Link between Pericardial Effusion and Attenuation of QRS Voltage in Patients with Hypothyroidism

Cardiology

Volumn 116, Issue 1, 2010, Pages 32-36

  Yamanaka, Shigeo ^a   Kumon, Yoshitaka ^a   Matsumura, Yoshihisa ^a   Kamioka, Mikio ^a   Takeuchi, Hiroaki ^a   Sugiura, Tetsuro ^a  

^a KOCHI MEDICAL SCHOOL   (Japan)

Author keywords

Echocardiography; Hypothyroidism; Low voltage electrocardiogram; Pericardial effusion

Indexed keywords

ALBUMIN; THYROID HORMONE; THYROXINE;

ADULT; AGED; ARTICLE; BLOOD EXAMINATION; CONTROLLED STUDY; DISEASE SEVERITY; ECHOCARDIOGRAPHY; ELECTROCARDIOGRAM; ELECTROCARDIOGRAPHY; FEMALE; HORMONE DEFICIENCY; HUMAN; HYPOTHYROIDISM; LUNG ARTERY PRESSURE; MAJOR CLINICAL STUDY; MALE; ONCOTIC PRESSURE; PERICARDIAL EFFUSION; PRIORITY JOURNAL; QRS COMPLEX; SYSTOLIC BLOOD PRESSURE; THYROID FUNCTION TEST;

AGED; AGED, 80 AND OVER; ECHOCARDIOGRAPHY; ELECTROCARDIOGRAPHY; FEMALE; HUMANS; HYPOTHYROIDISM; MALE; MIDDLE AGED; MULTIVARIATE ANALYSIS; OSMOTIC PRESSURE; PERICARDIAL EFFUSION; PULMONARY WEDGE PRESSURE; SERUM ALBUMIN; THYROXINE; WATER-ELECTROLYTE IMBALANCE;

EID: 77951215071     PISSN: 00086312     EISSN: None     Source Type: Journal    
DOI: 10.1159/000313464     Document Type: Article

References (29)

