메뉴 건너뛰기




Volumn 10, Issue 4, 2010, Pages 541-548

Role of capecitabine and irinotecan combination therapy in advanced or metastatic gastric cancer

Author keywords

Advanced; Capecitabine; Combination; Gastric cancer; Irinotecan; Metastatic

Indexed keywords

BEVACIZUMAB; CAPECITABINE; CETUXIMAB; CISPLATIN; EPIRUBICIN; FLUOROPYRIMIDINE; FLUOROURACIL; GEFITINIB; IMATINIB; IRINOTECAN; OXALIPLATIN; TRASTUZUMAB;

EID: 77951213495     PISSN: 14737140     EISSN: 17448328     Source Type: Journal    
DOI: 10.1586/era.09.179     Document Type: Review
Times cited : (9)

References (65)
  • 1
    • 12944315569 scopus 로고    scopus 로고
    • GLOBOCAN 2002 cancer incidence, mortality and prevalence worldwide
    • version 2.0, IARC Press, Lyon, France
    • Ferlay J, Bray F, Pisani P, Parkin DM. GLOBOCAN 2002 cancer incidence, mortality and prevalence worldwide. IARC Cancerbase no. 5, version 2.0, IARC Press, Lyon, France (2004).
    • (2004) IARC Cancerbase No. 5
    • Ferlay, J.1    Bray, F.2    Pisani, P.3    Parkin, D.M.4
  • 3
    • 48049120646 scopus 로고    scopus 로고
    • Geographic differences in gastric cancer incidence can be explained by differences between Helicobacter pylori strains
    • Yamaoka Y, Kato M, Asaka M. Geographic differences in gastric cancer incidence can be explained by differences between Helicobacter pylori strains. Intern. Med. 47(12), 1077-1083 (2008).
    • (2008) Intern. Med. , vol.47 , Issue.12 , pp. 1077-1083
    • Yamaoka, Y.1    Kato, M.2    Asaka, M.3
  • 5
    • 0028018308 scopus 로고
    • Gastric cancer
    • Correa P, Chen VW. Gastric cancer. Cancer Surv. 19-20, 55-76 (1994). (Pubitemid 24289379)
    • (1994) Cancer Surveys , vol.19-20 , pp. 55-76
    • Correa, P.1    Chen, V.W.2
  • 6
    • 0030981560 scopus 로고    scopus 로고
    • Gastric cancer in the European Union (1968-1992): Mortality trends and cohort effect
    • DOI 10.1016/S1047-2797(97)00002-1, PII S1047279797000021
    • Aragonés N, Pollán M, Rodero I, López-Abente G. Gastric cancer in the European Union (1968-1992): mortality trends and cohort effect. Ann. Epidemiol. 7(4), 294-303 (1997). (Pubitemid 27248653)
    • (1997) Annals of Epidemiology , vol.7 , Issue.4 , pp. 294-303
    • Aragones, N.1    Pollan, M.2    Rodero, I.3    Lopez-Abente, G.4
  • 7
    • 0038394851 scopus 로고    scopus 로고
    • World Health Organization International Agency for Research on Cancer
    • Stewart BW, Kleihues P. World Health Organization International Agency for Research on Cancer. World Cancer Report (2003).
