Imaging of cell trafficking in Crohn's disease

Journal of Cellular Physiology

Volumn 223, Issue 3, 2010, Pages 562-571

  Glaudemans, Andor W J M ^a   Maccioni, Francesca ^b   Mansi, Luigi ^c   Dierckx, Rudi A J O ^a   Signore, Alberto ^a,b  

^a UNIVERSITY MEDICAL CENTER GRONINGEN   (Netherlands)

^b SAPIENZA UNIVERSITY OF ROME   (Italy)

^c SECOND UNIVERSITY OF NAPLES   (Italy)

Author keywords

[No Author keywords available]

Indexed keywords

8 QUINOLINOL INDIUM IN 111; ENDOTHELIAL LEUKOCYTE ADHESION MOLECULE 1; FLUORODEOXYGLUCOSE F 18; GADOLINIUM; GRANULOCYTE ANTIBODY; HEXAMETHYLPROPYLENE AMINE OXIME TECHNETIUM TC 99M; HUMAN IMMUNOGLOBULIN; INTERLEUKIN 2; INTERLEUKIN 8; MONOCLONAL ANTIBODY; RADIOPHARMACEUTICAL AGENT; TUMOR NECROSIS FACTOR ALPHA;

CELL MIGRATION; CONTRAST ENHANCEMENT; CROHN DISEASE; DIFFUSION WEIGHTED IMAGING; DISEASE ACTIVITY; FOLLOW UP; HUMAN; IMMUNE RESPONSE; LEUKOCYTE; MOLECULAR IMAGING; NON INVASIVE PROCEDURE; NONHUMAN; NUCLEAR MAGNETIC RESONANCE IMAGING; NUCLEAR MAGNETIC RESONANCE SPECTROSCOPY; NUCLEAR MEDICINE; PATHOGENESIS; PRIORITY JOURNAL; REVIEW; SCINTIGRAPHY; SMALL INTESTINE; ULCERATIVE COLITIS; ANIMAL; CELL MOTION; DIAGNOSTIC IMAGING; IMMUNOLOGY; INFLAMMATION; METHODOLOGY; PATHOLOGY; POSITRON EMISSION TOMOGRAPHY; RADIOGRAPHY;

ANIMALS; CELL MOVEMENT; CROHN DISEASE; DIAGNOSTIC IMAGING; HUMANS; INFLAMMATION; POSITRON-EMISSION TOMOGRAPHY;

EID: 77951218090     PISSN: 00219541     EISSN: 10974652     Source Type: Journal    
DOI: 10.1002/jcp.22069     Document Type: Review

References (76)

