A comparison of multimodality treatment: Two or four courses of paclitaxel plus cisplatin or S-1 plus cisplatin followed by surgery for locally advanced gastric cancer, a randomized phase II trial (COMPASS)

Japanese Journal of Clinical Oncology

Volumn 40, Issue 4, 2010, Pages 369-372

  Yoshikawa, Takaki ^a   Tsuburaya, Akira ^a   Morita, Satoshi ^b   Kodera, Yasuhiro ^c   Ito, Seiji ^d   Cho, Haruhiko ^a   Miyashita, Yumi ^e   Sakamoto, Junichi ^c  

^a KANAGAWA CANCER CENTER   (Japan)

^b YOKOHAMA CITY UNIVERSITY MEDICAL CENTER   (Japan)

^c NAGOYA UNIVERSITY GRADUATE SCHOOL OF MEDICINE   (Japan)

^d AICHI CANCER CENTER HOSPITAL   (Japan)

^e Nonprofit Organization ECRIN   (Japan)

Author keywords

Course; Gastric cancer; Neoadjuvant chemotherapy; Phase II; Surgery

Indexed keywords

5 CHLORO 2,4 DIHYDROXYPYRIDINE PLUS OXONATE POTASSIUM PLUS TEGAFUR; CISPLATIN; PACLITAXEL; ANTINEOPLASTIC AGENT; OXONIC ACID; S 1 (COMBINATION); TEGAFUR;

ADVANCED CANCER; ARTICLE; CANCER ADJUVANT THERAPY; CANCER COMBINATION CHEMOTHERAPY; CLINICAL TRIAL; CONTROLLED CLINICAL TRIAL; GASTRECTOMY; HUMAN; LYMPHADENECTOMY; MULTIMODALITY CANCER THERAPY; OVERALL SURVIVAL; PHASE 2 CLINICAL TRIAL; POSTOPERATIVE PERIOD; RANDOMIZED CONTROLLED TRIAL; SAMPLE SIZE; STOMACH CANCER; ABDOMINAL SURGERY; ADJUVANT THERAPY; CONTROLLED STUDY; DRUG COMBINATION; PATHOLOGY; STOMACH TUMOR;

ANTINEOPLASTIC COMBINED CHEMOTHERAPY PROTOCOLS; CISPLATIN; COMBINED MODALITY THERAPY; DIGESTIVE SYSTEM SURGICAL PROCEDURES; DRUG COMBINATIONS; HUMANS; NEOADJUVANT THERAPY; OXONIC ACID; PACLITAXEL; STOMACH NEOPLASMS; TEGAFUR;

EID: 77951222218     PISSN: 03682811     EISSN: 14653621     Source Type: Journal    
DOI: 10.1093/jjco/hyp178     Document Type: Article

References (13)

1. Torrado J, Santiseban A, Ruiz-Ederra J. Genetic susceptibility to gastric cancer. Hepatogastroenterology 2001;48:1544-7.
2. Sasako M. Principles of surgical treatment for curable gastric cancer. J Clin Oncol 2003;21:274-5.
3. Sakuramoto S, Sasako M, Yamaguchi T, Kinoshita T, Fujii M, Nashimoto A, et al. Adjuvant chemotherapy for gastric cancer with S-1, an oral fluoropyrimidine. N Engl J Med 2007;357:1810-20.
4. Ott K, Lordick F, Hermann K, Krause BJ, Schuhmacher C, Siewert JR. The new credo: induction chemotherapy in locally advanced gastric cancer: consequences for surgical strategies. Gastric Cancer 2008;11:1-9.
5. Cunningham D, Allum WH, Stenning SP, Thompson JN, Van de Velde CJ, Nicolson M, et al. Perioperative chemotherapy versus surgery alone for resectable gastroesophageal cancer. N Engl J Med 2006;355:11-20.
6. Boige V, Pignon J, Saint-Aubert B, Lasser P, Conroy T, Bouche O, et al. Final results of a randomized trial comparing preoperative 5-fluorouracil (F)/cisplatin (P) to surgery alone in adenocarcinoma of stomach and lower esophagus (ASLE): FNLCC ACCORD07-FFCD 9703 trial (abstract). J Clin Oncol 2007;25(Suppl 18):A-4510, 200s.
7. Yamaguchi K, Tada M, Horikoshi N, Otani T, Takiuchi H, Saitoh S, et al. Phase II study of paclitaxel with 3-h infusion patients with advanced gastric cancer. Gastric Cancer 2002;5:90-5.
8. Kobayashi M, Oba K, Sakamoto J, Kondo K, Nagata N, Okabayashi T, et al. Pharmacokinetic study of weekly administration dose of paclitaxel in patients with advanced or recurrent gastric cancer in Japan. Gastric Cancer 2007;10:52-7.
9. Sakamoto J, Matsui T, Kodera Y. Paclitaxel chemotherapy for the treatment of gastric cancer. Gastric Cancer 2009;12:69-78.
10. Tsuburaya A, Sakamoto J, Morita S, Kodera Y, Kobayashi M, Miyashita Y, et al. A randomized Phase III trial of post-operative adjuvant oral fluoropyrimidine versus sequential paclitaxel/oral fluoropyrimidine; and UFT versus S1 for T3/T4 gastric carcinoma: The Stomach Cancer Adjuvant Multi-institutional Trial Group (Samit) Trial. Jpn J Clin Oncol 2005;35:672-5.
11. Nagata N, Kimura M, Hirabayashi N, Tsuburaya A, Murata T, Kondo K, et al. Phase II study of weekly paclitaxel and cisplatin combination chemotherapy for unresectable or recurrent gastric cancer. Hepatogastroenterology 2008;55:1846-50.
12. Nagata N, Tsuburaya A, Cho H, Hirabayashi N, Kobayashi M, Matsui T, et al. Phase II study of preoperative chemotherapy with paclitaxel plus cisplatin (CDDP) for advanced gastric cancer (abstract). Proceeding of 34th European Society of Medical Oncology (ESMO) Multidisciplinary Congress, 20-24 September 2009, Berlin, Germany.
13. Habermann CR, Weiss F, Riecken R, Honarpisheh H, Bohnacker S, Staedtler S, et al. Preoperative staging of gastric adenocarcinoma: comparison of helical CT and endoscopic US. Radiology 2004;230:465-70.