    • (2003) World Cancer Report
    • Stewart, B.W.1    Kleihues, P.2
  • 8
    • 33646568784 scopus 로고    scopus 로고
    • Patterns of cancer incidence, mortality, and prevalence across five continents: Defining priorities to reduce cancer disparities in different geographic regions of the world
    • DOI 10.1200/JCO.2005.05.2308
    • Kamangar F, Dores GM, Anderson WF. Patterns of cancer incidence, mortality, and prevalence across five continents: defining priorities to reduce cancer disparities in different geographic regions of the world. J. Clin. Oncol. 24(14), 2137-2150 (2006). (Pubitemid 46655601)
    • (2006) Journal of Clinical Oncology , vol.24 , Issue.14 , pp. 2137-2150
    • Kamangar, F.1    Dores, G.M.2    Anderson, W.F.3
  • 12
    • 0032523070 scopus 로고    scopus 로고
    • Treatment of patients with advanced gastric carcinoma with a 5- fluorouracil-based or a cisplatin-based regimen: Two parallel randomized phase II studies
    • DOI 10.1002/(SICI)1097-0142(19980415)82:8<1460::AID-CNCR5>3.0.CO;2- D
    • Barone C, Corsi DC, Pozzo C et al. Treatment of patients with advanced gastric carcinoma with a 5-fluorouracil-based or a cisplatin based regimen: two parallel randomized Phase II studies. Cancer 82, 1460-1467 (1998). (Pubitemid 28164990)
    • (1998) Cancer , vol.82 , Issue.8 , pp. 1460-1467
    • Barone, C.1    Corsi, D.C.2    Pozzo, C.3    Cassano, A.4    Fontana, T.5    Noviello, M.R.6    Landriscina, M.7    Colloca, G.8    Astone, A.9
  • 16
    • 0037265616 scopus 로고    scopus 로고
    • A pilot phase II study of capecitabine in advanced or recurrent gastric cancer
    • DOI 10.1159/000069313
    • Koizumi W, Saigenji K, Ujiie S, Terashima M, Sakata Y, Taguchi T. A pilot Phase II study of capecitabine in advanced or recurrent gastric cancer. Oncology 64, 232-236 (2003). (Pubitemid 36438808)
    • (2003) Oncology , vol.64 , Issue.3 , pp. 232-236
    • Koizumi, W.1    Saigenji, K.2    Ujiie, S.3    Terashima, M.4    Sakata, Y.5    Taguchi, T.6
  • 19
    • 33646591539 scopus 로고    scopus 로고
    • Disparities in gastric cancer chemotherapy between the east and west
    • DOI 10.1200/JCO.2006.05.9758
    • Ohtsu A, Yoshida S, Saijo N. Disparities in gastric cancer chemotherapy between the East and West. J. Clin. Oncol. 24, 2188-2196 (2006). (Pubitemid 46630691)
    • (2006) Journal of Clinical Oncology , vol.24 , Issue.14 , pp. 2188-2196
    • Ohtsu, A.1    Yoshida, S.2    Saijo, N.3
  • 21
    • 34648843716 scopus 로고    scopus 로고
    • The UK NCRI MAGIC trial of perioperative chemotherapy in resectable gastric cancer: Implications for clinical practice
    • DOI 10.1245/s10434-007-9423-7
    • Chua YJ, Cunningham D. The UK NCRI MAGIC trial of perioperative chemotherapy in resectable gastric cancer: implications for clinical practice. Ann. Surg. Oncol. 14(10), 2687-2690 (2007). (Pubitemid 47460625)
    • (2007) Annals of Surgical Oncology , vol.14 , Issue.10 , pp. 2687-2690
    • Chua, Y.J.1    Cunningham, D.2
  • 22
    • 14644424630 scopus 로고    scopus 로고
    • Available options in chemotherapy for advanced gastric cancer: The current developments in Japan
    • DOI 10.1517/14656566.6.2.225
    • Koizumi W. Available options in chemotherapy for advanced gastric cancer: the current developments in Japan. Expert Opin. Pharmacother. 6(2), 225-231 (2005). (Pubitemid 40309125)
