메뉴 건너뛰기




Volumn 33, Issue 5, 2010, Pages 467-472

Activated protein C attenuates acute lung injury and apoptosis in a hyperoxic animal model

Author keywords

Anticoagulant; Inflammatory mediators; Oxygen; Pathology; Pulmonary system

Indexed keywords

ACTIVATED PROTEIN C; ALBUMIN; DROTRECOGIN; INTERLEUKIN 1BETA; INTERLEUKIN 6; SODIUM CHLORIDE; TUMOR NECROSIS FACTOR ALPHA; AUTACOID; PROTEIN C;

EID: 77951454999     PISSN: 10732322     EISSN: None     Source Type: Journal    
DOI: 10.1097/SHK.0b013e3181c69213     Document Type: Article
Times cited : (19)

References (31)
  • 2
    • 40349098060 scopus 로고    scopus 로고
    • Procoagulant signaling mechanisms in lung inflammation and fibrosis: Novel opportunities for pharmacological intervention?
    • Chambers RC: Procoagulant signaling mechanisms in lung inflammation and fibrosis: novel opportunities for pharmacological intervention? Br J Pharmacol 153:S367YS378, 2008.
    • (2008) Br J Pharmacol , vol.153
    • Chambers, R.C.1
  • 4
    • 2942753923 scopus 로고    scopus 로고
    • Protein C/activated protein C pathway: Overview of clinical trial results in severe sepsis
    • Dhainaut JF, Yan SB, Claessens YE: Protein C/activated protein C pathway: overview of clinical trial results in severe sepsis. Crit Care Med 32:S194YS201, 2004.
    • (2004) Crit Care Med , vol.32
    • Dhainaut, J.F.1    Yan, S.B.2    Claessens, Y.E.3
  • 5
    • 27144451165 scopus 로고    scopus 로고
    • Disseminated intravascular coagulation in sepsis
    • DOI 10.1378/chest.128.4.2864
    • Zeerleder S, Hack CE, Wuillemin WA: Disseminated intravascular coagulation in sepsis. Chest 128:2864-2875, 2005. (Pubitemid 41507648)
    • (2005) Chest , vol.128 , Issue.4 , pp. 2864-2875
    • Zeerleder, S.1    Hack, C.E.2    Wuillemin, W.A.3
  • 8
    • 0030034186 scopus 로고    scopus 로고
    • Activated protein C attenuates endotoxin-induced pulmonary vascular injury by inhibiting activated leukocytes in rats
    • Murakami K, Okajima K, Uchiba M, Johno M, Nakagaki T, OkabeA H, Takatsuki K: ctivated protein C attenuates endotoxin-induced pulmonary vascular injury by inhibiting activated leukocytes in rats. Blood 87:642-647, 1996. (Pubitemid 26030319)
    • (1996) Blood , vol.87 , Issue.2 , pp. 642-647
    • Murakami, K.1    Okajima, K.2    Uchiba, M.3    Johno, M.4    Nakagaki, T.5    Okabe, H.6    Takatsuki, K.7
  • 11
    • 44349173646 scopus 로고    scopus 로고
    • Activated protein C attenuates intestinal reperfusion-induced acute lung injury: An experimental study in a rat model
    • DOI 10.1016/j.amjsurg.2007.06.025, PII S0002961008000469
    • Teke Z, Sacar M, Yenisey C, Atalay AO, Bicakci T, Erdem E: Activated protein C attenuates intestinal reperfusion-induced acute lung injury: an experimental study in a rat model. Am J Surg 195:861-873, 2008. (Pubitemid 351749444)
    • (2008) American Journal of Surgery , vol.195 , Issue.6 , pp. 861-873
    • Teke, Z.1    Sacar, M.2    Yenisey, C.3    Atalay, A.O.4    Bicakci, T.5    Erdem, E.6
  • 13
    • 17144390190 scopus 로고    scopus 로고
    • Drotrecogin alfa (activated) prevents smoke-induced increases in pulmonary microvascular permeability and proinflammatory cytokine IL-1β in rats
    • DOI 10.1007/s00408-004-2512-5
