Phosphorylation of VACM-1/Cul5 by protein kinase A regulates its neddylation and antiproliferative effect

Journal of Biological Chemistry

Volumn 285, Issue 7, 2010, Pages 4883-4895

  Bradley, Shirley E ^a   Johnson, Alyssa E ^a   Le, Isabelle P ^a   Oosterhouse, Elizabeth ^a   Hledin, Michael P ^a   Marquez, Gabriel A ^a   Burnatowska Hledin, Maria ^a  

^a HOPE COLLEGE   (United States)

Author keywords

[No Author keywords available]

Indexed keywords

ANTI-CANCER THERAPEUTICS; ANTIPROLIFERATIVE EFFECT; CANCER CELL LINES; CELL LYSATES; CELLULAR GROWTH; CELLULAR PROLIFERATIONS; CONTROL-CELL; FORSKOLIN; IN-CELL; IN-VITRO; PHORBOL 12 MYRISTATE 13 ACETATES; PHOSPHORYLATION SITES; POST-TRANSLATIONAL MODIFICATIONS; PROTEIN CONCENTRATIONS; PROTEIN KINASE; PROTEIN KINASE A; PROTEIN MODIFICATIONS; PROTEIN SEQUENCES; RAT ADRENAL MEDULLARY ENDOTHELIAL CELLS; SMALL INTERFERING RNA; SPECIFIC SITES; STRUCTURE-FUNCTION ANALYSIS; TRANSFECTED CELLS; WESTERN-BLOT ANALYSIS;

ANTIBODIES; BLOOD VESSEL PROSTHESES; CELL CULTURE; CELL PROLIFERATION; GENE EXPRESSION; GROWTH KINETICS; NUCLEIC ACIDS; OLIGONUCLEOTIDES; PHOSPHORYLATION; RNA; SELF ASSEMBLY;

ENDOTHELIAL CELLS;

ANTINEOPLASTIC AGENT; COMPLEMENTARY DNA; CULLIN; CYCLIC AMP DEPENDENT PROTEIN KINASE; FORSKOLIN; MITOGEN ACTIVATED PROTEIN KINASE; MONOCLONAL ANTIBODY; NEDD8 PROTEIN; PHORBOL 13 ACETATE 12 MYRISTATE; PROTEIN KINASE C; SMALL INTERFERING RNA; UNCLASSIFIED DRUG; VASOPRESSIN ACTIVATED CALCIUM MOBILIZING PROTEIN 1;

ADRENAL MEDULLA; AMINO ACID SEQUENCE; ANIMAL CELL; ARTICLE; CANCER CELL CULTURE; CELL GROWTH; CELL LYSATE; CELL PROLIFERATION; CONSENSUS SEQUENCE; CONTROLLED STUDY; CYTOMEGALOVIRUS; DRUG DESIGN; DRUG TARGETING; ENDOTHELIUM CELL; ENZYME ACTIVITY; ENZYME INDUCTION; ENZYME REGULATION; GENE MUTATION; GENETIC TRANSFECTION; IMMUNOPRECIPITATION; IN VITRO STUDY; INHIBITION KINETICS; NONHUMAN; PRIORITY JOURNAL; PROTEIN EXPRESSION; PROTEIN MODIFICATION; PROTEIN PHOSPHORYLATION; PROTEIN PROCESSING; RAT; STRUCTURE ACTIVITY RELATION; WESTERN BLOTTING;

ANIMALS; BLOTTING, WESTERN; CELL LINE; CELL PROLIFERATION; CULLIN PROTEINS; CYCLIC AMP-DEPENDENT PROTEIN KINASES; ENZYME ACTIVATION; IMMUNOPRECIPITATION; MUTAGENESIS, SITE-DIRECTED; PHOSPHORYLATION; PROTEIN PROCESSING, POST-TRANSLATIONAL; RATS; RECEPTORS, VASOPRESSIN; RNA, SMALL INTERFERING; TETRADECANOYLPHORBOL ACETATE; UBIQUITINS;

CYTOMEGALOVIRUS; RATTUS;

EID: 77951197939     PISSN: 00219258     EISSN: 1083351X     Source Type: Journal    
DOI: 10.1074/jbc.M109.085225     Document Type: Article

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