In vitro HIV type-1 reverse transcriptase inhibitory activity from leaf extracts of scoparia dulcis L.

Journal of Herbs, Spices and Medicinal Plants

Volumn 15, Issue 3, 2009, Pages 241-247

  Porika, Mahendar ^a   Aileni, Mahender ^a   Kokkirala, Venugopal Rao ^a   Gadidasu, Kranthi ^a   Umate, Pavan ^a   Rao, Allini V ^a   Devarakonda, Rama Krishna ^a   Abbagani, Sadanandam ^a  

^a KAKATIYA UNIVERSITY   (India)

Author keywords

Escobilla; Licorice weed; Medicinal plant; Plant extract; Scrophulariaceae; Sweet broomweed; Vassourinha; Zidovudine

Indexed keywords

RNA DIRECTED DNA POLYMERASE; RNA DIRECTED DNA POLYMERASE INHIBITOR; SCOPARIA DULCIS EXTRACT; ZIDOVUDINE;

DRUG; ENZYME ACTIVITY; HERB; HUMAN IMMUNODEFICIENCY VIRUS; INHIBITOR; MEDICINAL PLANT; METHANOL; PARAMETERIZATION; PLANT EXTRACT;

ARTICLE; CONTROLLED STUDY; DRUG ISOLATION; ENZYME INHIBITION; ENZYME INHIBITOR INTERACTION; HUMAN IMMUNODEFICIENCY VIRUS 1; IC 50; NONHUMAN; PLANT LEAF;

HUMAN IMMUNODEFICIENCY VIRUS 1; SCHINUS MOLLE; SCOPARIA; SCOPARIA DULCIS; SCROPHULARIACEAE;

EID: 77951433001     PISSN: 10496475     EISSN: 15403580     Source Type: Journal    
DOI: 10.1080/10496470903378854     Document Type: Article

References (22)