    • Wong SS, Sun NN, Hyde JD, Ruiz L, Meigs E, Herrin BR, Fastje CD, Macdonald SJ, Witten ML: Drotrecogin alfa (activated) prevents smoke-induced increases in pulmonary microvascular permeability and proinflamma-tory cytokine IL-1beta in rats. Lung 182:319-330, 2004. (Pubitemid 40685143)
    • (2004) Lung , vol.182 , Issue.6 , pp. 319-330
    • Wong, S.S.1    Sun, N.N.2    Hyde, J.D.3    Ruiz, L.4    Meigs, E.5    Herrin, B.R.6    Fastje, C.D.7    MacDonald, S.J.8    Witten, M.L.9
  • 14
    • 15944373891 scopus 로고    scopus 로고
    • Inhibition of nitric oxide synthase reverses the effect of albumin on lung damage in burn
    • Chen LW, Hwang YC, Wang JS, Chen JS, Hsu CM: Inhibition of nitric oxide synthase reverses the effect of albumin on lung damage in burn. J Am Coll Surg 200:574-583, 2005.
    • (2005) J Am Coll Surg , vol.200 , pp. 574-583
    • Chen, L.W.1    Hwang, Y.C.2    Wang, J.S.3    Chen, J.S.4    Hsu, C.M.5
  • 15
    • 2542441798 scopus 로고    scopus 로고
    • Rat pro-inflammatory cytokine and cytokine related mRNA quantification by real-time polymerase chain reaction using SYBR green
    • DOI 10.1186/1471-2172-5-3
    • Peinnequin A, Mouret C, Birot O, Alonso A, Mathieu J, Clarençon D, Agay D, Chancerelle Y, Multon E: A Rat pro-inflammatory cytokine and cytokine related mRNA quantification by real-time polymerase chain reaction using SYBR green. BMC Immunol 5:3, 2004. (Pubitemid 38692940)
    • (2004) BMC Immunology , vol.5 , pp. 3
    • Peinnequin, A.1    Mouret, C.2    Birot, O.3    Alonso, A.4    Mathieu, J.5    Clarencon, D.6    Agay, D.7    Chancerelle, Y.8    Multon, E.9
  • 16
    • 33947682834 scopus 로고    scopus 로고
    • Hyperoxia increases ventilator-induced lung injury via mitogen-activated protein kinases: A prospective, controlled animal experiment
    • Li LF, Liao SK, Ko YS, Lee CH, Quinn DA: Hyperoxia increases ventilator-induced lung injury via mitogen-activated protein kinases: a prospective, controlled animal experiment. Crit Care 11:R25, 2004.
    • (2004) Crit Care , vol.11
    • Li, L.F.1    Liao, S.K.2    Ko, Y.S.3    Ch, L.4    Quinn, D.A.5
  • 18
  • 20
    • 1542264188 scopus 로고    scopus 로고
    • The predictive role of serum and bronchoalveolar lavage cytokines and adhesion molecules for acute respiratory distress syndrome development and outcome
    • DOI 10.1186/rr193
    • Agouridakis P, Kyriakou D, Alexandrakis MG, Agouridakis P, Prekates A, Perisinakis K, Karkavitsas N, Bouros D: The predictive role of serum and bronchoalveolar lavage cytokines and adhesion molecules for acute respiratory distress syndrome development and outcome. Respir Res 3:25, 2002. (Pubitemid 41358111)
    • (2002) Respiratory Research , vol.3 , pp. 25
    • Agouridakis, P.1    Kyriakou, D.2    Alexandrakis, M.G.3    Prekates, A.4    Perisinakis, K.5    Karkavitsas, N.6    Bouros, D.7
  • 21
    • 25444459879 scopus 로고    scopus 로고
    • Inhibition of TNFalpha in vivo prevents hyperoxia-mediated activation of caspase 3 in type II cells
    • DOI 10.1186/1465-9921-6-10
    • Guthmann F, Wissel H, Schachtrup C, Tölle A, Rüdiger M, Spener F, Rüstow B: Inhibition of TNF alpha in vivo prevents hyperoxia-mediated activation of caspase 3 in type II cells. Respir Res 6:10, 2005. (Pubitemid 41358058)