1. Aime S, Cabella C, Colombatto S, Geninatti Crich S,Gianolio E, Maggioni F. 2002. Insights into the use of aramagnetic Gd(III) complexes in MR-molecular imaging investigations. J Magn Reson Imaging 16:394-406.
2. Ajaj WM, Lauenstein TC, Pelster G, Gerken G, Ruehm SG, Debatin JF, Goehde SC. 2005. Magnetic resonance colonography for the detection of inflammatory diseases of the large bowel: Quantifying the inflammatory activity. Gut 54:257-263. (Pubitemid 40139243)
3. Alberini JL, Badran A, Freneaux E, Hadji S, Kalifa G, Devaux JY, Dupont T. 2001. Technetium-99m HMPAO-labeled leukocyte imaging compared with endoscopy, ultrasonography, and contrast radiology in children with inflammatory bowel disease. J Pediatr Gastroenterol Nutr 32:278-286. (Pubitemid 32374305)
4. Andres PG, Friedman LS. 1999. Epidemiology and the natural course of inflammatory bowel disease. Gastroenterol Clin North Am 28:255-281, vii.
5. Annovazzi A, Biancone L, Caviglia R, Chianelli M, Capriotti G, Mather SJ, Caprilli R, Pallone F, Scopinaro F, Signore A. 2003. 99mTc-interleukin-2 and (99m)Tc-HMPAO granulocyte scintigraphy in patients with inactive Crohn's disease. Eur J Nucl Med Mol Imaging 30:374-382.
6. Arndt JW, Sluys Veer A, Blok D, Griffioen G, Verspaget HW, Pena AS, Lamers CB, Pauwels EK. 1992. A prospective comparison of 99mTc-labeled polyclonal human immunoglobulin and 111In granulocytes for localization of inflammatory bowel disease. Acta Radiol 33:140-144.
7. Arndt JW, Sluys Veer A, Blok D, Griffoen G, Verspaget HW, Lamers CB, Pauwels EK. 1993. Prospective comparative study of technetium-99m-WBCs and indium-111-granulocytes for the examination of patients with inflammatory bowel disease. J Nucl Med 34:1052-1057. (Pubitemid 23191318)
8. Arndt JW, Grootscholten MI, van Hogezand RA, Griffioen G, Lamers CB, Pauwels EK. 1997. Inflammatory bowel disease activity assessment using technetium-99m-HMPAO leukocytes. Dig Dis Sci 42:387-393. (Pubitemid 27112988)
9. Aydin F, Dincer D, Gungor F, Boz A, Akca S, Yildiz A, Tosun O, Karayalcin B. 2008. Technetium-99m hexamethyl propylene amine oxime-labeled leukocyte scintigraphy at three different times in active ulcerative colitis: Comparisonwith colonoscopy and clinicobiochemical parameters in the assessment of disease extension and severity. Ann Nucl Med 22:371-377.
10. Bhatti M, Chapman P, Peters M, Haskard D, Hodgson HJ. 1998. Visualising E-selectin in the detection and evaluation of inflammatory bowel disease. Gut 43:40-47.
11. Biancone L, Scopinaro F, Ierardi M, Paoluzi P, Marcheggiano A, Di Paolo MC, Porowska B, Colella AC, Pallone F. 1997. 99mTc-HMPAO granulocyte scintigraphy in the early detection of postoperative asymptomatic recurrence in Crohn's disease. Dig Dis Sci 42:1549-1556.
12. Biancone L, Schillaci O, Capoccetti F, Bozzi RM, Fina D, Petruzziello C, Geremia A, Simonetti G, Pallone F. 2005. Technetium-99m-HMPAO labeled leukocyte single photon emission computerized tomography (SPECT) for assessing Crohn's disease extent and intestinal infiltration. Am J Gastroenterol 100:344-354.
13. Bruno I, Martelossi S, Geatti O, Maggiore G, Guastalla P, Povolato M, Ventura A. 2002. Antigranulocyte monoclonal antibody immunoscintigraphy in inflammatory bowel disease in children and young adolescents. Acta Paediatr 91:1050-1055.
14. Buscombe JR, Lui D, Ensing G, de Jong R, Ell PJ. 1990. 99mTc-human immunoglobulin (HIG)- First results of a new agent for the localization of infection and inflammation. Eur J Nucl Med 16:649-655.
15. Cassidy PJ, Radda GK. 2005. Molecular imaging perspectives. Review. J R Soc Interface 2:133-144.
16. Charron M. 2003. Inflammatory bowel disease activity assessment with biologic markers and 99mTc-WBC scintigraphy: Are there different trends in ileitis versus colitis? J Nucl Med 44:1586-1591.
