Prognostic Role of Loss of Heterozygosity on Chromosome 18 in Patients With Low-Risk Nonmuscle-Invasive Bladder Cancer: Results from a Prospective Study

Journal of Surgical Research

Volumn 161, Issue 1, 2010, Pages 89-94

  Cai, Tommaso ^a   Nesi, Gabriella ^a   Canto, Maurizio Dal ^a   Mondaini, Nicola ^a   Mauro Piazzini, ^a   Bartoletti, Riccardo ^a  

^a UNIVERSITY OF FLORENCE   (Italy)

Author keywords

bladder cancer; chromosome 18; LOH; microsatellite analysis; recurrence, outcome, urothelial carcinoma

Indexed keywords

ADULT; AGED; ARTICLE; ARTIFICIAL NEURAL NETWORK; BLADDER CANCER; BLOOD ANALYSIS; CANCER RECURRENCE; CANCER RISK; CHROMOSOME 18Q; CONTROLLED STUDY; CORRELATION ANALYSIS; DATA ANALYSIS; FEMALE; FOLLOW UP; HETEROZYGOSITY LOSS; HUMAN; KAPLAN MEIER METHOD; MAJOR CLINICAL STUDY; MALE; MULTIVARIATE ANALYSIS; PREDICTION; PRIORITY JOURNAL; PROBABILITY; PROGNOSIS; PROSPECTIVE STUDY; URINALYSIS;

AGED; AGED, 80 AND OVER; CARCINOMA; CHROMOSOMES, HUMAN, PAIR 18; FEMALE; HUMANS; LOSS OF HETEROZYGOSITY; MALE; MIDDLE AGED; MULTIVARIATE ANALYSIS; NEOPLASM RECURRENCE, LOCAL; NEURAL NETWORKS (COMPUTER); PROGNOSIS; PROSPECTIVE STUDIES; URINARY BLADDER NEOPLASMS;

EID: 77951621911     PISSN: 00224804     EISSN: 10958673     Source Type: Journal    
DOI: 10.1016/j.jss.2008.10.017     Document Type: Article

References (25)

1. Jemal A., Siegel R., Ward E., et al. Cancer Statistics, 2007. CA Cancer J Clin 57 (2007) 43
2. Sylvester R.J., van der Meijden A.P., Oosterlinck W., et al. Predicting recurrence and progression in individual patients with stage Ta T1 bladder cancer using EORTC risk tables: A combined analysis of 2596 patients from seven EORTC trials. Eur Urol 49 (2006) 466 discussion 475
3. Witjes J.A. Management of BCG failures in superficial bladder cancer: A review. Eur Urol 49 (2006) 790
4. Habuchi T., Marberger M., Droller M.J., et al. Prognostic markers for bladder cancer: International consensus panel on bladder tumor markers. Urology 66 6 Suppl 1 (2005) 64
5. Eissa S., Ali-Labib R., Swellam M., et al. Noninvasive diagnosis of bladder cancer by detection of matrix metalloproteinases (MMP-2 and MMP-9) and their inhibitor (TIMP-2) in urine. Eur Urol 52 (2007) 1388
6. Wu T.T., Chen J.H., Lee Y.H., et al. The role of bcl-2, p53, and ki-67 index in predicting tumor recurrence for low grade superficial transitional cell bladder carcinoma. J Urol 163 (2000) 758
7. Goldstein N.S., and Serrated p. and APC (conventional)-type colorectal polyps: Molecular-morphologic correlations, genetic pathways, and implications for classification. Am J Clin Pathol 125 (2006) 146
8. Saran K.K., Gould D., Godec C.J., et al. Genetics of bladder cancer. J Mol Med 74 (1996) 441
9. Turyn J., Matuszewski M., and Schlichtholz B. Genomic instability analysis of urine sediment versus tumor tissue in transitional cell carcinoma of the urinary bladder. Oncol Rep 15 (2006) 259
10. Bartoletti R., Cai T., Dal Canto M., et al. Multiplex polymerase chain reaction in microsatellite analysis urine sediment cells. A fast and cheap method in diagnosing and monitoring of superficial transitional bladder cell carcinoma. J Urol 175 (2006) 2032 discussion 2037
11. Bartoletti R., Dal Canto M., Cai T., et al. Early diagnosis and monitoring of superficial transitional cell carcinoma by microsatellite analysis on urine sediment. Oncol Rep 13 (2005) 531
12. Försti A., Louhelainen J., Söderberg M., et al. Loss of heterozygosity in tumor-adjacent normal tissue of breast and bladder cancer. Eur J Cancer 37 (2001) 1372
13. Kimura F., Florl A.R., Seifert H.H., et al. Destabilization of chromosome 9 in transitional cell carcinoma of the urinary bladder. Br J Cancer 85 (2001) 1887
14. Brandau S., and Böhle A. Bladder cancer. I. Molecular and genetic basis of carcinogenesis. Eur Urol 39 (2001) 491
15. Knowles M.A. What we could do now: Molecular pathology of bladder cancer. Mol Pathol 54 (2001) 215
16. Tzai T.S., Chen H.H., Chan S.H., et al. Clinical significance of allelotype profiling for urothelial carcinoma. Urology 62 (2003) 378
17. Uchida A., Tachibana M., Miyakawa A., et al. Microsatellite analysis in multiple chromosomal regions as a prognostic indicator of primary bladder cancer. Urol Res 28 (2000) 297
18. Oosterlinck W., Lobel B., Jakse G., et al. European Association of Urology (EAU) Working Group on Oncological Urology. Guidelines on bladder cancer. Eur Urol 41 (2002) 105
19. Polymeropoulos M.H., Xiao H., and Merril C.R. Tetranucleotide repeat polymorphism at the human myelin basic protein gene (MBP). Hum Mol Genet 1 (1992) 658
20. Cai T., Conti G., Lorenzini M., et al. Artificial intelligences in urological practice: The key to success?. Ann Oncol 18 (2007) 604
21. Cai T., Conti G., Nesi G., et al. Artificial intelligence for predicting recurrence-free probability of noninvasive high-grade urothelial bladder cell carcinoma. Oncol Rep 18 (2007) 959
22. Smith Jr. J.A., Labasky R.F., Cockett A.T.K., et al. Bladder cancer clinical guidelines panel summary report on the management of non-invasive bladder cancer (stage Ta, T1 and TIS). J Urol 162 (1999) 1697
23. Lassus H., Salovaara R., Aaltonen L.A., et al. Allelic analysis of serous ovarian carcinoma reveals two putative tumor suppressor loci at 18q22-q23 distal to SMAD4, SMAD2, and DCC. Am J Pathol 159 (2001) 35
24. Brewster S.F., Gingell J.C., Browne S., et al. Loss of heterozygosity on chromosome 18q is associated with muscle-invasive transitional cell carcinoma of the bladder. Br J Cancer 70 (1994) 697
25. Berger A.P., Parson W., Stenzl A., et al. Microsatellite alterations in human bladder cancer: Detection of tumor cells in urine sediment and tumor tissue. Eur Urol 41 (2002) 532