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Volumn 60, Issue 3, 2009, Pages 115-123

Evaluation of the predictive value of topoisomerase II α in patients with breast carcinoma

Author keywords

Breast carcinoma; Topoisomerase II

Indexed keywords

ANTHRACYCLINE; ANTINEOPLASTIC AGENT; DNA BINDING PROTEIN; DNA TOPOISOMERASE (ATP HYDROLYSING); DNA TOPOISOMERASE II ALPHA; TUMOR ANTIGEN; TUMOR MARKER;

EID: 77951643335     PISSN: 12339687     EISSN: None     Source Type: Journal    
DOI: None     Document Type: Review
Times cited : (7)

References (48)
  • 2
    • 0030962254 scopus 로고    scopus 로고
    • Relationship between lethal effects and topoisomerase II-mediated double-stranded DNA breaks produced by anthracyclines with different sequence specificity
    • Binaschi M, Capranico G, Dal Bo L, et al. Relationship between lethal effects and topoisomerase II-mediated double-stranded DNA breaks produced by anthracyclines with different sequence specificity. Mol Pharmacol 1997; 51: 1053-1059.
    • (1997) Mol Pharmacol , vol.51 , pp. 1053-1059
    • Binaschi, M.1    Capranico, G.2    Dal Bo, L.3
  • 3
    • 0034660851 scopus 로고    scopus 로고
    • In vivo site specificity and human isoenzyme selectivity of two topoisomerase II-poisoning anthracyclines
    • Binaschi M, Farinosi R, Borgetto ME, et al. In vivo site specificity and human isoenzyme selectivity of two topoisomerase II-poisoning anthracyclines. Cancer Res 2000; 60: 3770-3776.
    • (2000) Cancer Res , vol.60 , pp. 3770-3776
    • Binaschi, M.1    Farinosi, R.2    Borgetto, M.E.3
  • 4
    • 77952130185 scopus 로고    scopus 로고
    • Olszewski WP, Mrozkowiak A, Suszylo K, et al. Oznaczanie statusu genów TOPA 2 i HER 2 w raku piersi metoda̧. fluorescencyjnej hybrydyzacji in situ (FISH). Zakład Patologii Centrum Onkologii w Warszawie. Klinika Nowotworów Piersi i Chirurgii Rekonstrukcyjnej Centrum Onkologii w Warszawie. Program Badań - zadanie wieloletnie 2006.
    • Olszewski WP, Mrozkowiak A, Suszylo K, et al. Oznaczanie statusu genów TOPA 2 i HER 2 w raku piersi metoda̧. fluorescencyjnej hybrydyzacji in situ (FISH). Zakład Patologii Centrum Onkologii w Warszawie. Klinika Nowotworów Piersi i Chirurgii Rekonstrukcyjnej Centrum Onkologii w Warszawie. Program Badań - zadanie wieloletnie 2006.
  • 5
    • 33846093647 scopus 로고    scopus 로고
    • Molekularne mechanizmy działania antracyklin.
    • Szulawska A, Czyż M. Molekularne mechanizmy działania antracyklin. Postȩpy Higieny Dośw 2006; 60: 78-100.
    • (2006) Postȩpy Higieny Dośw , vol.60 , pp. 78-100
    • Szulawska, A.1    Czyż, M.2
  • 6
    • 0035092216 scopus 로고    scopus 로고
    • Functional and regulatory characteristics of eukaryotic type II DNA topoisomerase (review)
    • Bakshi RP, Galande S, Muniyappa K. Functional and regulatory characteristics of eukaryotic type II DNA topoisomerase (review). Crit Rev Biochem Mol Biol 2001; 36: 1-37.
