p90 ribosomal S6 kinase 1 (RSK1) and the catalytic subunit of protein kinase a (PKA) compete for binding the pseudosubstrate region of PKAR1α: Role in the regulation of PKA and RSK1 activities

Journal of Biological Chemistry

Volumn 285, Issue 10, 2010, Pages 6970-6979

  Gao, Xianlong ^a   Chaturvedi, Deepti ^a   Patel, Tarun B ^a  

^a LOYOLA UNIVERSITY CHICAGO   (United States)

Author keywords

[No Author keywords available]

Indexed keywords

ACTIVATION LOOPS; APOPTOSIS; ARG RESIDUES; BIOLOGICAL FUNCTIONS; CATALYTIC SUBUNITS; GROWTH FACTOR; IN-VITRO; INTACT CELLS; KINASE DOMAINS; N-TERMINALS; P90 RIBOSOMAL S6 KINASE; PHOSPHORYLATION SITES; PROTEIN KINASE A; REGULATORY SUBUNITS;

AMINO ACIDS; CELL DEATH; FETAL MONITORING; LAWS AND LEGISLATION; ORGANIC ACIDS; PEPTIDES; PHOSPHORYLATION;

ASSOCIATION REACTIONS;

ASPARTIC ACID; CYCLIC AMP DEPENDENT PROTEIN KINASE; CYCLIC AMP DEPENDENT PROTEIN KINASE REGULATORY SUBUNIT IALPHA; P90 RIBOSOMAL S6 KINASE 1; S6 KINASE; SERINE; UNCLASSIFIED DRUG;

AMINO ACID SUBSTITUTION; AMINO TERMINAL SEQUENCE; ANIMAL CELL; ARTICLE; BINDING AFFINITY; CARBOXY TERMINAL SEQUENCE; CONTROLLED STUDY; ENZYME ACTIVATION; ENZYME ACTIVITY; ENZYME BINDING; ENZYME PHOSPHORYLATION; ENZYME SUBSTRATE; GENE OVEREXPRESSION; GENE SILENCING; HUMAN; HUMAN CELL; IN VITRO STUDY; MOUSE; NONHUMAN; PRIORITY JOURNAL; PROMOTER REGION; PROTEIN PROTEIN INTERACTION;

ANIMALS; BINDING SITES; CATALYTIC DOMAIN; CELL LINE; CYCLIC AMP; CYCLIC AMP-DEPENDENT PROTEIN KINASE RIALPHA SUBUNIT; CYCLIC AMP-DEPENDENT PROTEIN KINASES; HUMANS; ISOENZYMES; MICE; PROTEIN BINDING; RATS; RECOMBINANT FUSION PROTEINS; RIBOSOMAL PROTEIN S6 KINASES, 90-KDA; RNA, SMALL INTERFERING;

EID: 77951251394     PISSN: 00219258     EISSN: 1083351X     Source Type: Journal    
DOI: 10.1074/jbc.M109.083642     Document Type: Article

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