    • (2005) Expert Opinion on Pharmacotherapy , vol.6 , Issue.2 , pp. 225-231
    • Koizumi, W.1
  • 24
    • 43249095213 scopus 로고    scopus 로고
    • Chemotherapy for metastatic gastric cancer: Past, present, and future
    • DOI 10.1007/s00535-008-2177-6
    • Ohtsu A. Chemotherapy for metastatic gastric cancer: past, present, and future. J. Gastroenterol. 43(4), 256-264 (2008). (Pubitemid 351650035)
    • (2008) Journal of Gastroenterology , vol.43 , Issue.4 , pp. 256-264
    • Ohtsu, A.1
  • 28
    • 0032127244 scopus 로고    scopus 로고
    • Design of a novel oral fluoropyrimidine carbamate, capecitabine, which generates 5 fluorouracil selectively in tumours by enzymes concentrated in human liver and cancer tissue
    • DOI 10.1016/S0959-8049(98)00058-6, PII S0959804998000586
    • Miwa M, Ura M, Nishida M et al. Design of a novel oral fluoropyrimidine carbamate, capecitabine, which generates 5-fluorouracil selectively in tumours by enzymes concentrated in human liver and cancer tissue. Eur. J. Cancer 34, 1274-1281 (1998). (Pubitemid 28342121)
    • (1998) European Journal of Cancer , vol.34 , Issue.8 , pp. 1274-1281
    • Miwa, M.1    Ura, M.2    Nishida, M.3    Sawada, N.4    Ishikawa, T.5    Mori, K.6    Shimma, N.7    Umeda, I.8    Ishitsuka, H.9
  • 31
    • 33646255671 scopus 로고    scopus 로고
    • Phase II study of a 4-week capecitabine regimen in advanced or recurrent gastric cancer
    • Clinical Study Group of Capecitabine
    • Sakamoto J, Chin K, Kondo K et al.; Clinical Study Group of Capecitabine. Phase II study of a 4-week capecitabine regimen in advanced or recurrent gastric cancer. Anticancer Drugs 17(2), 231-236 (2006).
    • (2006) Anticancer Drugs , vol.17 , Issue.2 , pp. 231-236
    • Sakamoto, J.1    Chin, K.2    Kondo, K.3
  • 32
    • 49549119361 scopus 로고    scopus 로고
    • A randomised multicentre Phase II trial of capecitabine vs S-1 as first-line treatment in elderly patients with metastatic or recurrent unresectable gastric cancer
    • Lee JL, Kang YK, Kang HJ et al. A randomised multicentre Phase II trial of capecitabine vs S-1 as first-line treatment in elderly patients with metastatic or recurrent unresectable gastric cancer. Br. J. Cancer 99(4), 584-590 (2008).
    • (2008) Br. J. Cancer , vol.99 , Issue.4 , pp. 584-590
    • Lee, J.L.1    Kang, Y.K.2    Kang, H.J.3
  • 33
    • 38049047178 scopus 로고    scopus 로고
    • Capecitabine and oxaliplatin for advanced esophagogastric cancer
    • Upper Gastrointestinal Clinical Studies Group of the National Cancer Research Institute of the United Kingdom
    • Cunningham D, Starling N, Rao S et al.; Upper Gastrointestinal Clinical Studies Group of the National Cancer Research Institute of the United Kingdom. Capecitabine and oxaliplatin for advanced esophagogastric cancer. N. Engl. J. Med. 358(1), 36-46 (2008).
    • (2008) N. Engl. J. Med. , vol.358 , Issue.1 , pp. 36-46
    • Cunningham, D.1    Starling, N.2    Rao, S.3
  • 34
    • 63749118193 scopus 로고    scopus 로고
    • Capecitabine/cisplatin versus 5-fluorouracil/ cisplatin as first-line therapy in patients with advanced gastric cancer: A randomised Phase III noninferiority trial
    • Kang YK, Kang WK, Shin DB et al. Capecitabine/cisplatin versus 5-fluorouracil/ cisplatin as first-line therapy in patients with advanced gastric cancer: a randomised Phase III noninferiority trial. Ann. Oncol. 20(4), 666-673 (2009).
