메뉴 건너뛰기




Volumn 14, Issue SUPPL.3, 2009, Pages 30-35

The use of integrase inhibitors in treatment-experienced patients

Author keywords

[No Author keywords available]

Indexed keywords

INTEGRASE INHIBITOR;

EID: 77951226574     PISSN: 09492321     EISSN: 2047783X     Source Type: Journal    
DOI: 10.1186/2047-783X-14-S3-30     Document Type: Article
Times cited : (7)

References (38)
  • 1
    • 48949097660 scopus 로고    scopus 로고
    • Antiretroviral treatment of adult HIV infection: 2008 recommendations of the International AIDS Society-USA panel
    • 10.1001/jama.300.5.555 18677028
    • Antiretroviral treatment of adult HIV infection: 2008 recommendations of the International AIDS Society-USA panel. Hammer SM, Eron JJ Jr, Reiss P, Schooley RT, Thompson MA, Walmsley S, et al. JAMA 2008 300 5 555 570 10.1001/jama.300.5.555 18677028
    • (2008) JAMA , vol.300 , Issue.5 , pp. 555-570
    • Hammer, S.M.1    Eron Jr., J.J.2    Reiss, P.3    Schooley, R.T.4    Thompson, M.A.5    Walmsley, S.6
  • 4
    • 49449099010 scopus 로고    scopus 로고
    • Emergence of drug resistance in HIV type 1-infected patients after receipt of first-line highly active antiretroviral therapy: A systematic review of clinical trials
    • 10.1086/590943 18662137
    • Emergence of drug resistance in HIV type 1-infected patients after receipt of first-line highly active antiretroviral therapy: a systematic review of clinical trials. Gupta R, Hill A, Sawyer AW, Pillay D, Clin Infect Dis 2008 47 5 712 722 10.1086/590943 18662137
    • (2008) Clin Infect Dis , vol.47 , Issue.5 , pp. 712-722
    • Gupta, R.1    Hill, A.2    Sawyer, A.W.3    Pillay, D.4
  • 5
    • 46349112103 scopus 로고    scopus 로고
    • Antiretroviral drug resistance testing in adult HIV-1 infection: 2008 recommendations of an International AIDS Society-USA
    • Antiretroviral drug resistance testing in adult HIV-1 infection: 2008 recommendations of an International AIDS Society-USA. Hirsch MS, Gunthard HF, Schapiro JM, Brun-Vezinet F, Clotet B, Hammer SM, et al. Clin Infect Dis 2008
    • (2008) Clin Infect Dis
    • Hirsch, M.S.1    Gunthard, H.F.2    Schapiro, J.M.3    Brun-Vezinet, F.4    Clotet, B.5    Hammer, S.M.6
  • 7
    • 34548534109 scopus 로고    scopus 로고
    • Tipranavir: A new option for the treatment of drug-resistant HIV infection
    • DOI 10.1086/520847
    • Tipranavir: a new option for the treatment of drug-resistant HIV infection. Temesgen Z, Feinberg J, Clin Infect Dis 2007 45 6 761 769 10.1086/520847 17712762 (Pubitemid 47381280)
    • (2007) Clinical Infectious Diseases , vol.45 , Issue.6 , pp. 761-769
    • Temesgen, Z.1    Feinberg, J.2
  • 8
    • 33746576313 scopus 로고    scopus 로고
    • Durable efficacy of tipranavir-ritonavir in combination with an optimised background regimen of antiretroviral drugs for treatment-experienced HIV-1-infected patients at 48 weeks in the Randomized Evaluation of Strategic Intervention in multi-drug reSistant patients with Tipranavir (RESIST) studies: An analysis of combined data from two randomised open-label trials
    • DOI 10.1016/S0140-6736(06)69154-X, PII S014067360669154X
