Antigenic variation in Treponema pallidum: TprK sequence diversity accumulates in response to immune pressure during experimental syphilis

Journal of Immunology

Volumn 184, Issue 7, 2010, Pages 3822-3829

  Giacani, Lorenzo ^a   Molini, Barbara J ^a   Kim, Eric Y ^a   Godornes, B Charmie ^a   Leader, B Troy ^a   Tantalo, Lauren C ^a   Centurion Lara, Arturo ^a   Lukehart, Sheila A ^a  

^a UNIVERSITY OF WASHINGTON   (United States)

Author keywords

[No Author keywords available]

Indexed keywords

EPITOPE; METHYLPREDNISOLONE ACETATE; PARASITE ANTIGEN; PROTEIN TPRK; SYNTHETIC PEPTIDE; UNCLASSIFIED DRUG; BACTERIAL ANTIGEN; BACTERIAL PROTEIN; BACTERIUM ANTIBODY; MAJOR OUTER SHEATH PROTEIN, TREPONEMA; MESSENGER RNA; PORIN;

ANIMAL EXPERIMENT; ANIMAL MODEL; ANTIGENIC VARIATION; ARTICLE; CONTROLLED STUDY; EXPERIMENTAL INFECTION; GENE; GENE CASSETTE; GENETIC RECOMBINATION; GENETIC VARIABILITY; HUMORAL IMMUNITY; IMMUNE DEFICIENCY; IMMUNE RESPONSE; IMMUNIZATION; IMMUNOCOMPETENCE; NONHUMAN; PERSISTENT INFECTION; PRIORITY JOURNAL; RABBIT; SYPHILIS; TPRK GENE; TREPONEMA PALLIDUM; AMINO ACID SEQUENCE; ANIMAL; DISEASE MODEL; GENETICS; IMMUNOLOGY; MOLECULAR GENETICS; NUCLEOTIDE SEQUENCE; REVERSE TRANSCRIPTION POLYMERASE CHAIN REACTION;

AMINO ACID SEQUENCE; ANIMALS; ANTIBODIES, BACTERIAL; ANTIGENIC VARIATION; ANTIGENS, BACTERIAL; BACTERIAL PROTEINS; BASE SEQUENCE; DISEASE MODELS, ANIMAL; MOLECULAR SEQUENCE DATA; PORINS; RABBITS; RECOMBINATION, GENETIC; REVERSE TRANSCRIPTASE POLYMERASE CHAIN REACTION; RNA, MESSENGER; SYPHILIS; TREPONEMA PALLIDUM;

EID: 77951633722     PISSN: 00221767     EISSN: 15506606     Source Type: Journal    
DOI: 10.4049/jimmunol.0902788     Document Type: Article

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