Hydrocortisone supplementation enhances hemodynamic stability in brain-dead patients

Anesthesiology

Volumn 112, Issue 5, 2010, Pages 1204-1210

  Nicolas Robin, Armelle ^a   Barouk, Jérome D ^a   Amour, Julien ^a   Coriat, Pierre ^a   Riou, Bruno ^a   Langeron, Olivier ^a  

^a PITIÉ SALPÊTRIÈRE HOSPITAL   (France)

Author keywords

[No Author keywords available]

Indexed keywords

HYDROCORTISONE; HYPERTENSIVE AGENT; NORADRENALIN; TETRACOSACTIDE;

ADRENAL INSUFFICIENCY; ADULT; ARTICLE; BRAIN DEATH; CLINICAL ARTICLE; CLINICAL OBSERVATION; CONTROLLED STUDY; DRUG DOSE REDUCTION; FEMALE; HEMODYNAMICS; HUMAN; HYDROCORTISONE BLOOD LEVEL; HYPOTENSION; INTERVENTION STUDY; MALE; MEAN ARTERIAL PRESSURE; OUTCOME ASSESSMENT; PRIORITY JOURNAL; PROVOCATION TEST; SINGLE DRUG DOSE; SUPPLEMENTATION;

EID: 77951666892     PISSN: 00033022     EISSN: 15281175     Source Type: Journal    
DOI: 10.1097/ALN.0b013e3181d4f34d     Document Type: Article

References (36)