    • Durable efficacy of tipranavir-ritonavir in combination with an optimised background regimen of antiretroviral drugs for treatment-experienced HIV-1-infected patients at 48 weeks in the Randomized Evaluation of Strategic Intervention in multi-drug reSistant patients with Tipranavir (RESIST) studies: an analysis of combined data from two randomised open-label trials. Hicks CB, Cahn P, Cooper DA, Walmsley SL, Katlama C, Clotet B, et al. Lancet 2006 368 9534 466 475 10.1016/S0140-6736(06)69154-X 16890833 (Pubitemid 44142769)
    • (2006) Lancet , vol.368 , Issue.9534 , pp. 466-475
    • Hicks, C.B.1    Cahn, P.2    Cooper, D.A.3    Walmsley, S.L.4    Katlama, C.5    Clotet, B.6    Lazzarin, A.7    Johnson, M.A.8    Neubacher, D.9    Mayers, D.10    Valdez, H.11
  • 12
    • 59849094872 scopus 로고    scopus 로고
    • Efficacy and safety of etravirine (TMC125) in treatment-experienced HIV-1-infected patients: 48-week results of a phase IIb trial
    • Efficacy and safety of etravirine (TMC125) in treatment-experienced HIV-1-infected patients: 48-week results of a phase IIb trial. Cohen CJ, Berger DS, Blick G, Grossman HA, Jayaweera DT, Shalit P, et al. AIDS 2008
    • (2008) AIDS
    • Cohen, C.J.1    Berger, D.S.2    Blick, G.3    Grossman, H.A.4    Jayaweera, D.T.5    Shalit, P.6
  • 13
    • 43749121302 scopus 로고    scopus 로고
    • DUET-1: Week-48 results of a phase III randomized double-blind trial to evaluate the efficacy and safety of TMC125 vs placebo in 612 treatment-experienced HIV-1-infected patients
    • DUET-1: week-48 results of a phase III randomized double-blind trial to evaluate the efficacy and safety of TMC125 vs placebo in 612 treatment-experienced HIV-1-infected patients. Haubrich R, Cahn P, Grinsztein B, Lalezari J, Madruga J, Mills A, et al. 15th Conference on Retroviruses and Opportunistic Infections 2008
    • (2008) 15th Conference on Retroviruses and Opportunistic Infections
    • Haubrich, R.1    Cahn, P.2    Grinsztein, B.3    Lalezari, J.4    Madruga, J.5    Mills, A.6
  • 14
    • 47949120697 scopus 로고    scopus 로고
    • Raltegravir with optimized background therapy for resistant HIV-1 infection
    • 10.1056/NEJMoa0708975 18650512
    • Raltegravir with optimized background therapy for resistant HIV-1 infection. Steigbigel RT, Cooper DA, Kumar PN, Eron JE, Schechter M, Markowitz M, et al. N Engl J Med 2008 359 4 339 354 10.1056/NEJMoa0708975 18650512
    • (2008) N Engl J Med , vol.359 , Issue.4 , pp. 339-354
    • Steigbigel, R.T.1    Cooper, D.A.2    Kumar, P.N.3    Eron, J.E.4    Schechter, M.5    Markowitz, M.6
  • 15
    • 47949114939 scopus 로고    scopus 로고
    • Subgroup and resistance analyses of raltegravir for resistant HIV-1 infection
    • 10.1056/NEJMoa0708978 18650513
    • Subgroup and resistance analyses of raltegravir for resistant HIV-1 infection. Cooper DA, Steigbigel RT, Gatell JM, Rockstroh JK, Katlama C, Yeni P, et al. N Engl J Med 2008 359 4 355 365 10.1056/NEJMoa0708978 18650513
    • (2008) N Engl J Med , vol.359 , Issue.4 , pp. 355-365
    • Cooper, D.A.1    Steigbigel, R.T.2    Gatell, J.M.3    Rockstroh, J.K.4    Katlama, C.5    Yeni, P.6
  • 16
    • 54549099338 scopus 로고    scopus 로고
    • HIV-2 integrase gene polymorphism and phenotypic susceptibility of HIV-2 clinical isolates to the integrase inhibitors raltegravir and elvitegravir in vitro
