Renal cell carcinoma in young adults: A study of 130 cases and a review of previous series

Urologia Internationalis

Volumn 84, Issue 3, 2010, Pages 292-300

  López, José I ^a   Moreno, Virginia ^a   García, Huberto ^b   Antón, Iosu ^c   Robles, Antonio ^d   Oñate, Juan M ^e   Baños, Ángeles ^f   Escandón, Jorge ^g   Ugalde, Aitziber ^a  

^a UNIVERSITY OF THE BASQUE COUNTRY UPV EHU   (Spain)

^b UNIVERSIDAD COMPLUTENSE DE MADRID   (Spain)

^c POVISA   (Spain)

^d UNIVERSITY OF SEVILLE   (Spain)

^e UNIVERSITY OF VALLADOLID   (Spain)

^f HOSPITAL UNIVERSITARIO DE BURGOS   (Spain)

^g UNIVERSITY OF VALENCIA   (Spain)

Author keywords

Clear cell cancer; Immunohistochemical markers; Papillary cancer; Renal cancer histology; Renal cell carcinoma; WHO classification of renal tumors; Young cancer patients

Indexed keywords

CD15 ANTIGEN; COMMON ACUTE LYMPHOBLASTIC LEUKEMIA ANTIGEN; CYTOKERATIN; CYTOKERATIN 34 BETA E 12; CYTOKERATIN 7; STEM CELL FACTOR RECEPTOR; UNCLASSIFIED DRUG; UVOMORULIN;

ADOLESCENT; ADULT; ARTICLE; CHILD; CLEAR CELL CARCINOMA; FEMALE; HISTOPATHOLOGY; HUMAN; HUMAN TISSUE; IMMUNOHISTOCHEMISTRY; KIDNEY CARCINOMA; MAJOR CLINICAL STUDY; MALE; PAPILLARY CARCINOMA; PRIORITY JOURNAL; SCHOOL CHILD; TUMOR VOLUME;

ADOLESCENT; ADULT; CARCINOMA, RENAL CELL; FEMALE; HUMANS; IMMUNOHISTOCHEMISTRY; KIDNEY NEOPLASMS; MALE; RETROSPECTIVE STUDIES; YOUNG ADULT;

EID: 77951108667     PISSN: 00421138     EISSN: None     Source Type: Journal    
DOI: 10.1159/000288231     Document Type: Article

References (32)

