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Volumn 51, Issue 4, 2010, Pages 1927-1934

Disruption of mouse corneal epithelial differentiation cby conditional inactivation of Pnn

Author keywords

[No Author keywords available]

Indexed keywords

BETA CATENIN; CYCLIN D1; CYTOKERATIN 10; CYTOKERATIN 12; CYTOKERATIN 14; KI 67 ANTIGEN; PHOSPHOPROTEIN; PININ; PROTEIN P68; RNA HELICASE; TRANSCRIPTION FACTOR; TRANSCRIPTION FACTOR 4; TRANSCRIPTION FACTOR PAX6; UNCLASSIFIED DRUG; BASIC HELIX LOOP HELIX LEUCINE ZIPPER TRANSCRIPTION FACTOR; CATNB PROTEIN, MOUSE; CELL ADHESION MOLECULE; CRE RECOMBINASE; DEAD BOX PROTEIN; EYE PROTEIN; GREEN FLUORESCENT PROTEIN; HOMEODOMAIN PROTEIN; INTEGRASE; KERATIN; NUCLEAR PROTEIN; PAIRED BOX TRANSCRIPTION FACTOR; PNN PROTEIN, MOUSE; REPRESSOR PROTEIN; TCF4 PROTEIN, MOUSE;

EID: 77951250927     PISSN: 01460404     EISSN: 15525783     Source Type: Journal    
DOI: 10.1167/iovs.09-4591     Document Type: Article
Times cited : (27)

References (45)
  • 1
    • 0000638543 scopus 로고
    • The cell biology of the corneal epithelium
    • In: Albert DM, Jakobiec FA, eds., Philadelphia: W.B. Saunders Company
    • Gipson IK, Sugrue SP. The cell biology of the corneal epithelium. In: Albert DM, Jakobiec FA, eds. Principles and Practices of Ophthalmology. Philadelphia: W.B. Saunders Company; 1994:3-16.
    • (1994) Principles and Practices of Ophthalmology , pp. 3-16
    • Gipson, I.K.1    Sugrue, S.P.2
  • 2
    • 35348996450 scopus 로고    scopus 로고
    • Genetic and epigenetic mechanisms of gene regulation during lens development
    • Cvekl A, Duncan MK. Genetic and epigenetic mechanisms of gene regulation during lens development. Prog Retin Eye Res. 2007;26: 555-597.
    • (2007) Prog Retin Eye Res , vol.26 , pp. 555-597
    • Cvekl, A.1    Duncan, M.K.2
  • 3
    • 1842714360 scopus 로고    scopus 로고
    • Anterior eye development and ocular mesenchyme: New insights from mouse models and human diseases
    • Cvekl A, Tamm ER. Anterior eye development and ocular mesenchyme: new insights from mouse models and human diseases. Bioessays. 2004;26:374-386.
    • (2004) Bioessays , vol.26 , pp. 374-386
    • Cvekl, A.1    Tamm, E.R.2
  • 4
    • 34548097333 scopus 로고    scopus 로고
    • The requirement of pax6 for postnatal eye development: Evidence from experimental mouse chimeras
    • Li S, Goldowitz D, Swanson DJ. The requirement of pax6 for postnatal eye development: evidence from experimental mouse chimeras. Invest Ophthalmol Vis Sci. 2007;48:3292-3300.
    • (2007) Invest Ophthalmol Vis Sci , vol.48 , pp. 3292-3300
    • Li, S.1    Goldowitz, D.2    Swanson, D.J.3
  • 5
    • 0035545995 scopus 로고    scopus 로고
    • Pax6 lights-up the way for eye development
    • Ashery-Padan R, Gruss P. Pax6 lights-up the way for eye development. Curr Opin Cell Biol. 2001;13:706-714.
    • (2001) Curr Opin Cell Biol , vol.13 , pp. 706-714
    • Ashery-Padan, R.1    Gruss, P.2
  • 6
    • 0036805779 scopus 로고    scopus 로고
    • Pax6 heterozygous eyes show defects in chamber angle differentiation that are associated with a wide spectrum of other anterior eye segment abnormalities
    • Baulmann DC, Ohlmann A, Flügel-Koch C, Goswami S, Cvekl A, Tamm ER. Pax6 heterozygous eyes show defects in chamber angle differentiation that are associated with a wide spectrum of other anterior eye segment abnormalities. Mech Dev. 2002;118:3-17.
