Cardiovascular and metabolic effects of high-dose insulin in a porcine septic shock model

Academic Emergency Medicine

Volumn 17, Issue 4, 2010, Pages 429-435

  Holger, Joel S ^a   Dries, David J ^a   Barringer, Kelly W ^a   Peake, Benjamin J ^a,c   Flottemesch, Thomas J ^b   Marini, John J ^a  

^a REGIONS HOSPITAL   (United States)

^b HEALTHPARTNERS RESEARCH FOUNDATION   (United States)

^c UNIVERSITY OF MINNESOTA   (United States)

Author keywords

Critical care; High dose insulin; Myocardial depression; Sepsis; Septic shock

Indexed keywords

ESCHERICHIA COLI ENDOTOXIN; ESCHERICHIA COLI LIPOPOLYSACCHARIDE; INSULIN; LACTIC ACID;

ANIMAL EXPERIMENT; ANIMAL MODEL; ARTICLE; CARDIOVASCULAR EFFECT; CARDIOVASCULAR FUNCTION; CENTRAL VENOUS PRESSURE; CONTINUOUS INFUSION; CONTROLLED STUDY; DISEASE SEVERITY; DOSE RESPONSE; DRUG DOSE INCREASE; DRUG DOSE TITRATION; DRUG MECHANISM; DRUG MEGADOSE; ESCHERICHIA COLI; HEART INDEX; HEART OUTPUT; HEART RATE; HEMODYNAMICS; INTENSIVE CARE; LACTATE BLOOD LEVEL; LUNG ARTERY PRESSURE; LUNG VASCULAR RESISTANCE; MEAN ARTERIAL PRESSURE; METABOLIC PARAMETERS; NONHUMAN; OUTCOMES RESEARCH; OXYGEN CONSUMPTION; OXYGEN SATURATION; PRIORITY JOURNAL; RANDOMIZATION; RESUSCITATION; SEPSIS; SEPTIC SHOCK; SURVIVAL; SWINE; SYSTEMIC VASCULAR RESISTANCE;

ANIMALS; BLOOD PRESSURE; CARDIAC OUTPUT; CARDIOVASCULAR SYSTEM; CONFIDENCE INTERVALS; DISEASE MODELS, ANIMAL; DOSE-RESPONSE RELATIONSHIP, DRUG; HEART RATE; INFUSIONS, INTRAVENOUS; INSULIN; LACTATES; MYOCARDIAL CONTRACTION; OXYGEN; OXYGEN CONSUMPTION; PROBABILITY; RANDOM ALLOCATION; REFERENCE VALUES; RISK FACTORS; SHOCK, SEPTIC; SURVIVAL RATE; SWINE; VASCULAR RESISTANCE;

EID: 77951088223     PISSN: 10696563     EISSN: 15532712     Source Type: Journal    
DOI: 10.1111/j.1553-2712.2010.00695.x     Document Type: Article

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