    • (2001) Crit Rev Biochem Mol Biol , vol.36 , pp. 1-37
    • Bakshi, R.P.1    Galande, S.2    Muniyappa, K.3
  • 7
    • 0346244037 scopus 로고    scopus 로고
    • The favorable prognostics impact of tissue inhibitor of matrix metalloproteinases - 1 protein overexpression in breast cancer cells
    • Nakopoulou L, Giannopoulou I, Lazaris Ch, et al. The favorable prognostics impact of tissue inhibitor of matrix metalloproteinases - 1 protein overexpression in breast cancer cells. APIMS 2003; 111: 1027-1036.
    • (2003) APIMS , vol.111 , pp. 1027-1036
    • Nakopoulou, L.1    Giannopoulou, I.2    Lazaris, C.3
  • 8
    • 0001273935 scopus 로고    scopus 로고
    • Pharmacology of cancer chemotherapy. Topoisomerase interactive agents
    • De Vita, et al, eds, Philadelphia
    • Steward C, Ratain M. Pharmacology of cancer chemotherapy. Topoisomerase interactive agents. In: Principles and Practice in Oncology. De Vita, et al. (eds). Philadelphia 2001; 415-418.
    • (2001) Principles and Practice in Oncology , pp. 415-418
    • Steward, C.1    Ratain, M.2
  • 9
    • 77952206688 scopus 로고    scopus 로고
    • Coamplification of HER2 and topa 2 alpha genes in selected cases of breast carcinoma
    • Olszewski WP, Mrozkowiak A, Kosińska-Bauer, et al. Coamplification of HER2 and topa 2 alpha genes in selected cases of breast carcinoma. Pol J Pathol 2007; 2: 130.
    • (2007) Pol J Pathol , vol.2 , pp. 130
    • Olszewski, W.P.1    Mrozkowiak, A.2    Bauer, K.3
  • 10
    • 19644388869 scopus 로고    scopus 로고
    • HER 2/neu and Topoisomerase II alpha Gene Amplification and Protein Expression in Invasive Breast Carcinomas
    • Bhargava R, Lal P, Chen B, et al. HER 2/neu and Topoisomerase II alpha Gene Amplification and Protein Expression in Invasive Breast Carcinomas. Am J Clin Pathol 2005; 123: 889-895.
    • (2005) Am J Clin Pathol , vol.123 , pp. 889-895
    • Bhargava, R.1    Lal, P.2    Chen, B.3
  • 11
    • 0038792812 scopus 로고    scopus 로고
    • Agreement between chromogenic in situ hybridization (CISH) and FISH in the determination of HER 2 status in breast cancer
    • Arnould L, Denoux Y, MacGrogan G, et al. Agreement between chromogenic in situ hybridization (CISH) and FISH in the determination of HER 2 status in breast cancer. Br J Cancer 2003; 88: 1587-91.
    • (2003) Br J Cancer , vol.88 , pp. 1587-1591
    • Arnould, L.1    Denoux, Y.2    MacGrogan, G.3
  • 12
    • 3242738263 scopus 로고    scopus 로고
    • Interlaboratory comparison of HER - 2 oncogene amplification as detected by chromogenic and fluorescence in situ hybridization
    • Isola J, Tanner M, Forsyth A, et al. Interlaboratory comparison of HER - 2 oncogene amplification as detected by chromogenic and fluorescence in situ hybridization. Clin Cancer Res 2004; 10: 4793-4798.
    • (2004) Clin Cancer Res , vol.10 , pp. 4793-4798
    • Isola, J.1    Tanner, M.2    Forsyth, A.3
  • 13
    • 1542343905 scopus 로고    scopus 로고
    • Amplification of the TOP2A gene does not predict high levels of topoisomerase II alfa protein in human breast tumor samples
    • Mueller R. Amplification of the TOP2A gene does not predict high levels of topoisomerase II alfa protein in human breast tumor samples, genes, Chromosomes. Cancer 2004, 39: 288-297.
    • (2004) genes, Chromosomes. Cancer , vol.39 , pp. 288-297
    • Mueller, R.1
  • 14
    • 1442265950 scopus 로고    scopus 로고
    • Olsen KE, Knudsen H, Rasmussen BB, et al. and Danish Breast Cancer Cooperative Group: Amplification of HER 2 and TOP 2A and deletion of TOP2A genes in breast cancer investigated by new FISH probes. Acta Oncol 2004; 43: 35-42.