    • HIV-2 integrase gene polymorphism and phenotypic susceptibility of HIV-2 clinical isolates to the integrase inhibitors raltegravir and elvitegravir in vitro. Roquebert B, Damond F, Collin G, Matheron S, Peytavin G, Benard A, et al. J Antimicrob Chemother 2008
    • (2008) J Antimicrob Chemother
    • Roquebert, B.1    Damond, F.2    Collin, G.3    Matheron, S.4    Peytavin, G.5    Benard, A.6
  • 17
    • 54849146700 scopus 로고    scopus 로고
    • Maraviroc for previously treated patients with R5 HIV-1 infection
    • 10.1056/NEJMoa0803152 18832244
    • Maraviroc for previously treated patients with R5 HIV-1 infection. Gulick RM, Lalezari J, Goodrich J, Clumeck N, DeJesus E, HORBAN A, et al. N Engl J Med 2008 359 14 1429 1441 10.1056/NEJMoa0803152 18832244
    • (2008) N Engl J Med , vol.359 , Issue.14 , pp. 1429-1441
    • Gulick, R.M.1    Lalezari, J.2    Goodrich, J.3    Clumeck, N.4    Dejesus, E.5    Horban, A.6
  • 18
    • 48949097660 scopus 로고    scopus 로고
    • Antiretroviral treatment of adult HIV infection: 2008 recommendations of the International AIDS Society-USA panel
    • 10.1001/jama.300.5.555 18677028
    • Antiretroviral treatment of adult HIV infection: 2008 recommendations of the International AIDS Society-USA panel. Hammer SM, Eron JJ Jr, Reiss P, Schooley RT, THOMPSON MA, Walmsley S, et al. JAMA 2008 300 5 555 570 10.1001/jama.300.5.555 18677028
    • (2008) JAMA , vol.300 , Issue.5 , pp. 555-570
    • Hammer, S.M.1    Eron Jr., J.J.2    Reiss, P.3    Schooley, R.T.4    Thompson, M.A.5    Walmsley, S.6
  • 19
    • 67650694310 scopus 로고    scopus 로고
    • A double-blind, placebo-controlled trial of maraviroc in treatment-experienced patients infected with non-R5 HIV-1
    • 10.1086/598965 19432546
    • A double-blind, placebo-controlled trial of maraviroc in treatment-experienced patients infected with non-R5 HIV-1. Saag M, Goodrich J, Fatkenheuer G, Clotet B, Clumeck N, Sullivan J, et al. J Infect Dis 2009 199 11 1638 1647 10.1086/598965 19432546
    • (2009) J Infect Dis , vol.199 , Issue.11 , pp. 1638-1647
    • Saag, M.1    Goodrich, J.2    Fatkenheuer, G.3    Clotet, B.4    Clumeck, N.5    Sullivan, J.6
  • 20
    • 47949120697 scopus 로고    scopus 로고
    • Raltegravir with optimized background therapy for resistant HIV-1 infection
    • 10.1056/NEJMoa0708975 18650512
    • Raltegravir with optimized background therapy for resistant HIV-1 infection. Steigbigel RT, Cooper DA, Kumar PN, Eron JE, Schechter M, Markowitz M, et al. N Engl J Med 2008 359 4 339 354 10.1056/NEJMoa0708975 18650512
    • (2008) N Engl J Med , vol.359 , Issue.4 , pp. 339-354
    • Steigbigel, R.T.1    Cooper, D.A.2    Kumar, P.N.3    Eron, J.E.4    Schechter, M.5    Markowitz, M.6
  • 21
    • 63649087422 scopus 로고    scopus 로고
    • Raltegravir: The First HIV Type 1 Integrase Inhibitor
    • Raltegravir: The First HIV Type 1 Integrase Inhibitor. Hicks C, Gulick RM, Clin Infect Dis 2009
    • (2009) Clin Infect Dis
    • Hicks, C.1    Gulick, R.M.2
  • 22
    • 66149137187 scopus 로고    scopus 로고
    • Lack of a Clinically Important Effect of Moderate Hepatic Insufficiency and Severe Renal Insufficiency on Raltegravir Pharmacokinetics
