The influence of 1800 MHz GSM-like signals on hepatic oxidative DNA and lipid damage in nonpregnant, pregnant, and newly born rabbits

Cell Biochemistry and Biophysics

Volumn 56, Issue 1, 2010, Pages 39-47

  Tomruk, Arin ^a   Guler, Goknur ^a   Dincel, Aylin Sepici ^a  

^a GAZI UNIVERSITY   (Turkey)

Author keywords

8 OHdG; Liver; MDA; Pregnant; Rabbit; Radiofrequency

Indexed keywords

8 HYDROXYDEOXYGUANOSINE; 8-HYDROXY-2'-DEOXYGUANOSINE; DEOXYGUANOSINE; DRUG DERIVATIVE; FERROUS ION; FREE RADICAL; MALONALDEHYDE;

ANIMAL; ARTICLE; DNA DAMAGE; FEMALE; LIPID METABOLISM; LIPID PEROXIDATION; LIVER; MALE; METABOLISM; MOBILE PHONE; NEWBORN; OXIDATIVE STRESS; PATHOLOGY; PREGNANCY; RABBIT; RADIATION EXPOSURE; RADIOFREQUENCY RADIATION;

ANIMALS; ANIMALS, NEWBORN; CELLULAR PHONE; DEOXYGUANOSINE; DNA DAMAGE; FEMALE; FERROUS COMPOUNDS; FREE RADICALS; LIPID METABOLISM; LIPID PEROXIDATION; LIVER; MALE; MALONDIALDEHYDE; OXIDATIVE STRESS; PREGNANCY; RABBITS; RADIO WAVES;

EID: 77951225661     PISSN: 10859195     EISSN: None     Source Type: Journal    
DOI: 10.1007/s12013-009-9068-1     Document Type: Article

References (45)

