Parameters of the thrombogram are associated with serum 25-hydroxyvitamin D levels at baseline, but not affected during supplementation with vitamin D

Thrombosis Research

Volumn 125, Issue 5, 2010, Pages

  Jorde, Rolf ^a,b   Sneve, Monica ^a   Torjesen, Peter ^c   Figenschau, Yngve ^b   Hansen, John Bjarne ^a  

^a UNIVERSITY OF TROMSØ   (Norway)

^b UNIVERSITY HOSPITAL OF NORTH NORWAY   (Norway)

^c AKER UNIVERSITY HOSPITAL   (Norway)

Author keywords

Obesity; plasminogen activator inhibitor; thrombogram; tissue plasminogen activator antigen; vitamin D

Indexed keywords

25 HYDROXYVITAMIN D; CALCIUM; COLECALCIFEROL; DECRISTOL; NYCOPLUS CALCIUM; PLACEBO; PLASMINOGEN ACTIVATOR INHIBITOR 1; THROMBOPLASTIN; TISSUE PLASMINOGEN ACTIVATOR; UNCLASSIFIED DRUG;

ADULT; AGED; ARTICLE; BODY MASS; CALIBRATED AUTOMATED THROMBOGRAM; CLINICAL TRIAL; CONTROLLED CLINICAL TRIAL; CONTROLLED STUDY; DEVICE; DIET; DRUG MEGADOSE; FEMALE; HEIGHT; HEMOSTASIS; HUMAN; MAJOR CLINICAL STUDY; MALE; OBESITY; PHYSICAL ACTIVITY; PHYSICAL PARAMETERS; PRIORITY JOURNAL; RANDOMIZED CONTROLLED TRIAL; THROMBIN TIME; VITAMIN BLOOD LEVEL; VITAMIN SUPPLEMENTATION; WEIGHT; WEIGHT CHANGE;

DIETARY SUPPLEMENTS; FEMALE; HUMANS; MALE; MIDDLE AGED; NORWAY; OBESITY; THROMBOSIS; TREATMENT OUTCOME; ULTRAVIOLET THERAPY; VITAMIN D;

EID: 77951667276     PISSN: 00493848     EISSN: None     Source Type: Journal    
DOI: 10.1016/j.thromres.2009.12.011     Document Type: Article

References (24)