    • (2009) Ann. Oncol. , vol.20 , Issue.4 , pp. 666-673
    • Kang, Y.K.1    Kang, W.K.2    Shin, D.B.3
  • 35
    • 0036926036 scopus 로고    scopus 로고
    • Phase II study of capecitabine plus cisplatin as first-line chemotherapy in advanced gastric cancer
    • DOI 10.1093/annonc/mdf323
    • Kim TW, Kang YK, Ahn JH et al. Phase II study of capecitabine plus cisplatin as first-line chemotherapy in advanced gastric cancer. Ann. Oncol. 13, 1893-1898 (2002). (Pubitemid 36049952)
    • (2002) Annals of Oncology , vol.13 , Issue.12 , pp. 1893-1898
    • Kim, T.W.1    Kang, Y.K.2    Ahn, J.H.3    Chang, H.M.4    Yook, J.H.5    Oh, S.T.6    Kim, B.S.7    Lee, J.S.8
  • 36
    • 20044384872 scopus 로고    scopus 로고
    • Phase II study of capecitabine and cisplatin as first-line combination therapy in patients with gastric cancer recurrent after fluoropyrimidine-based adjuvant chemotherapy
    • DOI 10.1038/sj.bjc.6602336
    • Kang HJ, Chang HM, Kim TW et al. Phase II study of capecitabine and cisplatin as first-line combination therapy in patients with gastric cancer recurrent after fluoropyrimidine-based adjuvant chemotherapy. Br. J. Cancer 92(2), 246-251 (2005). (Pubitemid 40347314)
    • (2005) British Journal of Cancer , vol.92 , Issue.2 , pp. 246-251
    • Kang, H.J.1    Chang, H.M.2    Kim, T.W.3    Ryu, M.-H.4    Sohn, H.J.5    Yook, J.H.6    Oh, S.T.7    Kim, B.S.8    Lee, J.-S.9    Kang, Y.-K.10
  • 37
    • 34547132086 scopus 로고    scopus 로고
    • Combination chemotherapy with capecitabine (X) and cisplatin (P) as first Line treatment in advanced gastric cancer: Experience of 223 patients with prognostic factor analysis
    • DOI 10.1093/jjco/hyl134
    • Lee SS, Lee JL, Ryu MH et al. Combination chemotherapy with capecitabine (X) and cisplatin (P) as first line treatment in advanced gastric cancer: experience of 223 patients with prognostic factor analysis. Jpn. J. Clin. Oncol. 37(1), 30-37 (2007). (Pubitemid 47096440)
    • (2007) Japanese Journal of Clinical Oncology , vol.37 , Issue.1 , pp. 30-37
    • Lee, S.S.1    Lee, J.-L.2    Ryu, M.-H.3    Chang, H.M.4    Kim, T.W.5    Kang, H.-J.6    Kim, W.K.7    Lee, J.S.8    Kang, Y.-K.9
  • 39
    • 2342459741 scopus 로고    scopus 로고
    • A phase II study of capecitabine and docetaxel combination chemotherapy in patients with advanced gastric cancer
    • DOI 10.1038/sj.bjc.6601724
    • Park YH, Ryoo BY, Choi SJ, Kim HT. A Phase II study of capecitabine and docetaxel combination chemotherapy in patients with advanced gastric cancer. Br. J. Cancer 90(7), 1329-1333 (2004). (Pubitemid 38586256)
    • (2004) British Journal of Cancer , vol.90 , Issue.7 , pp. 1329-1333
    • Park, Y.H.1    Ryoo, B.-Y.2    Choi, S.-J.3    Kim, H.-T.4
  • 40
    • 33645315211 scopus 로고    scopus 로고
    • Docetaxel and capecitabine in patients with metastatic adenocarcinoma of the stomach and gastroesophageal junction: A Phase II study from the North Central Cancer Treatment Group
    • North Central Cancer Treatment Group
    • Giordano KF, Jatoi A, Stella PJ et al.; North Central Cancer Treatment Group. Docetaxel and capecitabine in patients with metastatic adenocarcinoma of the stomach and gastroesophageal junction: a Phase II study from the North Central Cancer Treatment Group. Ann. Oncol. 17(4), 652-656 (2006).
