Cutaneous model of invasive aspergillosis

Antimicrobial Agents and Chemotherapy

Volumn 54, Issue 5, 2010, Pages 1848-1854

  Ben Ami, Ronen ^a   Lewis, Russell E ^b   Leventakos, Konstantinos ^a   Latgé, Jean Paul ^c   Kontoyiannis, Dimitrios P ^a,b  

^a UNIVERSITY OF TEXAS   (United States)

^b UNIVERSITY OF HOUSTON   (United States)

^c INSTITUT PASTEUR   (France)

Author keywords

[No Author keywords available]

Indexed keywords

CATALASE; CYCLOPHOSPHAMIDE; FLUCONAZOLE; POSACONAZOLE;

ANIMAL EXPERIMENT; ANIMAL MODEL; ANIMAL TISSUE; ARTICLE; ASPERGILLOSIS; ASPERGILLUS FUMIGATUS; CONIDIUM; CONTROLLED STUDY; CUTANEOUS INVASIVE ASPERGILLOSIS; FEMALE; FUNGAL VIRULENCE; GENE DELETION; MOUSE; MYCELIUM; NONHUMAN; PRIORITY JOURNAL; SKIN DEFECT; SKIN INFECTION; TISSUE SPECIFICITY; VIRUS GENE;

ANIMALS; ANTIFUNGAL AGENTS; ASPERGILLOSIS; ASPERGILLUS FUMIGATUS; CATALASE; CYCLOPHOSPHAMIDE; DERMATOMYCOSES; DISEASE MODELS, ANIMAL; FEMALE; HYPHAE; IMMUNOCOMPROMISED HOST; IMMUNOSUPPRESSIVE AGENTS; MANNANS; MICE; MICE, INBRED BALB C; MICE, NUDE; MUTAGENESIS; SKIN; SPORES; TRIAZOLES; VIRULENCE; VIRULENCE FACTORS;

EID: 77951248796     PISSN: 00664804     EISSN: 10986596     Source Type: Journal    
DOI: 10.1128/AAC.01504-09     Document Type: Article

References (28)