    • (2002) Mech Dev , vol.118 , pp. 3-17
    • Baulmann, D.C.1    Ohlmann, A.2    Flügel-Koch, C.3    Goswami, S.4    Cvekl, A.5    Tamm, E.R.6
  • 7
    • 0030790020 scopus 로고    scopus 로고
    • Current views on eye development
    • Oliver G, Gruss P. Current views on eye development. Trends Neurosci. 1997;20:415-421.
    • (1997) Trends Neurosci , vol.20 , pp. 415-421
    • Oliver, G.1    Gruss, P.2
  • 9
    • 4544247202 scopus 로고    scopus 로고
    • How to make an eye
    • Treisman JE. How to make an eye. Development. 2004;131:3823-3827.
    • (2004) Development , vol.131 , pp. 3823-3827
    • Treisman, J.E.1
  • 11
    • 57649217598 scopus 로고    scopus 로고
    • Homeodomain protein Pitx3 maintains the mitotic activity of lens epithelial cells
    • Ho HY, Chang KH, Nichols J, Li M. Homeodomain protein Pitx3 maintains the mitotic activity of lens epithelial cells. Mech Dev. 2009;126:18-29.
    • (2009) Mech Dev , vol.126 , pp. 18-29
    • Ho, H.Y.1    Chang, K.H.2    Nichols, J.3    Li, M.4
  • 12
    • 39549090013 scopus 로고    scopus 로고
    • Air exposure induced squamous metaplasia of human limbal epithelium
    • Li W, Hayashida Y, Chen YT, et al. Air exposure induced squamous metaplasia of human limbal epithelium. Invest Ophthalmol Vis Sci. 2008;49:154-162.
    • (2008) Invest Ophthalmol Vis Sci , vol.49 , pp. 154-162
    • Li, W.1    Hayashida, Y.2    Chen, Y.T.3
  • 13
    • 70349116543 scopus 로고    scopus 로고
    • Targeted deletion of Dicer disrupts lens morphogenesis, corneal epithelium stratification, and whole eye development
    • Li Y, Piatigorsky J. Targeted deletion of Dicer disrupts lens morphogenesis, corneal epithelium stratification, and whole eye development. Dev Dyn. 2009;238:2388-2400.
    • (2009) Dev Dyn , vol.238 , pp. 2388-2400
    • Li, Y.1    Piatigorsky, J.2
  • 14
    • 40849094420 scopus 로고    scopus 로고
    • Cell autonomous roles for AP-2alpha in lens vesicle separation and maintenance of the lens epithelial cell phenotype
    • Pontoriero GF, Deschamps P, Ashery-Padan R, et al. Cell autonomous roles for AP-2alpha in lens vesicle separation and maintenance of the lens epithelial cell phenotype. Dev Dyn. 2008;237: 602-617.
    • (2008) Dev Dyn , vol.237 , pp. 602-617
    • Pontoriero, G.F.1    Deschamps, P.2    Ashery-Padan, R.3
  • 15
    • 27744542002 scopus 로고    scopus 로고
    • Regulation of ocular lens development by Smad-interacting protein 1 involving Foxe3 activation
    • Yoshimoto A, Saigou Y, Higashi Y, Kondoh H. Regulation of ocular lens development by Smad-interacting protein 1 involving Foxe3 activation. Development. 2005;132:4437-4448.
    • (2005) Development , vol.132 , pp. 4437-4448
    • Yoshimoto, A.1    Saigou, Y.2    Higashi, Y.3    Kondoh, H.4
  • 16
    • 8644237368 scopus 로고    scopus 로고
    • Nuclear speckle-associated protein Pnn/DRS binds to the transcriptional corepressor CtBP and relieves CtBP-mediated repression of the E-cadherin gene
    • Alpatov R, Munguba GC, Caton P, et al. Nuclear speckle-associated protein Pnn/DRS binds to the transcriptional corepressor CtBP and relieves CtBP-mediated repression of the E-cadherin gene. Mol Cell Biol. 2004;24:10223-10235.