1. Challis, L. J. (2005). Mechanisms for interaction between RF fields and biological tissues. Bioelectromagnetics, S7, S98-S106
2. Polk, C., & Postow, E. (1996). Handbook of biological effects of electromagnetic fields (2nd ed.). Florida, USA: CRC Press.
3. Hietanen, M. (2006). Health risks of exposure to non-ionizing radiation myths or science-based evidence. La Medicina del lavoro, 97(2), 184-188
4. Blettner, M., Schlehofer, B., Breckenkamp, J., Kowall, B., Schmiedel, S., Reis, U., et al. (2009). Mobile phone base stations and adverse health effects: phase 1 of a population-based, crosssectional study in Germany. Occupational and Environmental Medicine, 66, 118-123
5. Viel, J. F., Clerc, S., Barrera, C., Rymzhanova, R., Moissonnier, M., Hours, M., et al. (2009). Residential exposure to radiofrequency fields from mobile phone base stations, and broadcast transmitters: A population-based survey with personal meter. Occupational and Environmental Medicine, 66, 550-556
6. Garaj-Vrhovac, V., Fucic, A., & Horvat, D. (1992). The correlation between the frequency of nuclei and specific chromosome aberrations in human lymphocytes exposed to microwave radiation in vitro. Mutation Research, 281(3), 181-186
7. Sarkar, S., Ali, S., & Behari, J. (1994). Effect of low power microwave on the mouse genome: a direct DNA analysis. Mutation Research, 320(1-2), 141-147
8. Lai, H., & Singh, N. P. (1997). Melatonin and spin-trap compound block radiofrequency electromagnetic radiation- induced DNA strand breaks in rat brain cells. Bioelectromagnetics, 18, 446-454
9. Garaj-Vrhovac, V., & Orescanin, V. (2009). Assessment of DNA sensitivity in peripheral blood leukocytes after occupational exposure to microwave radiation: The alkaline comet assay and chromatid breakage assay. Cell Biology and Toxicology, 25, 33-43
10. Belyaev, I. Y., Markova, E., Hillert, L., Malmgren, L. O., & Persson, B. R. (2009). Microwaves from UMTS/GSM mobile phones induce long-lasting inhibition of 53BP1/gamma-H2AX DNA repair foci in human lymphocytes. Bioelectromagnetics, 30, 129-141
11. Hocking, B., & Westerman, R. (2001). Neurological abnormalities associated with CDMA exposure. Occupational Medicine, 51(6), 410-413
12. Leszczynski, D., Joenvaara, S., Reivinien, J., & Kuokka, R. (2002). Non-thermal activation of the hsp27/p38MAPK stress pathway by mobile phone radiation in human endothelial cells: molecular mechanism for cancer and blood brain barrier-related effects. Differentiation, 70, 120-129
13. Tian, F., Nakahara, T., Wake, K., Taki, M., & Miyokoshi, J. (2002). Exposureto 2.45 GHz electromagnetic fields induces hsp70 at a high SAR of more than 20 W/kg but not at 5 W/kg in human glioma MO54 cells. International Journal of Radiation Biology, 78(5), 433-440
14. Lopez-Martin, M. E., Brogains, J., Relova-Quinteiro, J. L., Cadarso-Suarez, C., Jorge-Barreiro, F. J., & Ares-Pena, F. J. (2009). The action of pulse-modulated GSM radiation increases regional changes in brain activity and c-Fos expression in cortical and subcortical areas in a rat model of picrotoxin-induced seizure proneness. Journal of Neuroscience Research, 87, 1484-1499
15. Hardell, L., Carlberg, M., & Hansson Mild, K. (2009). Epidemiological evidence for an association between use of wireless phones and tumor diseases. Pathophysiology, 16, 113-122
16. Marinelli, F., La Sala, D., Cicciotti, G., Cattini, L., Trimarchi, C., Putti, S., et al. (2004). Exposure to 900 MHz electromagnetic field induces an unbalance between pro-apoptotic and pro-survival signals in T-lymphoblastoid leukemia CCRF-CEM cells. Journal of Cellular Physiology, 198, 324-332
17. Trosic, I., Busljeta, I., & Modlic, B. (2004). Investigation of genotoxic effect of microwave irradiation in rat bone marrow cells: In vivo exposure. Mutagenesis, 19(5), 361-364
18. Lantow, M., Lupke, M., Frahm, J., Mattsson, M. O., Kuster, N., & Simko, M. (2006). ROS release and HSp 70 expression after exposure to 1800 MHz radiofrequency electromagnetic fields in primary human monocytes and lymphocytes. Radiation and Environmental Biophysics, 45, 55-62
19. Sanchez, S., Milochau, A., Ruffie, G., Poulletier de Gannes, F., Lagroye, I., Haro, E., et al. (2006). Human skin cell stress response to GSM-900 mobile phone signals: In vitro study on isolated primary cells and reconstructed epidermis. The FEBS Journal, 273, 5491-5507
20. Valavanidis, A., Vlachogianni, T., & Fiotakis, C. (2009). 8- hydroxy-20 -deoxyguanosine (8-OHdG): A critical biomarker of oxidative stress and carcinogenesis. Journal of Environmental Science and Health Part C, 27, 120-139
