Purification using the Multicolumn Countercurrent Solvent Gradient Purification (MCSGP) Process

BioPharm International

Volumn 22, Issue 1, 2009, Pages 46-52

  Aumann, Lars ^a   Stroehicin, Guido ^a   Mueller Spoeth, Thomas ^a   Morbidelli, Massimo ^b   Schenkel, Berthold ^c  

^a CHROMACON AG   (Switzerland)

^b ETH ZURICH   (Switzerland)

^c NOVARTIS PHARMA AG   (Switzerland)

Author keywords

[No Author keywords available]

Indexed keywords

CALCITONIN; MONOCLONAL ANTIBODY; POLYPEPTIDE;

BATCH PROCESS; DRUG INDUSTRY; DRUG PURIFICATION; DRUG PURITY; ELUTION; ENANTIOMER; HUMAN; REVERSED PHASE LIQUID CHROMATOGRAPHY; REVIEW; SEPARATION TECHNIQUE; SOLVENT EXTRACTION;

EID: 77951262767     PISSN: 1542166X     EISSN: None     Source Type: Journal    
DOI: None     Document Type: Review

References (16)

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2. Aumann L, Stroehlein G, Morbidelli M. Parametric study of a 6-column countercurrent solvent gradient purification (MCSGP) unit. Biotechnol Bioeng. 2001;98(5):1029-1042.
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4. Stroehlein G, Aumann L, Mueller-Spaeth T, Tarafder A, Morbidelli M. Continuous Processing-the multicolumn countercurrent solvent gradient purification process. Supplement to BioPharm mt. 2007 Feb. (Pubitemid 46281077)
5. Aumann L, Morbidelli M, inventors; ChromaCon AG, assignee. European patent, EP 05405321.7, EP 05405421.8, 2005.
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