    • (2004) Mol Cell Biol , vol.24 , pp. 10223-10235
    • Alpatov, R.1    Munguba, G.C.2    Caton, P.3
  • 17
    • 40749155486 scopus 로고    scopus 로고
    • Corepressor CtBP and nuclear speckle protein Pnn/DRS differentially modulate transcription and splicing of the E-cadherin gene
    • Alpatov R, Shi Y, Munguba GC, et al. Corepressor CtBP and nuclear speckle protein Pnn/DRS differentially modulate transcription and splicing of the E-cadherin gene. Mol Cell Biol. 2008;28:1584-1595.
    • (2008) Mol Cell Biol , vol.28 , pp. 1584-1595
    • Alpatov, R.1    Shi, Y.2    Munguba, G.C.3
  • 18
    • 25444489054 scopus 로고    scopus 로고
    • Reduction of Pnn by RNAi induces loss of cell-cell adhesion between human corneal epithelial cells
    • Joo JH, Alpatov R, Munguba GC, Jackson MR, Hunt ME, Sugrue SP. Reduction of Pnn by RNAi induces loss of cell-cell adhesion between human corneal epithelial cells. Mol Vis. 2005;11:133-142.
    • (2005) Mol Vis , vol.11 , pp. 133-142
    • Joo, J.H.1    Alpatov, R.2    Munguba, G.C.3    Jackson, M.R.4    Hunt, M.E.5    Sugrue, S.P.6
  • 19
    • 34548082793 scopus 로고    scopus 로고
    • Role of Pinin in neural crest, dorsal dermis, and axial skeleton development and its involvement in the regulation of Tcf/Lef activity in mice
    • Joo JH, Lee YJ, Munguba GC, et al. Role of Pinin in neural crest, dorsal dermis, and axial skeleton development and its involvement in the regulation of Tcf/Lef activity in mice. Dev Dyn. 2007;236: 2147-2158.
    • (2007) Dev Dyn , vol.236 , pp. 2147-2158
    • Joo, J.H.1    Lee, Y.J.2    Munguba, G.C.3
  • 20
    • 0026709315 scopus 로고
    • Identification of an epithelial protein related to the desmosome and intermediate filament network
    • Ouyang P, Sugrue SP. Identification of an epithelial protein related to the desmosome and intermediate filament network. J Cell Biol. 1992;118:1477-1488.
    • (1992) J Cell Biol , vol.118 , pp. 1477-1488
    • Ouyang, P.1    Sugrue, S.P.2
  • 21
    • 0029836931 scopus 로고    scopus 로고
    • Characterization of pinin, a novel protein associated with the desmosome-intermediate filament complex
    • Ouyang P, Sugrue SP. Characterization of pinin, a novel protein associated with the desmosome-intermediate filament complex. J Cell Biol. 1996;135:1027-1042.
    • (1996) J Cell Biol , vol.135 , pp. 1027-1042
    • Ouyang, P.1    Sugrue, S.P.2
  • 22
    • 0034685789 scopus 로고    scopus 로고
    • Dissection of protein linkage between keratins and pinin, a protein with dual location at desmosome-intermediate filament complex and in the nucleus
    • Shi J, Sugrue SP. Dissection of protein linkage between keratins and pinin, a protein with dual location at desmosome-intermediate filament complex and in the nucleus. J Biol Chem. 2000;275: 14910-14915.
    • (2000) J Biol Chem , vol.275 , pp. 14910-14915
    • Shi, J.1    Sugrue, S.P.2
  • 23
    • 0034642508 scopus 로고    scopus 로고
    • Characterization of the gene encoding pinin/DRS/memA and evidence for its potential tumor suppressor function
    • Shi Y, Ouyang P, Sugrue SP. Characterization of the gene encoding pinin/DRS/memA and evidence for its potential tumor suppressor function. Oncogene. 2000;19:289-297.