    • (2006) Ann. Oncol. , vol.17 , Issue.4 , pp. 652-656
    • Giordano, K.F.1    Jatoi, A.2    Stella, P.J.3
  • 42
    • 77951210082 scopus 로고    scopus 로고
    • Docetaxel and capecitabine for advanced gastric cancer: Phase II study investigating dose dependent efficacy in two patient cohorts
    • Presented at: Atlanta, GA, USA, 30 May-3 June
    • Thuss-Patience PC, Kretzschmar A, Dogan Y et al. Docetaxel and capecitabine for advanced gastric cancer: Phase II study investigating dose dependent efficacy in two patient cohorts. Presented at: 44th American Society of Clinical Oncology Annual Meeting. Atlanta, GA, USA, 30 May-3 June 2008.
    • (2008) 44th American Society of Clinical Oncology Annual Meeting
    • Thuss-Patience, P.C.1    Kretzschmar, A.2    Dogan, Y.3
  • 43
    • 33645732748 scopus 로고    scopus 로고
    • A Phase II study of capecitabine plus 3-weekly oxaliplatin as first-line therapy for patients with advanced gastric cancer
    • Park YH, Kim BS, Ryoo BY, Yang SH. A Phase II study of capecitabine plus 3-weekly oxaliplatin as first-line therapy for patients with advanced gastric cancer. Br. J. Cancer 94(7), 959-963 (2006).
    • (2006) Br. J. Cancer , vol.94 , Issue.7 , pp. 959-963
    • Park, Y.H.1    Kim, B.S.2    Ryoo, B.Y.3    Yang, S.H.4
  • 44
    • 34247602680 scopus 로고    scopus 로고
    • First-line treatment with oxaliplatin and capecitabine in patients with advanced or metastatic oesophageal cancer: A phase II study
    • DOI 10.1038/sj.bjc.6603750, PII 6603750
    • van Meerten E, Eskens FA, van Gameren EC, Doorn L, van der Gaast A. First-line treatment with oxaliplatin and capecitabine in patients with advanced or metastatic oesophageal cancer: a Phase II study. Br. J. Cancer 96(9), 1348-1352 (2007). (Pubitemid 46685802)
    • (2007) British Journal of Cancer , vol.96 , Issue.9 , pp. 1348-1352
    • Van Meerten, E.1    Eskens, F.A.L.M.2    Van Gameren, E.C.3    Doorn, L.4    Van Der Gaast, A.5
  • 45
    • 29844455992 scopus 로고    scopus 로고
    • Oxaliplatin and capecitabine in patients with metastatic adenocarcinoma of the esophagus, gastroesophageal junction and gastric cardia: A phase II study from the North Central Cancer Treatment Group
    • DOI 10.1093/annonc/mdj063
    • Jatoi A, Murphy BR, Foster NR et al; North Central Cancer Treatment Group. Oxaliplatin and capecitabine in patients with metastatic adenocarcinoma of the esophagus, gastroesophageal junction and gastric cardia: a Phase II study from the North Central Cancer Treatment Group. Ann. Oncol. 17(1), 29-34 (2006). (Pubitemid 43033836)
    • (2006) Annals of Oncology , vol.17 , Issue.1 , pp. 29-34
    • Jatoi, A.1    Murphy, B.R.2    Foster, N.R.3    Nikcevich, D.A.4    Alberts, S.R.5    Knost, J.A.6    Fitch, T.R.7    Rowland Jr., K.M.8
  • 46
    • 34347371390 scopus 로고    scopus 로고
    • Insights, challenges, and future directions in irinogenetics
    • DOI 10.1097/FTD.0b013e318068623b, PII 0000769120070600000001
    • Kim TW, Innocenti F. Insights, challenges, and future directions in irinogenetics. Ther. Drug Monit. 29(3), 265-270 (2007). (Pubitemid 47262254)
    • (2007) Therapeutic Drug Monitoring , vol.29 , Issue.3 , pp. 265-270
    • Kim, T.W.1    Innocenti, F.2
  • 47
    • 36348949060 scopus 로고    scopus 로고
    • A general review of the role of irinotecan (CPT11) in the treatment of gastric cancer
    • DOI 10.1007/BF02698032
    • Farhat FS. A general review of the role of irinotecan (CPT11) in the treatment of gastric cancer. Med. Oncol. 24(2), 137-146 (2007). (Pubitemid 350139221)
    • (2007) Medical Oncology , vol.24 , Issue.2 , pp. 137-146
    • Farhat, F.S.1
  • 50
    • 0035692526 scopus 로고    scopus 로고
    • A Phase II study of irinotecan with 5-fluorouracil and leucovorin in patients with previously untreated gastric adenocarcinoma
    • Blanke CD, Haller DG, Benson AB et al. A Phase II study of irinotecan with 5-fluorouracil and leucovorin in patients with previously untreated gastric adenocarcinoma. Ann. Oncol. 12(11), 1575-1580 (2001).
