Hyperprolactinemia: Different clinical expression in childhood

Hormone Research in Paediatrics

Volumn 73, Issue 3, 2010, Pages 187-192

  Saranac, L ^a   Zivanovic, S ^a   Radovanovic, Z ^a   Kostic, G ^a   Markovic, I ^a   Miljkovic, P ^a  

^a University Clinical Center   (Serbia)

Author keywords

Hyperprolactinemia; Obesity; Prolactinoma; Short stature

Indexed keywords

DOPAMINE RECEPTOR STIMULATING AGENT; PROLACTIN;

ADOLESCENT; ARTICLE; BREAST DEVELOPMENT; CHILD; CHILDHOOD DISEASE; CLINICAL ARTICLE; DELAYED PUBERTY; DRUG EFFICACY; FEMALE; GYNECOMASTIA; HORMONE DETERMINATION; HUMAN; HYPERPROLACTINEMIA; HYPOGONADISM; HYPOPHYSIS TUMOR; HYPOTHALAMUS TUMOR; HYPOTHYROIDISM; MALE; OBESITY; OVARY CYST; OVARY POLYCYSTIC DISEASE; PRIORITY JOURNAL; PROLACTIN BLOOD LEVEL; PROLACTINOMA; SECONDARY AMENORRHEA; SHORT STATURE;

ADOLESCENT; AMENORRHEA; BROMOCRIPTINE; CHILD; CHILD, PRESCHOOL; FEMALE; HUMANS; HYPERPROLACTINEMIA; INFANT; MALE; POLYCYSTIC OVARY SYNDROME; PROLACTINOMA; PUBERTY, DELAYED;

EID: 77951290961     PISSN: 16632818     EISSN: 16632826     Source Type: Journal    
DOI: 10.1159/000284360     Document Type: Article

References (29)

