Tan, Y. et al. Variant genotypes and haplotypes of the epidermal growth factor gene promoter are associated with a decreased risk of gastric cancer in a high-risk Chinese population. Cancer Sci. 98, 864-868 (2007).
25. Kang, S., Kim, J. W., Park, N. H., Song, Y. S., Park, S. Y. Kang, S. B. et al. Epidermal growth factor 61 A/G polymorphism and uterine cervical cancer. Int. J. Gynecol. Cancer 17, 492-496 (2007).
26. Randerson-Moor, J. A., Gaut, R., Turner, F., Whitaker, L., Barrett, J. H., Silva Idos, S. et al. The relationship between the epidermal growth factor (EGF) 5¢UTR variant A61G and melanoma/nevus susceptibility. J. Invest. Dermatol. 123, 755-759 (2004).
27. James, M. R., Hayward, N. K., Dumenil, T., Montgomery, G. W., Martin, N. G. & Duffy, D. L. Epidermal growth factor gene (EGF) polymorphism and risk of melanocytic neoplasia. J. Invest. Dermatol. 123, 760-762 (2004).