21. Janero, D. R. (1990). Malondialdehyde and thiobarbituric acidreactivity as diagnostic indices of lipid peroxidation and peroxidative tissue injury. Free Radical Biology and Medicine, 9, 515-540
22. Bonnes-Taourel, D., Guerin, M. C., & Torreilles, J. (1992). Is malondialdehyde a valuable indicator of lipid peroxidation? Biochemical Pharmacology, 44, 985-988
23. Esterbauer, H., Schaur, R. J., & Zollner, H. (1991). Chemistry and biochemistry of 4-hydroxynonenal, malondialdehyde and related aldehydes. Free Radical Biology and Medicine, 11, 81-128
24. Chamblee, B. B., Timm, T. C., Hunsaker, L. A., & Vander Jagt, D. L. (2000). Relationship of oxidative stress indices to decreased LDL-cholesterol after acute myocardial infarction. Clinical Biochemistry, 33, 423-426
25. Heynick, L. N., & Merritt, J. H. (2003). Radiofrequency fields and teratogenesis. Bioelectromagnetics (Suppl 6), S174-S186
26. Panagopoulos, D. J., Chavdoula, E. D., Nezis, I. P., & Margaritis, L. H. (2007). Cell Death induced by GSM 900- MHz and DCS 1800-MHz mobile telephony radiation. Mutation Research, 626, 69-78
27. Mihara, M., & Uchiyama, M. (1978). Determination of malonaldehyde precursor in tissues by thiobarbituric acid test. Analytical Biochemistry, 86, 271-278
28. Hermes-Lima, M., Willmore, G. W., & Storey, B. K. (1995). Quantification of lipid peroxidation in tissue extracts based on Fe(III) Xylenol orange complex formation. Free Radical Biology and Medicine, 19, 271-280
29. Floyd, R. A., Watson, J. J., Wong, P. K., Altmiller, D. H., & Rickard, R. C. (1986). Hydroxyl free radical adduct of deoxyguanosine: Sensitive detection and mechanisms of formation. Free Radical Research Communications, 1(3), 163-172
30. Halliwell, B., & Dizdaroglu, M. (1992). Commentary. The measurement of oxidative damage to DNA by HPLC and GC/MS techniques. Free Radical Research Communications, 16(2), 75-87
31. Hamilton, M. L., Guo, Z. M., Fuller, C. D., Van Remmen, H., Ward, W. F., Austad, S. N., et al. (2001). A reliable assessment of 8-oxo-2-deoxyguanosine levels in nuclear and mitochondrial DNA using the sodium iodide method to isolate DNA. Nucleic Acids Research, 29, 2117-2126
32. Dimbylow, P. (2007). SAR in mother and foetus for RF plane wave irradiation. Physics in Medicine and Biology, 52, 3791-3802
33. Lary, J. M., Conover, D. L., Johnson, P. H., & Hornung, R. W. (1986). Dose-response relationship body temperature and birth defects in radiofrequency-irradiation rats. Bioelectromagnetics, 7, 141-149
34. Wangemann, R. T., & Cleary, S. F. (1976). The in vivo Effects of 2.45 GHz microwave radiation on rabbit serum components and sleeping environmental times. Radiation and Environmental Biophysics, 13, 89-103
35. Fayez, I., Marai, M., Alnaimy, A., & Habeeb, M. (1994). Thermoregulation in rabbits. In M. Baselga & I. F. M. Marai (Eds.), Rabbit production in hot climates. Zaragoza: CIHEAM-IAMZ, pp. 33-41: 22 ref. (Cahiers Options Méditerranéennes; v. 8), 1. International Conference of rabbit production in hot climates, 1994/09/06-08, Cairo (Egypt).
36. Belyaev, I. (2005). Non-thermal biological effects of microwaves. Microwave Review, 11, 13-29
37. Belyaev, I. (2005). Nonthermal biological effects of microwaves: Current knowledge, further perspective, and urgent needs. Electromagnetic Biology and Medicine, 24, 375-403
38. Laurence, J. A., French, P. W., Lindner, R. A., & McKenzie, D. R. (2000). Biological effects of electromagnetic fields- Microwave radiation on protein conformation. Journal of Theoretical Biology, 206, 291-298
39. Astumian, R. D. (2003). Adiabatic pumping mechanism for ion motive ATPases. Physical Review Letters, 91(11), 118102
40. Erkoç, F., & Erkoç, Ş. (2002). Structural and electronic properties of guanine and guanosine. Journal of Molecular Structure, 405-411
41. Cooke, M. S., Evans, M. D., Dizdaroglu, M., & Lunec, J. (2003). Oxidative DNA damage: mechanisms, mutation and disease. The FASEB Journal, 17, 1195-1214
42. Auroma, O. I., Halliwell, B., & Dizdaroglu, M. (1989). Iron dependent modification of bases in DNA by superoxide radical generating system hypoxanthine, xanthine oxidase. Journal of Biological Chemistry, 264, 1324-1328
43. Meral, I., Mert, H., Mert, N., Deger, Y., Yoruk, I., Yetkin, A., et al. (2007). Effects of 900 MHz electromagnetic field emitted from cellular phone on brain oxidative stress and some levels of guinea pigs. Brain Research, 1169, 120-124
44. Toescu, V., Nuttall, S. L., Martin, U., Kendall, M. J., & Dunne, F. (2002). Oxidative stress and normal pregnancy. Clinical Endocrinology, 57, 609-613
45. Kim, Y. J., Hong, Y. C., Lee, K. H., Park, H. J., Park, E. A., Moon, H. S., et al. (2005). Oxidative stress in pregnant women and birth weight reduction. Reproductive Toxicology, 19, 487-492.