    • (2001) Ann. Oncol. , vol.12 , Issue.11 , pp. 1575-1580
    • Blanke, C.D.1    Haller, D.G.2    Benson, A.B.3
  • 53
    • 48849094297 scopus 로고    scopus 로고
    • Randomized Phase III study comparing irinotecan combined with 5-fluorouracil and folinic acid to cisplatin combined with 5-fluorouracil in chemotherapy naive patients with advanced adenocarcinoma of the stomach or esophagogastric junction
    • Dank M, Zaluski J, Barone C et al. Randomized Phase III study comparing irinotecan combined with 5-fluorouracil and folinic acid to cisplatin combined with 5-fluorouracil in chemotherapy naive patients with advanced adenocarcinoma of the stomach or esophagogastric junction. Ann. Oncol. 19(8), 1450-1457 (2008).
    • (2008) Ann. Oncol. , vol.19 , Issue.8 , pp. 1450-1457
    • Dank, M.1    Zaluski, J.2    Barone, C.3
  • 55
    • 33646496600 scopus 로고    scopus 로고
    • A Phase i and II study of 2-weekly irinotecan with capecitabine in advanced gastroesophageal adenocarcinoma
    • Burge ME, Smith D, Topham C et al. A Phase I and II study of 2-weekly irinotecan with capecitabine in advanced gastroesophageal adenocarcinoma. Br. J. Cancer 94(9), 1281-1286 (2006).
    • (2006) Br. J. Cancer , vol.94 , Issue.9 , pp. 1281-1286
    • Burge, M.E.1    Smith, D.2    Topham, C.3
  • 57
    • 67349126229 scopus 로고    scopus 로고
    • A Phase II trial evaluating capecitabine and irinotecan as second line treatment in patients with oesophago-gastric cancer who have progressed on, or within 3 months of platinum-based chemotherapy
    • Leary A, Assersohn L, Cunningham D et al. A Phase II trial evaluating capecitabine and irinotecan as second line treatment in patients with oesophago-gastric cancer who have progressed on, or within 3 months of platinum-based chemotherapy. Cancer Chemother. Pharmacol. 64(3), 455-462 (2009).
    • (2009) Cancer Chemother. Pharmacol. , vol.64 , Issue.3 , pp. 455-462
    • Leary, A.1    Assersohn, L.2    Cunningham, D.3
  • 58
    • 77956901182 scopus 로고    scopus 로고
    • Role of low dose capecitabine combined to irinotecan in advanced and metastatic gastric cancer
    • In press
    • Farhat FS, Kattan J, Chahine GY et al. Role of low dose capecitabine combined to irinotecan in advanced and metastatic gastric cancer. Med. Oncol. (2009) (In press).
    • (2009) Med. Oncol.