1. Besser GM: Anterior pituitary; in Hall R, Besser M (ed): Fundamentals of Clinical Endocrinology, ed 4. Edinburgh, Churchill-Livingstone, 1989, pp 1-30.
2. Sommerfield AJ, Patrick AW: Hyperprolactinaemia. Diabetes Endocrinol 2005; 35: 143-147.
3. Massart F, Saggese G: Hyperprolactinaemia in children: a common diagnostic dilemma. Eur Endocr Rev 2006: 1-4.
4. Groote Veldman R, van den Berg G, Pincus SM, Frolich M, Veldhuis JD, Roelfsema F: Increased episodic release and disorderliness of prolactin secretion in both micro- and macroprolactinomas. Eur J Endocrinol 1999; 140: 192-200. (Pubitemid 29155576)
5. Petakov MS, Damjanovic SS, Nikolic-Durovic MM, Dragojlovic ZL, Obradovic S, Gligorovic MS, Simic MZ, Popovic VP: Pituitary adenomas secreting large amounts of prolactin may give false low values in immunoradiometric assays: the hook effect. J Endocrinol Invest 1998; 21: 184-188. (Pubitemid 28223066)
6. Zhang ZH, Zhuang L, Dufau ML: Prolactin receptor gene diversity: structure and regulation. Trends Endocrinol Metab 1998; 9: 94-102. (Pubitemid 28225927)
7. Yu-Lee LY: Molecular actions of prolactin in the immune system. Proc Soc Exp Biol Med 1997; 215: 35-52. (Pubitemid 27194678)
8. Doknic M, Pekic S, Zarkovic M, Medic-Stojanoska M, Dieguez C, Casaneuva F, Popovic V: Dopaminergic tone and obesity: an insight from prolactinomas treated with bromocriptine. Eur J Endocrinol 2002; 147: 77-84. (Pubitemid 34814743)
9. Gullu S: Prolactin: an underestimated hormone. Endocrine Abstracts (2008); 16. Bio-Scientifica. 10th European Congress of Endocrinology, Berlin, 2008.
10. Gold EB: Epidemiology of pituitary adenomas. Epidmiol Rev 1981; 3: 163-183.
11. Sakazume S, Obata K, Takahashi E, Yoshino A, Murakami N, Sakuta R, Murai T, Nagai T: Bromocriptine treatment of prolactinoma restores growth hormone secretion and causes catch-up growth in a prepubertal child. Eur J Pediatr 2004; 163: 472-474. (Pubitemid 39013121)
12. Oberfield SE, Nino M, Riddick L, Pang S, Nagel M, Khandji A, Kairam R, Levine LS: Combined bromocriptine and growth hormone (GH) treatment in GH-deficient children with macroprolactinoma in situ. J Clin Endocrinol Metab 1992; 75: 87-90.
13. Colao A, Di Sarno A, Cappabianca P, Bri ganti F, Pivonello R, Di Somma C, Faggiano A, Biondi B, Lombardi G: Gender differences in the prevalence, clinical features and response to carbergoline in hyperprolactinaemia. Eur J Endocrinol 2003; 148: 325-331. (Pubitemid 36410718)
14. Casanueva FF, Molitch ME, Schlechte JA, et al.: Guidelines of the Pituitary Society for the diagnosis and management of prolactinomas. Clin Endocrinol (Oxf) 2006; 65: 265-273. (Pubitemid 44079693)
15. Colao A, Loche S, Cappa M, Di Sarno A, Landi ML, Sarnacchiaro F, Facciolli G, Lombardi G: Prolactinomas in children and adolescents: clinical presentation and long term follow-up. J Clin Enocrinol Metab 1998; 83: 2777-2780. (Pubitemid 28493775)
16. Delgrange E, Trouillas J, Maiter D, Donckier J, Tourniaire J: Sex related difference in the growth of prolactinomas: a clinical and proliferation marker study. J Clin Endocrinol Metab 1997; 82: 2102-2107. (Pubitemid 27287568)
17. Duntas LH: Prolactinomas in children and adolescents: consequences in adult life. J Pediatr Endocrinol Metab 2001; 14: 1227-1232. (Pubitemid 33094788)
18. Noczynska A, Wasikowa R: Hyperprolactinaemia in children during the peripubertal period-personal observation. J Pediatr Endocrinol Metab 2004; 17: 1399-1404.
19. Casano P, Lopez Bermejo A, Valls Carme, Val A, Ibanez L: Heterogeneous presentation and outcome of prolactinomas in adolescence. Abstr 45th Ann Meet ESPE, Rotterdam, 2006. Horm Res 2006;65(suppl 4):187.
20. Kaplan SA: Growth and growth hormone: disorders of the anterior pituitary; in Kaplan SA (ed): Clinical Pediatric Endocrinology, ed 2. Philadelphia, Saunders, 1990, pp 1-62.
21. Popovic V, Simic M, Ilic Lj, Micic D, Damjanovic S, Djurovic M, Obradovic S, Dieguez C, Casanueva F: Growth hormone secretion elicited by GHRH, GHRP-6 or GHRH plus GHRP-6 in patients with microprolactinoma and macroprolactinoma before and after bromocriptine therapy. Clin Endocrinol 1998; 48: 103-108. (Pubitemid 28122440)
22. Duran P, Kramer RE: Pediatric obesity: Concerns and controversies. Pediatr Case Rev 2002; 2: 168-179.
23. Bellastella A, Bizzaro A, Coronella C, Bellastella G, Sinsi AA, de Bells A: Lymphocytic hypophysitis: a rare or underestimated disease. Eur J Endocrinol 2003; 149: 363-376. (Pubitemid 37461516)
24. Voorhess ML: Disorders of the adrenal medulla and multiple endocrine adenomatosis syndromes; in Kaplan SA (ed): Clinical Pediatric Endocrinology, ed 2. Philadelphia, Saunders, 1990, pp 235-258.
25. Lips CJM, Hopener JWM, van der Luijt RB: Introduction to multiple endocrine neoplasia syndromes. Top Endocrinol 2001; 18: 2-6.
26. Peracchi M, Conte D, Gebbia C, Penati C, Pizzinelli S, Arosio M, Corbeta S, Spada A: Plasma chromogranin A in patients with sporadic gastro-entero- pancreatic neuroenocrine tumors or multiple endocrine neoplasia type 1. Eur J Endocrinol 2003; 148: 39-43. (Pubitemid 36176003)
27. Geerdink EAM, Van der Luijt RB, Lips CJM: Do patients with multiple endocrine neoplasia syndrome type 1 benefit from periodical screening? Eur J Endocrinol 2003; 149: 577-582. (Pubitemid 38054703)
28. Saranac Lj, Stamenkovic H, Radovanovic Z, Kostic G, Bjelakovic B: Microprolactinoma: an unusual cause of growth hormone deficiency in a prepubertal obese boy. Int J Dis Hum Dev 2005; 4: 147-149. (Pubitemid 44783460)
29. Rosenfield RL: The ovary and female sexual maturation; in Kaplan SA (ed): Clinical Pediatric Endocrinology, ed 2. Philadelphia, Saunders, 1990, pp 259-323.