17. Charron M, Di Lorenzo C, Kocoshis SA, Hickeson MP, Orenstein SR, Goyal A, Kahn S, Collins L. 2001. (99m)Tc antigranulocyte monoclonal antibody imaging for the detection and assessment of inflammatory bowel disease newly diagnosed by colonoscopy in children. Pediatr Radiol 31:796-800.
18. Choi D, Jin Lee S, Ah Cho Y, et al. 2003. Bowel wall thickening in patients with Crohn's disease: CT patterns and correlation with inflammatory activity. Clin Radiol 58:68-74.
19. D'Alessandria C, Malviya G, Viscido A, Aratari A, Maccioni F, Amato A, Scopinaro F, Caprilli R, Signore A. 2007. Use of a 99mTc labeled anti-TNFalpha monoclonal antibody in Crohn's disease: In vitro and in vivo studies. Q J Nucl Med Mol Imaging 51:334-342.
20. Delgado Castro M, Lancha C, Prats E, Mitjavilla M, Abos D, Martin-Curto LM, Crespo A, Banzo J. 1997. The diagnostic value of Tc-99m human polyclonal immunoglobulin imaging compared to Tc-99m HMPAO labeled leukocytes in inflammatory bowel disease. Clin Nucl Med 22:17-20.
21. Esteban JM, Maldonado L, Sanchiz V, Minguez M, Benages A. 2001. Activity of Crohn's disease assessed by colour Doppler ultrasound analysis of the affected loops. Eur Radiol 11:1423-1428.
22. Fidler J. 2007. MR imaging of the small bowel. Radiol Clin N Am 45:317-331.
23. Fiocchi C. 1998. Inflammatory bowel disease: Etiology and pathogenesis. Gastroenterology 115:182-205.
24. Fischman AJ, Rubin RH, Khaw BA, Callahan RJ, Wilkinson R, Keech F, Nedelman M, Dragotakes S, Kramer PB, La Muraglia GM. 1988. Detection of acute inflammation with 111In-labeled nonspecific polyclonal Ig G. Semin Nucl Med 18:335-344.
25. Florie J, Wasser MNJ, Arts-Cieslik K, et al. 2006. Dynamic contrast-enhanced MRI of the bowel wall for assessment of disease activity in Crohn's disease. AJR Am J Roentgenol 186:1384-1392.
26. Froelich JW, Field SA. 1988. The role of indium-111 white blood cells in inflammatory bowel disease. Semin Nucl Med 18:300-307.
27. Golder W. 2007. Magnetic resonance spectroscopy in clinical oncology. Onkologie 27:304-309.
28. Gourtsoyiannis N, Papanikolaou N, Grammatikakis J, et al. 2004. Assessment of Crohn's disease activity in the small bowel with MR and conventional enteroclysis: Preliminary results. Eur Radiol 14:1017-1024.
29. Gourtsoyiannis N, Papanikolau N, Grammatikakis J, Prassopoulus P. 2002. MR enteroclisys: Technical considerations and clinical applications. Eur Radiol 12:2651-2658. (Pubitemid 36940374)
30. Gratz S, Rennen HJ, Boerman OC, Oyen WJ, Corstens FH. 2001. Rapid imaging of experimental colitis with (99m)Tc-interleukin-8 in rabbits. J Nucl Med 42:917-923.
31. Gyorke T, Duffek L, Bartfai K, Mako E, Karlinger K, Mester A, Tarjan Z. 2000. The role of nuclear medicine in inflammatory bowel disease. A review with experiences of aspecific bowel activity using immunoscintigraphy with 99mTc anti-granulocyte antibodies. Eur J Radiol 35:183-192.
32. Hanauer SB. 2006. Inflammatory bowel disease: Epidemiology, pathogenesis, and therapeutic opportunities. Inflamm Bowel Dis 12:S3-S9.
33. Hebbard GS, Salehi N, Gibson PR, Lichtenstein M, Andrews JT. 1992. 99Tcm-labelled IgG scanning does not predict the distribution of intestinal inflammation in patients with inflammatory bowel disease. Nucl Med Commun 13:336-341.
34. Jamar F, Houssiau FA, Devogelaer JP, Chapman PT, Haskard DO, Beaujean V, Beckers C, Manicourt DH, Peters AM. 2002. Scintigraphy using a technetium 99m-labelled anti-Eselectin Fab fragment in rheumatoid arthritis. Rheumatology (Oxford) 41:53-61.
35. Jasper F, Wasser MN, Arts-Geslik K, et al. 2006. Dynamic contrast-enhanced MRI of the bowel wall for assessment of disease activity in Crohn's disease. Am J Radiol 186:1384-1392.
36. Kerry JE, Marshall C, Griffiths PA, Scott BB, Griffiths G. 2003. White cell scanning for inflammatory bowel disease: Are biochemical markers useful referral criteria? Nucl Med Commun 24:1145-1148.