    • Lack of a Clinically Important Effect of Moderate Hepatic Insufficiency and Severe Renal Insufficiency on Raltegravir Pharmacokinetics. Iwamoto M, Hanley WD, Petry AS, Friedman EJ, Kost JT, Breidinger SA, et al. Antimicrob Agents Chemother 2009
    • (2009) Antimicrob Agents Chemother
    • Iwamoto, M.1    Hanley, W.D.2    Petry, A.S.3    Friedman, E.J.4    Kost, J.T.5    Breidinger, S.A.6
  • 24
    • 34147136222 scopus 로고    scopus 로고
    • Safety and efficacy of the HIV-1 integrase inhibitor raltegravir (MK-0518) in treatment-experienced patients with multidrug-resistant virus: A phase II randomised controlled trial
    • DOI 10.1016/S0140-6736(07)60597-2, PII S0140673607605972
    • Safety and efficacy of the HIV-1 integrase inhibitor raltegravir (MK-0518) in treatment-experienced patients with multidrug-resistant virus: a phase II randomised controlled trial. Grinsztejn B, Nguyen BY, Katlama C, Gatell JM, Lazzarin A, Vittecoq D, et al. Lancet 2007 369 9569 1261 1269 10.1016/S0140-6736(07)60597-2 17434401 (Pubitemid 46553846)
    • (2007) Lancet , vol.369 , Issue.9569 , pp. 1261-1269
    • Grinsztejn, B.1    Nguyen, B.-Y.2    Katlama, C.3    Gatell, J.M.4    Lazzarin, A.5    Vittecoq, D.6    Gonzalez, C.J.7    Chen, J.8    Harvey, C.M.9    Isaacs, R.D.10
  • 25
    • 77949381837 scopus 로고    scopus 로고
    • Long-term efficacy and safety of the HIV integrase inhibitor raltegravir in patients with limited treatment options in a phase II study
    • Long-term efficacy and safety of the HIV integrase inhibitor raltegravir in patients with limited treatment options in a phase II study. Gatell JM, Katlama C, Grinsztejn B, Eron JJ, Lazzarin A, Vittecoq D, et al. J Acquir Immune Defic Syndr 2009
    • (2009) J Acquir Immune Defic Syndr
    • Gatell, J.M.1    Katlama, C.2    Grinsztejn, B.3    Eron, J.J.4    Lazzarin, A.5    Vittecoq, D.6
  • 26
    • 34147136222 scopus 로고    scopus 로고
    • Safety and efficacy of the HIV-1 integrase inhibitor raltegravir (MK-0518) in treatment-experienced patients with multidrug-resistant virus: A phase II randomised controlled trial
    • DOI 10.1016/S0140-6736(07)60597-2, PII S0140673607605972
    • Safety and efficacy of the HIV-1 integrase inhibitor raltegravir (MK-0518) in treatment-experienced patients with multidrug-resistant virus: a phase II randomised controlled trial. Grinsztejn B, Nguyen BY, Katlama C, Gatell JM, Lazzarin A, Vittecoq D, et al. Lancet 2007 369 1261 1269 10.1016/S0140-6736(07)60597-2 17434401 (Pubitemid 46553846)
    • (2007) Lancet , vol.369 , Issue.9569 , pp. 1261-1269
    • Grinsztejn, B.1    Nguyen, B.-Y.2    Katlama, C.3    Gatell, J.M.4    Lazzarin, A.5    Vittecoq, D.6    Gonzalez, C.J.7    Chen, J.8    Harvey, C.M.9    Isaacs, R.D.10
  • 27
    • 47949120697 scopus 로고    scopus 로고
    • Raltegravir with optimized background therapy for resistant HIV-1 infection
    • 10.1056/NEJMoa0708975 18650512
    • Raltegravir with optimized background therapy for resistant HIV-1 infection. Steigbigel RT, Cooper DA, Kumar PN, Eron JE, Schechter M, Markowitz M, et al. N Engl J Med 2008 359 4 339 354 10.1056/NEJMoa0708975 18650512