    • Olsen KE, Knudsen H, Rasmussen BB, et al. and Danish Breast Cancer Cooperative Group: Amplification of HER 2 and TOP 2A and deletion of TOP2A genes in breast cancer investigated by new FISH probes. Acta Oncol 2004; 43: 35-42.
  • 15
    • 77952220727 scopus 로고    scopus 로고
    • HER2 status in breast carcinoma - practical information for physicians. Nowa Medycyna - Badania nad rakiem
    • Olszewski WP. HER2 status in breast carcinoma - practical information for physicians. Nowa Medycyna - Badania nad rakiem. 2005; 1.
    • (2005) , pp. 1
    • Olszewski, W.P.1
  • 16
    • 16644362006 scopus 로고    scopus 로고
    • Correlation between topoisomerase II alpha gene amplification and protein expression in HER 2 amplified breast cancer
    • Durbeq V, Leo A, Cardoso F, et al. Correlation between topoisomerase II alpha gene amplification and protein expression in HER 2 amplified breast cancer. Int Oncol 2004; 25: 1473-1479.
    • (2004) Int Oncol , vol.25 , pp. 1473-1479
    • Durbeq, V.1    Leo, A.2    Cardoso, F.3
  • 18
    • 0033870292 scopus 로고    scopus 로고
    • Amplification and deletion of topoisomerase II alpha associate with ErbB-2 amplification and affect sensitivity to topoisomerase II inhibitor doxorubicin in breast cancer
    • Jarvinen TA, Tanner M, Rantanen V, et al. Amplification and deletion of topoisomerase II alpha associate with ErbB-2 amplification and affect sensitivity to topoisomerase II inhibitor doxorubicin in breast cancer. Am J Pathol 2000; 156: 839-847.
    • (2000) Am J Pathol , vol.156 , pp. 839-847
    • Jarvinen, T.A.1    Tanner, M.2    Rantanen, V.3
  • 19
    • 0028927502 scopus 로고    scopus 로고
    • Interphase cytogenetic analysis of ERBB2 and TOP2A co-amplification in invasive breast cancer and polysomy of chromosome 17 in ductal carcinoma in situ
    • Murphy DS, McHardy P, Coutts J, et al. Interphase cytogenetic analysis of ERBB2 and TOP2A co-amplification in invasive breast cancer and polysomy of chromosome 17 in ductal carcinoma in situ. Int J Cancer 1996; 64: 18-26.
    • (1996) Int J Cancer , vol.64 , pp. 18-26
    • Murphy, D.S.1    McHardy, P.2    Coutts, J.3
  • 20
    • 33746746400 scopus 로고    scopus 로고
    • TOP 2A and HER 2 gene amplification as predictors of response to anthracycline treatment in breast cancer
    • Villman K, Stahl E, Liljegren G, et al. TOP 2A and HER 2 gene amplification as predictors of response to anthracycline treatment in breast cancer. Acta Oncologica 2006; 45: 590-596.
    • (2006) Acta Oncologica , vol.45 , pp. 590-596
    • Villman, K.1    Stahl, E.2    Liljegren, G.3
  • 21
    • 18544370405 scopus 로고    scopus 로고
    • Predictive molecular markers in the adjuvant therapy of breast cancer: State of the art in year 2002
    • Di Leo A, Cardoso F, Durbecq V, et al. Predictive molecular markers in the adjuvant therapy of breast cancer: state of the art in year 2002. Int J Clin Oncol 2002; 245-253.