1. Jemal A, Siegel R, Ward E, Murray T, Xu J, Thun MJ: Cancer statistics, 2007. CA Cancer J Clin 2007; 57: 43-66.
2. Lopez-Beltran A, Scarpelli M, Montironi R, Kirkali Z: 2004 WHO classification of the renal tumors of the adults. Eur Urol 2006; 49: 798-805.
3. Murphy WM, Grignon DJ, Perlman EJ: AFIP Atlas of Tumor Pathology, Series 4. Tumors of the Kidney, Bladder, and Related Urinary Structures. Washington, American Registry of Pathology, 2004, pp 101-109.
4. Lieber MM, Tomera FM, Taylor WF, Farrow GM: Renal adenocarcinoma in young adults: survival and variables affecting prognosis. J Urol 1981; 125: 164-168.
5. Schiff M Jr, Herter G, Lytton B: Renal adenocarcinoma in young adults. Urology 1985; 25: 357-359.
6. Rainwater LM, Zincke H, Farrow GM, Gonchoroff NJ: Renal cell carcinoma in young and old patients. Urology 1991; 38: 1-5.
7. Boykin WH, Bright KE, Zeidman EJ, Thompson IM: Renal tumors in young adults. Urology 1992; 40: 503-505.
8. Fernández Gómez JM, Rábade Rey CJ, Pérez García FJ, Sahagun-Angüello JL, Martínez Gómez FJ, Alonso-Sáinz F: Renal adenocarcinoma in young patients (in Spanish). Actas Urol Esp 1997; 21: 22-27.
9. Asanuma H, Nakai H, Takeda M, et al: Renal cell carcinoma in children: experience at a single institution in Japan. J Urol 1999; 162: 1402-1405.
10. Yusim I, Mermershtain W, Neulander E, Eidelberg I, Gusakova I, Kaneti J: Influence of age on the prognosis of patients with renal cell carcinoma (RCC). Onkologie 2002; 25: 548-550.
11. Maoudouni S, En-Nia I, Rioux-Leclerq N, et al: Renal cell carcinoma before the age of 40: prognostic factors. Prog Urol 2002; 12: 575-578.
12. Rodriguez A, Tazi H, Patard JJ, Lobel B: Le cancer du rein de l'adulte de moins de 40 ans: un cancer particulier? Incidence, évolution et revue de la littérature. Ann Urol (Paris) 2003; 37: 155-159.
13. Sánchez-Ortiz RF, Rosser CJ, Madsen LT, Swanson DA, Wood CG: Young age is an independent prognostic factor for survival of sporadic renal cell carcinoma. J Urol 2004; 171: 2160-2165.
14. Abou El Fettouh HI, Cherullo EE, El-Jack M, Al Maslamani YA, Novick AC: Sporadic renal cell carcinoma in young adults: presentation, treatment, and outcome. Urology 2002; 60: 806-810.
15. Eggener SE, Rubenstein JR, Smith ND, et al: Renal tumors in young adults. J Urol 2004; 171: 106-110.
16. Goetzl MA, Desai M, Mansukhani M, et al: Natural history and clinical outcome of sporadic renal cortical tumors diagnosed in the young adult. Urology 2004; 63: 41-45.
17. Gillett MD, Cheville JC, Karnes J, et al: Comparison of presentation and outcome for patients to 40 and 60 to 70 years old with solid renal masses. J Urol 2005; 173: 1893-1896.
18. Taccoen X, Valeri A, Descotes JL, et al: Renal cell carcinoma in adults 40 years old or less: young age is an independent prognostic factor for cancer-specific survival. Eur Urol 2007; 51: 980-987.
19. Zugor V, Fridel S, Lausen B, Schott GE, Kühn R, Labanaris AP: Renal cell carcinoma under years of age: comparison of survival rates for symptomatic and asymptomatic patients. Int Urol Nephrol 2008; 40: 289-293.
20. Argani P, Ladanyi M: Translocation carcinomas of the kidney. Clin Lab Med 2005; 25: 363-378.
21. Gobbo S, Eble JN, Grignon DJ, et al: Clear cell papillary renal cell carcinoma: a distinct histopathologic and molecular genetic entity. Am J Surg Pathol 2008; 32: 1239-1245.
22. Gobbo S, Eble JN, MacLennan GT, et al: Renal cell carcinomas with papillary architecture and clear cell components: the utility of immunohistochemistry and cytogenetical analyses in differential diagnosis. Am J Surg Pathol 2008; 32: 1780-1786.
23. Fuhrman SA, Lasky LC, Limas C: Prognostic significance of morphologic parameters in renal cell carcinoma. Am J Surg Pathol 1982; 6: 655-663.
24. Greene FL, Page DL, Fleming ID, et al (eds): AJCC Cancer Staging Manual, ed 6. New York, Springer, 2002.
25. Jonasch E, Tannir NM: Adjuvant and neoadjuvant therapy in renal cell carcinoma. Cancer J 2008; 14: 315-319.
26. Amin MB, Paner GP, Alvarado-Cabrero I, et al: Chromophobe renal cell carcinoma: histomorphologic characteristics and evaluation of conventional pathologic prognostic parameters in 145 cases. Am J Surg Pathol 2008; 32: 1822-1834.
27. Fuzesi L, Gunawan B, Bergmann F, Tack S, Braun S, Jakse G: Papillary renal cell carcinoma with clear cell cytomorphology and chromosomal loss of 3p. Histopathology 1999; 35: 157-161.
28. Salama ME, Worsham MJ, de Peralta-Venturina M: Malignant papillary renal tumors with extensive clear cell change. A molecular analysis by microsatellite analysis and fluorescence in situ hybridization. Arch Pathol Lab Med 2003; 127: 1176-1181.
29. Tickoo SK, de Peralta-Venturina MN, Harik LR, Worcester HD, Salama ME, Young AN, Moch H, Amin MB: Spectrum of epithelial neoplasms in end-stage renal disease. An experience from 66 tumor-bearing kidneys with emphasis on histologic patterns distinct from those in sporadic adult renal neoplasia. Am J Surg Pathol 2006; 30: 141-153.
30. Rohan SM, Dudas ME, Gopalan A, Fine SW, Reuter VE, Tickoo SK: Clear cell papillary renal cell carcinoma: a distinct entity or a variant of clear cell renal cell carcinoma? Mod Pathol 2009; 22: 191A.
31. Aydin H, Sercia L, Magi-Galluzzi C, Zhou M: Expanding the morphological spectrum of clear cell papillary renal cell carcinoma, a distinct renal cell carcinoma subtype. Mod Pathol 2009; 22: 158A.
32. Zhou M, Roma A, Magi-Galluzzi C: The usefulness of immunohistochemical markers in the differential diagnosis of renal neoplasms. Clin Lab Med 2005; 25: 247-257.