Effects of acute or chronic exposure to dietary organic anions on secretion of methotrexate and salicylate by Malpighian tubules of Drosophila melanogaster larvae

Archives of Insect Biochemistry and Physiology

Volumn 73, Issue 3, 2010, Pages 128-147

  Chahine, Sarah ^a   O'Donnell, Michael J ^a  

^a MCMASTER UNIVERSITY   (Canada)

Author keywords

Dietary toxins; Drosophila melanogaster larvae; Malpighian tubules; Methotrexate; Organic anion transport

Indexed keywords

DROSOPHILA MELANOGASTER;

ANION; DROSOPHILA PROTEIN; METHOTREXATE; SALICYLIC ACID DERIVATIVE;

ANIMAL; ARTICLE; DIET; DROSOPHILA MELANOGASTER; DRUG EFFECT; EPITHELIUM; GENE EXPRESSION REGULATION; LARVA; MALPIGHIAN TUBULE; METABOLISM; POLYMERASE CHAIN REACTION; SECRETION;

ANIMALS; ANIONS; DIET; DROSOPHILA MELANOGASTER; DROSOPHILA PROTEINS; EPITHELIUM; GENE EXPRESSION REGULATION; LARVA; MALPIGHIAN TUBULES; METHOTREXATE; POLYMERASE CHAIN REACTION; SALICYLATES;

EID: 77951627276     PISSN: 07394462     EISSN: 15206327     Source Type: Journal    
DOI: 10.1002/arch.20346     Document Type: Article

References (26)

1. +-ATPase in electrogenesis and epithelial transport in Malpighian tubules. J Exp Biol 203:1459-1468.
2. Bijelic G, Kim N, O'Donnell MJ. 2005. Effects of dietary or injected organic cations on larval Drosophila melanogaster: mortality and elimination of tetraethylammonium from the haemolymph. Arch Insect Biochem Physiol 60:93-103.
3. Borash DJ, Pierce VA, Gibbs AG, Mueller LD. 2000. Evolution of ammonia and urea tolerance in Drosophila melanogaster: resistance and cross-tolerance. J Insect Physiol 46:763-769.
4. Bresler VM, Belyaeva EA, Mozhayeva MG. 1990. A comparative study on the system of active transport of organic acids in Malpighian tubules of insects. J Insect Physiol 36:259-270.
5. Chahine S, O'Donnell MJ. 2009. Physiological and molecular characterization of methotrexate transport by Malpighian tubules of adult Drosophila melanogaster. J Insect Physiol 55: 927-935.
6. Chintapalli VR, Wang J, Dow JAT. 2007. Using FlyAtlas to identify better Drosophila models of human disease. Nature Genetics 39:715-720.
7. El-Sheikh AA, van den Heuvel JJ, Koenderink JB, Russel FG. 2007. Interaction of nonsteroidal anti-inflammatory drugs with multidrug resistance protein (MRP) 2/ABCC2- and MRP4/ABCC4-mediated methotrexate transport. J Pharmacol Exp Ther 320:229-235.
8. Graf U, Würgler FE, Katz AJ, Frei H, Juon H, Hall CB, Kale PG. 1984. Somatic mutation and recombination test in Drosophila melanogaster. Environ Mutagen 6:153-188.
9. Hahn GM, Li GC. 1990. Thermotolerance, thermoresistance, and thermosensitization. In: Morimoto RI, Tissieres A, Georgopoulos C, editors. Stress proteins in biology and medicine. Cold Spring Harbor, NY: Cold Spring Harbor Laboratory Press. p 79-100.
10. Leader JP, O'Donnell MJ. 2005. Transepithelial transport of fluorescent P-glycoprotein and MRP2 substrates by insect Malpighian tubules: confocal microscopic analysis of secreted fluid droplets. J Exp Biol 208:4363-4376.
11. Linton SM, O'Donnell MJ. 2000. Novel aspects of the transport of organic anions by the Malpighian tubules of Drosophila melanogaster. J Exp Biol 203:3575-3584.
12. Maddrell SHP, Gardiner BOC, Pilcher DEM, Reynolds SE. 1974. Active transport by insect Malpighian tubules of acidic dyes and of acylamides. J Exp Biol 61:357-377.
13. 2 and external buffering on ammonia excretion and Rhesus glycoprotein mRNA expression in rainbow trout. J Exp Biol 211:3226-3236.
14. Neufeld DSG, Kauffman R, Kurtz Z. 2005. Specificity of the fluorescein transport process in Malpighian tubules of the cricket Acheta domesticus. J Exp Biol 208:2227-2236.
15. O'Donnell MJ, Leader JP. 2006. Changes in fluid secretion rate alter net transepithelial transport of MRP2 and P-glycoprotein substrates in Malpighian tubules of Drosophila melanogaster. Arch Insect Biochem Physiol 63:123-134.
16. O'Donnell MJ, Rheault MR. 2005. Ion-selective microelectrode analysis of salicylate transport by the Malpighian tubules and gut of Drosophila melanogaster. J Exp Biol 208:93-104.
17. Rafaeli-Bernstein A, Mordue W. 1978. The transport of the cardiac glycoside ouabain by the Malpighian tubules of Zonocerus variegates. Physiol Entomol 3:59-63.
18. Rheault MR, O'Donnell MJ. 2004. Organic cation transport by Malpighian tubules of Drosophila melanogaster: application of two novel electrophysiological methods. J Exp Biol 207: 2173-2184.
19. Roberts DB, Stander GN. 1998. Drosophila: A practical approach. Oxford, UK: Oxford University Press.
20. Ruiz-Sanchez E, O'Donnell MJ. 2006. Characterization of salicylate uptake across the basolateral membrane of the Malpighian tubules of Drosophila melanogaster. J Insect Physiol 52:920-928.
21. Ruiz-Sanchez E, O'Donnell MJ. 2007a. Characterization of transepithelial transport of salicylate by the Malpighian tubules of Drosophila melanogaster and the effects of changes in fluid secretion rate. Physiol Entomol 32:157-166.
22. Ruiz-Sanchez E, O'Donnell MJ. 2007b. Effects of chronic exposure to dietary salicylate on elimination and renal excretion of salicylate by Drosophila melanogaster larvae. J Exp Biol 210:2464-2471.
23. Szeri F, Iliás A, Pomozi V, Robinow S, Bakos E, Váradi A. 2009. The high turnover Drosophila multidrug resistance-associated protein shares the biochemical features of its human orthologues. Biochim Biophys Acta 1788:402-409.
24. Wang J, Kean L, Yang J, Allan AK, Davies SA, Herzyk P, Dow JAT. 2004. Function-informed transcriptome analysis of Drosophila renal tubule. Genome Biol 5:R69.
25. Winegarden A, Wong S, Sopta M, Westwood J. 1996. Sodium salicylate decreases intracellular ATP, induces both heat shock factor binding and chromosomal puffing, but does not induce hsp 70 gene transcription in Drosophila. Am Soc Biochem Mol Biol 271:26971-26980.
26. Zimarino V, Wu C. 1987. Induction of sequence-specific binding of Drosophila heat shock activator protein without protein synthesis. Nature 327:727-730.