    • (2000) Oncogene , vol.19 , pp. 289-297
    • Shi, Y.1    Ouyang, P.2    Sugrue, S.P.3
  • 24
    • 0035811592 scopus 로고    scopus 로고
    • Change in gene expression subsequent to induction of Pnn/DRS/memA: Increase in p21(cip1/waf1)
    • Shi Y, Simmons MN, Seki T, Oh SP, Sugrue SP. Change in gene expression subsequent to induction of Pnn/DRS/memA: increase in p21(cip1/waf1). Oncogene. 2001;20:4007-4018.
    • (2001) Oncogene , vol.20 , pp. 4007-4018
    • Shi, Y.1    Simmons, M.N.2    Seki, T.3    Oh, S.P.4    Sugrue, S.P.5
  • 25
    • 0034015022 scopus 로고    scopus 로고
    • Role of cell adhesion-associated protein, pinin (DRS/memA), in corneal epithelial migration
    • Shi Y, Tabesh M, Sugrue SP. Role of cell adhesion-associated protein, pinin (DRS/memA), in corneal epithelial migration. Invest Ophthalmol Vis Sci. 2000;41:1337-1345.
    • (2000) Invest Ophthalmol Vis Sci , vol.41 , pp. 1337-1345
    • Shi, Y.1    Tabesh, M.2    Sugrue, S.P.3
  • 26
    • 0142200849 scopus 로고    scopus 로고
    • Pinin/DRS/memA interacts with SRp75, SRm300 and SRrp130 in corneal epithelial cells
    • Zimowska G, Shi J, Munguba GC, et al. Pinin/DRS/memA interacts with SRp75, SRm300 and SRrp130 in corneal epithelial cells. Invest Ophthalmol Vis Sci. 2003;44:4715-4723.
    • (2003) Invest Ophthalmol Vis Sci , vol.44 , pp. 4715-4723
    • Zimowska, G.1    Shi, J.2    Munguba, G.C.3
  • 27
    • 0034312313 scopus 로고    scopus 로고
    • Pax6 activity in the lens primordium is required for lens formation and for correct placement of a single retina in the eye
    • Ashery-Padan R, Marquardt T, Zhou X, Gruss P. Pax6 activity in the lens primordium is required for lens formation and for correct placement of a single retina in the eye. Genes Dev. 2000;14:2701-2711.
    • (2000) Genes Dev , vol.14 , pp. 2701-2711
    • Ashery-Padan, R.1    Marquardt, T.2    Zhou, X.3    Gruss, P.4
  • 28
    • 0032923739 scopus 로고    scopus 로고
    • Generalized lacZ expression with the ROSA26 Cre reporter strain
    • Soriano P. Generalized lacZ expression with the ROSA26 Cre reporter strain. Nat Genet. 1999;21:70-71.
    • (1999) Nat Genet , vol.21 , pp. 70-71
    • Soriano, P.1
  • 29
    • 0037166326 scopus 로고    scopus 로고
    • Aquaporin deletion in mice reduces corneal water permeability and delays restoration of transparency after swelling
    • Thiagarajah JR, Verkman AS. Aquaporin deletion in mice reduces corneal water permeability and delays restoration of transparency after swelling. J Biol Chem. 2002;277:19139-19144.
    • (2002) J Biol Chem , vol.277 , pp. 19139-19144
    • Thiagarajah, J.R.1    Verkman, A.S.2
  • 30
    • 33644859358 scopus 로고    scopus 로고
    • Expression of keratin 12 and maturation of corneal epithelium during development and postnatal growth
    • Tanifuji-Terai N, Terai K, Hayashi Y, Chikama T, Kao WW. Expression of keratin 12 and maturation of corneal epithelium during development and postnatal growth. Invest Ophthalmol Vis Sci. 2006;47:545-551.
    • (2006) Invest Ophthalmol Vis Sci , vol.47 , pp. 545-551
    • Tanifuji-Terai, N.1    Terai, K.2    Hayashi, Y.3    Chikama, T.4    Kao, W.W.5
  • 31
    • 38049018919 scopus 로고    scopus 로고
    • Down-regulation of Pax6 is associated with abnormal differentiation of corneal epithelial cells in severe ocular surface diseases
    • Li W, Chen YT, Hayashida Y, et al. Down-regulation of Pax6 is associated with abnormal differentiation of corneal epithelial cells in severe ocular surface diseases. J Pathol. 2008;214:114-122.