    • (2002) Int J Clin Oncol , pp. 245-253
    • Di Leo, A.1    Cardoso, F.2    Durbecq, V.3
  • 22
    • 0036091354 scopus 로고    scopus 로고
    • HER 2 amplification and topoisomerase II alpha gene aberrations as predictive markers in node-positive breast cancer patients randomly treated either with an anthracycline-based therapy or with cyclophosphamide, methotrexate and 5-fluorouracil
    • Di Leo A, Gancberg D, Larsimont D, et al. HER 2 amplification and topoisomerase II alpha gene aberrations as predictive markers in node-positive breast cancer patients randomly treated either with an anthracycline-based therapy or with cyclophosphamide, methotrexate and 5-fluorouracil. Clin Cancer Res 2002; 8: 1107-1116.
    • (2002) Clin Cancer Res , vol.8 , pp. 1107-1116
    • Di Leo, A.1    Gancberg, D.2    Larsimont, D.3
  • 23
    • 0034900175 scopus 로고    scopus 로고
    • Induction of topoisomerase II activity after ErbB-2 activation is associated with a differential response to breast cancer chemotherapy
    • Harris LN, Yang L, Liotcheva V, et al. Induction of topoisomerase II activity after ErbB-2 activation is associated with a differential response to breast cancer chemotherapy. Clin Cancer Res 2001; 7: 1497-1504.
    • (2001) Clin Cancer Res , vol.7 , pp. 1497-1504
    • Harris, L.N.1    Yang, L.2    Liotcheva, V.3
  • 24
    • 77952200421 scopus 로고    scopus 로고
    • Simultaneous assessment of amplification and expression of the ERBB2 and topo 2 alpha genes using FISH and immunohistochemistry in women with breast cancer
    • Śnietura M, Ponikiewska D, Liszka J, et al. Simultaneous assessment of amplification and expression of the ERBB2 and topo 2 alpha genes using FISH and immunohistochemistry in women with breast cancer. Pol J Pathol 2007; 2: 150.
    • (2007) Pol J Pathol , vol.2 , pp. 150
    • Śnietura, M.1    Ponikiewska, D.2    Liszka, J.3
  • 25
    • 21044448678 scopus 로고    scopus 로고
    • Predictive value of apoptosis, proliferation HER 2 and topoisomerase II alpha for anthracycline chemotherapy in locally advanced breast cancer
    • Arpino G, Ciocca DR, Weiss H, et al. Predictive value of apoptosis, proliferation HER 2 and topoisomerase II alpha for anthracycline chemotherapy in locally advanced breast cancer. Breast Cancer Res Treat 2005; 92: 69-75.
    • (2005) Breast Cancer Res Treat , vol.92 , pp. 69-75
    • Arpino, G.1    Ciocca, D.R.2    Weiss, H.3
  • 26
    • 3843120055 scopus 로고    scopus 로고
    • Correlation between complete response to anthracycline - based chemotherapy and topoisomerase II alpha gene amplification and protein overexpression in locally advanced/metastatic breast cancer
    • Cardoso F, Durbecq V, Larsimont D, et al. Correlation between complete response to anthracycline - based chemotherapy and topoisomerase II alpha gene amplification and protein overexpression in locally advanced/metastatic breast cancer. Int J Oncol 2004; 24: 201-209.
    • (2004) Int J Oncol , vol.24 , pp. 201-209
    • Cardoso, F.1    Durbecq, V.2    Larsimont, D.3
  • 27
    • 0036554731 scopus 로고    scopus 로고
    • Amplification and overexpression of topoisomerase IIalpha predict response to anthracycline-based therapy in locally advanced breast cancer
    • Coon JS, Marcus E, Gupta-Burt S, et al. Amplification and overexpression of topoisomerase IIalpha predict response to anthracycline-based therapy in locally advanced breast cancer. Clin Cancer Res 2002; 8: 1061-1067.
    • (2002) Clin Cancer Res , vol.8 , pp. 1061-1067
    • Coon, J.S.1    Marcus, E.2    Gupta-Burt, S.3
  • 28
    • 0141614011 scopus 로고    scopus 로고
    • Topoisomerase II alpha as a marker predicting the efficacy of anthracyclines in breast cancer: Are we at the end of the beginning?