37. Kerry JE, Marshall C, Griffiths PA, James MW, Scott BB. 2005. Comparison between Tc-HMPAO labelled white cells and Tc Leuko Scan in the investigation of inflammatory bowel disease. Nucl Med Commun 26:245-251.
38. Kiryu S, Dodanuki K, Takao H, et al. 2009. Free-breathing diffusion-weighted imaging for the assessment of inflammatory activity in Crohn's disease. J Magn Reson Imaging 29:880-886.
39. Koh DM, Miao Y, Chinn RJ, Amin Z, et al. 2001. MR imaging avaluation of the activity of Crohn's disease. Am J Roentgenol 177:1325-1332.
40. Koizumi M, King N, Lobb R, Benjamin C, Podolsky DK. 1992. Expression of vascular adhesion molecules in inflammatory bowel disease. Gastroenterology 103:840-847.
41. Laghi A, Borrelli O, Paolantonio P, et al. 2003. Contast enhanced magnetic resonance imaging of the terminal ileum in children with Crohn's disease. Gut 52:393-397, 17
42. Li DJ, Middleton SJ, Wraight EP. 1992. 99Tcm and 111In leucocyte scintigraphy in inflammatory bowel disease. Nucl Med Commun 13:867-870.
43. Loffler M, Weckesser M, Franzius C, Schober O, Zimmer KP. 2006. High diagnostic value of 18F-FDG-PET in pediatric patients with chronic inflammatory bowel disease. Ann N Y Acad Sci 1072:379-385.
44. Loftus EV, Jr. 2004. Clinical epidemiology of inflammatory bowel disease: Incidence, prevalence, and environmental influences. Gastroenterology 126:1504-1517.
45. Louis E, Belaiche J, Van Kemseke C, Schaaf N, Mahieu P, Mary JY. 1995. Soluble interleukin-2 receptor in Crohn's disease. Assessment of disease activity and prediction of relapse. Dig Dis Sci 40:1750-1756.
46. Louis E, Ancion G, Colard A, Spote V, Belaiche J, Hustinx R. 2007. Noninvasive assessment of Crohn's disease intestinal lesions with (18)F-FDG PET/CT. J Nucl Med 48:1053-1059.
47. Low RN, Sebrechts CP, Politoske DA, et al. 2002. Crohn disease with endoscopic and gadolinium-enhanced fat-suppressed spoiled gradient-echo MR imaging. Radiology 222:652-660.
48. Maccioni F. 2008. Double contrast MRI of the small and large bowel: Effectiveness in the evaluation of inflammatory bowel disease. Abdom Imaging. [Epub ahead of print]
49. Maccioni F, Viscido A, Broglia L, et al. 2000. Evaluation of Crohn's disease activity with MRI. Abdom Imaging 25: 219-228.
50. Maccioni F, Viscido A, Broglia L, et al. 2000. Evaluation of Crohn's disease activity with MRI. Abdom Imaging 25:219-228.
51. Maccioni F, Bruni A, Viscido A, Colaiacomo MC, Cocco A, Montesani C, Caprilli R, Marini M. 2005a. MR imaging in patients with Crohn disease: Value of T2- versus T1-weighted gadolinium-enhanced MR sequences with use of an oral superparamagnetic contrast agent. Radiology 238:517-530.
52. Maccioni F, Colaiacomo MC, Parlanti S. 2005b. Ulcerative colitis: Value of MR imaging. Abdom Imaging 30:584-592 (review).
53. Mac Kalski BA, Bernstein CN. 2006. New diagnostic imaging tools for inflammatory bowel disease. Gut 55:733-741.
54. Mairal L, de Lima PA, Martin-Comin J, Baliellas C, Xiol X, Roca M, Ricart Y, Ramos M. 1995. Simultaneous administration of 111In-human immunoglobulin and 99mTc-HMPAO labelled leucocytes in inflammatory bowel disease. Eur J Nucl Med 22:664-670.
55. Meisner RS, Spier BJ, Einarsson S, Roberson EN, Perlman SB, Bianco JA, Taylor AJ, Einstein M, Jaskowiak CJ, Massoth KM, Reichelderfer M. 2007. Pilot study using PET/CT as a novel, noninvasive assessment of disease activity in inflammatory bowel disease. Inflamm Bowel Dis 13:993-1000.
56. Molnar T, Papos M, Gyulai C, Ambrus E, Kardos L, Nagy F, Palko A, Pavics L, Lonovics J. 2001. Clinical value of technetium-99m-HMPAO-labeled leukocyte scintigraphy and spiral computed tomography in active Crohn's disease. Am J Gastroenterol 96:1517-1521.
57. Murata Y, Ishiguro Y, Itoh J, Munakata A, Yoshida Y. 1995. The role of proinflammatory and immunoregulatory cytokines in the pathogenesis of ulcerative colitis. J Gastroenterol 30:56-60.
