Extraction and analysis of β-sitosterol in herbal medicines

Journal of Medicinal Plants Research

Volumn 4, Issue 7, 2010, Pages 522-527

  Ye, Je Chiuan ^a   Chang, Wei Chun ^b   Hsieh, Dennis Jine Yuan ^a   Hsiao, Meen Woon ^a  

^a CHUNG SHAN MEDICAL UNIVERSITY   (Taiwan)

^b CHINA MEDICAL UNIVERSITY HOSPITAL   (Taiwan)

Author keywords

sitosterol; Hplc; Knoxia valerianoids; Soxhlet extraction

Indexed keywords

SITOSTEROL; VEGETABLE OIL;

ANALYTIC METHOD; ARTICLE; CONCENTRATION (PARAMETERS); CONTROLLED STUDY; DRUG DETERMINATION; DRUG ISOLATION; HERBAL MEDICINE; HIGH PERFORMANCE LIQUID CHROMATOGRAPHY; KNOXIA VALERIANOIDES; SPECIES DIFFERENCE;

GOSSYPIUM HIRSUTUM; KNOXIA; TRITICUM AESTIVUM;

EID: 77951466113     PISSN: 19960875     EISSN: 19960875     Source Type: Journal    
DOI: None     Document Type: Article

References (20)

1. Awad AB, Chan KC, Downie AC, Fink CS (2000). Peanuts as a source of beta-sitosterol, a sterol with anticancer properties. Nutr. Cancer. 36: 238-41.
2. Awad AB, Fink CS (2000). Phytosterols as anticancer dietary components: evidence and mechanism of Action 1,2. J. Nutr. 130: 2127-30.
3. Billheimer JT, Avart S, Milani BJ (1983). Separation of steryl esters by reversed-phase liquid chromatography. Lipid Res. 24: 1646-52.
4. Bouic PJD, Etsebeth S, Liebenberg RW, Albrecht CF, Pegel K, Van Jaarsveld PP (1996). Beta-sitosterol and Beta-sitosterol glucoside stimulate human peripheral blood lymphocyte proliferation: Implications for their use as an immunomodulatory vitamin combination. Int. J. Immunopharmac. 18: 693-700.
5. Burkhardt MR, ReVello RC, Smith SG, Zaugg SD (2005). Pressurized liquid extraction using water isopropanol coupled with solid-phase extraction cleanup for industrial and anthropogenic waste-indicator compounds in sediment. Analytica Chimica Acta. 534: 89-100.
6. Chen RR (1991). Plant oil. Biomedicine, Taipei Publishers, Taiwan. Pp. 283-287.
7. Cicero AF, Fiorito A, Panourgia MP, Sangiorgi Z, Gaddi A (2002). Effects of a new soy/beta-sitosterol supplement on plasma lipids in moderately hypercholesterolemic subjects. J. Am. Diet Assoc. 102: 1807-11.
8. Das S, Bhattacharya AK (1969). Chemical investigations on Knoxia corymbosa. J. Indian Chem. Soc. 1: 301-02.
9. Frank N, Andrews FM, Elliott SB, Lew J, Boston RC (2005). Effects of rice bran oil on plasma lipid concentrations, lipoprotein composition, and glucose dynamics in mares. J. Anim. Sci. 83: 2509-18.
10. Kalo P, Kuuranne T (2001). Analysis of free and esterified sterols in fats and oils by flash chromatography, gas chromatography and electrospray tandem mass spectrometry. J. Chromatogr. 935: 237-42.
11. Kamm W, Dionisi F, Fay LB, Hischenhuber C, Schmarr HG, Engel KH (2001). Analysis of steryl esters in cocoa butter by on-line liquid chromatography-gas chromatography. J. Chromatogr. A. 918: 341-45.
12. Kuksis A, Marai L, Myher JJ (1991). Plasma lipid profiling by liquid chromatography with chloride-attachment mass spectrometry. Lipids 26: 240-44.
13. Kuksis A, Myher JJ, Marai L, Little JA, McArhur RG, Roncari DA (1986). Fatty acid composition of individual plasma steryl esters in phytosterolemia and xanthomatosis. Lipids 21: 371-77.
14. Lin GD, Lin GP (1996). Chinese Medicine, Taipei Publishers, Taiwan. pp 188-189.
15. MacLatchy DL, Van Der Kraak GJ (1995). The phytoestrogen betasitosterol alters the reproductive endocrine status of goldfish. Toxicol Appl. Pharmacol. 134: 305-12.
16. Mezine I, Zhang H, Macku C, Lijana R (2003). Analysis of plant sterol and stanol esters in cholesterol-lowering spreads and beverages using high-performance liquid chromatography-atmospheric pressure chemical ionization-mass spectroscopy. J. Agric. Food Chem. 51: 5639-46.
17. Parcerisa J, Casals I, Boatella J, Codony R, Rafecas MJ (2000). Analysis of olive and hazelnut oil mixtures by high-performance liquid chromatography-atmospheric pressure chemical ionisation mass spectrometry of triacylglycerols and gas-liquid chromatography of non-saponifiable compounds (tocopherols and sterols). Chromatogr. A. 881: 149-54.
18. Tatu A, Miettinen A, Helena G (2002). Ineffective decrease of serum cholesterol by simvastatin in a subgroup of hypercholesterolemic coronary patients. Atherosclerosis 164: 147-52.
19. Zak A, Vecka M, Tvrzicka E, Hruby M, Novak F, Papezova H, Lubanda H, Vesela L, Stankova B (2005). Composition of Plasma Fatty Acids and Non-Cholesterol Sterols in Anorexia Nervosa. Physiol. Res. 54: 443-51.
20. Zhang X, Diane JD, Miesch M, Geoffroy P, Raul F, Roussi S, Dalal AW, Marchioni E (2005). Identification and quantitative analysis of sitosterol oxides in vegetable oils by capillary gas chromatographymass spectrometry. Steroids 6116: 1-11.