    • Di Leo A, Isola J. Topoisomerase II alpha as a marker predicting the efficacy of anthracyclines in breast cancer: Are we at the end of the beginning? Clin Breast Cancer 2003; 4: 179-186.
    • (2003) Clin Breast Cancer , vol.4 , pp. 179-186
    • Di Leo, A.1    Isola, J.2
  • 29
    • 17944375163 scopus 로고    scopus 로고
    • HER 2 and topoisomerase II alpha as predictive markers in a population of node-positive breast cancer patients randomly treated with adjuvant CMF or epirubicin plus cyclophosphamide
    • Di Leo A, Larsimont D, Gancberg D, et al. HER 2 and topoisomerase II alpha as predictive markers in a population of node-positive breast cancer patients randomly treated with adjuvant CMF or epirubicin plus cyclophosphamide. Ann Oncol 2001; 12: 1081-1089.
    • (2001) Ann Oncol , vol.12 , pp. 1081-1089
    • Di Leo, A.1    Larsimont, D.2    Gancberg, D.3
  • 30
    • 0001887732 scopus 로고    scopus 로고
    • Amplification of Topoisomerase II Alpha is a Strong Predictor of Response to Epirubicin - Based Chemotherapy in HER-2/neu-Positive Metastatic Breast Cancer
    • abstr 21
    • Isola JJ, Tanner M, Holli K, et al. Amplification of Topoisomerase II Alpha is a Strong Predictor of Response to Epirubicin - Based Chemotherapy in HER-2/neu-Positive Metastatic Breast Cancer. In: San Antonio Breast Cancer Symposium 2000; (abstr 21); 2000 (abstr 21).
    • (2000) San Antonio Breast Cancer Symposium 2000; (abstr , vol.21
    • Isola, J.J.1    Tanner, M.2    Holli, K.3
  • 31
    • 0033870292 scopus 로고    scopus 로고
    • Amplification and Deletion of Topoisomerase II alpha Associate with Erb-2 Amplification and Affect Sensitivity to Topoisomerase II alpha Inhibitor Doxorubicin in Breast Cancer
    • Järvinen TA, Tanner M, Barlund M, et al. Amplification and Deletion of Topoisomerase II alpha Associate with Erb-2 Amplification and Affect Sensitivity to Topoisomerase II alpha Inhibitor Doxorubicin in Breast Cancer. Am J Pathol 2000; 3: 839-846.
    • (2000) Am J Pathol , vol.3 , pp. 839-846
    • Järvinen, T.A.1    Tanner, M.2    Barlund, M.3
  • 32
    • 0036085460 scopus 로고    scopus 로고
    • Cellular roles of DNA topoisomerases a molecular perspective
    • Wang JC. Cellular roles of DNA topoisomerases a molecular perspective. Nat Rev Mol Cell Biol 2002; 3: 430-440.
    • (2002) Nat Rev Mol Cell Biol , vol.3 , pp. 430-440
    • Wang, J.C.1
  • 33
    • 77952227479 scopus 로고    scopus 로고
    • Topoisomerase II alpha - a fundamental prognostic factor in breast carcinoma
    • Hajduk M. Topoisomerase II alpha - a fundamental prognostic factor in breast carcinoma. Pol J Pathol 2009; 2: 67-75.
    • (2009) Pol J Pathol , vol.2 , pp. 67-75
    • Hajduk, M.1
  • 35
    • 77952231596 scopus 로고    scopus 로고
    • Breast cancer
    • Gospodarowicz MK ed, John Wiley and Sons, New Jersey
    • Hayes DF. Breast cancer. In: Prognostic Factors in Cancer. Gospodarowicz MK (ed.). John Wiley and Sons, New Jersey 2006; 27: 207-212.
