Antitumor effects of a recombinant pseudotype baculovirus expressing Apoptin in vitro and in vivo

International Journal of Cancer

Volumn 126, Issue 11, 2010, Pages 2741-2751

  Pan, Yongfei ^a   Fang, Liurong ^a   Fan, Huiying ^a   Luo, Rui ^a   Zhao, Qian ^a   Chen, Huanchun ^a   Xiao, Shaobo ^a  

^a HUAZHONG AGRICULTURAL UNIVERSITY   (China)

Author keywords

Apoptin; Cancer; Gene therapy; Pseudotype baculovirus

Indexed keywords

APOPTIN; BACULOVIRUS VECTOR; CAPSID PROTEIN; VP3 PROTEIN, CHICKEN ANEMIA VIRUS;

ANIMAL EXPERIMENT; ANIMAL MODEL; ANIMAL TISSUE; ANTINEOPLASTIC ACTIVITY; ARTICLE; CANCER CELL CULTURE; CANCER INHIBITION; CONTROLLED STUDY; FEMALE; HUMAN; HUMAN CELL; LIVER CELL CARCINOMA; MOUSE; NONHUMAN; PRIORITY JOURNAL; PROTEIN EXPRESSION; TUMOR XENOGRAFT; ANIMAL; APOPTOSIS; C57BL MOUSE; CELL LINE; FLOW CYTOMETRY; GENE THERAPY; GENE VECTOR; GENETICS; GYROVIRUS; KIDNEY; LIVER TUMOR; METHODOLOGY; MORTALITY; PATHOLOGY; SURVIVAL RATE; TUMOR CELL LINE; WESTERN BLOTTING;

ANIMALS; APOPTOSIS; BLOTTING, WESTERN; CAPSID PROTEINS; CARCINOMA, HEPATOCELLULAR; CELL LINE; CELL LINE, TUMOR; CHICKEN ANEMIA VIRUS; FLOW CYTOMETRY; GENE THERAPY; GENETIC VECTORS; HUMANS; KIDNEY; LIVER NEOPLASMS, EXPERIMENTAL; MICE; MICE, INBRED C57BL; SURVIVAL RATE;

EID: 77951218981     PISSN: 00207136     EISSN: 10970215     Source Type: Journal    
DOI: 10.1002/ijc.24959     Document Type: Article

References (39)

