A semicontinuous 3-column Countercurrent Solvent Gradient Purification (MCSGP) process

Biotechnology and Bioengineering

Volumn 99, Issue 3, 2008, Pages 728-733

  Aumann, Lars ^a   Morbidelli, Massimo ^a  

^a ETH ZURICH   (Switzerland)

Author keywords

Biochromatography; Calcitonin; Countercurrent solvent gradient; MCSGP; Peptide purification; Semi continuous; SMB; Three fraction separation

Indexed keywords

COLUMN CHROMATOGRAPHY; PURIFICATION; SEPARATION; SOLVENTS;

BIOCHROMATOGRAPHY; CALCITONIN; COUNTERCURRENT SOLVENT GRADIENT; PEPTIDE PURIFICATION; THREE FRACTION SEPARATION;

PEPTIDES;

CALCITONIN; RESIN; SOLVENT;

ARTICLE; COLUMN CHROMATOGRAPHY; MULTICOLUMN COUNTERCURRENT SOLVENT GRADIENT PURIFICATION; PROCESSING; PROTEIN PURIFICATION; SEPARATION TECHNIQUE; SIMULATION; CHEMICAL MODEL; CHEMISTRY; COMPUTER AIDED DESIGN; COMPUTER SIMULATION; EQUIPMENT; EQUIPMENT DESIGN; HIGH PERFORMANCE LIQUID CHROMATOGRAPHY; INSTRUMENTATION; METHODOLOGY;

CHROMATOGRAPHY, HIGH PRESSURE LIQUID; COMPUTER SIMULATION; COMPUTER-AIDED DESIGN; EQUIPMENT DESIGN; EQUIPMENT FAILURE ANALYSIS; MODELS, CHEMICAL; SOLVENTS;

EID: 38449108857     PISSN: 00063592     EISSN: 10970290     Source Type: Journal    
DOI: 10.1002/bit.21585     Document Type: Article

References (3)

1. Aumann L, Morbidelli M. 2005. European Patent, Patent No: 05405421.8.
2. Aumann L, Morbidelli M. 2007. A Continuous Multicolumn Countercurrent Solvent Gradient Purification (MCSGP) Process. Journal of Biotechnology and Bioengineering (in press).
3. Aumann L, Stroehlein G, Morbidelli M. 2007. Parametric Study of a 6-column Countercurrent Solvent Gradient Purification Unit. Journal of Biotechnology and Bioengineering (in press).