1. Andriole, V. T., P. Miniter, D. George, D. Kordick, and T. F. Patterson. 1992. Animal models: usefulness for studies of fungal pathogenesis and drug efficacy in aspergillosis. Clin. Infect. Dis. 14(Suppl. 1):S134-S138.
2. Bélec, L., J. Authier, M. C. Eliezer-Vanerot, C. Piedouillet, A. S. Mohamed, and R. K. Gherardi. 1998. Myoglobin as a polymerase chain reaction (PCR) inhibitor: a limitation for PCR from skeletal muscle tissue avoided by the use of Thermus thermophilus polymerase. Muscle Nerve 21:1064-1067.
3. Ben-Ami, R., R. E. Lewis, K. Leventakos, and D. P. Kontoyiannis. 2009. Aspergillus fumigatus inhibits angiogenesis through the production of gliotoxin and other secondary metabolites. Blood 114:5393-5399.
4. Ben-Ami, R., R. E. Lewis, K. Leventakos, and D. P. Kontoyiannis. 2008. A murine model of myocutaneous invasive aspergillosis, abstr. M-1548. Abstr. 48th Intersci. Conf. Antimicrob. Agents Chemother. (ICAAC)-Infect. Dis. Soc. Am. (ISDA) 46th Annu. Meet. American Society for Microbiology and Infectious Diseases Society of America, Washington, DC.
5. Berenguer, J., M. C. Allende, J. W. Lee, K. Garrett, C. Lyman, N. M. Ali, J. Bacher, P. A. Pizzo, and T. J. Walsh. 1995. Pathogenesis of pulmonary aspergillosis. Granulocytopenia versus cyclosporine and methylprednisolone- induced immunosuppression. Am. J. Respir. Crit. Care Med. 152:1079-1086.
6. Bowman, J. C., G. K. Abruzzo, J. W. Anderson, A. M. Flattery, C. J. Gill, V. B. Pikounis, D. M. Schmatz, P. A. Liberator, and C. M. Douglas. 2001. Quantitative PCR assay to measure Aspergillus fumigatus burden in a murine model of disseminated aspergillosis: demonstration of efficacy of caspofungin acetate. Antimicrob. Agents Chemother. 45:3474-3481.
7. Brown, J. S., A. Aufauvre-Brown, J. Brown, J. M. Jennings, H. Arst, Jr., and D. W. Holden. 2000. Signature-tagged and directed mutagenesis identify PABA synthetase as essential for Aspergillus fumigatus pathogenicity. Mol. Microbiol. 36:1371-1380.
8. Bunce, C., L. Wheeler, G. Reed, J. Musser, and N. Barg. 1992. Murine model of cutaneous infection with gram-positive cocci. Infect. Immun. 60:2636-2640.
9. Burgos, A., T. E. Zaoutis, C. C. Dvorak, J. A. Hoffman, K. M. Knapp, J. J. Nania, P. Prasad, and W. J. Steinbach. 2008. Pediatric invasive aspergillosis: a multicenter retrospective analysis of 139 contemporary cases. Pediatrics 121:e1286-e1294.
10. Craig, W. A. 1998. Pharmacokinetic/pharmacodynamic parameters: rationale for antibacterial dosing of mice and men. Clin. Infect. Dis. 26:1-10.
11. Latgé, J.-P. 1999. Aspergillus fumigatus and aspergillosis. Clin. Microbiol. Rev. 12:310-350.
12. Lewis, R. E., and N. P. Wiederhold. 2005. Murine model of invasive aspergillosis. Methods Mol. Med. 118:129-142.
13. Monod, M., S. Paris, J. Sarfati, K. Jaton-Ogay, P. Ave, and J.-P. Latgé. 1993. Virulence of alkaline protease-deficient mutants of Aspergillus fumigatus. FEMS Microbiol. Lett. 106:39-46.
14. Nierman, W. C., A. Pain, M. J. Anderson, J. R. Wortman, H. S. Kim, J. Arroyo, M. Berriman, K. Abe, D. B. Archer, C. Bermejo, J. Bennett, P. Bowyer, D. Chen, M. Collins, R. Coulsen, R. Davies, P. S. Dyer, M. Farman, N. Fedorova, N. Fedorova, T. V. Feldblyum, R. Fischer, N. Fosker, A. Fraser, J. L. Garcia, M. J. Garcia, A. Goble, G. H. Goldman, K. Gomi, S. Griffith-Jones, R. Gwilliam, B. Haas, H. Haas, D. Harris, H. Horiuchi, J. Huang, S. Humphray, J. Jimenez, N. Keller, H. Khouri, K. Kitamoto, T. Kobayashi, S. Konzack, R. Kulkarni, T. Kumagai, A. Lafon, J.