1. Kerber RE, Sherman B: Echocardiographic evaluation of pericardial effusion in myxedema. Incidence and biochemical and clinical correlations. Circulation 1975; 52: 823-827.
2. Tajiri J, Morita M, Higashi K, Fujii H, Nakamura N, Sato T: The cause of low voltage QRS complex in primary hypothyroidism. Pericardial effusion or thyroid hormone deficiency? Jpn Heart J 1985; 26: 539-547.
3. Kabadi UM, Kummar SP: Pericardial effusion in primary hypothyroidism. Am Heart J 1990; 120: 1393-1395.
4. Spodick DH: The Pericardium. A Comprehensive Textbook. New York, Marcel Dekker, 1997, pp 291-300.
5. Klein I, Danzi S: Thyroid disease and the heart. Circulation 2007; 116: 1725-1735.
6. Unverferth DV, Williams TE, Fulkerson PK: Electrocardiographic voltage in pericardial effusion. Chest 1979; 75: 157-160.
7. Meyers DG, Bagin RG, Levene JF: Electrocardiographic changes in pericardial effusion. Chest 1993; 104: 1422-1426.
8. Eisenberg MJ, de Romeral LM, Heidenreich PA, Schiller NB, Evans T Jr: The diagnosis of pericardial effusion and cardiac tamponade by 12-lead ECG. A technology assessment. Chest 1996; 110: 318-324.
9. Kudo Y, Yamasaki F, Doi T, Doi Y, Sugiura T: Clinical significance of low voltage in asymptomatic patients with pericardial effusion free of heart disease. Chest 2003; 124: 2064-2067.
10. Henry WL, Gardin JM, Ware JH: Echocardiographic measurements in normal subjects from infancy to old age. Circulation 1980; 62: 1054-1060.
11. Currie PJ, Seward JB, Chan KL, Fyfe DA, Hagler DJ, Mair DD, Reeder GS, Nishimura RA, Tajik AJ: Continuous wave Doppler determination of right ventricular pressure: a simultaneous Doppler-catheterization study in 127 patients. J Am Coll Cardiol 1985; 6: 750-756.
12. Horowitz MS, Schultz CS, Stinson EB, Harrison DC, Popp RL: Sensitivity and specificity of echocardiographic diagnosis of pericardial effusion. Circulation 1974; 50: 239-247.
13. Weitzman LB, Tinker WP, Kronzon I, Cohen ML, Glassman E, Spencer FC: The incidence and natural history of pericardial effusion after cardiac surgery. An echocardiographic study. Circulation 1984; 69: 506-511.
14. Spodick DH: The normal and diseased pericardium: current concepts of pericardial physiology, diagnosis and treatment. J Am Coll Cardiol 1983; 1: 240-251.
15. Kudo Y, Yamasaki F, Doi Y, Sugiura T: Clinical correlates of PR-segment depression in asymptomatic patients with pericardial effusion. J Am Coll Cardiol 2002; 39: 2000-2004.
16. Parving HH, Hansen JM, Nielsen SL, Rossing N, Munck O, Lassen NA: Mechanisms of edema formation in myxedema-increased protein extravasation and relatively slow lymphatic drainage. N Engl J Med 1979; 301: 460-465.
17. Badesch DB, Wynne KM, Bonvallet S, Voelkel NF, Ridgway C, Groves BM: Hypothyroidism and primary pulmonary hypertension: an autoimmune pathogenetic link? Ann Intern Med 1993; 119: 44-46.
18. Curnock AL, Dweik RA, Higgins BH, Saadi HF, Arroliga AC: High prevalence of hypothyroidism in patients with primary pulmonary hypertension. Am J Med Sci 1999; 318: 289-292.
19. Chu JW, Kao PN, Faul JL, Doyle RL: High prevalence of autoimmume thyroid disease in pulmonary arterial hypertension. Chest 2002; 122: 1668-1673.
20. Zwillich CW, Pierson DJ, Hofeldt FD, Lufkin E, Weil JV: Ventilatory control in myxedema and hypothyroidism. N Engl J Med 1975; 292: 662-665.
21. Miller AJ, Pick R, Johnson PJ: The production of acute pericardial effusion: the effects of various degrees of interference with venous blood and lymph drainage from the heart muscle in the dog. Am J Cardiol 1971; 28: 463-466.
22. Rushmer RF: Functional anatomy and control of the heart; in Rushmer RF (ed): Cardiovascular Dynamics, ed 4. Philadelphia, WB Saunders, 1976, pp 89-99.
23. Talbot S, Kilpatrick D, Jonathan A, Raphael MJ: QRS voltage of the electrocardiogram and Frank vectorcardiogram in relation to ventricular volume. Br Heart J 1977; 39: 1109-1113.
24. Rudy Y, Plonsey R, Liebman J: The effects of variation in conductivity and geometrical parameters on the electrocardiogram, using an eccentric spheres model. Circ Res 1979; 44: 104-111.
25. Madias JE, Bazaz R, Agarwal H, Win M, Medepalli L: Anasarca-mediated attenuation of the amplitude of electrocardiogram complexes: a description of a heretofore unrecognized phenomenon. J Am Coll Cardiol 2001; 38: 756-764.
26. Bruch C, Schmermund A, Dagres N, Bartel T, Caspari G, Sack S, Erbel R: Changes in QRS voltage in cardiac tamponade and pericardial effusion: reversibility after pericardiocentesis and after anti-inflammatory drug treatment. J Am Coll Cardiol 2001; 38: 219-226.
27. Heaf JG: Albumin-induced changes in the electrocardiographic QRS complex. Am J Cardiol 1985; 55: 1530-1533.
28. Kudo Y, Yamasaki F, Kataoka H, Doi Y, Sugiura T: Effect of serum albumin on QRS wave amplitude in patients free of heart disease. Am J Cardiol 2005; 95: 789-791.
29. Madias JE: Low voltage ECG in myocarditis: peripheral edema as a plausible contributing mechanism. Pacing Clin Electrophysiol 2007; 30: 448-452.