1. DeLuca H.F. Overview of general physiologic features and functions of vitamin D. Am J Clin Nutr 80 (2004) 1689S-1696S
2. Jones G., Strugnell S.A., and DeLuca H.F. Current understanding of the molecular actions of vitamin D. Physiol Rev 78 (1998) 1193-1231
3. Scragg R., Sowers M., and Bell C. Serum 25-hydroxyvitamin D, ethnicity, and blood pressure in the Third National Health and Nutrition Examination Survey. Am J Hypertens 20 (2007) 713-719
4. Mattila C., Knekt P., Männistö S., Rissanen H., Laaksonen M.A., Montonen J., et al. Serum 25-hydroxyvitamin D concentration and subsequent risk of type 2 diabetes. Diabetes Care 30 (2007) 2569-2570
5. Giovannucci E., Liu Y., Hollis B.W., and Rimm E.B. 25-hydroxyvitamin D and risk of myocardial infarction in men: a prospective study. Arch Intern Med 168 (2008) 1174-1180
6. Melamed M.L., Michos E.D., Post W., and Astor B. 25-hydroxyvitamin D levels and the risk of mortality in the general population. Arch Intern Med 168 (2008) 1629-1637
7. Lindqvist P.G., Epstein E., and Olsson H. Does an active sun exposure habit lower the risk of venous thrombotic events? A D-lightful hypothesis. J Thromb Haemost 7 (2009) 605-610
8. Scragg R. Seasonality of cardiovascular disease mortality and the possible protective effect of ultra-violet radiation. Int J Epidemiol 10 (1981) 337-341
9. Koyama T., Shibakura M., Ohsawa M., Kamiyama R., and Hirosawa S. Anticoagulant effects of 1alpha, 25-dihydroxyvitamin D3 on human myelogenous leukemia cells and monocytes. Blood 92 (1998) 160-167
10. Aihara K., Azuma H., Akaike M., Ikeda Y., Yamashita M., Sudo T., et al. Disruption of nuclear vitamin D receptor gene causes enhanced thrombogenicity in mice. J Biol Chem 279 (2004) 35798-35802
11. Jorde R., Haug E., Figenschau Y., and Hansen J.B. Serum levels of vitamin D and haemostatic factors in healthy subjects: the Tromsø study. Acta Haematol 117 (2007) 91-97
12. Wu-Wong J.R., Nakane M., and Ma J. Vitamin D analogs modulate the expression of plasminogen activator inhibitor-1, thrombospondin-1 and thrombomodulin in human aortic smooth muscle cells. J Vasc Res 44 (2007) 11-18
13. Puri S., Bansal D.D., Uskoković M.R., and MacGregor R.R. Induction of tissue plasminogen activator secretion from rat heart microvascular cells by fM 1, 25(OH)(2)D(3). Am J Physiol Endocrinol Metab 278 (2000) E293-E301
14. Sneve M., Figenschau Y., and Jorde R. Supplementation with cholecalciferol does not result in weight reduction in overweight and obese subjects. Eur J Endocrinol 159 (2008) 675-684
15. Hemker H.C., Giesen P., AlDieri R., Regnault V., de Smed E., Wagenvoord R., et al. Calibrated automated thrombin generation measurement in clotting plasma. Pathophysiol Haemost Thromb 33 (2003) 4-15
16. Osmancevic A., Nilsen L.T., Landin-Wilhelmsen K., Søyland E., Abusdal Torjesen P., Hagve T.A., et al. Effect of climate therapy at Gran Canaria on vitamin D production, blood glucose and lipids in patients with psoriasis. J Eur Acad Dermatol Venereol 23 (2009) 1133-1140
17. Agledahl I., Brodin E., Svartberg J., and Hansen J.B. Plasma free tissue factor pathway inhibitor (TFPI) levels and TF-induced thrombin generation ex vivo in men with low testosterone levels. Thromb Haemost 101 (2009) 471-477
18. Agledahl I, Brodin E, Svartberg J, Hansen JB. Impact of long-term testosterone treatment on plasma free TFPI levels and TF-induced thrombin generation ex vivo in elderly men with low testosterone levels. Thromb Haemost 2009;102:945-50.
19. Mannhalter C., and Quehenberger P. Laboratory methods in the haemostatic laboratory. Thromb Haemost 96 (2006) 545-546
20. van Hylckama Vlieg A., Christiansen S.C., Luddington R., Cannegieter S.C., Rosendaal F.R., and Baglin T.P. Elevated endogenous thrombin potential is associated with an increased risk of a first deep venous thrombosis but not with the risk of recurrence. Br J Haematol 138 (2007) 769-774
21. Tripodi A., Legnani C., Chantarangkul V., Cosmi B., Palareti G., and Mannucci P.M. High thrombin generation measured in the presence of thrombomodulin is associated with an increased risk of recurrent venous thromboembolism. J Thromb Haemost 6 (2008) 1327-1333
22. Hron G., Kollars M., Binder B.R., Eichinger S., and Kyrle P.A. Identification of patients at low risk for recurrent venous thromboembolism by measuring thrombin generation. JAMA 296 (2006) 397-402
23. Bischoff-Ferrari H.A., Giovannucci E., Willett W.C., Dietrich T., and Dawson-Hughes B. Estimation of optimal serum concentrations of 25-hydroxyvitamin D for multiple health outcomes. Am J Clin Nutr 84 (2006) 18-28
24. Spronk H.M., Govers-Riemslag J.W., and ten Cate H. The blood coagulation system as a molecular machine. Bioessays 25 (2003) 1220-1228