    • (2008) J Pathol , vol.214 , pp. 114-122
    • Li, W.1    Chen, Y.T.2    Hayashida, Y.3
  • 32
    • 33749078750 scopus 로고    scopus 로고
    • P68 R.N.A.helicase mediates PDGF-induced epithelial mesenchymal transition by displacing Axin from betacatenin
    • Yang L, Lin C, Liu ZR. P68 RNA helicase mediates PDGF-induced epithelial mesenchymal transition by displacing Axin from betacatenin. Cell. 2006;127:139-155.
    • (2006) Cell , vol.127 , pp. 139-155
    • Yang, L.1    Lin, C.2    Liu, Z.R.3
  • 33
    • 25844490866 scopus 로고    scopus 로고
    • The duality of beta-catenin function: A requirement in lens morphogenesis and signaling suppression of lens fate in periocular ectoderm
    • Smith AN, Miller LA, Song N, Taketo MM, Lang RA. The duality of beta-catenin function: a requirement in lens morphogenesis and signaling suppression of lens fate in periocular ectoderm. Dev Biol 2005;285:477-489.
    • (2005) Dev Biol , vol.285 , pp. 477-489
    • Smith, A.N.1    Miller, L.A.2    Song, N.3    Taketo, M.M.4    Lang, R.A.5
  • 34
    • 25844524620 scopus 로고    scopus 로고
    • Canonical Wnt signaling negatively regulates branching morphogenesis of the lung and lacrimal gland
    • Dean CH, Miller LA, Smith AN, Dufort D, Lang RA, Niswander LA. Canonical Wnt signaling negatively regulates branching morphogenesis of the lung and lacrimal gland. Dev Biol. 2005;286:270-286.
    • (2005) Dev Biol , vol.286 , pp. 270-286
    • Dean, C.H.1    Miller, L.A.2    Smith, A.N.3    Dufort, D.4    Lang, R.A.5    Niswander, L.A.6
  • 35
    • 42649083977 scopus 로고    scopus 로고
    • The canonical Wnt signaling antagonist DKK2 is an essential effector of PITX2 function during normal eye development
    • Gage PJ, Qian M, Wu D, Rosenberg KI. The canonical Wnt signaling antagonist DKK2 is an essential effector of PITX2 function during normal eye development. Dev Biol. 2008;317:310-324.
    • (2008) Dev Biol , vol.317 , pp. 310-324
    • Gage, P.J.1    Qian, M.2    Wu, D.3    Rosenberg, K.I.4
  • 36
    • 33745618132 scopus 로고    scopus 로고
    • Dkk2 plays an essential role in the corneal fate of the ocular surface epithelium
    • Mukhopadhyay M, Gorivodsky M, Shtrom S, et al. Dkk2 plays an essential role in the corneal fate of the ocular surface epithelium. Development. 2006;133:2149-2154.
    • (2006) Development , vol.133 , pp. 2149-2154
    • Mukhopadhyay, M.1    Gorivodsky, M.2    Shtrom, S.3
  • 37
    • 3042582129 scopus 로고    scopus 로고
    • Transdifferentiation of corneal epithelium: Evidence for a linkage between the segregation of epidermal stem cells and the induction of hair follicles during embryogenesis
    • Pearton DJ, Ferraris C, Dhouailly D. Transdifferentiation of corneal epithelium: evidence for a linkage between the segregation of epidermal stem cells and the induction of hair follicles during embryogenesis. Int J Dev Biol. 2004;48:197-201.
    • (2004) Int J Dev Biol , vol.48 , pp. 197-201
    • Pearton, D.J.1    Ferraris, C.2    Dhouailly, D.3
  • 38
    • 14844343588 scopus 로고    scopus 로고
    • Transdifferentiation of corneal epithelium into epidermis occurs by means of a multistep process triggered by dermal developmental signals
    • Pearton DJ, Yang Y, Dhouailly D. Transdifferentiation of corneal epithelium into epidermis occurs by means of a multistep process triggered by dermal developmental signals. Proc Natl Acad Sci U S A. 2005;102:3714-3719.
