OCT-4 expression in follicular and luteal phase endometrium: a pilot study

Reproductive Biology and Endocrinology

Volumn 8, Issue , 2010, Pages

  Bentz, Eva Katrin ^a   Kenning, Marina ^a   Schneeberger, Christian ^a   Kolbus, Andrea ^a   Huber, Johannes C ^a   Hefler, Lukas A ^b   Tempfer, Clemens B ^b  

^a MEDICAL UNIVERSITY OF VIENNA   (Austria)

^b UNIV KLIN FÜR FRAUENHEILKUNDE   (Austria)

Author keywords

[No Author keywords available]

Indexed keywords

MESSENGER RNA; OCTAMER TRANSCRIPTION FACTOR 4; BIOLOGICAL MARKER; POU5F1 PROTEIN, HUMAN;

ADULT; ARTICLE; COHORT ANALYSIS; CONTROLLED STUDY; ENDOMETRIUM; FEMALE; FOLLICULAR PHASE; GENE EXPRESSION; HORMONAL REGULATION; HUMAN; HUMAN TISSUE; HYSTEROSCOPY; IMMUNOHISTOCHEMISTRY; LUTEAL PHASE; MAJOR CLINICAL STUDY; PILOT STUDY; PROSPECTIVE STUDY; PROTEIN ANALYSIS; PROTEIN EXPRESSION; PROTEIN FUNCTION; REVERSE TRANSCRIPTION POLYMERASE CHAIN REACTION; UTERUS FUNCTION; ADULT STEM CELL; COMPARATIVE STUDY; CYTOLOGY; GENE EXPRESSION REGULATION; GENETICS; METABOLISM;

ADULT; ADULT STEM CELLS; BIOLOGICAL MARKERS; COHORT STUDIES; ENDOMETRIUM; FEMALE; FOLLICULAR PHASE; GENE EXPRESSION REGULATION; HUMANS; HYSTEROSCOPY; IMMUNOHISTOCHEMISTRY; LUTEAL PHASE; OCTAMER TRANSCRIPTION FACTOR-3; PILOT PROJECTS; REVERSE TRANSCRIPTASE POLYMERASE CHAIN REACTION; RNA, MESSENGER;

EID: 77951065485     PISSN: None     EISSN: 14777827     Source Type: Journal    
DOI: 10.1186/1477-7827-8-38     Document Type: Article

References (17)

1. Scholer H, Rupert S, Suzuki N, Chowdhury K, Gruss P. New type of POU domain in germ line-specific protein Oct-4. Nature 1990, 344:435-439. 10.1038/344435a0, 1690859.
2. Phillips K, Luisi B. The virtuoso of versatility: POU proteins that flex to fit. J Mol Biol 2000, 302(5):1023-1039. 10.1006/jmbi.2000.4107, 11183772.
3. Latchman DS. Transcription factors: an overview. Int J Biochem Cell Biol 1997, 29(12):1305-1312. 10.1016/S1357-2725(97)00085-X, 9570129.
4. Lee TI, Young RA. Transcription of eukaryotic protein-coding genes. Ann Rev Genet 2000, 34:77-137. 10.1146/annurev.genet.34.1.77, 11092823.
5. Pesce M, Scholer HR. Oct-4: Gatekeeper in the Beginnings of Mammalian Development. Stem Cells 2001, 19(4):271-278. 10.1634/stemcells.19-4-271, 11463946.
6. Scholer H, Dressler G, Balling R, Rohdewold H, Gruss P. Oct-4: a germ-line specific transcription factor mapping to the mouse t-complex. EMBO J 1990, 9:2185-2195. 551941, 2357966.
7. Niwa H, Miyazaki J, Smith A. Quantitative expression of Oct-3/4 defines differentiation, dedifferentiation, and self-renewal of ES-cells. Nature Genet 2000, 24:372-376. 10.1038/74199, 10742100.
8. Lamoury F, Croitoru-Lamoury J, Brew B. Undifferentiated mouse mesenchymal stem cells spontaneously express neural and stem cell markers Oct-4 and Rex-1. Cytotherapy 2006, 8(3):228-242. 10.1080/14653240600735875, 16793732.
9. Gidekel S, Pizov G, Bergman Y, Pikarski E. Oct-3/4 is a dose-dependent oncogenic fate determinant. Cancer Cell 2003, 4:361-370. 10.1016/S1535-6108(03)00270-8, 14667503.
10. Jin T, Branch DR, Zhang X, Youngson B, Goss PE. Examination of POU homebox gene expression in human breast cancer cells. Int J Cancer 1999, 81:104-112. 10.1002/(SICI)1097-0215(19990331)81:1<104::AID-IJC18>3.0.CO;2-Q, 10077160.
11. Monk M, Holding C. Human embryonic genes re-expressed in cancer cells. Oncogene 2001, 20:8085-8091. 10.1038/sj.onc.1205088, 11781821.
12. Matthai C, Horvat R, Noe M, Nagele F, Radjabi A, van Trotsenburg M, Huber J, Kolbus A. Oct-4 expression in human endometrium. Mol Hum Reprod 2006, 12:7-10. 10.1093/molehr/gah254, 16421218.
13. Cho N, Park Y, Kim Y, Yang H, Kim S. Lifetime expression of stem cell markers in the uterine endometrium. Fertil Steril 2004, 81(2):403-407. 10.1016/j.fertnstert.2003.07.015, 14967381.
14. Taylor HS. Endometrial cells derived from donor stem cells in bone marrow transplant recipients. JAMA 2004, 292:81-85. 10.1001/jama.292.1.81, 15238594.
15. Chan RW, Schwab KE, Gargett CE. Clonogenicity of human endometrial epithelial and stromal cells. Biol Reprod 2004, 70:1738-1750. 10.1095/biolreprod.103.024109, 14766732.
16. Lengner CJ, Camargo FD, Hochedlinger K, Welstead GG, Zaidi S, Gokhale S. Oct4 expression is not required for mouse somatic stem cell self-renewal. Cell Stem Cell 2007, 1(4):401-415.
17. Remmele W, Stegner HE. Recommendation for uniform definition of an immunoreactive score (IRS) for immunohistochemical estrogen receptor detection (ER-ICA) in breast cancer tissue. Pathologe 1987, 8(3):138-140.