Adjuvant vs. salvage radiotherapy for pathologically advanced prostate cancer

Current Opinion in Urology

Volumn 20, Issue 3, 2010, Pages 229-233

  McVey, Gerard P ^a   Parker, Chris ^a  

^a INSTITUTE OF CANCER RESEARCH   (United Kingdom)

Author keywords

Adjuvant therapy; Prostate cancer; Prostatectomy; Radiotherapy; Salvage therapy

Indexed keywords

PROSTATE SPECIFIC ANTIGEN;

ANDROGEN DEPRIVATION THERAPY; CANCER ADJUVANT THERAPY; CANCER RADIOTHERAPY; CANCER RESEARCH; CANCER SURGERY; CANCER SURVIVAL; CLINICAL TRIAL; HIGH RISK PATIENT; HISTOPATHOLOGY; HUMAN; INTERMETHOD COMPARISON; MEDICAL SOCIETY; MORBIDITY; OVERALL SURVIVAL; POSTOPERATIVE CARE; PRIORITY JOURNAL; PROSTATE CANCER; PROSTATECTOMY; REVIEW; SALVAGE THERAPY;

HUMANS; MALE; NEOPLASM STAGING; PROSTATECTOMY; PROSTATIC NEOPLASMS; RADIOTHERAPY, ADJUVANT; SALVAGE THERAPY; TREATMENT OUTCOME;

EID: 77951294967     PISSN: 09630643     EISSN: None     Source Type: Journal    
DOI: 10.1097/MOU.0b013e3283383b6e     Document Type: Review

References (25)

1. Overgaard M, Hansen PS, Overgaard J, et al. Postoperative radiotherapy in high-risk premenopausal women with breast cancer who receive adjuvant chemotherapy. Danish Breast Cancer Cooperative Group 82b Trial. N Engl J Med 1997; 337:949-955.
2. Overgaard M, Jensen MB, Overgaard J, et al. Postoperative radiotherapy in high-risk postmenopausal breast-cancer patients given adjuvant tamoxifen: Danish Breast Cancer Cooperative Group DBCG 82c randomised trial. Lancet 1999; 353:1641-1648. (Pubitemid 29224519)
3. Forastiere A, Koch W, Trotti A, Sidransky D. Head and neck cancer. N Engl J Med 2001; 345:1890-1900. (Pubitemid 33716564)
4. Kapiteijn E, Marijnen CA, Nagtegaal ID, et al. Preoperative radiotherapy combined with total mesorectal excision for resectable rectal cancer. N Engl J Med 2001; 345:638-646. (Pubitemid 34066236)
5. Waggoner SE. Cervical cancer. Lancet 2003; 361:2217-2225.
6. Pound CR, Partin AW, Eisenberger MA, et al. Natural history of progression after PSA elevation following radical prostatectomy. JAMA 1999; 281:1591-1597. (Pubitemid 29211767)
7. Parker C, Sydes MR. Resolving the optimal timing of radiotherapy after radical prostatectomy: the need for further research. J Clin Oncol 2008; 26:e3.
8. Parker C, Sydes M. Adjuvant radiotherapy after surgery for prostate cancer. JAMA 2008; 300:2119; author reply.
9. Karakiewicz PI, Eastham JA, Graefen M, et al. Prognostic impact of positive surgical margins in surgically treated prostate cancer: multiinstitutional assessment of 5831 patients. Urology 2005; 66:1245-1250. (Pubitemid 41797299)
10. Han M, Partin AW, Zahurak M, et al. Biochemical (prostate specific antigen) recurrence probability following radical prostatectomy for clinically localized prostate cancer. J Urol 2003; 169:517-523. (Pubitemid 36132976)
11. Thompson IM, Tangen CM, Paradelo J, et al. Adjuvant radiotherapy for pathological T3N0M0 prostate cancer significantly reduces risk of metastases and improves survival: long-term followup of a randomized clinical trial. J Urol 2009; 181:956-962.
12. Wiegel T, Bottke D, Steiner U, et al. Phase III postoperative adjuvant radiotherapy after radical prostatectomy compared with radical prostatectomy alone in pT3 prostate cancer with postoperative undetectable prostate-specific antigen: ARO 96-02/AUO AP 09/95. J Clin Oncol 2009; 27:2924-2930.
13. Bolla M, van Poppel H, Collette L, et al. Postoperative radiotherapy after radical prostatectomy: a randomised controlled trial (EORTC trial 22911). Lancet 2005; 366:572-578. (Pubitemid 41140332)
14. Dearnaley DP. Additional treatment for pT3 prostate cancer: now, later or never. BJU Int 2007; 100:977-979.
15. Morgan SC, Waldron TS, Eapen L, et al. Adjuvant radiotherapy following radical prostatectomy for pathologic T3 or margin-positive prostate cancer: a systematic review and meta-analysis. Radiother Oncol 2008; 88:1-9.
16. Pasquier D, Ballereau C. Adjuvant and salvage radiotherapy after prostatectomy for prostate cancer: a literature review. Int J Radiat Oncol Biol Phys 2008; 72:972-979.
17. Mitra A, Khoo V. Adjuvant therapy after radical prostatectomy: clinical considerations. Surg Oncol 2009; 18:247-254.
18. Morgan SC, Dearnaley DP. Additional therapy for high-risk prostate cancer treated with surgery: what is the evidence? Expert Rev Anticancer Ther 2009; 9:939-951.
19. Van Cangh PJ, Richard F, Lorge F, et al. Adjuvant radiation therapy does not cause urinary incontinence after radical prostatectomy: results of a prospective randomized study. J Urol 1998; 159:164-166. (Pubitemid 27525595)
20. Thompson IM Jr, Tangen CM, Paradelo J, et al. Adjuvant radiotherapy for pathologically advanced prostate cancer: a randomized clinical trial. JAMA 2006; 296:2329-2335. (Pubitemid 44749360)
21. Hermanek P, Sobin LH. TNM classification of malignant tumours. ed. 4 Berlin, Germany: Springer; 1992.
22. Stephenson AJ, Scardino PT, Kattan MW, et al. Predicting the outcome of salvage radiation therapy for recurrent prostate cancer after radical prostatectomy. J Clin Oncol 2007; 25:2035-2041.
23. Trock BJ, Han M, Freedland SJ, et al. Prostate cancer-specific survival following salvage radiotherapy vs. observation in men with biochemical recurrence after radical prostatectomy. JAMA 2008; 299:2760-2769. (Pubitemid 351846851)
24. Parker C, Clarke N, Logue J, et al. RADICALS (Radiotherapy and Androgen Deprivation in Combination after Local Surgery). Clin Oncol 2007; 19:167-171. (Pubitemid 46275965)
25. Parker C, Sydes MR, Catton C, et al. Radiotherapy and androgen deprivation in combination after local surgery (RADICALS): a new Medical Research Council/National Cancer Institute of Canada phase III trial of adjuvant treatment after radical prostatectomy. BJU Int 2007; 99:1376-1379. (Pubitemid 47164815)