    • (2005) Respiratory Research , vol.6 , pp. 10
    • Guthmann, F.1    Wissel, H.2    Schachtrup, C.3    Tolle, A.4    Rudiger, M.5    Spener, F.6    Rutow, B.7
  • 22
    • 0029979369 scopus 로고    scopus 로고
    • Biologic basis for interleukin-1 in disease
    • Dinarello CA: Biologic basis for interleukin-1 in disease. Blood 87:2095-2147, 1996.
    • (1996) Blood , vol.87 , pp. 2095-2147
    • Dinarello, C.A.1
  • 23
    • 0034967219 scopus 로고    scopus 로고
    • Transient expression of IL-1β induces acute lung injury and chronic repair leading to pulmonary fibrosis
    • Kolb M, Margetts PJ, Anthony DC, Pitossi F, Gauldie J: Transient expression of IL-1beta induces acute lung injury and chronic repair leading to pulmonary fibrosis. J Clin Invest 107:1529-1536, 2001. (Pubitemid 32574639)
    • (2001) Journal of Clinical Investigation , vol.107 , Issue.12 , pp. 1529-1536
    • Kolb, M.1    Margetts, P.J.2    Anthony, D.C.3    Pitossi, F.4    Gauldie, J.5
  • 25
    • 60549088133 scopus 로고    scopus 로고
    • The role of coagulation pathways and treatment with activated protein C in hyperoxic lung injury
    • Looney MR, Esmon CT, Matthay M: The role of coagulation pathways and treatment with activated protein C in hyperoxic lung injury. Thorax 64: 114-120, 2009.
    • (2009) Thorax , vol.64 , pp. 114-120
    • Looney, M.R.1    Esmon, C.T.2    Matthay, M.3
  • 26
    • 65849521772 scopus 로고    scopus 로고
    • Inhaled aerosolised recombinant human activated protein C ameliorates endotoxin-induced lung injury in anaesthetised sheep
    • Waerhaug K, Kuzkov VV, Kuklin VN, Mortensen R, Nordhus KC, Kirov MY, Bjertnaes LJ: Inhaled aerosolised recombinant human activated protein C ameliorates endotoxin-induced lung injury in anaesthetised sheep. Crit Care 13:R51, 2009.
    • (2009) Crit Care , vol.13
    • Waerhaug, K.1    Kuzkov, V.V.2    Kuklin, V.N.3    Mortensen, R.4    Nordhus, K.C.5    Kirov, M.Y.6    Bjertnaes, L.J.7
  • 27
    • 57449098600 scopus 로고    scopus 로고
    • Recombinant human activated protein C ameliorates oleic acid-induced lung injury in awake sheep
    • Waerhaug K, Kirov MY, Kuzkov VV, Kuklin VN, Bjertnaes LJ: Recombinant human activated protein C ameliorates oleic acid-induced lung injury in awake sheep. Crit Care 12:R146, 2008.
    • (2008) Crit Care , vol.12
    • Waerhaug, K.1    Kirov, M.Y.2    Kuzkov, V.V.3    Kuklin, V.N.4    Bjertnaes, L.J.5
  • 28
    • 0037394676 scopus 로고    scopus 로고
    • Neutrophils and acute lung injury
    • Abraham E: Neutrophils and acute lung injury. Crit Care Med 31:S195YS199, 2003. (Pubitemid 36458167)
    • (2003) Critical Care Medicine , vol.31 , Issue.SUPPL.
    • Abraham, E.1
  • 29
    • 0036009460 scopus 로고    scopus 로고
    • Blocking neutrophil influx reduces DNA damage in hyperoxia-exposed newborn rat lung
    • Auten RL, Whorton MH, Mason SN: Blocking neutrophil influx reduces DNA damage in hyperoxia-exposed newborn rat lung. Am J Respir Cell Mol Biol 26: 391-397, 2002.
    • (2002) Am J Respir Cell Mol Biol , vol.26 , pp. 391-397
    • Auten, R.L.1    Whorton, M.H.2    Mason, S.N.3


* 이 정보는 Elsevier사의 SCOPUS DB에서 KISTI가 분석하여 추출한 것입니다.