    • (2006) Prognostic Factors in Cancer , vol.27 , pp. 207-212
    • Hayes, D.F.1
  • 36
    • 1642523633 scopus 로고    scopus 로고
    • Thioredoxin is associated with proliferation, p53 expression and negative estrogen and progesterone receptor status in breast carcinoma
    • Turunen N, Karihtala P, Mantyniemi A, et al. Thioredoxin is associated with proliferation, p53 expression and negative estrogen and progesterone receptor status in breast carcinoma. APMIS 2004; 112: 123-132.
    • (2004) APMIS , vol.112 , pp. 123-132
    • Turunen, N.1    Karihtala, P.2    Mantyniemi, A.3
  • 37
    • 77952229440 scopus 로고    scopus 로고
    • Siedlecki JA. Biologia molekularna nowotworów. In: Onkologia kliniczna. Krzakowski M (ed.). Borgis, Warszawa 2006; 61.
    • Siedlecki JA. Biologia molekularna nowotworów. In: Onkologia kliniczna. Krzakowski M (ed.). Borgis, Warszawa 2006; 61.
  • 38
    • 0032189276 scopus 로고    scopus 로고
    • Physiological regulation of eukaryotic topoisomerase II
    • Isaacs RJ, Davies SJ, Sandri MI, et al. Physiological regulation of eukaryotic topoisomerase II Biochem Biophys Acta 1998; 1400: 121-137.
    • (1998) Biochem Biophys Acta , vol.1400 , pp. 121-137
    • Isaacs, R.J.1    Davies, S.J.2    Sandri, M.I.3
  • 39
    • 0031775808 scopus 로고    scopus 로고
    • Predictive value of topoisomerase II alpha and other prognostic factors for epirubicin chemotherapy in advanced breast cancer
    • Järvinen TA, Holli K, Kuukasjarvi T, et al. Predictive value of topoisomerase II alpha and other prognostic factors for epirubicin chemotherapy in advanced breast cancer. Br J Cancer 1998; 77: 2267-2273.
    • (1998) Br J Cancer , vol.77 , pp. 2267-2273
    • Järvinen, T.A.1    Holli, K.2    Kuukasjarvi, T.3
  • 40
    • 3042740814 scopus 로고    scopus 로고
    • HER 2 expression in breast cancer primary tumours and corresponding metastases. Original data and literature review
    • Carlsson J, Nordgren H, Sjostrom J, et al. HER 2 expression in breast cancer primary tumours and corresponding metastases. Original data and literature review. Br J Cancer 2004; 90: 2344-2348.
    • (2004) Br J Cancer , vol.90 , pp. 2344-2348
    • Carlsson, J.1    Nordgren, H.2    Sjostrom, J.3
  • 41
    • 0037333625 scopus 로고    scopus 로고
    • Topoisomerase II alpha (topo II) and HER 2 amplification in breast cancers and response to preoperative doxorubicin chemotherapy
    • Park K, Kim J, Lim S, et al. Topoisomerase II alpha (topo II) and HER 2 amplification in breast cancers and response to preoperative doxorubicin chemotherapy. Eur J Cancer 2003; 39: 631-634.
    • (2003) Eur J Cancer , vol.39 , pp. 631-634
    • Park, K.1    Kim, J.2    Lim, S.3
  • 42
    • 0035878845 scopus 로고    scopus 로고
    • Amplification of HER 2/neu and topoisomerase II? in primary and metastatic breast cancer
    • Tanner M, Järvinen P, Isola J. Amplification of HER 2/neu and topoisomerase II? in primary and metastatic breast cancer. Cancer Res 2001; 61: 5345-5348.
    • (2001) Cancer Res , vol.61 , pp. 5345-5348
    • Tanner, M.1    Järvinen, P.2    Isola, J.3
  • 43
    • 0031775808 scopus 로고    scopus 로고
    • Predictive value of topoisomerase II? and other prognostic factors for epirubicin chemotherapy in advanced breast cancer
    • Jarvinen TA, Holli K, Kuukasjarvi T, et al. Predictive value of topoisomerase II? and other prognostic factors for epirubicin chemotherapy in advanced breast cancer. Br J Cancer 1998; 72: 2267-2273.