    • (2008) N Engl J Med , vol.359 , Issue.4 , pp. 339-354
    • Steigbigel, R.T.1    Cooper, D.A.2    Kumar, P.N.3    Eron, J.E.4    Schechter, M.5    Markowitz, M.6
  • 28
    • 47949114939 scopus 로고    scopus 로고
    • Subgroup and resistance analyses of raltegravir for resistant HIV-1 infection
    • 10.1056/NEJMoa0708978 18650513
    • Subgroup and resistance analyses of raltegravir for resistant HIV-1 infection. Cooper DA, Steigbigel RT, Gatell JM, Rockstroh JK, Katlama C, Yeni P, et al. N Engl J Med 2008 359 355 365 10.1056/NEJMoa0708978 18650513
    • (2008) N Engl J Med , vol.359 , pp. 355-365
    • Cooper, D.A.1    Steigbigel, R.T.2    Gatell, J.M.3    Rockstroh, J.K.4    Katlama, C.5    Yeni, P.6
  • 29
    • 75749107023 scopus 로고    scopus 로고
    • Long-term efficacy and safety of raltegravir combined with optimized background therapy in treatment-experienced patients with resistant HIV infection: Week 96 results of the BENCHMRK 1 and 2 phase III trials
    • Long-term efficacy and safety of raltegravir combined with optimized background therapy in treatment-experienced patients with resistant HIV infection: Week 96 results of the BENCHMRK 1 and 2 phase III trials. Steigbigel R, Cooper DA, Teppler H, Eron JJ, Gatell JM, Kumar PN, et al. Clin Infect Dis 2009
    • (2009) Clin Infect Dis
    • Steigbigel, R.1    Cooper, D.A.2    Teppler, H.3    Eron, J.J.4    Gatell, J.M.5    Kumar, P.N.6
  • 30
    • 84870565142 scopus 로고    scopus 로고
    • Efficacy and safety of raltegravir plus etravirine and darunavir/ritonavir in treatment experienced patients with multidrug resistant virus: 48 weeks results from the ARNS 139 TRIO trial. 5th IAS
    • Efficacy and safety of raltegravir plus etravirine and darunavir/ritonavir in treatment experienced patients with multidrug resistant virus: 48 weeks results from the ARNS 139 TRIO trial. 5th IAS. Fagard C, Descamps D, Dubar V, Colin C, Taburet AM, Roquebert B, Cape Town 2009
    • (2009) Cape Town
    • Fagard, C.1    Descamps, D.2    Dubar, V.3    Colin, C.4    Taburet, A.M.5    Roquebert, B.6
  • 31
    • 71049149300 scopus 로고    scopus 로고
    • Raltegravir, Etravirine, and Ritonavir-Boosted Darunavir: A Safe and Successful Rescue Regimen for Multidrug-Resistant HIV-1 Infection
    • Raltegravir, Etravirine, and Ritonavir-Boosted Darunavir: A Safe and Successful Rescue Regimen for Multidrug-Resistant HIV-1 Infection. Imaz A, Del Saz SV, Ribas MA, Curran A, Caballero E, Falco V, et al. J Acquir Immune Defic Syndr 2009
    • (2009) J Acquir Immune Defic Syndr
    • Imaz, A.1    Del Saz, S.V.2    Ribas, M.A.3    Curran, A.4    Caballero, E.5    Falco, V.6
  • 32
    • 50949112147 scopus 로고    scopus 로고
    • Outcomes of multidrug-resistant patients switched from enfuvirtide to raltegravir within a virologically suppressive regimen
    • 10.1097/QAD.0b013e328302f3b5 18525270
    • Outcomes of multidrug-resistant patients switched from enfuvirtide to raltegravir within a virologically suppressive regimen. Harris M, Larsen G, Montaner JS, AIDS 2008 22 10 1224 1226 10.1097/QAD.0b013e328302f3b5 18525270
    • (2008) AIDS , vol.22 , Issue.10 , pp. 1224-1226
    • Harris, M.1    Larsen, G.2    Montaner, J.S.3
  • 33
    • 68049148420 scopus 로고    scopus 로고
