Qualitative profile and quantitative determination of flavonoids from Crocus sativus L. petals by LC-MS/MS

Natural Product Communications

Volumn 3, Issue 12, 2008, Pages 2013-2016

  Montoro, Paola ^a   Tuberoso, Carlo I G ^b   Maldini, Mariateresa ^a   Cabras, Paolo ^b   Pizza, Cosimo ^a  

^a UNIVERSITY OF SALERNO   (Italy)

^b UNIVERSITY OF CAGLIARI   (Italy)

Author keywords

Crocus sativus; Kaempferol; LC ESI MS; LC MS MS; Quercetin

Indexed keywords

ANTIOXIDANT; CROCUS SATIVUS EXTRACT; FLAVONOID; ISORHAMNETIN 3,7 DI O BETA DEXTRO GLUCOPYRANOSIDE; ISORHAMNETIN3 O BETA DEXTRO GLUCOPYRANOSIDE; KAEMPFEROL 3 O BETA DEXTRO (2 O BETA DEXTRO 6 O ACETYLGLUCOSYL)GLUCOPYRANOSIDE; KAEMPFEROL 3 O BETA DEXTRO (2 O BETA DEXTRO GLUCOSYL)GLUCOPYRANOSIDE; KAEMPFEROL 3 O BETA DEXTRO GLUCOPYRANOSIDE; KAEMPFEROL 3,7 DI O BETA DEXTRO GLUCOPYRANOSIDE; KAEMPFEROL 7 O BETA DEXTRO GLUCOPYRANOSIDE; KAEMPFEROL DERIVATIVE; QUERCETIN 3 O BETA DEXTRO GLUCOPYRANOSIDE; QUERCETIN 3,7 DI O BETA DEXTRO GLUCOPYRANOSIDE; QUERCETIN DERIVATIVE; UNCLASSIFIED DRUG;

ARTICLE; CROCUS; DRUG ACETYLATION; DRUG DETERMINATION; DRUG IDENTIFICATION; DRUG ISOLATION; ELECTROSPRAY MASS SPECTROMETRY; GLYCOSYLATION; ION TRAP MASS SPECTROMETRY; LIQUID CHROMATOGRAPHY; NONHUMAN; PETAL; QUALITATIVE ANALYSIS; QUANTITATIVE ANALYSIS; SPICE;

CROCUS SATIVUS;

EID: 77950997837     PISSN: 1934578X     EISSN: 15559475     Source Type: Journal    
DOI: 10.1177/1934578x0800301215     Document Type: Article

References (17)

1. (a) Fernandez, JA. (2004) Biology, biotechnology and biomedicine of saffron. Recent Research Developments in Plant Science, 2 127-159;
2. (b) Rios JL, Recio MC, Giner RM, Manets S. (1996) An update review of saffron and its active constituents. Phytotheapy Research, 10, 189-193;
3. (c) Xi L, Qian Z. (2006) Pharmacological properties of crocetin and crocin (digentiobiosyl esters of crocetin) from saffron, Natural Product Communications, 1, 65-75.
4. (a) Li CY, Lee EJ, Wu TS. (2004) Antityrosinase principles and constituents of the petals of Crocus sativus. Journal of Natural Products, 67, 437-440;
5. (b) Rice-Evans CA, Miller NJ, Paganga G. (1997) Antioxidant properties of phenolic compounds. Trends in Plant Science, 2, 152-159.
6. (a) Cao G, Sofic E, Prior RL. (1997) Antioxidant and pro-oxidant behavior of flavonoids: structure-activity relationships. Free Radical Biology and Medicine, 22, 749-760;
7. (b) Rice-Evans CA, Miller NJ, Panaga G. (1996) Structure-antioxidant activity relationships of flavonoids and phenolic acids. Free Radical Biology and Medicine, 20, 933-956;
8. (c) Lien EJ, Ren S, Bui H, Wang R. (1999) Quantitative structure-activity relationship analysis of phenolic antioxidants. Free Radical Biology and Medicine, 26, 285-294;
9. (d) Montoro P, Braca A, Pizza C, De Tommasi N. (2005) Structure-antioxidant activity relationships of flavonoids isolated from different plant species. Food Chemistry, 92, 349-355.
10. ICH Q2B, International Conference on Harmonisation, London, 1995.
11. (a) Li X, Xiong Z, Ying X, Cui L, Zhu W, Li F. (2006) A rapid ultra-performance liquid chromatography-electrospray ionization tandem mass spectrometric method for the qualitative and quantitative analysis of the constituents of the flower of Trollius ledibouri Reichb. Analytica Chimica Acta, 580, 170-180;
12. (b) Benavides A, Montoro P, Bassarello C, Piacente S, Pizza C. (2006) Catechin derivatives in Jatropha macrantha stems: Characterisation and LC/ESI/MS/MS quali-quantitative analysis. Journal of Pharmaceutical and Biomedical Analysis, 40, 639-647;
13. (c) Montoro P, Tuberoso CIG, Perrone A, Piacente S, Cabras P, Pizza C. (2006) Characterisation by liquid chromatography -electrospray tandem mass spectrometry of anthocyanins in extracts of Myrtus communis L. berries used for the preparation of myrtle liqueur. Journal of Chromatography A, 1112, 232-240.
14. Merfort I, Wendisch D. (1992) New flavonoid glycosides from Arnicae flos DAB 9. Planta Medica, 58, 355-357.
15. Grouiller A, Pacheco H. (1967) Flavonoid compounds. VI. Nuclear magnetic resonance spectra of some O-glucosylflavonals, their aglycons and three synthetic mono- and di- O -glucosylflavanones. Bulletin de la Societe Chimique de France, 6, 1938-1943.
16. Nawwar MAM, El-Mousallamy AMD, Barakat HH. (1989) Quercetin 3-glycosides from the leaves of Solanum nigrum. Phytochemistry, 28, 1755-1757.
17. Senatore F, D'Agostino M, Dini I. (2000) Flavonoid glycosides of Barbarea vulgaris L. (Brassicaceae). Journal of Agricultural and Food Chemistry, 48, 2659-2662.