    • (1998) Br J Cancer , vol.72 , pp. 2267-2273
    • Jarvinen, T.A.1    Holli, K.2    Kuukasjarvi, T.3
  • 44
    • 77952217977 scopus 로고    scopus 로고
    • The usefulness of fluorescent in situ hybridization (FISH) in the algorithm of diagnosis management in breast cancer
    • Mrozkowiak A, Olszewski WP, Suszylo K, et al. The usefulness of fluorescent in situ hybridization (FISH) in the algorithm of diagnosis management in breast cancer. Pol J Pathol 2007; 2: 128.
    • (2007) Pol J Pathol , vol.2 , pp. 128
    • Mrozkowiak, A.1    Olszewski, W.P.2    Suszylo, K.3
  • 45
    • 32944475493 scopus 로고    scopus 로고
    • Retrospective analysis of topoisometase II alpha amplifications and deletions predictive markers in primary breast cancer patients randomly assigned to cyclophosphamide, methotrexate, and fluorouracil or cyclophosphamide, epirubicin, and fluorouracil: Danish Breast Cancer Cooperative Group
    • Knoop AS, Knudsen H., Balslev E, et al. Retrospective analysis of topoisometase II alpha amplifications and deletions predictive markers in primary breast cancer patients randomly assigned to cyclophosphamide, methotrexate, and fluorouracil or cyclophosphamide, epirubicin, and fluorouracil: Danish Breast Cancer Cooperative Group. J Clin Oncol 2005; 23: 7483-7490.
    • (2005) J Clin Oncol , vol.23 , pp. 7483-7490
    • Knoop, A.S.1    Knudsen, H.2    Balslev, E.3
  • 46
    • 9144242764 scopus 로고    scopus 로고
    • Comparative value of tumour grade, hormonal receptors, Ki-67, HER-2 and topoisomerase II alpha status as predictive markers in breast cancer patients treated with neoadjuvant anthracycline-based chemotherapy
    • Petit T, Wilt M, Veiten M, et al. Comparative value of tumour grade, hormonal receptors, Ki-67, HER-2 and topoisomerase II alpha status as predictive markers in breast cancer patients treated with neoadjuvant anthracycline-based chemotherapy. Eur J Cancer 2004; 40: 205-211.
    • (2004) Eur J Cancer , vol.40 , pp. 205-211
    • Petit, T.1    Wilt, M.2    Veiten, M.3
  • 47
    • 0033006172 scopus 로고    scopus 로고
    • A critical evaluation of the mechanisms of action proposed for the antitumor effects of the anthracycline antibiotics adriamycin and daunorubicin
    • Gewirtz DA. A critical evaluation of the mechanisms of action proposed for the antitumor effects of the anthracycline antibiotics adriamycin and daunorubicin. Biochem Pharmacol 1999; 57: 727-741.
    • (1999) Biochem Pharmacol , vol.57 , pp. 727-741
    • Gewirtz, D.A.1
  • 48
    • 33744969590 scopus 로고    scopus 로고
    • Topoisomerase II A Gene amplification Predicts Favorable treatment Response to Tailored and Dose-Escalated Anthracycline - Based Adjuvant Chemotherapy in HER 2/neu - Amplified Breast Cancer. Scandinavian Breast Group Trial 9401
    • Tanner M, Järvinen P, Isola J. Topoisomerase II A Gene amplification Predicts Favorable treatment Response to Tailored and Dose-Escalated Anthracycline - Based Adjuvant Chemotherapy in HER 2/neu - Amplified Breast Cancer. Scandinavian Breast Group Trial 9401. J Clin Oncol 2006; 24: 2428-2438.
    • (2006) J Clin Oncol , vol.24 , pp. 2428-2438
    • Tanner, M.1    Järvinen, P.2    Isola, J.3


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