    • Farhat, F.S.1    Kattan, J.2    Chahine, G.Y.3
  • 59
    • 77949326012 scopus 로고    scopus 로고
    • A randomized multicenter Phase II study comparing capecitabine with irinotecan or cisplatin in metastatic adenocarcinoma of the stomach or esophagogastric junction
    • for the Arbeitsgemeinschaft Internistische Onkologie, Germany
    • Moehler M, Kanzler S, Geissler M et al.; for the Arbeitsgemeinschaft Internistische Onkologie, Germany. A randomized multicenter Phase II study comparing capecitabine with irinotecan or cisplatin in metastatic adenocarcinoma of the stomach or esophagogastric junction. Ann. Oncol. 21(1), 71-77 (2010).
    • (2010) Ann. Oncol. , vol.21 , Issue.1 , pp. 71-77
    • Moehler, M.1    Kanzler, S.2    Geissler, M.3
  • 60
    • 33745674902 scopus 로고    scopus 로고
    • Epidermal growth factor receptor tyrosine kinase inhibitors: Present and future role in gastrointestinal cancer treatment: A review
    • DOI 10.1634/theoncologist.11-6-602
    • Arnold D, Peinert S, Voigt W, Schmoll HJ. Epidermal growth factor receptor tyrosine kinase inhibitors: present and future role in gastrointestinal cancer treatment: a review. Oncologist 11(6), 602-611 (2006). (Pubitemid 43967615)
    • (2006) Oncologist , vol.11 , Issue.6 , pp. 602-611
    • Arnold, D.1    Peinert, S.2    Voigt, W.3    Schmoll, H.-J.4
  • 62
    • 70350204423 scopus 로고    scopus 로고
    • Efficacy results from the ToGA trial: A Phase III study of trastuzumab added to standard chemotherapy (CT) in first-line human epidermal growth factor receptor 2 (HER2)-positive advanced gastric cancer (GC)
    • Abstract LBA4509
    • Van Cutsem E, Kang Y, Chung H et al. Efficacy results from the ToGA trial: a Phase III study of trastuzumab added to standard chemotherapy (CT) in first-line human epidermal growth factor receptor 2 (HER2)-positive advanced gastric cancer (GC). J. Clin. Oncol. 27(Suppl. 20), 155 (2009) (Abstract LBA4509).
    • (2009) J. Clin. Oncol. , vol.27 , Issue.SUPPL. 20 , pp. 155
    • Van Cutsem, E.1    Kang, Y.2    Chung, H.3
  • 63
    • 74649083025 scopus 로고    scopus 로고
    • Targeting gastric cancer with trastuzumab: New clinical practice and innovative developments to overcome resistance
    • Roukos DH. Targeting gastric cancer with trastuzumab: new clinical practice and innovative developments to overcome resistance. Ann. Surg. Oncol. (2009) 71(1), 14-17 (2010).
    • (2010) Ann. Surg. Oncol. (2009) , vol.71 , Issue.1 , pp. 14-17
    • Roukos, D.H.1
  • 64
    • 40549135647 scopus 로고    scopus 로고
    • More controversy than ever - Challenges and promises towards personalized treatment of gastric cancer
    • Liakakos T, Roukos DH. More controversy than ever - challenges and promises towards personalized treatment of gastric cancer. Ann. Surg. Oncol. 15, 956-960 (2008).
    • (2008) Ann. Surg. Oncol. , vol.15 , pp. 956-960
    • Liakakos, T.1    Roukos, D.H.2
  • 65
    • 66749140976 scopus 로고    scopus 로고
    • Mea culpa with cancer-targeted therapy: New thinking and new agents design for novel, causal networks-based, personalized biomedicine
    • Roukos DH. Mea culpa with cancer-targeted therapy: new thinking and new agents design for novel, causal networks-based, personalized biomedicine. Expert Rev. Mol. Diagn. 9(3), 217-221 (2009).
    • (2009) Expert Rev. Mol. Diagn. , vol.9 , Issue.3 , pp. 217-221
    • Roukos, D.H.1


* 이 정보는 Elsevier사의 SCOPUS DB에서 KISTI가 분석하여 추출한 것입니다.