    • Virologic outcomes of changing enfuvirtide to raltegravir in HIV-1 patients well controlled on an enfuvirtide based regimen: 24-week results of the CHEER study
    • 10.1097/QAI.0b013e3181ae35de 19487951
    • Virologic outcomes of changing enfuvirtide to raltegravir in HIV-1 patients well controlled on an enfuvirtide based regimen: 24-week results of the CHEER study. Towner W, Klein D, Kerrigan HL, Follansbee S, Yu K, Horberg M, J Acquir Immune Defic Syndr 2009 51 4 367 373 10.1097/QAI.0b013e3181ae35de 19487951
    • (2009) J Acquir Immune Defic Syndr , vol.51 , Issue.4 , pp. 367-373
    • Towner, W.1    Klein, D.2    Kerrigan, H.L.3    Follansbee, S.4    Yu, K.5    Horberg, M.6
  • 34
    • 84870563492 scopus 로고    scopus 로고
    • Switching from stable lopinavir/ritonavir based to raltegravir based combination antiretroviral therapy resulted in superior lipid profile at week 12 but did not demonstrate non-inferior efficacy at week 24. 16th Conference on Retrovirus Opportunistic Infections
    • Switching from stable lopinavir/ritonavir based to raltegravir based combination antiretroviral therapy resulted in superior lipid profile at week 12 but did not demonstrate non-inferior efficacy at week 24. 16th Conference on Retrovirus Opportunistic Infections. Eron J, Andrade JMJ, Zajdenverg R, Workman J, Cooper D, Young B, Montreal 2009
    • (2009) Montreal
    • Eron, J.1    Andrade, J.M.J.2    Zajdenverg, R.3    Workman, J.4    Cooper, D.5    Young, B.6
  • 35
    • 67249121143 scopus 로고    scopus 로고
    • Treatment intensification does not reduce residual HIV-1 viremia in patients on highly active antiretroviral therapy
    • 10.1073/pnas.0903107106 19470482
    • Treatment intensification does not reduce residual HIV-1 viremia in patients on highly active antiretroviral therapy. Dinoso JB, Kim SY, Wiegand AM, Palmer SE, Gange SJ, Cranmer L, et al. Proc Natl Acad Sci USA 2009 106 23 9403 9408 10.1073/pnas.0903107106 19470482
    • (2009) Proc Natl Acad Sci USA , vol.106 , Issue.23 , pp. 9403-9408
    • Dinoso, J.B.1    Kim, S.Y.2    Wiegand, A.M.3    Palmer, S.E.4    Gange, S.J.5    Cranmer, L.6
  • 36
    • 84870556686 scopus 로고    scopus 로고
    • Antiretroviral intensification does not reduce persistent HIV viremia on therapy. XIII International Drug Resistance Workshop
    • Antiretroviral intensification does not reduce persistent HIV viremia on therapy. XIII International Drug Resistance Workshop. Dinoso JB, Jones J, McMahon D, Fort Myers, Florida 2009
    • (2009) Fort Myers, Florida
    • Dinoso, J.B.1    Jones, J.2    McMahon, D.3
  • 38
    • 47949114939 scopus 로고    scopus 로고
    • Subgroup and resistance analyses of raltegravir for resistant HIV-1 infection
    • 10.1056/NEJMoa0708978 18650513
    • Subgroup and resistance analyses of raltegravir for resistant HIV-1 infection. Cooper DA, Steigbigel RT, Gatell JM, Rockstroh JK, Katlama C, Yeni P, et al. N Engl J Med 2008 359 4 355 365 10.1056/NEJMoa0708978 18650513
    • (2008) N Engl J Med , vol.359 , Issue.4 , pp. 355-365
    • Cooper, D.A.1    Steigbigel, R.T.2    Gatell, J.M.3    Rockstroh, J.K.4    Katlama, C.5    Yeni, P.6


* 이 정보는 Elsevier사의 SCOPUS DB에서 KISTI가 분석하여 추출한 것입니다.