Weary of the stress: Time to put another notch in cardiomyopathy

Circulation Research

Volumn 106, Issue 7, 2010, Pages 1187-1189

  Morrisey, Edward E ^a  

^a UNIVERSITY OF PENNSYLVANIA   (United States)

Author keywords

[No Author keywords available]

Indexed keywords

NOTCH RECEPTOR; UNCLASSIFIED DRUG; WRY PROTEIN;

ANIMAL EXPERIMENT; ANIMAL MODEL; CARDIOMYOPATHY; DROSOPHILA; EDITORIAL; GENE FUNCTION; HEART DEVELOPMENT; HEART FAILURE; HEART MUSCLE CELL; NONHUMAN; PRIORITY JOURNAL; PROTEIN DETERMINATION; PROTEIN EXPRESSION; SIGNAL TRANSDUCTION; STRESS; TRANSCRIPTION REGULATION;

ANIMALS; CARDIOMYOPATHY, DILATED; CELL ADHESION; CELL AGGREGATION; DROSOPHILA MELANOGASTER; DROSOPHILA PROTEINS; GENE DELETION; GENOTYPE; HUMANS; LIGANDS; PHENOTYPE; RECEPTORS, NOTCH; RECOMBINANT PROTEINS; SIGNAL TRANSDUCTION; TOMOGRAPHY, OPTICAL COHERENCE; TRANSCRIPTIONAL ACTIVATION;

EID: 77951265004     PISSN: 00097330     EISSN: 15244571     Source Type: Journal    
DOI: 10.1161/CIRCRESAHA.110.218974     Document Type: Editorial

References (16)

1. Iso T, Kedes L, Hamamori Y. HES and HERP families: multiple effectors of the Notch signaling pathway. J Cell Physiol. 2003;194:237-255. (Pubitemid 36176887)
2. Niessen K, Karsan A. Notch signaling in cardiac development. Circ Res. 2008;102:1169-1181.
3. High FA, Epstein JA. The multifaceted role of Notch in cardiac development and disease. Nat Rev Genet. 2008;9:49-61.
4. High FA, Jain R, Stoller JZ, Antonucci NB, Lu MM, Loomes KM, Kaestner KH, Pear WS, Epstein JA. Murine Jagged1/Notch signaling in the second heart field orchestrates Fgf8 expression and tissue-tissue interactions during outflow tract development. J Clin Invest. 2009;119: 1986-1996.
5. High FA, Lu MM, Pear WS, Loomes KM, Kaestner KH, Epstein JA. Endothelial expression of the Notch ligand Jagged1 is required for vascular smooth muscle development. Proc Natl Acad Sci USA. 2008; 105:1955-1959.
6. High FA, Zhang M, Proweller A, Tu L, Parmacek MS, Pear WS, Epstein JA. An essential role for Notch in neural crest during cardiovascular development and smooth muscle differentiation. J Clin Invest. 2007;117: 353-363. (Pubitemid 46203964)
7. Grego-Bessa J, Luna-Zurita L, del Monte G, Bolos V, Melgar P, Arandilla A, Garratt AN, Zang H, Mukouyama YS, Chen H, Shou W, Ballestar E, Esteller M, Rojas A, Perez-Pomares JM, de la Pompa JL. Notch signaling is essential for ventricular chamber development. Dev Cell. 2007;12:415-429. (Pubitemid 46300059)
8. Timmerman LA, Grego-Bessa J, Raya A, Bertran E, Perez-Pomares JM, Diez J, Aranda S, Palomo S, McCormick F, Izpisua-Belmonte JC, de la Pompa JL. Notch promotes epithelial-mesenchymal transition during cardiac development and oncogenic transformation. Genes Dev. 2004;18: 99-115. (Pubitemid 38090691)
9. Chen VC, Stull R, Joo D, Cheng X, Keller G. Notch signaling respecifies the hemangioblast to a cardiac fate. Nat Biotechnol. 2008;26:1169-1178.
10. Nemir M, Croquelois A, Pedrazzini T, Radtke F. Induction of cardio-genesis in embryonic stem cells via downregulation of Notch1 signaling. Circ Res. 2006;98:1471-1478. (Pubitemid 44297069)
11. Hayward P, Kalmar T, Arias AM. Wnt/Notch signalling and information processing during development. Development. 2008;135:411-424.
12. Kim IL, Wolf MJ, Rockman HA. Gene deletion screen for cardiomyop-athy in adult Drosophila identifies a new Notch ligand. Circ Res. 2010; 106:1233-1243.
13. Hu QD, Ang BT, Karsak M, Hu WP, Cui XY, Duka T, Takeda Y, Chia W, Sankar N, Ng YK, Ling EA, Maciag T, Small D, Trifonova R, Kopan R, Okano H, Nakafuku M, Chiba S, Hirai H, Aster JC, Schachner M, Pallen CJ, Watanabe K, Xiao ZC. F3/contactin acts as a functional ligand for Notch during oligodendrocyte maturation. Cell. 2003;115:163-175. (Pubitemid 37329580)
14. Eiraku M, Tohgo A, Ono K, Kaneko M, Fujishima K, Hirano T, Kengaku M. DNER acts as a neuron-specific Notch ligand during Bergmann glial development. Nat Neurosci. 2005;8:873-880.
15. Croquelois A, Domenighetti AA, Nemir M, Lepore M, Rosenblatt-Velin N, Radtke F, Pedrazzini T. Control of the adaptive response of the heart to stress via the Notch1 receptor pathway. J Exp Med. 2008;205: 3173-3185.
16. Campa VM, Gutierrez-Lanza R, Cerignoli F, Diaz-Trelles R, Nelson B, Tsuji T, Barcova M, Jiang W, Mercola M. Notch activates cell cycle reentry and progression in quiescent cardiomyocytes. J Cell Biol. 2008;183:129-141.