1. Danen-Van Oorschot AA, Fischer DF, Grimbergen JM, Klein B, Zhuang S, Falkenburg JH, Backendorf C, Quax PH, Van der Eb AJ, Noteborn MH. Apoptin induces apoptosis in human transformed and malignant cells but not in normal cells. Proc Natl Acad Sci USA 1997;94:5843-5847 (Pubitemid 27241859)
2. Jeurissen SH, Wagenaar F, Pol JM, van der Eb AJ, Noteborn MH. Chicken anemia virus causes apoptosis of thymocytes after in vivo infection and of cell lines after in vitro infection. J Virol 1992;66:7383-7388
3. Rohn JL, Noteborn MH. The viral death effector apoptin reveals tumor-specific processes. Apoptosis 2004;9:315-322
4. Zhuang SM, Shvarts A, van Ormondt H, Jochemsen AG, van der Eb AJ, Noteborn MH. Apoptin, a protein derived from chicken anemia virus, induces p53-independent apoptosis in human osteosarcoma cells. Cancer Res 1995;55:486-489
5. Danen-van Oorschot AA, den Hollander AI, Takayama S, Reed JC, van der Eb AJ, Noteborn MH. BAG-1 inhibits p53-induced but not apoptin-induced apoptosis. Apoptosis 1997;2:395-402. (Pubitemid 127504723)
6. Danen-Van Oorschot AA, Zhang Y, Erkeland SJ, Fischer DF, van der Eb AJ, Noteborn MH. The effect of Bcl-2 on Apoptin in 'normal' vs transformed human cells. Leukemia 1999;13 (Suppl 1): S75-S77.
7. Burek M, Maddika S, Burek CJ, Daniel PT, Schulze-Osthoff K, Los M. Apoptininduced cell death is modulated by Bcl-2 family members and is Apaf-1 dependent. Oncogene 2006;25:2213-2222
8. Maddika S, Mendoza FJ, Hauff K, Zamzow CR, Paranjothy T, Los M. Cancer-selective therapy of the future: apoptin and its mechanism of action. Cancer Biol Ther 2006;5:10-19. (Pubitemid 43234971)
9. Pietersen AM, van der Eb MM, Rademaker HJ, van den Wollenberg DJ, Rabelink MJ, Kuppen PJ, van Dierendonck JH, van Ormondt H, Masman D, van de Velde CJ, van der Eb AJ, Hoeben RC, et al. Specific tumor-cell killing with adenovirus vectors containing the apoptin gene. Gene Ther 1999;6:882-892 (Pubitemid 29243663)
10. Li X, Jin N, Mi Z, Lian H, Sun L, Li X, Zheng H. Antitumor effects of a recombinant fowlpox virus expressing Apoptin in vivo and in vitro. Int J Cancer 2006;12:2948-2957 (Pubitemid 44846250)
11. Olijslagers S, Dege AY, Dinsart C, Voorhoeve M, Rommelaere J, Noteborn MH, Cornelis JJ. Potentiation of a recombinant oncolytic parvovirus by expression of Apoptin. Cancer Gene Ther 2001;8:958-965 (Pubitemid 33140314)
12. van der Eb MM, Pietersen AM, Speetjens FM, Kuppen PJ, van de Velde CJ, Noteborn MH, Hoeben RC. Gene therapy with apoptin induces regression of xenografted human hepatomas. Cancer Gene Ther 2002;9:53-61.
13. Hofmann C, Sandig V, Jennings G, Rudolph M, Schlag P, Strauss M. Efficient gene transfer into human hepatocytes by baculovirus vectors. Proc Natl Acad Sci USA 1995;92:10099-10103
14. Kost TA, Condreay JP. Recombinant baculoviruses as mammalian cell genedelivery vectors. Trends Biotechnol 2002;20:173-180 (Pubitemid 34242859)
15. Ho YC, Chen HC, Wang KC, Hu YC. Highly efficient baculovirus-mediated gene transfer into rat chondrocytes. Biotechnol Bioeng 2004;88:643-651
16. Sandig V, Hofmann C, Steinert S, Jennings G, Schlag P, Strauss M. Gene transfer into hepatocytes and human liver tissue by baculovirus vectors. Hum Gene Ther 1996;7:1937-1945 (Pubitemid 26390232)
17. Kim CH, Yoon JS, Sohn HJ, Kim CK, Paik SY, Hong YK, Kim TG. Direct vaccination with pseudotype baculovirus expressing murine telomerase induces anti-tumor immunity comparable with RNA-electroporated dendritic cells in a murine glioma model. Cancer Lett 2007;250:276-283
18. Song SU, Shin SH, Kim SK, Choi GS, Kim WC, Lee MH, Kim SJ, Kim IH, Choi MS, Hong YJ, Lee KH. Effective transduction of osteogenic sarcoma cells by a baculovirus vector. J Gen Virol 2003;84:697-703.
19. Pieroni L, Maione D, La Monica N. In vivo gene transfer in mouse skeletal muscle mediated by baculovirus vectors. Hum Gene Ther 2001;12:871-881
