Probing the molecular recognition of a DNA·RNA hybrid duplex

Angewandte Chemie - International Edition

Volumn 49, Issue 18, 2010, Pages 3207-3210

  Wheelhouse, Richard T ^a   Garbett, Nichola C ^b   Buurma, Niklaas J ^c   Chaires, Jonathan B ^b  

^a UNIVERSITY OF BRADFORD   (United Kingdom)

^b UNIVERSITY OF LOUISVILLE   (United States)

^c CARDIFF UNIVERSITY   (United Kingdom)

Author keywords

DNA RNA hybrids; Drug discovery; Molecular recognition; Pyrimidine; RNaseH

Indexed keywords

BASE PAIRS; DNA-RNA HYBRIDS; DRUG DISCOVERY; HYBRID DUPLEX; INTERCALATIVE BINDING; LIGAND DESIGN; NEW DIRECTIONS; SEQUENCE SELECTIVITY; STRONG CORRELATION;

BINDING ENERGY; DNA; LIGANDS; MOLECULAR BIOLOGY; MOLECULAR RECOGNITION; RNA;

GENES;

DNA; LIGAND; POLYADENYLIC ACID; POLYURIDYLIC ACID; RNA;

ARTICLE; CHEMICAL STRUCTURE; CHEMISTRY; MOLECULAR PROBE; NUCLEIC ACID HYBRIDIZATION;

DNA; LIGANDS; MOLECULAR PROBES; MOLECULAR STRUCTURE; NUCLEIC ACID HYBRIDIZATION; POLY A; POLY U; RNA;

EID: 77951592511     PISSN: 14337851     EISSN: 15213773     Source Type: Journal    
DOI: 10.1002/anie.200907235     Document Type: Article

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