58. Neurath MF, Vehling D, Schunk K, Holtmann M, Brockmann H, Helisch A, Orth T, Schreckenberger M, Galle PR, Bartenstein P. 2002. Noninvasive assessment of Crohn's disease activity: A comparison of 18F-fluorodeoxyglucose positron emission tomography, hydromagnetic resonance imaging, and granulocyte scintigraphy with labeled antibodies. Am J Gastroenterol 97:1978-1985.
59. Olejniczak K, Kasprzak A. 2008. Biological properties of interleukin 2 and its role in pathogenesis of selected diseases-A review. Med Sci Monit 14:RA179-RA189.
60. Oyen WJ, Claessens RA, van der Meer JW, Rubin RH, Strauss HW, Corstens FH. 1992. Indium-111-labeled human nonspecific immunoglobulin G: A new radiopharmaceutical for imaging infectious and inflammatory foci. Clin Infect Dis 14:1110-1118.
61. Papos M, Nagy F, Lang J, Csernay L. 1993. Technetium-99m hexamethylpropylene amine oxime labelled leucocyte scintigraphy in ulcerative colitis and Crohn's disease. Eur J Nucl Med 20:766-769.
62. Papos M, Nagy F, Narai G, Rajtar M, Szantai G, Lang J, Csernay L. 1996. Anti-granulocyte immunoscintigraphy and [99mTc]hexamethylpropyleneamine-oxime- labeled leukocyte scintigraphy in inflammatory bowel disease. Dig Dis Sci 41:412-420.
63. Podolsky DK. 2002. Inflammatory bowel disease. N Engl J Med 347:417-429.
64. Potter K. 2002. Magnetic resonancemicroscopy approaches to molecular imaging: Sensitivity vs. specificity. J Cell Biochem Suppl 39:147-153.
65. Rimola J, Rodriguez S, Garcia-Bosch O, et al. 2009. Magnetic resonance for assessment of disease activity and severity in ileocolonic Crohn's disease. Gut 58:1113-1120.
66. Rosen Y. 2007. The Recent advances in magnetic resonance neurospectroscopy. Neurotherapeutics 27:330-345.
67. Sachar DB, Luppescu NE, Bodian C, Shlien RD, Fabry TL, Gumaste VV. 1990. Erythrocyte sedimentation as a measure of Crohn's disease activity: Opposite trends in ileitis versus colitis. J Clin Gastroenterol 12:643-646.
68. Saverymuttu SH, Peters AM, Lavender JP, Pepys MB, Hodgson HJ, Chadwick VS. 1983. Quantitative fecal indium 111-labeled leukocyte excretion in the assessment of disease in Crohn's disease. Gastroenterology 85:1333-1339.
69. Sciarretta G, Furno A, Mazzoni M, Basile C, Malaguti P. 1993. Technetium-99m hexamethyl propylene amine oxime granulocyte scintigraphy in Crohn's disease:Diagnostic and clinical relevance. Gut 34:1364-1369.
70. Sempere GAJ, Sanjuan VM, Chulia EM, et al. MRI evaluation of inflammatory activity in CD. AJR Am J Roentgenol 2005. 184:1829-1835.
71. Signore A, Chianelli M, Annovazzi A, Bonanno E, Spagnoli LG, Pozzilli P, Pallone F, Biancone L. 2000. 123I-interleukin-2 scintigraphy for in vivo assessment of intestinal mononuclear cell infiltration in Crohn's disease. J Nucl Med 41:242-249.
72. Spier BJ, Perlman SB, Jaskowiak CJ, Reichelderfer M. 2010. PET/CT in the evaluation of inflammatory bowel disease: Studies in patients before and after treatment. Mol Imaging Biol 12:85-88.
73. Stathaki MI, Koutroubakis IE, Koukouraki SI, Karmiris KP, Moschandreas JA, Kouroumalis EA, Karkavitsas NS. 2008. Active inflammatory bowel disease: Head-to-head comparison between 99mTc-hexamethylpropylene amine oxime white blood cells and 99mTc(V)-dimercaptosuccinic acid scintigraphy. Nucl Med Commun 29:27-32.
74. Stokkel MP, Reigman HE, Pauwels EK. 2002. Scintigraphic head-to-head comparison between 99mTc-WBCs and 99mTc-Leuko Scan in the evaluation of inflammatory bowel disease: A pilot study. Eur J Nucl Med Mol Imaging 29:251-254.
75. Versaci A, Bonanno N, Baldari S, Terranova M, Macri A, Leonello G, Famulari C. 1999. Diagnostic possibilities and clinical indications of policlonal labeled Ig in the bowel inflammatory disease. Hepatogastroenterology 46:2260-2264.
76. Xavier RJ, Podolsky DK. 2007. Unravelling the pathogenesis of inflammatory bowel disease. Nature 448:427-434.