    • (2005) Proc Natl Acad Sci U S A , vol.102 , pp. 3714-3719
    • Pearton, D.J.1    Yang, Y.2    Dhouailly, D.3
  • 39
    • 18844446130 scopus 로고    scopus 로고
    • RNA helicases: Regulators of differentiation
    • Abdelhaleem M. RNA helicases: regulators of differentiation. Clin Biochem. 2005;38:499-503.
    • (2005) Clin Biochem , vol.38 , pp. 499-503
    • Abdelhaleem, M.1
  • 40
    • 54249167990 scopus 로고    scopus 로고
    • The RNA helicase p68 is a novel androgen receptor coactivator involved in splicing and is overexpressed in prostate cancer
    • Clark EL, Coulson A, Dalgliesh C, et al. The RNA helicase p68 is a novel androgen receptor coactivator involved in splicing and is overexpressed in prostate cancer. Cancer Res. 2008;68:7938-7946.
    • (2008) Cancer Res , vol.68 , pp. 7938-7946
    • Clark, E.L.1    Coulson, A.2    Dalgliesh, C.3
  • 41
    • 49349104315 scopus 로고    scopus 로고
    • The DEAD box RNA helicases p68 (Ddx5) and p72 (Ddx17): Novel transcriptional co-regulators
    • Fuller-Pace FV, Ali S. The DEAD box RNA helicases p68 (Ddx5) and p72 (Ddx17): novel transcriptional co-regulators. Biochem Soc Trans. 2008;36:609-612.
    • (2008) Biochem Soc Trans , vol.36 , pp. 609-612
    • Fuller-Pace, F.V.1    Ali, S.2
  • 42
    • 7244258951 scopus 로고    scopus 로고
    • P68 DEAD box R.N.A.helicase expression in keratinocytes Regulation, nucleolar localization, and functional connection to proliferation and vascular endothelial growth factor gene expression
    • Kahlina K, Goren I, Pfeilschifter J, Frank S. p68 DEAD box RNA helicase expression in keratinocytes. Regulation, nucleolar localization, and functional connection to proliferation and vascular endothelial growth factor gene expression. J Biol Chem. 2004;279: 44872-44882.
    • (2004) J Biol Chem , vol.279 , pp. 44872-44882
    • Kahlina, K.1    Goren, I.2    Pfeilschifter, J.3    Frank, S.4
  • 43
    • 38149129431 scopus 로고    scopus 로고
    • Identification of novel pathway partners of p68 and p72 RNA helicases through Oncomine meta-analysis
    • Wilson BJ, Gigue're V. Identification of novel pathway partners of p68 and p72 RNA helicases through Oncomine meta-analysis. BMC Genomics. 2007;8:419.
    • (2007) BMC Genomics , vol.8 , pp. 419
    • Wilson, B.J.1    Gigue're, V.2
  • 44
    • 21344459251 scopus 로고    scopus 로고
    • Phosphorylations of DEAD box p68 RNA helicase are associated with cancer development and cell proliferation
    • Yang L, Lin C, Liu ZR. Phosphorylations of DEAD box p68 RNA helicase are associated with cancer development and cell proliferation. Mol Cancer Res. 2005;3:355-363.
    • (2005) Mol Cancer Res , vol.3 , pp. 355-363
    • Yang, L.1    Lin, C.2    Liu, Z.R.3
  • 45
    • 41749105770 scopus 로고    scopus 로고
    • P68 (Ddx5) interacts with Runx2 and regulates osteoblast differentiation
    • Jensen ED, Niu L, Caretti G, et al. p68 (Ddx5) interacts with Runx2 and regulates osteoblast differentiation. J Cell Biochem. 2008;103: 1438-1451.
    • (2008) J Cell Biochem , vol.103 , pp. 1438-1451
    • Jensen, E.D.1    Niu, L.2    Caretti, G.3    et al4


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