-P. Latgé, W. Li, A. Lord, C. Lu, W. H. Majoros, G. S. May, B. L. Miller, Y. Mohamoud, M. Molina, M. Monod, I. Mouyna, S. Mulligan, L. Murphy, S. O'Neil, I. Paulsen, M. A. Penalva, M. Pertea, C. Price, B. L. Pritchard, M. A. Quail, E. Rabbinowitsch, N. Rawlins, M. A. Rajandream, U. Reichard, H. Renauld, G. D. Robson, S. Rodriguez de Cordoba, J. M. Rodriguez-Pena, C. M. Ronning, S. Rutter, S. L. Salzberg, M. Sanchez, J. C. Sanchez-Ferrero, D. Saunders, K. Seeger, R. Squares, S. Squares, M. Takeuchi, F. Tekaia, G. Turner, C. R. Vazquez de Aldana, J. Weidman, O. White, J. Woodward, J. H. Yu, C. Fraser, J. E. Galagan, K. Asai, M. Machida, N. Hall, B. Barrell, and D. W. Denning. 2005. Genomic sequence of the pathogenic and allergenic filamentous fungus Aspergillus fumigatus. Nature 438:1151-1156.
15. Panackal, A. A., A. Imhof, E. W. Hanley, and K. A. Marr. 2006. Aspergillus ustus infections among transplant recipients. Emerg. Infect. Dis. 12:403-408.
16. Paris, S., D. Wysong, J.-P. Debeaupuis, K. Shibuya, B. Philippe, R. D. Diamond, and J.-P. Latgé. 2003. Catalases of Aspergillus fumigatus. Infect. Immun. 71:3551-3562.
17. Pasqualotto, A. C. 2009. Differences in pathogenicity and clinical syndromes due to Aspergillus fumigatus and Aspergillus flavus. Med. Mycol. 47(Suppl. 1):S261-S270.
18. Patterson, T. F. 2005. The future of animal models of invasive aspergillosis. Med. Mycol. 43(Suppl. 1):S115-S119.
19. Patterson, T. F., W. R. Kirkpatrick, M. White, J. W. Hiemenz, J. R. Wingard, B. Dupont, M. G. Rinaldi, D. A. Stevens, and J. R. Graybill. 2000. Invasive aspergillosis. Disease spectrum, treatment practices, and outcomes. I3 Aspergillus Study Group. Medicine (Baltimore) 79:250-260.
20. Philippe, B., O. Ibrahim-Granet, M. C. Prévost, M. A. Gougerot-Pocidalo, M. Sanchez Perez, A. Van der Meeren, and J.-P. Latgé. 2003. Killing of Aspergillus fumigatus by alveolar macrophages is mediated by reactive oxidant intermediates. Infect. Immun. 71:3034-3042.
21. Schrettl, M., E. Bignell, C. Kragl, C. Joechl, T. Rogers, H. N. Arst, Jr., K. Haynes, and H. Haas. 2004. Siderophore biosynthesis but not reductive iron assimilation is essential for Aspergillus fumigatus virulence. J. Exp. Med. 200:1213-1219.
22. Sheppard, D. C., J. R. Graybill, L. K. Najvar, L. Y. Chiang, T. Doedt, W. R. Kirkpatrick, R. Bocanegra, A. C. Vallor, T. F. Patterson, and S. G. Filler. 2006. Standardization of an experimental murine model of invasive pulmonary aspergillosis. Antimicrob. Agents Chemother. 50:3501-3503.
23. Sheppard, D. C., G. Rieg, L. Y. Chiang, S. G. Filler, J. E. Edwards, Jr., and A. S. Ibrahim. 2004. Novel inhalational murine model of invasive pulmonary aspergillosis. Antimicrob. Agents Chemother. 48:1908-1911.
24. Steinbach, W. J., D. K. Benjamin, Jr., S. A. Trasi, J. L. Miller, W. A. Schell, A. K. Zaas, W. M. Foster, and J. R. Perfect. 2004. Value of an inhalational model of invasive aspergillosis. Med. Mycol. 42:417-425.
25. Tsai, H.-F., Y. C. Chang, R. G. Washburn, M. H. Wheeler, and K. J. Kwon-Chung. 1998. The developmentally regulated alb1 gene of Aspergillus fumigatus: its role in modulation of conidial morphology and virulence. J. Bacteriol. 180:3031-3038.
26. Vallor, A. C., W. R. Kirkpatrick, L. K. Najvar, R. Bocanegra, M. C. Kinney, A. W. Fothergill, M. L. Herrera, B. L. Wickes, J. R. Graybill, and T. F. Patterson. 2008. Assessment of Aspergillus fumigatus burden in pulmonary tissue of guinea pigs by quantitative PCR, galactomannan enzyme immunoassay, and quantitative culture. Antimicrob. Agents Chemother. 52:2593-2598.
27. van Burik, J.-A. H., R. Colven, and D. H. Spach. 1998. Cutaneous aspergillosis. J. Clin. Microbiol. 36:3115-3121.
28. Walsh, T. J. 1998. Primary cutaneous aspergillosis - an emerging infection among immunocompromised patients. Clin. Infect. Dis. 27:453-457.