1. Aileni, M., V.R. Kokkirala, S.R. Kota, P. Umate, and S. Abbagani. 2008. Efficient in vitro regeneration from mature leaf explants of Scoparia dulcis L.-An ethnomedicinal plant. Journal of Herbs, Spices, & Medicinal Plants 14(3-4): 200-207.
2. Clark, A.M. 1996. Natural products as a resource for new drugs. Pharmaceut. Res. 13(8):1133-1144.
3. Djahanguiri, B. 1969. The production of acute gastric ulceration by indomethacin in the rat. Scand. J. Gastroenterol. 4(3):265-267.
4. Freire, S.M., J.A.S. Emim, A.J. Lapa, C. Souccar, and L.M.B. Torres. 1993. Analgesic and anti-inflammatory properties of Scoparia dulcis L. extracts and glutinol in rodents. Phytother. Res. 7(6):408-414. (Pubitemid 24005503)
5. Freire, S.M., L.M. Torres, N.F. Roque, C. Souccar, and A.J. Lapa. 1991. Analgesic activity of a triterpene isolated from Scoparia dulcis L. (Vassourinha). Mem. Inst. Oswaldo Cruz. 86(2):149-151.
6. Hayashi, T., M. Kawasaki, Y. Miwa, T. Taga, and N. Morita. 1990. Antiviral agents of plant origin. III. Scopadulin, a novel tetracyclic diterpene from Scoparia dulcis L. Chem. Pharmaceut. Bull. 38(4):945-947. (Pubitemid 20185801)
7. Hayashi, T., M. Kawasaki, K. Okamura, Y. Tamada, N. Morita, Y. Tezuka, T. Kikuchi, Y. Miwa, and T. Taga. 1992. Scoparic acid A, a beta-glucuronidase inhibitor from Scoparia dulcis. J. Nat Prod. 55:1748-1755. (Pubitemid 23023261)
8. Hayashi, K., S. Niwayama, T. Hayashi, R. Nago, H. Ochiai, and N. Morita. 1988. In vitro and in vivo antiviral activity of scopadulcic acid B from Scoparia dulcis, Scrophulariaceae, against herpes simplex virus type-1. Antivir. Res. 9(6): 345-354. (Pubitemid 19001082)
9. Houghton, P.J. 1996. Compounds with anti-HIV activity from plants. Trans. Roy. Soc. Trop. Med. Hyg. 90(6):601-604.
10. Kanyara, J.N. and E.N.M. Njagi. 2005. Anti-HIV-1 activities in extracts from some medical plants as assessed in an in vitro biochemical HIV-1 reverse transcriptase assay. Phytother. Res. 19(4):287-290.
11. Kawasaki, M., T. Hayashi, M. Arisawa, N. Morita, and L.H. Berganza. 1988. 8-Hydroxytricetin 7-glucuronide, a beta-glucuronidase inhibitor from Scoparia dulcis. Phytochemistry 27(11):3709-3711.
12. Kawasaki, M., T. Hayashi, M. Arisawa, M. Shimizu, S. Horie, H. Ueno, H. Syogawa, S. Suzuki, M. Yoshizaki, and N. Morita. 1987. Structure of scoparic acid A, a new labdane-type diterpenoid from a Paraguayan crude drug "Typycha Kuratu" (Scoparia dulcis L.). Chem. Pharm. Bull. 35(9):3963-3966. (Pubitemid 18077565)
13. Latha, M., L. Pari, S. Sitasawad, and R. Bhonde. 2004. Scoparia dulcis, a traditional antidiabetic plant, protects against streptozoticin-induced oxidative stress and apoptosis in vitro and in vivo. J. Biochem. Toxicol. 18(5):261-272. (Pubitemid 39463519)
14. Latha, M., K.M. Ramkumar, L. Pari, P.N. Damodaran, V. Rajeshkannan, and T. Suresh. 2006. Phytochemical and antimicrobial study of an antidiabetic plant: Scoparia dulcis L. J. Med. Food 9(3):391-394. (Pubitemid 44850725)
15. Menguy, R. and L. Desbaillets. 1967. Role of inhibition of gastric mucous secretion in the phenomenon of gastric mucosal injury by indomethacin. Am. J. Dig. Dis. 12(9):862-866.
16. Mesia-Vela, S., M. Bielavsky, L.M.B. Torres, S.M. Freire, M.T.R. Lima-Landman, C. Souccar, and A.J. Lapa. 2007. In vivo inhibition of gastric acid secretion by the aqueous extract of Scoparia dulcis L. in rodents. J. Ethnopharmacol. 111(2):403-408. (Pubitemid 46528087)
17. Nath, C.M. 1943. The new antidiabetic principle (amelin) occurring in nature I. Studies on some of its biochemical properties. Ann. Biochem. Exp. Med. 3:55-62.
18. Pascal O.B., L.O. Chikwelu, I. Eunice, A. Marie-Line, and L. Simon. 2004. In vitro activity of three selected South African medicinal plants against human immunodeficiency virus type-1 reverse transcriptase. Afr. J. Biotechnol. 3(10): 555-559.
19. Perry, L.M. 1980. Medicinal Plants of East and Southeast Asia: Attributed Properties and Uses, 1st ed. The MIT Press, Cambridge, MA.
20. Tan, G.T., J.M. Pezzuto, and A.D. Kinghorn. 1991. Evaluation of natural products as inhibitors of human immunodeficiency virus type-1 (HIV-1) reverse transcriptase. J. Nat. Prod. 54(1):143-154.
21. Uday Kiran, V., K. Radhika, P. Mahendar, A. Sadanandam, and D. Rama Krishna. 2008. Anti HIV-reverse transcriptase activity of some selected bioflavinoid. Adv. Pharmacol. Toxico. 9(1):71-76.
22. Warunya, W., S. Noppamas, and W. Chanpen. 2005. In vitro HIV type 1 reverse transcriptase inhibitory activities of Thai medicinal plants and Canna indica L. rhizomes. J. Ethnopharmacol. 101(1-3):84-89.