A multipathway phosphoproteomic signaling network model of idiosyncratic drug- and inflammatory cytokine-induced toxicity in human hepatocytes

Proceedings of the 31st Annual International Conference of the IEEE Engineering in Medicine and Biology Society: Engineering the Future of Biomedicine, EMBC 2009

Volumn , Issue , 2009, Pages 5452-5455

  Cosgrove, Benjamin D ^a   Alexopoulos, Leonidas G ^b   Saez Rodriguez, Julio ^c   Griffith, Linda G ^d   Lauffenburger, Douglas A ^d  

^a STANFORD UNIVERSITY SCHOOL OF MEDICINE   (United States)

^b NATIONAL TECHNICAL UNIVERSITY OF ATHENS   (Greece)

^c HARVARD MEDICAL SCHOOL   (United States)

^d Massachusetts Institute of Technology Cambridge   (United States)

Author keywords

[No Author keywords available]

Indexed keywords

ANIMAL CELL CULTURE; CELL CULTURE; CELL DEATH; LEAST SQUARES APPROXIMATIONS; SIGNALING; TOXICITY;

ACCURATE PREDICTION; CELL CULTURE MODELS; INFLAMMATORY CYTOKINES; PARTIAL LEAST SQUARES REGRESSION; PRIMARY HUMAN HEPATOCYTES; SIGNALING MECHANISMS; SIGNALING NETWORKS; SIGNALING PATHWAYS;

CELL SIGNALING;

EID: 77951005730     PISSN: None     EISSN: None     Source Type: Conference Proceeding    
DOI: 10.1109/IEMBS.2009.5334019     Document Type: Conference Paper

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