20. Tani H, Limn CK, Yap CC, Onishi M, Nozaki M, Nishimune Y, Okahashi N, Kitagawa Y, Watanabe R, Mochizuki R, Moriishi K, Matsuura Y. In vitro and in vivo gene delivery by recombinant baculoviruses. J Virol 2003;77:9799-9808
21. Barsoum J, Brown R, McKee M, Boyce FM. Efficient transduction of mammalian cells by a recombinant baculovirus having the vesicular stomatitis virus G glycoprotein. Hum Gene Ther 1997;8:2011-2018 (Pubitemid 28072572)
22. Hu YC. Baculoviral vectors for gene delivery: a review. Curr Gene Ther 2008;8:54-65. (Pubitemid 351485841)
23. Kost TA, Condreay JP, Jarvis DL. Baculovirus as versatile vectors for protein expression in insect and mammalian cells. Nat Biotechnol 2005;23:567-575 (Pubitemid 41724895)
24. Fan H, Pan Y, Fang L, Wang D, Wang S, Jiang Y, Chen H, Xiao S. Construction and immunogenicity of recombinant pseudotype baculovirus expressing the capsid protein of porcine circovirus type 2 in mice. J Virol Methods 2008;150:21-26
25. Facciabene A, Aurisicchio L, La Monica N. Baculovirus vectors elicit antigen-specific immune responses in mice. J Virol 2004;78:8663-8672 (Pubitemid 39025132)
26. Peng DJ, Sun J, Wang YZ, Tian J, Zhang YH, Noteborn MHM, Qu S. Inhibition of hepatocarcinoma by systemic delivery of Apoptin gene to the hepatic asiaglycorprotein receptor. Cancer Gene Ther 2007;14:66-73. (Pubitemid 44952235)
27. Strauss R, Huser A, Ni S, Tuve S, Kiviat N, Sow PS, Hofmann C, Lieber A. Baculovirus-based vaccination vectors allow for efficient induction of immune responses against plasmodium falciparum circumsporozoite protein. Mol Ther 2007;15:193-202. (Pubitemid 46043665)
28. Zender L, Kühnel F, Köck R, Manns M, Kubicka S. VP22-mediated intercellular transport of p53 in hepatoma cells in vitro and in vivo. Cancer Gene Ther 2002;9:489-496 (Pubitemid 34569031)
29. Danen-Van Oorschot AA, Zhang YH, Leliveld SR, Rohn JL, Seelen MC, Bolk MW, Van Zon A, Erkeland SJ, Abrahams JP, Mumberg D, Noteborn MH. Importance of nuclear localization of apoptin for tumor-specific induction of apoptosis. J Biol Chem 2003;278:27729-27736 (Pubitemid 36899962)
30. Heilman DW, Teodoro JG, Green MR. Apoptin nucleocytoplasmic shuttling is required for cell type-specific localization, apoptosis, and recruitment of the anaphase-promoting complex/cyclosome to PML bodies. J Virol 2006;80:7535-7545
31. Chada S, Ramesh R. Apoptin studies illuminate intersection between lipidomics and tumor suppressors. Mol Ther 2007;15:7-9. (Pubitemid 46043642)
32. Lee YH, Cheng CM, Chang YF, Wang TY, You CY. Apoptin 108 phosphorylation is not required for its tumor-specific nuclear localization but partially affects its apoptotic activity. Biochem Biophys Res Commun 2007;354:391-395
33. Poon IK, Oro C, Dias MM, Zhang JP, Jans DA. A tumor cell-specific nuclear targeting signal within chicken anemia virus VP3/apoptin. J Virol 2005;79:1339-1341 (Pubitemid 40053918)
34. Guelen B, Paterson H, Gaken J, Meyers M, Farzaneh F, Tavassoli M. TAT-apoptin is efficiently delivered and induces apoptosis in cancer cells. Oncogene 2004;23:1153-1165 (Pubitemid 38269969)
35. Shan L, Wang L, Yin J, Zhong P, Zhong J. An OriP/EBNA-1-based baculovirus vector with prolonged and enhanced transgene expression. J Gene Med 2006;8:1400-1406 (Pubitemid 46040647)
36. Wang CY, Wang S. Adeno-associated virus inverted terminal repeats improve neuronal transgene expression mediated by baculoviral vectors in rat brain. Hum Gene Ther 2005;16:1219-1226 (Pubitemid 41443714)
37. Park SW, Lee HK, Kim TG, Yoon SK, Paik SY. Hepatocyte-specific gene expression by baculovirus pseudotyped with vesicular stomatitis virus envelope glycoprotein. Biochem Biophys Res Commun 2001;289:444-450
38. Luz-Madrigal A, Clapp C, Aranda J, Vaca L. In vivo transcriptional targeting into the retinal vasculature using recombinant baculovirus carrying the human flt-1 promoter. Virol J 2007;4:88.
39. Wang CY, Li F, Yang Y, Guo HY, Wu CX, Wang S. Recombinant baculovirus containing the diphtheria toxin A gene for malignant glioma therapy. Cancer Res 2006;66:5798-5806 (Pubitemid 43927134)