1. Garrity ER, Moore J, Mulligan MS, Shearon TH, Zucker MJ, Murray S: Heart and lung transplantation in the United States, 1996-2005. Am J Transplant 2007; 7:1390-1403
2. Salim A, Martin M, Brown C, Rhee P, Demetriades D, Belzberg H: The effect of a protocol of aggressive donor management: Implications for the national organ donor shortage. J Trauma 2006; 61:429-433
3. Giral M, Bertola JP, Foucher Y, Villers D, Bironneau E, Blanloeil Y, Karam G, Daguin P, Lerat L, Soulillou JP: Effect of brain-dead donor resuscitation on delayed graft function: Results of a monocentric analysis. Transplantation 2007; 83:1174-1181
4. Schnuelle P, Berger S, de Boer J, Persijn G, van der Woude FJ: Donor employment of vasopressors and its impact on allograft survival after transplantation. Transplant Proc 2001; 33:1282-1283
5. Marik PE, Pastores SM, Annane D, Meduri GU, Sprung CL, Arlt W, Keh D, Briegel J, Beishuizen A, Dimopoulou I, Tsagarakis S, Singer M, Chrousos GP, Zaloga G, Bokhari F, Vogeser M: Recommendations for the diagnosis and management of corticosteroid insufficiency in critically ill adult patients: Consensus statements from an international task force by the American College of Critical Care Medicine. Crit Care Med 2008; 36:1937-1949
6. Zaroff JG, Rosengard BR, Armstrong WF, Babcock WD, D'Alessandro A, Dec GW, Edwards NM, Higgins RS, Je-evanandum V, Kauffman M, Kirklin JK, Large SR, Marelli D, Peterson TS, Ring WS, Robbins RC, Russell SD, Taylor DO, Van Bakel A, Wallwork J, Young JB: Consensus conference report: Maximizing use of organs recovered from the cadaver donor: Cardiac recommendations, March 28-29, 2001, Crystal City, VA. Circulation 2002; 106:836-841
7. Vinclair M, Broux C, Faure P, Brun J, Genty C, Jacquot C, Chabre O, Payen JF: Duration of adrenal inhibition following a single dose of etomidate in critically ill patients. Intensive Care Med 2008; 34:714-719
8. De Backer D, Taccone FS, Holsten R, Ibrahimi F, Vincent JL: Influence of respiratory rate on stroke volume variation in mechanically ventilated patients. ANESTHESIOLOGY 2009; 110:1092-1097
9. Magder S: Clinical usefulness of respiratory variations in arterial pressure. Am J Respir Crit Care Med 2004; 169: 151-155 (Pubitemid 38114527)
10. Preisman S, Kogan S, Berkenstadt H, Perel A: Predicting fluid responsiveness in patients undergoing cardiac surgery: Functional haemodynamic parameters including the Respiratory Systolic Variation Test and static preload indicators. Br J Anaesth 2005; 95:746-755
11. Wood KE, Becker BN, McCartney JG, D'Alessandro AM, Coursin DB: Care of the potential organ donor. N Engl J Med 2004; 351:2730-2739
12. Guesde R, Barrou B, Leblanc I, Ourahma S, Goarin J-P, Coriat P, Riou B: Administration of desmopressin in brain-dead donors and renal function in kidney recipients. Lancet 1998; 352:1178-1181 (Pubitemid 28458532)
13. Cooper MS, Stewart PM: Corticosteroid insufficiency in acutely ill patients. N Engl J Med 2003; 348:727-734
14. Dimopoulou I, Tsagarakis S, Anthi A, Milou E, Ilias I, Stavrakaki K, Charalambidis C, Tzanela M, Orfanos S, Man-dragos K, Thalassinos N, Roussos C: High prevalence of decreased cortisol reserve in brain-dead potential organ donors. Crit Care Med 2003; 31:1113-1117
15. Novitzky D, Cooper DK, Reichart B: Hemodynamic and metabolic responses to hormonal therapy in brain-dead potential organ donors. Transplantation 1987; 43:852-854
16. Gramm HJ, Meinhold H, Bickel U, Zimmermann J, von Hammerstein B, Keller F, Dennhardt R, Voigt K: Acute endocrine failure after brain death? Transplantation 1992; 54:851-857
17. Powner DJ, Hendrich A, Lagler RG, Ng RH, Madden RL: Hormonal changes in brain dead patients. Crit Care Med 1990; 18:702-708
18. Lopau K, Mark J, Schramm L, Heidbreder E, Wanner C: Hormonal changes in brain death and immune activation in the donor. Transpl Int 2000; 13(suppl 1):S282-5
19. Howlett TA, Keogh AM, Perry L, Touzel R, Rees LH: Anterior and posterior pituitary function in brain-stem-dead donors. A possible role for hormonal replacement therapy. Transplantation 1989; 47:828-834
20. Novitzky D, Cooper DK, Muchmore JS, Zuhdi N: Pituitary function in brain-dead patients. Transplantation 1989; 48: 1078-1079
21. Annane D, Sebille V, Troche G, Raphael J-C, Gajdos P, Bellissant E: A 3-level prognostic classification in septic shock based on cortisol levels and cortisol response to corticotropin. JAMA 2000; 283:1038-1045
22. Annane D, Sebille V, Charpentier C, Bollaert P-E, Francois B, Korach J-M, Capellier G, Cohen Y, Azoulay E, Troche G, Chaumet-Riffaut P, Bellissant E: Effect of treatment with low doses of hydrocortisone and fludrocortisone on mortality in patients with septic shock. JAMA 2002; 288:862-871
23. Sprung CL, Annane D, Keh D, Moreno R, Singer M, Freivogel K, Weiss YG, Benbenishty J, Kalenka A, Forst H, Laterre P-F, Rein-hart K, Cuthbertson BH, Payen D, Briegel J; CORTICUS Study Group: Hydrocortisone therapy for patients with septic shock. N Engl J Med 2008; 358:111-124
24. Bollaert PE, Charpentier C, Levy B, Debouverie M, Audib-ert G, Larcan A: Reversal of late septic shock with supra-physiologic doses of hydrocortisone. Crit Care Med 1998; 26:645-650
25. de Jong M, Beishuizen A, Spijkstra J-J, Girbes A, Strack van Schijndel R, Twisk J, Groeneveld ABJ: Predicting a low cortisol response to adrenocorticotrophic hormone in the critically ill: A retrospective cohort study. Crit Care 2007; 11:R61
26. Barnes PJ: Beta-adrenergic receptors and their regulation. Am J Respir Crit Care Med 1995; 152:838-860
27. Walker BR, Williams BC: Corticosteroids and vascular tone: Mapping the messenger maze. Clin Sci (Lond) 1992; 82:597-605
28. Silverman HJ, Penaranda R, Orens JB, Lee NH: Impaired beta-adrenergic receptor stimulation of cyclic adenosine monophosphate in human septic shock: Association with myocardial hyporesponsiveness to catecholamines. Crit Care Med 1993; 21:31-39
29. Shivalkar B, Van Loon J, Wieland W, Tjandra-Maga TB, Borgers M, Plets C, Flameng W: Variable effects of explosive or gradual increase of intracranial pressure on myo-cardial structure and function. Circulation 1993; 87:230-239
30. McMillan M, Chernow B, Roth BL: Hepatic alpha 1-adrenergic receptor alteration in a rat model of chronic sepsis. Circ Shock 1986; 19:185-193
31. Saito T, Fuse A, Gallagher ET, Cutler S, Takanashi M, Yamada K, Carlsson C, Carney E, Abou-Sayf FK, Ogawa R: The effect of methylprednisolone on myocardial beta-ad-renergic receptors and cardiovascular function in shock patients. Shock 1996; 5:241-246
32. Amado JA, Lopez-Espadas F, Vazquez-Barquero A, Salas E, Riancho JA, Lopez-Cordovilla JJ, Garcia-Unzueta MT: Blood levels of cytokines in brain-dead patients: Relationship with circulating hormones and acute-phase reactants. Metabolism 1995; 44:812-816
33. Birks EJ, Burton PBJ, Owen V, Mullen AJ, Hunt D, Banner NR, Barton PJR, Yacoub MH: Elevated tumor necrosis factor-alpha and interleukin-6 in myocardium and serum of malfunctioning donor hearts. Circulation 2000; 102: III352-8
34. McLean KM, Duffy JY, Pandalai PK, Lyons JM, Bulcao CF, Wagner CJ, Akhter SA, Pearl JM: Glucocorticoids alter the balance between pro-and anti-inflammatory mediators in the myocardium in a porcine model of brain death. J Heart Lung Transplant 2007; 26:78-84
35. Santise G, D'Ancona G, Falletta C, Pirone F, Sciacca S, Turrisi M, Biondo D, Pilato M: Donor pharmacological hemodynamic support is associated with primary graft failure in human heart transplantation. Interact Cardiovasc Thorac Surg 2009; 9:476-479
36. Hamrahian AH, Oseni TS, Arafah BM: Measurements of serum free cortisol in critically ill patients. N Engl J Med 2004; 350:1629-1638